|
US5380758A
(en)
|
1991-03-29 |
1995-01-10 |
Brigham And Women's Hospital |
S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
|
|
US5703073A
(en)
*
|
1995-04-19 |
1997-12-30 |
Nitromed, Inc. |
Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
|
|
KR100384979B1
(ko)
|
1995-09-07 |
2003-10-17 |
에프. 호프만-라 로슈 아게 |
심부전증및신부전증치료용의신규한4-(옥시알콕시페닐)-3-옥시-피페리딘
|
|
US5994294A
(en)
|
1996-02-02 |
1999-11-30 |
Nitromed, Inc. |
Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
|
|
JP2001504457A
(ja)
|
1996-11-01 |
2001-04-03 |
ニトロメド インコーポレーテッド |
ニトロソ化およびニトロシル化ホスホジエステラーゼ阻害剤化合物、組成物及びその使用法
|
|
IT1295694B1
(it)
|
1996-11-14 |
1999-05-27 |
Nicox Sa |
Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
|
|
IT1292426B1
(it)
*
|
1997-06-27 |
1999-02-08 |
Nicox Sa |
Sali nitrati di ace-inibitori
|
|
HU230302B1
(hu)
|
2000-10-20 |
2015-12-28 |
Eisai R&D Management Co., Ltd. |
Nitrogéntartalmú aromás származékok és ezeket tartalmazó gyógyászati készítmények
|
|
AU2003233963B2
(en)
|
2002-04-29 |
2008-09-11 |
Actelion Pharmaceuticals Ltd |
7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases
|
|
BR0312000A
(pt)
|
2002-06-27 |
2005-03-22 |
Actelion Pharmaceuticals Ltd |
Compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, uso dos compostos
|
|
US20040204455A1
(en)
|
2003-04-10 |
2004-10-14 |
Cody Wayne Livingston |
Piperidine derivative rennin inhibitors
|
|
AU2004234040A1
(en)
|
2003-04-28 |
2004-11-11 |
Actelion Pharmaceuticals Ltd |
Diazabicyclononene and tetrahydropyridine derivatives as renin inhibitors
|
|
BRPI0409881A
(pt)
|
2003-04-29 |
2006-05-23 |
Actelion Pharmaceuticals Ltd |
compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, usos de compostos e de um ou mais compostos em combinação com outros compostos farmacologicamente ativos
|
|
RU2005137174A
(ru)
|
2003-04-30 |
2006-03-27 |
Актелион Фармасьютикалз Лтд. (Ch) |
Азабициклононеновые производные
|
|
WO2004096799A1
(en)
|
2003-04-30 |
2004-11-11 |
Actelion Pharmaceuticals Ltd |
Tropane derivatives and their use as ace inhibitors
|
|
EP1622685A1
(en)
|
2003-04-30 |
2006-02-08 |
Actelion Pharmaceuticals Ltd. |
9-azabicyclo[3.3.1]non-6-ene derivatives with a heteroatom at the 3-position as renin inhibitors
|
|
KR20060015573A
(ko)
|
2003-05-02 |
2006-02-17 |
액테리온 파마슈티칼 리미티드 |
신규한 디아자비시클로노넨 유도체
|
|
TW200513461A
(en)
|
2003-10-01 |
2005-04-16 |
Speedel Experimenta Ag |
Organische verbindungen
|
|
WO2005040120A1
(en)
|
2003-10-09 |
2005-05-06 |
Actelion Pharmaceuticals Ltd |
Tetrahydropyridine derivatives
|
|
JP2007508262A
(ja)
|
2003-10-13 |
2007-04-05 |
アクテリオン ファマシューティカルズ リミテッド |
新規ジアザビシクロノネン誘導体およびその使用
|
|
JP2007509099A
(ja)
|
2003-10-23 |
2007-04-12 |
アクテリオン ファマシューティカルズ リミテッド |
新規ジアザビシクロノネンおよび新規極性側鎖を有するテトラヒドロピリジン誘導体
|
|
AU2004295092A1
(en)
|
2003-12-05 |
2005-06-16 |
Actelion Pharmaceuticals Ltd. |
Azabicyclooctene and other tetrahydropyridine derivatives with a new side-chain
|
|
WO2005054243A1
(en)
|
2003-12-05 |
2005-06-16 |
Actelion Pharmaceuticals Ltd |
Diazabicyclononene derivatives and their use as renin inhibitors
|
|
AR053406A1
(es)
*
|
2004-07-09 |
2007-05-09 |
Speedel Experimenta Ag |
Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas
|
|
WO2006021399A2
(en)
|
2004-08-25 |
2006-03-02 |
Actelion Pharmaceuticals Ltd |
Azabicyclononene derivatives as renin inhibitors
|
|
ATE462703T1
(de)
|
2004-08-25 |
2010-04-15 |
Actelion Pharmaceuticals Ltd |
Bicyclononen-derivate als renin-inhibitoren
|
|
WO2006021403A1
(en)
|
2004-08-25 |
2006-03-02 |
Actelion Pharmaceuticals Ltd |
Bicyclononene derivatives
|
|
WO2006021401A2
(en)
|
2004-08-25 |
2006-03-02 |
Actelion Pharmaceuticals Ltd |
Bicylononene derivatives
|
|
WO2006058546A1
(en)
|
2004-12-01 |
2006-06-08 |
Actelion Pharmaceuticals Ltd |
Novel lactame derivatives as renin inhibitors
|
|
AR052263A1
(es)
|
2004-12-08 |
2007-03-07 |
Actelion Pharmaceuticals Ltd |
Derivado de diazabiciclononeno
|
|
WO2006063610A1
(en)
|
2004-12-17 |
2006-06-22 |
Actelion Pharmaceuticals Ltd |
Heteroaryl substituted diazabicyclononene derivatives
|
|
GB0428526D0
(en)
|
2004-12-30 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
GB0500784D0
(en)
*
|
2005-01-14 |
2005-02-23 |
Novartis Ag |
Organic compounds
|
|
ATE514697T1
(de)
|
2005-01-28 |
2011-07-15 |
Actelion Pharmaceuticals Ltd |
7-ä4-ä2-(2,6-dichloro-4- methylphenoxy)ethoxyüphenylü-3,9- diazabicycloä3.3.1ünon-6-ene-6-carbonsäure- cyclopropyl-(2,3-dimethylbenzyl)amid als renin- hemmer für die behandlung von bluthochdruck
|
|
WO2006092268A1
(en)
|
2005-03-02 |
2006-09-08 |
Actelion Pharmaceuticals Ltd |
Bicyclic five-membered heteroaryl derivatives and their use as renin inhibitors
|
|
GB0504850D0
(en)
*
|
2005-03-09 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
|
EP1863763A1
(en)
|
2005-03-31 |
2007-12-12 |
Speedel Experimenta AG |
3,4,5-substituted piperidines as renin inhibitors
|
|
TW200716622A
(en)
|
2005-03-31 |
2007-05-01 |
Speedel Experimenta Ag |
Substituted piperidines
|
|
GB0510810D0
(en)
|
2005-05-26 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
|
BRPI0609890A2
(pt)
|
2005-05-27 |
2010-05-04 |
Actelion Pharmaceuticals Ltd |
composto, composição farmacêutica, e, uso de um composto
|
|
GB0511063D0
(en)
|
2005-05-31 |
2005-07-06 |
Novartis Ag |
Organic compounds
|
|
WO2006131884A2
(en)
|
2005-06-07 |
2006-12-14 |
Actelion Pharmaceuticals Ltd |
Thiazole substituted diazabicyclononane or-nonene derivatives as renin inhibitors
|
|
CA2615048A1
(en)
|
2005-07-22 |
2007-01-25 |
Merck Frosst Canada Ltd. |
Renin inhibitors
|
|
WO2007034406A1
(en)
|
2005-09-22 |
2007-03-29 |
Actelion Pharmaceuticals Ltd |
Pyrrolidine-3-carboxylic acid amide derivatives and their use as inhibitors of renin
|
|
WO2007034445A2
(en)
|
2005-09-26 |
2007-03-29 |
Actelion Pharmaceuticals Ltd |
Novel piperazine derivatives as renin inhibitors for cardiovascular events and renal insufficiency
|
|
WO2007049224A1
(en)
|
2005-10-25 |
2007-05-03 |
Actelion Pharmaceuticals Ltd |
Novel hexahydro- or octahydro-cyclopenta[c]pyrrole derivatives
|
|
PT2420491E
(pt)
|
2005-12-30 |
2013-10-14 |
Novartis Ag |
Compostos de piperidina 3,5-substituída como inibidores de renina
|
|
EP1816122A3
(en)
*
|
2006-01-19 |
2007-09-19 |
Speedel Experimenta AG |
3,4,5-substituted piperidines as therapeutic compounds
|
|
RU2425032C2
(ru)
|
2006-02-02 |
2011-07-27 |
Актелион Фармасьютикалз Лтд |
Вторичные амины в качестве ингибиторов ренина
|
|
BRPI0708487A2
(pt)
|
2006-03-03 |
2011-05-31 |
Actelion Pharmaceuticals Ltd |
composto, composição farmacêutica que o compreende e seu uso
|
|
CL2007000595A1
(es)
|
2006-03-08 |
2008-01-04 |
Actelion Pharmaceuticals Ltd |
Compuestos derivados de piperidina; composicion farmaceutica y uso para el tratamiento y/o profilaxis de enfermedades seleccionadas entre hipertension, insuficiencia cardiaca congestiva e insuficiencia renal entre otras.
|
|
EP2081927B1
(en)
|
2006-09-18 |
2011-08-17 |
Vitae Pharmaceuticals, Inc. |
Piperidine derivatives as renin inhibitors
|
|
DE602007007664D1
(de)
*
|
2006-11-17 |
2010-08-19 |
Merck Frosst Canada Inc |
Renininhibitoren
|
|
US8343968B2
(en)
*
|
2007-05-24 |
2013-01-01 |
Merck Canada Inc. |
Case of renin inhibitors
|
|
US20110207783A1
(en)
|
2007-08-07 |
2011-08-25 |
Daniel Dube |
Renin inhibitors
|
|
CA2707565A1
(en)
*
|
2007-12-04 |
2009-06-11 |
Merck Frosst Canada Ltd. |
Renin inhibitors
|
|
JP2011520924A
(ja)
|
2008-05-22 |
2011-07-21 |
メルク フロスト カナダ リミテツド |
レニン阻害剤としての3,4−置換ピペリジン誘導体
|
|
WO2011020193A1
(en)
|
2009-08-18 |
2011-02-24 |
Merck Frosst Canada Ltd. |
Renin inhibitors
|