JP2011088902A5 - - Google Patents

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JP2011088902A5
JP2011088902A5 JP2010265830A JP2010265830A JP2011088902A5 JP 2011088902 A5 JP2011088902 A5 JP 2011088902A5 JP 2010265830 A JP2010265830 A JP 2010265830A JP 2010265830 A JP2010265830 A JP 2010265830A JP 2011088902 A5 JP2011088902 A5 JP 2011088902A5
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alkyl
hydrogen
composition
hormone
stereoisomer
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JP2010265830A
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JP5226760B2 (ja
JP2011088902A (ja
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JP2010265830A 2003-07-07 2010-11-29 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストとしてのピリミジン−2,4−ジオン誘導体 Expired - Lifetime JP5226760B2 (ja)

Applications Claiming Priority (2)

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US48543403P 2003-07-07 2003-07-07
US60/485,434 2003-07-07

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JP2006518842A Division JP4722844B2 (ja) 2003-07-07 2004-07-06 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストとしてのピリミジン−2,4−ジオン誘導体

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JP2011088902A JP2011088902A (ja) 2011-05-06
JP2011088902A5 true JP2011088902A5 (https=) 2012-01-19
JP5226760B2 JP5226760B2 (ja) 2013-07-03

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JP2006518842A Expired - Lifetime JP4722844B2 (ja) 2003-07-07 2004-07-06 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストとしてのピリミジン−2,4−ジオン誘導体
JP2010265830A Expired - Lifetime JP5226760B2 (ja) 2003-07-07 2010-11-29 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストとしてのピリミジン−2,4−ジオン誘導体

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JP2006518842A Expired - Lifetime JP4722844B2 (ja) 2003-07-07 2004-07-06 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストとしてのピリミジン−2,4−ジオン誘導体

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US (3) US7056927B2 (https=)
EP (1) EP1646389B1 (https=)
JP (2) JP4722844B2 (https=)
KR (1) KR101139148B1 (https=)
CN (1) CN100424078C (https=)
AT (1) ATE407679T1 (https=)
AU (1) AU2004257639B2 (https=)
BR (1) BRPI0412314B8 (https=)
CA (1) CA2531508C (https=)
CY (1) CY1108656T1 (https=)
DE (1) DE602004016516D1 (https=)
DK (1) DK1646389T3 (https=)
EA (1) EA010370B1 (https=)
ES (1) ES2314448T3 (https=)
HR (1) HRP20080646T3 (https=)
IL (1) IL172833A (https=)
MX (1) MXPA06000297A (https=)
NO (1) NO334897B1 (https=)
NZ (1) NZ544747A (https=)
PL (1) PL1646389T3 (https=)
PT (1) PT1646389E (https=)
SI (1) SI1646389T1 (https=)
WO (1) WO2005007165A1 (https=)
ZA (1) ZA200600475B (https=)

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CN111698992A (zh) * 2017-08-18 2020-09-22 艾伯维公司 用于治疗子宫内膜异位症、子宫肌瘤、多囊卵巢综合症或子宫腺肌症的药物配制物
CN107935863A (zh) * 2017-11-30 2018-04-20 厦门海乐景生化有限公司 Elagolix的关键原料化合物C的合成方法
CN110938037A (zh) * 2018-09-21 2020-03-31 苏州鹏旭医药科技有限公司 一种依拉戈利钠盐药物中间体的制备方法
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CN109970663B (zh) * 2017-12-27 2023-04-11 上海科胜药物研发有限公司 一种制备噁拉戈利中间体的方法
CN108129400B (zh) * 2017-12-29 2021-10-15 安帝康(无锡)生物科技有限公司 氘代噁拉戈利衍生物及其用途
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CN110669013A (zh) * 2018-07-03 2020-01-10 江苏海悦康医药科技有限公司 一种噁拉戈利中间体的制备方法
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CN109293634A (zh) * 2018-12-04 2019-02-01 中国药科大学 恶拉戈利杂质的制备方法
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CN109651265A (zh) * 2019-02-16 2019-04-19 安徽诺全药业有限公司 一种Elagolix的制备方法
CN109810065B (zh) * 2019-02-16 2022-07-15 安徽华胜医药科技有限公司 一种恶拉戈利的合成方法
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CN110372609B (zh) * 2019-07-25 2021-04-09 奥锐特药业股份有限公司 一种噁拉戈利钠盐的纯化方法
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TWI755055B (zh) * 2019-09-18 2022-02-11 台灣神隆股份有限公司 用於製備惡拉戈利鈉及其中間體的方法
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CN111116490A (zh) * 2020-01-15 2020-05-08 奥锐特药业股份有限公司 一种噁拉戈利中间体水杨酸盐的制备与纯化方法
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