JP2010539187A5 - - Google Patents

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Publication number
JP2010539187A5
JP2010539187A5 JP2010525103A JP2010525103A JP2010539187A5 JP 2010539187 A5 JP2010539187 A5 JP 2010539187A5 JP 2010525103 A JP2010525103 A JP 2010525103A JP 2010525103 A JP2010525103 A JP 2010525103A JP 2010539187 A5 JP2010539187 A5 JP 2010539187A5
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JP
Japan
Prior art keywords
group
dioxo
dihydropyrimidin
tert
butyl
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Application number
JP2010525103A
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English (en)
Japanese (ja)
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JP2010539187A (ja
JP5734655B2 (ja
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Priority claimed from PCT/US2008/076592 external-priority patent/WO2009039134A1/en
Publication of JP2010539187A publication Critical patent/JP2010539187A/ja
Publication of JP2010539187A5 publication Critical patent/JP2010539187A5/ja
Application granted granted Critical
Publication of JP5734655B2 publication Critical patent/JP5734655B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010525103A 2007-09-17 2008-09-17 抗感染症ピリミジンおよびその使用 Expired - Fee Related JP5734655B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US97288107P 2007-09-17 2007-09-17
US60/972,881 2007-09-17
US9679208P 2008-09-13 2008-09-13
US61/096,792 2008-09-13
PCT/US2008/076592 WO2009039134A1 (en) 2007-09-17 2008-09-17 Anti-infective pyrimidines and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2012221886A Division JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Division JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Publications (3)

Publication Number Publication Date
JP2010539187A JP2010539187A (ja) 2010-12-16
JP2010539187A5 true JP2010539187A5 (en:Method) 2013-08-15
JP5734655B2 JP5734655B2 (ja) 2015-06-17

Family

ID=40308557

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010525103A Expired - Fee Related JP5734655B2 (ja) 2007-09-17 2008-09-17 抗感染症ピリミジンおよびその使用
JP2012221886A Expired - Fee Related JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Pending JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012221886A Expired - Fee Related JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Pending JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Country Status (21)

Country Link
US (3) US8188104B2 (en:Method)
EP (3) EP2639226B1 (en:Method)
JP (3) JP5734655B2 (en:Method)
CN (4) CN104628655A (en:Method)
AT (1) ATE519746T1 (en:Method)
CA (2) CA2849420C (en:Method)
CY (3) CY1115514T1 (en:Method)
DK (3) DK2203431T3 (en:Method)
ES (3) ES2368879T3 (en:Method)
HR (2) HRP20110809T1 (en:Method)
HU (1) HUS1500013I1 (en:Method)
LT (1) LTC2203431I2 (en:Method)
LU (1) LU92666I2 (en:Method)
MX (1) MX2010002902A (en:Method)
NL (1) NL300729I1 (en:Method)
NO (1) NO2015011I1 (en:Method)
PL (3) PL2368882T3 (en:Method)
PT (3) PT2203431E (en:Method)
RU (2) RU2539570C2 (en:Method)
SI (2) SI2368882T1 (en:Method)
WO (1) WO2009039134A1 (en:Method)

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EP2598482B1 (en) 2010-07-29 2018-04-04 Oryzon Genomics, S.A. Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use
US9006449B2 (en) 2010-07-29 2015-04-14 Oryzon Genomics, S.A. Cyclopropylamine derivatives useful as LSD1 inhibitors
WO2012020725A1 (ja) * 2010-08-10 2012-02-16 塩野義製薬株式会社 Ｎｐｙ ｙ５受容体拮抗作用を有するヘテロ環誘導体
US9061966B2 (en) 2010-10-08 2015-06-23 Oryzon Genomics S.A. Cyclopropylamine inhibitors of oxidases
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WO2012107498A1 (en) 2011-02-08 2012-08-16 Oryzon Genomics S.A. Lysine demethylase inhibitors for myeloproliferative disorders
CN102675092B (zh) * 2011-03-14 2014-11-05 江苏中丹药物研究有限公司 一种制备2-芳基-2,2-二甲基乙酸甲酯的方法
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US9469597B2 (en) 2011-10-20 2016-10-18 Oryzon Genomics S.A. (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
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CN106065009B (zh) * 2014-06-28 2019-03-01 广东东阳光药业有限公司 作为丙型肝炎抑制剂的化合物及其在药物中的应用
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CN108290844B (zh) * 2016-05-27 2021-04-30 深圳市塔吉瑞生物医药有限公司 一种取代的萘环化合物及药物组合物及其应用
CN110483496B (zh) * 2019-07-17 2021-05-04 杭州市西溪医院 一类具有尿嘧啶-苯并噻唑结构衍生物、其制备方法及抗hcv药物的应用
CN111518036A (zh) * 2020-04-29 2020-08-11 杭州勇诚睿生物科技有限公司 一种达沙布韦关键中间体的制备方法
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