AP2987A - Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate - Google Patents
Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphateInfo
- Publication number
- AP2987A AP2987A AP2011005835A AP2011005835A AP2987A AP 2987 A AP2987 A AP 2987A AP 2011005835 A AP2011005835 A AP 2011005835A AP 2011005835 A AP2011005835 A AP 2011005835A AP 2987 A AP2987 A AP 2987A
- Authority
- AP
- ARIPO
- Prior art keywords
- hydroxymethyloxazolidin
- methyltetrazol
- pyridin
- fluorophenyl
- crystalline form
- Prior art date
Links
- UAXDUQWXEJLTSR-UTONKHPSSA-N (5r)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one;phosphoric acid Chemical compound OP(O)(O)=O.CN1N=NC(C=2N=CC(=CC=2)C=2C(=CC(=CC=2)N2C(O[C@@H](CO)C2)=O)F)=N1 UAXDUQWXEJLTSR-UTONKHPSSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14940209P | 2009-02-03 | 2009-02-03 | |
PCT/US2010/023122 WO2010091131A1 (en) | 2009-02-03 | 2010-02-03 | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2011005835A0 AP2011005835A0 (en) | 2011-08-31 |
AP2987A true AP2987A (en) | 2014-09-30 |
Family
ID=42289775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2011005835A AP2987A (en) | 2009-02-03 | 2010-02-03 | Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate |
Country Status (29)
Country | Link |
---|---|
US (6) | US8426389B2 (xx) |
EP (1) | EP2393808B1 (xx) |
JP (1) | JP5584705B2 (xx) |
KR (3) | KR101918678B1 (xx) |
CN (2) | CN102439006A (xx) |
AP (1) | AP2987A (xx) |
AU (1) | AU2010210627B2 (xx) |
BR (1) | BRPI1008829A2 (xx) |
CA (1) | CA2751392C (xx) |
CL (1) | CL2011001855A1 (xx) |
CO (1) | CO6620071A2 (xx) |
CR (1) | CR20110464A (xx) |
CU (1) | CU24089B1 (xx) |
DO (1) | DOP2011000251A (xx) |
EC (1) | ECSP11011285A (xx) |
ES (1) | ES2734724T3 (xx) |
IL (1) | IL214401B (xx) |
MA (1) | MA33092B1 (xx) |
MX (2) | MX2011008093A (xx) |
MY (1) | MY156354A (xx) |
NZ (3) | NZ620458A (xx) |
PE (1) | PE20120585A1 (xx) |
PH (1) | PH12014500092A1 (xx) |
RU (2) | RU2655928C1 (xx) |
SG (2) | SG10201500207QA (xx) |
TN (1) | TN2011000381A1 (xx) |
UA (1) | UA114068C2 (xx) |
WO (1) | WO2010091131A1 (xx) |
ZA (2) | ZA201106412B (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
MX2011003820A (es) | 2008-10-10 | 2011-06-16 | Trius Therapeutics | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
SG10201500207QA (en) | 2009-02-03 | 2015-03-30 | Merck Sharp & Dohme | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
US8461188B2 (en) | 2011-10-20 | 2013-06-11 | Trius Therapeutics, Inc. | Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use |
WO2015054246A1 (en) * | 2013-10-07 | 2015-04-16 | Trius Therapeutics, Inc. | Methods of treating subjects with renal impairment using tedizolid |
CN105229001B (zh) * | 2014-04-18 | 2017-04-26 | 杭州普晒医药科技有限公司 | 一种噁唑烷酮类抗生素的晶型及制备方法、组合物和用途 |
WO2016009401A2 (en) * | 2014-07-18 | 2016-01-21 | Dr. Reddy's Laboratories Limited | Preparation of tedizolid phosphate |
CN104327119A (zh) * | 2014-10-17 | 2015-02-04 | 苏州明锐医药科技有限公司 | 磷酸泰地唑胺的制备方法 |
WO2016063246A1 (en) * | 2014-10-22 | 2016-04-28 | Sun Pharmaceutical Industries Limited | Crystalline form r of tedizolid phosphate |
WO2016088101A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088100A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
WO2016088102A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
CZ306245B6 (cs) * | 2014-12-11 | 2016-10-26 | Univerzita Karlova v Praze Farmaceutická fakulta v Hradci Králové | Substituovaný fenyltetrazol, jeho použití a farmaceutický přípravek ho obsahující |
CN104558034A (zh) * | 2015-01-21 | 2015-04-29 | 齐鲁制药有限公司 | 磷酸特地唑胺二钠盐的新晶型及其制备方法 |
CN105837634B (zh) * | 2015-01-30 | 2020-09-04 | 上海创诺制药有限公司 | 一种泰地唑胺磷酸酯结晶体及其制备方法 |
CN104592218B (zh) * | 2015-02-13 | 2015-11-04 | 江苏欧信医药化工有限公司 | 一种泰地唑胺的合成方法 |
CN106146485B (zh) * | 2015-04-01 | 2021-04-30 | 上海迪赛诺化学制药有限公司 | 一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体 |
CN106146558A (zh) * | 2015-04-10 | 2016-11-23 | 博瑞生物医药(苏州)股份有限公司 | 新的噁唑烷酮类化合物及其制备方法 |
CN106317114B (zh) * | 2015-07-02 | 2018-11-20 | 南京优科制药有限公司 | 一种磷酸特地唑胺的制备方法 |
CN105085570B (zh) * | 2015-09-12 | 2017-11-28 | 山东罗欣药业集团股份有限公司 | 一种磷酸特地唑胺化合物及其制备方法 |
CN105287407B (zh) * | 2015-11-24 | 2018-09-21 | 南京正大天晴制药有限公司 | 一种注射用磷酸特地唑胺 |
CN107121503B (zh) * | 2017-03-14 | 2020-04-28 | 南京优科制药有限公司 | 一种磷酸特地唑胺及其有关物质的分析方法 |
CN108948079A (zh) * | 2017-05-17 | 2018-12-07 | 上海奥博生物医药技术有限公司 | 一种特地唑胺二铵盐及晶型与其制备方法 |
WO2019118311A1 (en) * | 2017-12-13 | 2019-06-20 | Merck Sharp & Dohme Corp. | Pharmaceutical compositions of tedizolid phosphate |
MX2022016063A (es) | 2020-06-18 | 2023-04-11 | Akagera Medicines Inc | Compuestos de oxazolidinona, composiciones de liposomas que comprenden compuestos de oxazolidinona y metodos de uso de los mismos. |
CN112957332B (zh) * | 2021-02-04 | 2023-04-25 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其质量标准 |
CN112957333B (zh) * | 2021-02-05 | 2022-11-22 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其制备方法 |
CN113197874B (zh) * | 2021-04-28 | 2023-05-26 | 北京福元医药股份有限公司 | 一种磷酸特地唑胺口服固体制剂 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005058886A1 (en) * | 2003-12-18 | 2005-06-30 | Dong-A Pharm.Co.,Ltd. | Novel oxazolidinone derivatives |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU80081A1 (fr) | 1977-08-26 | 1979-05-15 | Delalande Sa | Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique |
US4128654A (en) | 1978-02-10 | 1978-12-05 | E. I. Du Pont De Nemours And Company | 5-Halomethyl-3-phenyl-2-oxazolidinones |
US4340606A (en) | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
FR2500450A1 (fr) | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
US4461773A (en) | 1982-09-15 | 1984-07-24 | E. I. Dupont De Nemours And Company | P-Oxooxazolidinylbenzene compounds as antibacterial agents |
CA1320730C (en) | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
US5254577A (en) | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
US4948801A (en) | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
US5144911A (en) * | 1990-11-28 | 1992-09-08 | Moore Cheri L | Component bed system for a pet |
AU667198B2 (en) | 1991-11-01 | 1996-03-14 | Pharmacia & Upjohn Company | Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents |
SK283420B6 (sk) | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
ATE161833T1 (de) | 1992-12-08 | 1998-01-15 | Upjohn Co | Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel |
US5688792A (en) | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
ATE182142T1 (de) | 1993-11-22 | 1999-07-15 | Upjohn Co | Substituierte hydroxyacetyl piperazine phenyl oxazolidinonsäureester |
GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
US6413981B1 (en) | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
EP1289984A4 (en) | 2000-06-05 | 2004-11-24 | Dong A Pharm Co Ltd | NEW OXAZOLIDE DERIVATIVES AND A METHOD FOR THEIR PRODUCTION |
US20020115669A1 (en) | 2000-08-31 | 2002-08-22 | Wiedeman Paul E. | Oxazolidinone chemotherapeutic agents |
YU52403A (sh) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
JP2004531518A (ja) | 2001-04-07 | 2004-10-14 | アストラゼネカ アクチボラグ | スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン |
US6623140B2 (en) | 2001-04-13 | 2003-09-23 | Scott R. Watterson | Illumination device having multiple light sources |
US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
KR20040044886A (ko) | 2001-09-11 | 2004-05-31 | 아스트라제네카 아베 | 항균제로서의 옥사졸리디논 및(또는) 이속사졸린 |
GB2396350A (en) | 2001-10-25 | 2004-06-23 | Astrazeneca Ab | Aryl substituted oxazolidinones with antibacterial activity |
NZ515881A (en) | 2001-12-03 | 2004-09-24 | New Zealand Dairy Board | Cheese flavour ingredient and method of its production |
AR038536A1 (es) | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
IL163688A0 (en) | 2002-02-28 | 2005-12-18 | Astrazeneca Ab | 3-Cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and theiruse as antibacterial agents |
BR0308018A (pt) | 2002-02-28 | 2005-01-04 | Astrazeneca Ab | Composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo, pró-droga, método para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hirolisável in vivo, composição farmacêutica, e, processo para a preparação de um composto ou um seu sal farmaceuticamente aceitável ou um seu éster hidrolisável in vivo |
WO2004048392A1 (en) | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinone and / or isoxazoline derivatives as antibacterial agents |
WO2004048350A2 (en) | 2002-11-28 | 2004-06-10 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
TW200500360A (en) | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
GB0306358D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
CA2529293A1 (en) | 2003-07-02 | 2005-01-20 | Merck & Co., Inc. | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
JP4607107B2 (ja) | 2003-07-02 | 2011-01-05 | メルク・シャープ・エンド・ドーム・コーポレイション | シクロプロピル基置換されたオキサゾリジノン抗生物質およびこれらの誘導体 |
NZ529860A (en) | 2003-11-28 | 2006-10-27 | Ovita Ltd | Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases |
WO2005051933A1 (en) | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
EP1713785A1 (en) | 2003-12-17 | 2006-10-25 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
US20080064689A1 (en) | 2004-05-25 | 2008-03-13 | Astrazeneca Ab | 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents |
GB0411596D0 (en) | 2004-05-25 | 2004-06-30 | Astrazeneca Ab | Chemical process |
JP2008500318A (ja) | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 抗菌剤としての3−{4−(ピリジン−3−イル)フェニル}−5−(1h−1,2,3−トリアゾール−1−イルメチル)−1,3−オキサゾリジン−2−オン |
US20070208062A1 (en) | 2004-05-25 | 2007-09-06 | Astrazeneca Ab | 3-(4-(2-dihydroisoxazol-3-ylpyridin-5-yl)phenyl)-5-triazol-1-ylmethyloxazolidin-2-one derivatives as mao inhibitors for the treatment of bacterial infections |
MXPA06013537A (es) | 2004-05-25 | 2007-01-26 | Astrazeneca Ab | 3-??4-{(alcanoil 6- substituidas) piridin-3-il}-3 -fenil!-5-(1h-1, 2, 3-triazol -1-ilmetil)-1, 3-oxazolidin- 2-onas como agentes antibacterianos. |
WO2006038100A1 (en) | 2004-10-08 | 2006-04-13 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
WO2007023507A2 (en) | 2005-06-20 | 2007-03-01 | Wockhardt Limited | Oxazolidinones bearing antimicrobial activity composition and methods of preparation |
WO2007138381A2 (en) | 2005-10-14 | 2007-12-06 | Targanta Therapeutics Inc. | Phosphonated oxazolidinones and uses thereof for the prevention and treatment of bone and joint infections |
JP5455906B2 (ja) * | 2007-08-06 | 2014-03-26 | ミクウルク ファーマシューティカルズ,インコーポレイテッド | 細菌感染症治療のための抗微生物性オルト−フルオロフェニルオキサゾリジノン |
CN101220001A (zh) * | 2008-01-25 | 2008-07-16 | 浙江博泰化工有限公司 | 一种利奈唑酮的合成方法 |
MX2011003820A (es) | 2008-10-10 | 2011-06-16 | Trius Therapeutics | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
SG10201500207QA (en) | 2009-02-03 | 2015-03-30 | Merck Sharp & Dohme | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
-
2010
- 2010-02-03 SG SG10201500207QA patent/SG10201500207QA/en unknown
- 2010-02-03 NZ NZ620458A patent/NZ620458A/en unknown
- 2010-02-03 CU CU2011000155A patent/CU24089B1/es active IP Right Grant
- 2010-02-03 PE PE2011001433A patent/PE20120585A1/es active IP Right Grant
- 2010-02-03 CN CN2010800143630A patent/CN102439006A/zh active Pending
- 2010-02-03 US US12/699,864 patent/US8426389B2/en active Active
- 2010-02-03 AU AU2010210627A patent/AU2010210627B2/en active Active
- 2010-02-03 CN CN201710063034.9A patent/CN107082790A/zh active Pending
- 2010-02-03 MY MYPI2011003576A patent/MY156354A/en unknown
- 2010-02-03 MX MX2011008093A patent/MX2011008093A/es not_active Application Discontinuation
- 2010-02-03 RU RU2016100418A patent/RU2655928C1/ru active
- 2010-02-03 UA UAA201110617A patent/UA114068C2/uk unknown
- 2010-02-03 JP JP2011549242A patent/JP5584705B2/ja active Active
- 2010-02-03 CA CA2751392A patent/CA2751392C/en active Active
- 2010-02-03 MA MA34136A patent/MA33092B1/fr unknown
- 2010-02-03 AP AP2011005835A patent/AP2987A/xx active
- 2010-02-03 RU RU2011136537/04A patent/RU2011136537A/ru not_active Application Discontinuation
- 2010-02-03 KR KR1020177034181A patent/KR101918678B1/ko active IP Right Grant
- 2010-02-03 NZ NZ594408A patent/NZ594408A/en active IP Right Revival
- 2010-02-03 WO PCT/US2010/023122 patent/WO2010091131A1/en active Application Filing
- 2010-02-03 NZ NZ712289A patent/NZ712289A/en unknown
- 2010-02-03 ES ES10703403T patent/ES2734724T3/es active Active
- 2010-02-03 KR KR1020177008992A patent/KR20170040371A/ko not_active Application Discontinuation
- 2010-02-03 EP EP10703403.5A patent/EP2393808B1/en active Active
- 2010-02-03 SG SG2011055456A patent/SG173497A1/en unknown
- 2010-02-03 KR KR1020117020614A patent/KR101739923B1/ko active IP Right Grant
- 2010-02-03 BR BRPI1008829A patent/BRPI1008829A2/pt not_active Application Discontinuation
-
2011
- 2011-08-01 DO DO2011000251A patent/DOP2011000251A/es unknown
- 2011-08-01 MX MX2020011773A patent/MX2020011773A/es unknown
- 2011-08-02 IL IL214401A patent/IL214401B/en active IP Right Grant
- 2011-08-02 CL CL2011001855A patent/CL2011001855A1/es unknown
- 2011-08-02 CO CO11097215A patent/CO6620071A2/es not_active Application Discontinuation
- 2011-08-03 TN TN2011000381A patent/TN2011000381A1/fr unknown
- 2011-08-23 EC EC2011011285A patent/ECSP11011285A/es unknown
- 2011-08-30 CR CR20110464A patent/CR20110464A/es unknown
- 2011-09-01 ZA ZA2011/06412A patent/ZA201106412B/en unknown
-
2013
- 2013-04-22 US US13/867,951 patent/US20130310343A1/en not_active Abandoned
- 2013-08-30 ZA ZA2013/06536A patent/ZA201306536B/en unknown
-
2014
- 2014-01-10 PH PH12014500092A patent/PH12014500092A1/en unknown
-
2015
- 2015-12-04 US US14/959,412 patent/US9624250B2/en active Active
-
2017
- 2017-03-10 US US15/455,463 patent/US9988406B2/en active Active
-
2018
- 2018-05-03 US US15/970,486 patent/US10442829B2/en active Active
- 2018-05-03 US US15/970,492 patent/US10065947B1/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005058886A1 (en) * | 2003-12-18 | 2005-06-30 | Dong-A Pharm.Co.,Ltd. | Novel oxazolidinone derivatives |
Non-Patent Citations (1)
Title |
---|
Vera-Cabrera, Lucio, et al. * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP2987A (en) | Crystalline form of (R)-3-(-4(2-(2-methyltetrazol-5-YL)pyridin-5-YL)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogen phosphate | |
HRP20181695T1 (hr) | Kristalni oblik inhibitora benzilbenzena sglt2 | |
EP2464736A4 (en) | PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL | |
EP2531225A4 (en) | METHOD FOR USE OF WATER-SOLUBLE INORGANIC COMPOUNDS FOR IMPLANTS | |
ZA201100243B (en) | Calcium salts of phosphorous acid for increasing the effect of fungicides | |
EP2766301A4 (en) | DRAINING PHOSPHATE PRECIPITATES | |
EP2698347A4 (en) | PROCESS FOR THE PRODUCTION OF LITHIUM PHOSPHATE AND IRON | |
SI2603509T1 (sl) | Kristalinična oblika spojine PIRIMIDIO(6,1-A) IZOKINOLIN-4-ENA | |
IL216109A0 (en) | Production of ammonium phosphates | |
PL2448945T3 (pl) | Krystaliczne postacie soli prasugrelu | |
IL216202A0 (en) | PROCESS FOR THE PREPARATION OF A COMPOUND USEFUL AS AN INHIBITOR OF TAFIa | |
ZA201105124B (en) | Process for the preparation of rosuvastatin salts | |
WO2010146348A3 (en) | Crystalline form of pemirolast | |
EP2476408A4 (en) | EXTERNAL PREPARATION CONTAINING AN ESTERPHOSPHORIC PANTETHINE | |
HUP1000638A2 (en) | Process for preparation of rosuvastatin salts | |
IL223584A0 (en) | Crystalline form of a 3-phenoxymethylpyrrolidine compounds | |
PL2665734T3 (pl) | Sposób wytwarzania związków zawierających grupę alfa-oksyfosforową | |
PL2689039T3 (pl) | Sposób krystalizacji związku rozpuszczalnego w wodzie | |
PL2435448T3 (pl) | Sposób wytwarzania dialkilofosforynów | |
EP2576438A4 (en) | Encapsulation of Phosphoric Pentasulfide | |
EP2593464A4 (en) | PROCESS FOR PREPARING A BIPHENYL-4-YL DIPHENYL PHOSPHATE COMPOSITION | |
PL389981A1 (pl) | Sposób otrzymywania związków fosforoorganicznych | |
GB0909238D0 (en) | Method for manufacturing lithium iron phosphate | |
GB0917078D0 (en) | Method for manufacturing lithium iron phosphate | |
PL388725A1 (pl) | Sposób wytwarzania monohydratu soli monosodowej kwasu [1-hydroksy-3-(N-mentylopentyloamino) propylideno]bisfosfonowego |