JP2011520847A - 遅効型ｙ２及び／又はｙ４レセプターアゴニスト - Google Patents

遅効型ｙ２及び／又はｙ４レセプターアゴニスト Download PDF

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Publication number
JP2011520847A
JP2011520847A JP2011508945A JP2011508945A JP2011520847A JP 2011520847 A JP2011520847 A JP 2011520847A JP 2011508945 A JP2011508945 A JP 2011508945A JP 2011508945 A JP2011508945 A JP 2011508945A JP 2011520847 A JP2011520847 A JP 2011520847A
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Japan
Prior art keywords
ethoxy
xaa
seq
acetyl
acid
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JP2011508945A
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Japanese (ja)
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JP2011520847A5 (enExample
Inventor
ソーレン オステルガール，
サンネ モラー クヌドセン，
ジェーン スペツラー，
ラスムス ヨルゲンセン，
ヤコブ コフォエド，
Original Assignee
ノボ・ノルデイスク・エー／エス
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Publication of JP2011520847A publication Critical patent/JP2011520847A/ja
Publication of JP2011520847A5 publication Critical patent/JP2011520847A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011508945A 2008-05-16 2009-05-18 遅効型ｙ２及び／又はｙ４レセプターアゴニスト Withdrawn JP2011520847A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP08156360 2008-05-16
EP08156360.3 2008-05-16
EP09154461.9 2009-03-05
EP09154461 2009-03-05
PCT/EP2009/055989 WO2009138511A1 (en) 2008-05-16 2009-05-18 Long-acting y2 and/or y4 receptor agonists

Publications (2)

Publication Number Publication Date
JP2011520847A true JP2011520847A (ja) 2011-07-21
JP2011520847A5 JP2011520847A5 (enExample) 2012-07-05

Family

ID=40934036

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011508945A Withdrawn JP2011520847A (ja) 2008-05-16 2009-05-18 遅効型ｙ２及び／又はｙ４レセプターアゴニスト

Country Status (12)

Country Link
US (1) US20110275559A1 (enExample)
EP (1) EP2279204A1 (enExample)
JP (1) JP2011520847A (enExample)
KR (1) KR20110017874A (enExample)
CN (1) CN102027007A (enExample)
AU (1) AU2009248041B2 (enExample)
BR (1) BRPI0912615A2 (enExample)
CA (1) CA2723855A1 (enExample)
IL (1) IL208836A0 (enExample)
MX (1) MX2010011845A (enExample)
RU (1) RU2504550C2 (enExample)
WO (1) WO2009138511A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022506070A (ja) * 2018-11-01 2022-01-17 イーライ リリー アンド カンパニー タンパク質チロシン－チロシン類縁体およびそれを使用する方法
JP2023522081A (ja) * 2020-04-17 2023-05-26 アイツーオー・セラピューティクス・インコーポレイテッド 長時間作用型ペプチドチロシンチロシン（ｐｙｙ）類似体及び使用方法

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2450374B9 (en) 2009-07-02 2016-11-23 Takeda Pharmaceutical Company Limited Peptide and use thereof
JP2013505221A (ja) * 2009-09-18 2013-02-14 ノヴォ ノルディスク アー／エス 長時間作用性ｙ２受容体アゴニスト
WO2011058165A1 (en) * 2009-11-13 2011-05-19 Novo Nordisk A/S Long-acting y2 receptor agonists
GB201001333D0 (en) * 2010-01-27 2010-03-17 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
EP2600887A4 (en) 2010-07-09 2014-01-22 Amylin Pharmaceuticals Llc MICROCRYSTALLINE Y RECEPTOR AGONISTS
RU2600440C3 (ru) 2010-12-16 2021-12-10 Ново Нордиск А/С Твердые композиции, содержащие агонист glp-1 и соль n-(8-(2-гидроксибензоил)амино)каприловой кислоты
US10933120B2 (en) 2012-03-22 2021-03-02 Novo Nordisk A/S Compositions of GLP-1 peptides and preparation thereof
AU2014261336B2 (en) 2013-05-02 2019-02-28 Novo Nordisk A/S Oral dosing of GLP-1 compounds
EP2842965A1 (en) 2013-09-03 2015-03-04 Gubra ApS Neuromedin U analogs comprising serum albumin binding amino acid residue
WO2015073878A1 (en) * 2013-11-15 2015-05-21 Ur Diet, Llc Real-time satiety biofeedback
HRP20191036T1 (hr) * 2013-11-15 2019-09-06 Novo Nordisk A/S Selektivni spojevi pyy i njihova upotreba
US9085637B2 (en) 2013-11-15 2015-07-21 Novo Nordisk A/S Selective PYY compounds and uses thereof
US10583172B2 (en) 2013-11-15 2020-03-10 Novo Nordisk A/S HPYY(1-36) having a beta-homoarginine substitution at position 35
EP3094391B1 (en) 2014-01-17 2024-11-20 Repligen Corporation Sterilizing chromatography columns
US20240100450A9 (en) * 2014-01-17 2024-03-28 Repligen Corporation Sterilizing chromatography columns
CN111620940A (zh) * 2014-05-21 2020-09-04 哈佛大学的校长及成员们 Ras抑制肽和其用途
TWI694082B (zh) * 2015-06-12 2020-05-21 丹麥商諾佛 儂迪克股份有限公司 選擇性ｐｙｙ化合物及其用途
BR112020014624A2 (pt) 2018-02-02 2020-12-08 Novo Nordisk A/S Composições sólidas compreendendo agonista de glp-1, sal de ácido n-(8-(2-hidroxibenzoil) amino)caprílico e lubrificante
GB201908426D0 (en) * 2019-06-12 2019-07-24 Imp College Innovations Ltd Appetite suppressing compounds
CA3215858A1 (en) 2021-04-27 2022-11-03 Zhenhuan ZHENG Combination of bitter receptor agonist and gut-signaling compound

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007505840A (ja) * 2003-09-19 2007-03-15 ノボ　ノルディスク　アクティーゼルスカブ 新規ｇｌｐ−１誘導体
JP2007529463A (ja) * 2004-03-17 2007-10-25 ７ティーエム ファーマ エイ／エス 治療的介入のためのｙ４選択性レセプターアゴニスト
JP2007531711A (ja) * 2004-02-11 2007-11-08 アミリン・ファーマシューティカルズ，インコーポレイテッド 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
JP2008507477A (ja) * 2004-07-08 2008-03-13 ノボ　ノルディスク　アクティーゼルスカブ ポリペプチド延長タグ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2275207C2 (ru) * 2000-12-14 2006-04-27 Амилин Фармасьютикалз, Инк. Способ снижения доступности питательного вещества, способ подавления аппетита
WO2007009894A2 (en) * 2005-07-18 2007-01-25 Novo Nordisk A/S Peptides for use in the treatment of obesity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007505840A (ja) * 2003-09-19 2007-03-15 ノボ　ノルディスク　アクティーゼルスカブ 新規ｇｌｐ−１誘導体
JP2007531711A (ja) * 2004-02-11 2007-11-08 アミリン・ファーマシューティカルズ，インコーポレイテッド 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
JP2007529463A (ja) * 2004-03-17 2007-10-25 ７ティーエム ファーマ エイ／エス 治療的介入のためのｙ４選択性レセプターアゴニスト
JP2008507477A (ja) * 2004-07-08 2008-03-13 ノボ　ノルディスク　アクティーゼルスカブ ポリペプチド延長タグ

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022506070A (ja) * 2018-11-01 2022-01-17 イーライ リリー アンド カンパニー タンパク質チロシン－チロシン類縁体およびそれを使用する方法
JP7280949B2 (ja) 2018-11-01 2023-05-24 イーライ リリー アンド カンパニー タンパク質チロシン－チロシン類縁体およびそれを使用する方法
JP2023082013A (ja) * 2018-11-01 2023-06-13 イーライ リリー アンド カンパニー タンパク質チロシン－チロシン類縁体およびそれを使用する方法
JP2023522081A (ja) * 2020-04-17 2023-05-26 アイツーオー・セラピューティクス・インコーポレイテッド 長時間作用型ペプチドチロシンチロシン（ｐｙｙ）類似体及び使用方法

Also Published As

Publication number Publication date
IL208836A0 (en) 2011-01-31
US20110275559A1 (en) 2011-11-10
RU2504550C2 (ru) 2014-01-20
AU2009248041A1 (en) 2009-11-19
MX2010011845A (es) 2010-11-22
CN102027007A (zh) 2011-04-20
WO2009138511A1 (en) 2009-11-19
EP2279204A1 (en) 2011-02-02
BRPI0912615A2 (pt) 2016-01-26
CA2723855A1 (en) 2009-11-19
KR20110017874A (ko) 2011-02-22
AU2009248041B2 (en) 2013-10-03
RU2010149474A (ru) 2012-06-27

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