JP2011509263A5 - - Google Patents

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Publication number
JP2011509263A5
JP2011509263A5 JP2010541680A JP2010541680A JP2011509263A5 JP 2011509263 A5 JP2011509263 A5 JP 2011509263A5 JP 2010541680 A JP2010541680 A JP 2010541680A JP 2010541680 A JP2010541680 A JP 2010541680A JP 2011509263 A5 JP2011509263 A5 JP 2011509263A5
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JP
Japan
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mixture
mmol
carboxylic acid
methyl
hydroxy
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JP2010541680A
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English (en)
Japanese (ja)
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JP2011509263A (ja
JP5441269B2 (ja
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Priority claimed from CNA2008100003466A external-priority patent/CN101481352A/zh
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Publication of JP2011509263A5 publication Critical patent/JP2011509263A5/ja
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JP2010541680A 2008-01-10 2009-01-04 ビシクロ置換ピラゾロン−アゾ誘導体、その調製プロセス及び製薬学的使用 Active JP5441269B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNA2008100003466A CN101481352A (zh) 2008-01-10 2008-01-10 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用
CN200810000346.6 2008-01-10
PCT/CN2009/000001 WO2009092276A1 (zh) 2008-01-10 2009-01-04 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用

Publications (3)

Publication Number Publication Date
JP2011509263A JP2011509263A (ja) 2011-03-24
JP2011509263A5 true JP2011509263A5 (https=) 2012-02-23
JP5441269B2 JP5441269B2 (ja) 2014-03-12

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ID=40878665

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010541680A Active JP5441269B2 (ja) 2008-01-10 2009-01-04 ビシクロ置換ピラゾロン−アゾ誘導体、その調製プロセス及び製薬学的使用

Country Status (15)

Country Link
US (2) US8367710B2 (https=)
EP (1) EP2236500B1 (https=)
JP (1) JP5441269B2 (https=)
KR (1) KR101556808B1 (https=)
CN (2) CN101481352A (https=)
AU (1) AU2009207966B2 (https=)
BR (1) BRPI0907234B1 (https=)
CA (1) CA2711535C (https=)
ES (1) ES2533366T3 (https=)
MX (1) MX2010007553A (https=)
PT (1) PT2236500E (https=)
RU (1) RU2488582C2 (https=)
UA (1) UA101172C2 (https=)
WO (1) WO2009092276A1 (https=)
ZA (1) ZA201004794B (https=)

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CN101921232A (zh) * 2009-06-11 2010-12-22 上海恒瑞医药有限公司 双环取代吡唑酮偶氮类衍生物的盐,其制备方法及其在医药上的应用
WO2011049213A1 (ja) * 2009-10-23 2011-04-28 日産化学工業株式会社 縮環へテロ環化合物及びトロンボポエチンレセプター活性化剤
CN103360317B (zh) * 2012-04-11 2016-12-14 齐鲁制药有限公司 双环取代吡唑酮偶氮类衍生物、其制备方法及用途
CN103724206A (zh) * 2014-01-17 2014-04-16 青岛农业大学 化合物2-溴-4-氟-6-硝基苯酚的制备方法和农用生物活性
WO2015111085A2 (en) * 2014-01-27 2015-07-30 Cadila Healthcare Limited Processes for the preparation of eltrombopag and pharmaceutically acceptable salts, solvates and intermediates thereof
US9849077B2 (en) 2014-03-10 2017-12-26 Mary Kay Inc. Skin lightening compositions
CN104592033A (zh) * 2014-12-30 2015-05-06 杭州和泽医药科技有限公司 一种艾曲波帕关键中间体的合成方法
RU2733844C2 (ru) * 2016-01-22 2020-10-07 Цзянсу Хэнжуй Медицин Ко., Лтд. Фармацевтическая композиция, включающая бициклозамещенное азопроизводное пиразолона или его соль, и способ их получения
CN106994120B (zh) * 2016-01-22 2021-05-14 江苏恒瑞医药股份有限公司 一种含有双环取代吡唑酮偶氮类衍生物或其盐的药物组合物及其制备方法
WO2018133818A1 (zh) * 2017-01-19 2018-07-26 江苏恒瑞医药股份有限公司 一种双环取代吡唑酮偶氮类衍生物的制备方法及其中间体
CN110028497B (zh) * 2018-01-11 2020-11-17 江苏恒瑞医药股份有限公司 一种血小板生成素模拟物的乙醇胺盐的结晶形式及制备方法
EP3909645A4 (en) * 2019-01-08 2022-07-27 Jiangsu Hengrui Medicine Co., Ltd. DOSING REGIME FOR A BICYCLIC SUBSTITUTE PYRAZOLONEAZOLE DERIVATIVE
CN112062699B (zh) * 2020-11-13 2021-02-26 苏州开元民生科技股份有限公司 一种邻氨基苯硫酚的制备方法
TW202302090A (zh) * 2021-04-30 2023-01-16 大陸商江蘇恒瑞醫藥股份有限公司 血小板生成素受體激動劑的給藥方案
US20250144077A1 (en) * 2022-01-25 2025-05-08 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Dosage regimen for thrombopoietin receptor agonist
WO2025140275A1 (zh) * 2023-12-25 2025-07-03 江苏恒瑞医药股份有限公司 取代吡唑啉偶氮衍生物的磷酸酯化合物或其可药用盐

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