JP2011237442A5 - - Google Patents
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- Publication number
- JP2011237442A5 JP2011237442A5 JP2011149985A JP2011149985A JP2011237442A5 JP 2011237442 A5 JP2011237442 A5 JP 2011237442A5 JP 2011149985 A JP2011149985 A JP 2011149985A JP 2011149985 A JP2011149985 A JP 2011149985A JP 2011237442 A5 JP2011237442 A5 JP 2011237442A5
- Authority
- JP
- Japan
- Prior art keywords
- insulin
- antibody
- property
- bound
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 26
- 229940125396 insulin Drugs 0.000 claims 17
- 102000004877 Insulin Human genes 0.000 claims 9
- 108090001061 Insulin Proteins 0.000 claims 9
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- 210000004408 hybridoma Anatomy 0.000 claims 2
- 108010076181 Proinsulin Proteins 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000002608 insulinlike Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011149985A JP5661572B2 (ja) | 2009-07-21 | 2011-07-06 | インスリン測定方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009170292 | 2009-07-21 | ||
| JP2009170292 | 2009-07-21 | ||
| JP2011149985A JP5661572B2 (ja) | 2009-07-21 | 2011-07-06 | インスリン測定方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010546566A Division JP4782249B2 (ja) | 2009-07-21 | 2010-07-21 | インスリン測定方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011237442A JP2011237442A (ja) | 2011-11-24 |
| JP2011237442A5 true JP2011237442A5 (enExample) | 2014-05-22 |
| JP5661572B2 JP5661572B2 (ja) | 2015-01-28 |
Family
ID=43499145
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010546566A Expired - Fee Related JP4782249B2 (ja) | 2009-07-21 | 2010-07-21 | インスリン測定方法 |
| JP2011149985A Active JP5661572B2 (ja) | 2009-07-21 | 2011-07-06 | インスリン測定方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010546566A Expired - Fee Related JP4782249B2 (ja) | 2009-07-21 | 2010-07-21 | インスリン測定方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9476891B2 (enExample) |
| EP (1) | EP2458378B1 (enExample) |
| JP (2) | JP4782249B2 (enExample) |
| KR (1) | KR101366353B1 (enExample) |
| CN (1) | CN102246039A (enExample) |
| AU (1) | AU2010274320B2 (enExample) |
| BR (1) | BRPI1005176B1 (enExample) |
| CA (1) | CA2739310C (enExample) |
| MX (1) | MX2011003927A (enExample) |
| MY (1) | MY151976A (enExample) |
| WO (1) | WO2011010673A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012325697B2 (en) * | 2011-10-21 | 2015-11-26 | Decimadx, Llc | Point-of care immunoassay for quantitative small analyte detection |
| ES2734130T3 (es) * | 2012-08-17 | 2019-12-04 | Morphosys Ag | Anticuerpos específicos de complejos y fragmentos de anticuerpo y su uso |
| WO2014157723A1 (ja) | 2013-03-29 | 2014-10-02 | 積水メディカル株式会社 | インスリン測定方法 |
| JP6182027B2 (ja) * | 2013-09-10 | 2017-08-16 | デンカ生研株式会社 | Ｂ型インフルエンザウイルスの測定方法 |
| CN105866420B (zh) * | 2015-01-22 | 2018-11-16 | 艾托金生物医药（苏州）有限公司 | 一种检测免疫原的方法和装置 |
| CN106918708A (zh) * | 2015-12-28 | 2017-07-04 | 北京九强生物技术股份有限公司 | 一种用于检测胰岛素的竞争法胶乳增强免疫透射比浊试剂盒 |
| JP6862845B2 (ja) * | 2016-01-22 | 2021-04-21 | 日立化成ダイアグノスティックス・システムズ株式会社 | 可溶性インターロイキン−２受容体の測定方法及び測定用試薬 |
| CN116449031A (zh) * | 2016-07-29 | 2023-07-18 | Diazyme 研究室有限公司 | 用于测定维生素d的方法和成分 |
| CN112888946B (zh) * | 2018-10-09 | 2024-08-20 | 积水医疗株式会社 | 富含亮氨酸的α2糖蛋白的免疫测定法和测定试剂 |
| CN111690064A (zh) * | 2020-06-24 | 2020-09-22 | 合肥天麦生物科技发展有限公司 | 一种胰岛素原前体蛋白的检测方法及其ppi单克隆抗体的制备方法 |
| CN114195892B (zh) * | 2020-09-18 | 2024-08-13 | 苏州鲲鹏生物技术有限公司 | 一种人胰岛素单链前体残留检测控制方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4514505A (en) * | 1982-05-21 | 1985-04-30 | The Trustees Of Columbia University In The City Of New York | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays |
| JPH0619352B2 (ja) * | 1985-06-10 | 1994-03-16 | 帝人株式会社 | ヒト・プロテインｃの測定方法 |
| DE3636724A1 (de) | 1986-10-29 | 1988-06-23 | Joern Dr Med Kekow | Enzymimmunoassay (elisa) zur insulinbestimmung im mikrotiterplattensystem |
| JPH0198968A (ja) | 1987-10-12 | 1989-04-17 | Tosoh Corp | ヒス・インスリンの測定方法 |
| JPH01148962A (ja) | 1987-12-07 | 1989-06-12 | Tosoh Corp | インスリン免疫測定法 |
| DE3806430A1 (de) * | 1988-02-29 | 1989-09-07 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines proteins nach dem prinzip des fluoreszenz-polarisations-immunoassays |
| US5583003A (en) * | 1989-09-25 | 1996-12-10 | Agen Limited | Agglutination assay |
| JPH03118472A (ja) | 1989-09-29 | 1991-05-21 | Sekisui Chem Co Ltd | インスリン定量方法及び定量試薬 |
| JPH05504841A (ja) * | 1990-09-14 | 1993-07-22 | バイオサイト・ダイアグノスティックス・インコーポレイテッド | リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途 |
| JPH05297000A (ja) * | 1992-04-17 | 1993-11-12 | S R L:Kk | インスリン抗体の測定方法 |
| JP3479100B2 (ja) * | 1993-06-02 | 2003-12-15 | 帝国臓器製薬株式会社 | 免疫化学的簡易半定量方法および装置 |
| US5561049A (en) * | 1994-09-21 | 1996-10-01 | Behringwerke Ag | Method for detecting antibodies |
| US6103536A (en) * | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
| AU2002313319B2 (en) * | 2001-07-02 | 2007-05-10 | Sekisui Medical Co., Ltd. | Carrier particle latex for assay reagent and assay reagent |
| FI20022048A0 (fi) * | 2002-11-18 | 2002-11-18 | Valtion Teknillinen | Ei-kompetetiivinen immunomääritys pienille analyyteille |
| CN101087877B (zh) * | 2004-12-28 | 2012-08-08 | 第一化学药品株式会社 | 抗人可溶性血纤蛋白单克隆抗体及使用该抗体的免疫学测定方法 |
| JP4448149B2 (ja) | 2007-02-19 | 2010-04-07 | 浜松ホトニクス株式会社 | 蛍光免疫測定方法 |
| MX2010007342A (es) * | 2008-01-04 | 2010-08-26 | Biodel Inc | Formulaciones de insulina para la liberacion de insulina como una funcion de los niveles de glucosa en el tejido. |
| JP5115852B2 (ja) | 2008-04-28 | 2013-01-09 | 国立大学法人電気通信大学 | コグニティブ無線通信システム、通信方法、および通信機器 |
| US20110165701A1 (en) * | 2008-09-05 | 2011-07-07 | Yuki Takahashi | Monoclonal antibody and immunoassay using the same |
-
2010
- 2010-07-21 WO PCT/JP2010/062261 patent/WO2011010673A1/ja not_active Ceased
- 2010-07-21 US US13/122,930 patent/US9476891B2/en active Active
- 2010-07-21 MX MX2011003927A patent/MX2011003927A/es active IP Right Grant
- 2010-07-21 BR BRPI1005176-7A patent/BRPI1005176B1/pt not_active IP Right Cessation
- 2010-07-21 CA CA2739310A patent/CA2739310C/en active Active
- 2010-07-21 CN CN2010800035212A patent/CN102246039A/zh active Pending
- 2010-07-21 MY MYPI2011001622 patent/MY151976A/en unknown
- 2010-07-21 AU AU2010274320A patent/AU2010274320B2/en not_active Ceased
- 2010-07-21 EP EP10802293.0A patent/EP2458378B1/en not_active Not-in-force
- 2010-07-21 KR KR1020117013678A patent/KR101366353B1/ko active Active
- 2010-07-21 JP JP2010546566A patent/JP4782249B2/ja not_active Expired - Fee Related
-
2011
- 2011-07-06 JP JP2011149985A patent/JP5661572B2/ja active Active
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