JP2011511786A5 - - Google Patents
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- Publication number
- JP2011511786A5 JP2011511786A5 JP2010545576A JP2010545576A JP2011511786A5 JP 2011511786 A5 JP2011511786 A5 JP 2011511786A5 JP 2010545576 A JP2010545576 A JP 2010545576A JP 2010545576 A JP2010545576 A JP 2010545576A JP 2011511786 A5 JP2011511786 A5 JP 2011511786A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- composition
- treatment
- value
- degarelix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002966 serum Anatomy 0.000 claims 13
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 11
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 11
- 108010052004 acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide Proteins 0.000 claims 11
- MEUCPCLKGZSHTA-XYAYPHGZSA-N degarelix Chemical compound C([C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CC=1C=CC(NC(=O)[C@H]2NC(=O)NC(=O)C2)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(NC(N)=O)C=C1 MEUCPCLKGZSHTA-XYAYPHGZSA-N 0.000 claims 11
- 229960002272 degarelix Drugs 0.000 claims 11
- 238000012423 maintenance Methods 0.000 claims 5
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 4
- 208000010658 metastatic prostate carcinoma Diseases 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 230000007423 decrease Effects 0.000 claims 3
- 102000001554 Hemoglobins Human genes 0.000 claims 2
- 108010054147 Hemoglobins Proteins 0.000 claims 2
- 230000002250 progressing effect Effects 0.000 claims 2
- 229960003604 testosterone Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2774108P | 2008-02-11 | 2008-02-11 | |
| US61/027,741 | 2008-02-11 | ||
| EP08250703.9 | 2008-02-29 | ||
| EP08250703 | 2008-02-29 | ||
| US14795609P | 2009-01-28 | 2009-01-28 | |
| US61/147,956 | 2009-01-28 | ||
| PCT/IB2009/000370 WO2009101533A1 (en) | 2008-02-11 | 2009-02-10 | Treatment of metastatic stage prostate cancer with degarelix |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014087895A Division JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011511786A JP2011511786A (ja) | 2011-04-14 |
| JP2011511786A5 true JP2011511786A5 (enExample) | 2012-03-22 |
| JP5876652B2 JP5876652B2 (ja) | 2016-03-02 |
Family
ID=39718285
Family Applications (12)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545575A Active JP5924866B2 (ja) | 2008-02-11 | 2009-02-10 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2010545576A Active JP5876652B2 (ja) | 2008-02-11 | 2009-02-10 | 転移期前立腺癌を治療する方法 |
| JP2014051197A Active JP6189234B2 (ja) | 2008-02-11 | 2014-03-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014087895A Active JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
| JP2016095555A Pending JP2016193910A (ja) | 2008-02-11 | 2016-05-11 | 転移期前立腺癌を治療する方法 |
| JP2016099437A Pending JP2016216455A (ja) | 2008-02-11 | 2016-05-18 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2017185676A Active JP6618967B2 (ja) | 2008-02-11 | 2017-09-27 | 転移期前立腺癌を治療する方法 |
| JP2022109616A Active JP7400029B2 (ja) | 2008-02-11 | 2022-07-07 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2022142833A Pending JP2022184898A (ja) | 2008-02-11 | 2022-09-08 | 転移期前立腺癌を治療する方法 |
| JP2023206150A Pending JP2024028869A (ja) | 2008-02-11 | 2023-12-06 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2025106071A Pending JP2025160167A (ja) | 2008-02-11 | 2025-06-24 | 転移期前立腺癌を治療する方法 |
| JP2025194876A Pending JP2026027448A (ja) | 2008-02-11 | 2025-11-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545575A Active JP5924866B2 (ja) | 2008-02-11 | 2009-02-10 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
Family Applications After (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014051197A Active JP6189234B2 (ja) | 2008-02-11 | 2014-03-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2014087895A Active JP6254042B2 (ja) | 2008-02-11 | 2014-04-22 | 転移期前立腺癌を治療する方法 |
| JP2016095555A Pending JP2016193910A (ja) | 2008-02-11 | 2016-05-11 | 転移期前立腺癌を治療する方法 |
| JP2016099437A Pending JP2016216455A (ja) | 2008-02-11 | 2016-05-18 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2017185676A Active JP6618967B2 (ja) | 2008-02-11 | 2017-09-27 | 転移期前立腺癌を治療する方法 |
| JP2022109616A Active JP7400029B2 (ja) | 2008-02-11 | 2022-07-07 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2022142833A Pending JP2022184898A (ja) | 2008-02-11 | 2022-09-08 | 転移期前立腺癌を治療する方法 |
| JP2023206150A Pending JP2024028869A (ja) | 2008-02-11 | 2023-12-06 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
| JP2025106071A Pending JP2025160167A (ja) | 2008-02-11 | 2025-06-24 | 転移期前立腺癌を治療する方法 |
| JP2025194876A Pending JP2026027448A (ja) | 2008-02-11 | 2025-11-14 | Ｇｎｒｈアンタゴニストであるデガレリクスを用いる前立腺癌の治療方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (18) | US20090203623A1 (enExample) |
| EP (7) | EP2505204B1 (enExample) |
| JP (12) | JP5924866B2 (enExample) |
| KR (8) | KR20140130757A (enExample) |
| CN (4) | CN101939020B (enExample) |
| AU (2) | AU2009213748B9 (enExample) |
| BR (2) | BRPI0908129A2 (enExample) |
| CA (3) | CA2714444A1 (enExample) |
| CY (3) | CY1115561T1 (enExample) |
| DK (3) | DK2505204T3 (enExample) |
| EA (4) | EA036695B1 (enExample) |
| ES (3) | ES2540235T3 (enExample) |
| HK (1) | HK1198243A1 (enExample) |
| HR (3) | HRP20140665T1 (enExample) |
| IL (3) | IL207295A (enExample) |
| JO (1) | JOP20090061B1 (enExample) |
| MX (2) | MX2010008816A (enExample) |
| NZ (4) | NZ603958A (enExample) |
| PL (3) | PL2650012T3 (enExample) |
| PT (3) | PT2505204E (enExample) |
| RU (2) | RU2504393C2 (enExample) |
| SI (3) | SI2249859T1 (enExample) |
| TW (2) | TWI442932B (enExample) |
| WO (2) | WO2009101533A1 (enExample) |
| ZA (1) | ZA201005697B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| TWI442932B (zh) | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法 |
| JO3525B1 (ar) * | 2008-02-11 | 2020-07-05 | Ferring Int Center Sa | علاج سرطان البروستاتا في المرحلة النقيلية بدواء ديجاريليكس |
| KR101795643B1 (ko) * | 2009-05-01 | 2017-11-09 | 훼링 비.브이. | 전립선암 치료용 조성물 |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| FR2964323B1 (fr) * | 2010-09-08 | 2012-11-09 | Jean Pierre Raynaud | Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| WO2012055903A1 (en) | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| US10952415B2 (en) | 2011-03-09 | 2021-03-23 | Richard G. Pestell | Prostate cancer cell lines, gene signatures and uses thereof |
| CN102204889B (zh) * | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| HK1209673A1 (en) | 2012-05-14 | 2016-04-08 | Prostagene Llc | Using modulators of ccr5 for treating cancer |
| KR102140982B1 (ko) | 2012-06-01 | 2020-08-05 | 훼링 비.브이. | 데가렐릭스의 제조 방법 |
| WO2014052237A1 (en) | 2012-09-26 | 2014-04-03 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| SMT202200255T1 (it) | 2012-09-28 | 2022-07-21 | Takeda Pharmaceuticals Co | Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea |
| EP4223298A3 (en) | 2013-03-15 | 2023-08-16 | AbbVie Inc. | Compositions for use in treating heavy menstrual bleeding |
| WO2014186608A1 (en) * | 2013-05-15 | 2014-11-20 | Adverse Events, Inc. | System and method for surveillance and evaluation of safety risks associated with medical interventions |
| AU2015308987B2 (en) * | 2014-08-26 | 2021-02-18 | Kaass Discovery As | Methods, agents and compositions for treatment of inflammatory conditions |
| JP6941565B2 (ja) | 2015-05-12 | 2021-09-29 | ドレクセル ユニバーシティ | がん転移を処置または防止するのに有用な化合物および組成物、ならびにこれらの使用法 |
| SI3518932T1 (sl) | 2016-09-30 | 2025-03-31 | Takeda Pharmaceutical Company Limited | Zdravljenje raka prostate |
| JP6990717B2 (ja) * | 2017-01-30 | 2022-02-03 | アンテヴ リミテッド | 少なくとも１種のｇｎｒｈアンタゴニストを含む組成物 |
| KR20240096623A (ko) | 2017-10-16 | 2024-06-26 | 아라곤 파마슈티컬스, 인코포레이티드 | 비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐 |
| US11690854B2 (en) | 2018-04-19 | 2023-07-04 | Abbvie Inc. | Methods of treating heavy menstrual bleeding |
| CA3107597A1 (en) * | 2018-08-01 | 2020-02-06 | Abbvie Inc. | Dosing regimens for elagolix |
| RU2731002C1 (ru) * | 2019-10-22 | 2020-08-26 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ лечения рака предстательной железы |
| CN116407494B (zh) * | 2023-03-02 | 2024-07-09 | 山东大学齐鲁医院 | 一种醋酸地加瑞克注射液及其制备方法、用途 |
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| TWI442932B (zh) * | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法 |
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| EP2421887B1 (en) | 2009-04-24 | 2015-04-22 | Polypeptide Laboratories A/S | Method for the manufacture of degarelix |
| KR101795643B1 (ko) * | 2009-05-01 | 2017-11-09 | 훼링 비.브이. | 전립선암 치료용 조성물 |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2011066386A1 (en) | 2009-11-25 | 2011-06-03 | Novetide, Ltd. | Process for production of degarelix |
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| WO2012055903A1 (en) * | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN102204889B (zh) | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| EP2731607B1 (en) * | 2011-07-15 | 2017-10-11 | Ferring B.V. | Method for timing a colonoscopy wherein a picosulate composition is administered |
| KR102140982B1 (ko) | 2012-06-01 | 2020-08-05 | 훼링 비.브이. | 데가렐릭스의 제조 방법 |
-
2009
- 2009-02-09 TW TW098104075A patent/TWI442932B/zh active
- 2009-02-09 JO JOP/2009/0061A patent/JOP20090061B1/ar active
- 2009-02-09 TW TW098104073A patent/TWI539959B/zh active
- 2009-02-10 EA EA201300741A patent/EA036695B1/ru not_active IP Right Cessation
- 2009-02-10 CN CN200980104713XA patent/CN101939020B/zh not_active Ceased
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