JP2010528987A - Ｃ型肝炎ウイルス複製の新規大環状阻害剤 - Google Patents
Ｃ型肝炎ウイルス複製の新規大環状阻害剤 Download PDFInfo
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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| PCT/US2008/062552 WO2008137779A2 (en) | 2007-05-03 | 2008-05-02 | Novel macrocyclic inhibitors of hepatitis c virus replication |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011520906A (ja) * | 2008-05-15 | 2011-07-21 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤 |
| WO2013129549A1 (ja) * | 2012-02-29 | 2013-09-06 | 東レ株式会社 | 体腔液貯留抑制剤 |
| JP2014502620A (ja) * | 2010-12-30 | 2014-02-03 | エナンタ ファーマシューティカルズ インコーポレイテッド | 大環状ｃ型肝炎セリンプロテアーゼ阻害剤 |
| JP2014508116A (ja) * | 2010-12-14 | 2014-04-03 | メルク・シャープ・アンド・ドーム・コーポレーション | 大環状ラクタムの調製のための方法および中間体 |
| JP2015533836A (ja) * | 2012-10-19 | 2015-11-26 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｃ型肝炎ウイルス阻害剤 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003007697A (ja) * | 2001-06-21 | 2003-01-10 | Hitachi Kokusai Electric Inc | 半導体装置の製造方法、基板処理方法および基板処理装置 |
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| US7491794B2 (en) * | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
| AU2006276246B2 (en) * | 2005-07-25 | 2012-09-27 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis C virus replication |
| ES2356776T3 (es) * | 2005-10-11 | 2011-04-13 | Intermune, Inc. | Compuestos y métodos para inhibir la replicación del virus de la hepatitis. |
| RU2008152171A (ru) * | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
| JP2010526834A (ja) | 2007-05-10 | 2010-08-05 | インターミューン・インコーポレーテッド | Ｃ型肝炎ウイルス複製の新規ペプチド阻害剤 |
| WO2009142842A2 (en) | 2008-04-15 | 2009-11-26 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
| US20090285774A1 (en) * | 2008-05-15 | 2009-11-19 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US8207341B2 (en) | 2008-09-04 | 2012-06-26 | Bristol-Myers Squibb Company | Process or synthesizing substituted isoquinolines |
| UY32099A (es) | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
| AR075584A1 (es) * | 2009-02-27 | 2011-04-20 | Intermune Inc | COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO. |
| TW201040181A (en) | 2009-04-08 | 2010-11-16 | Idenix Pharmaceuticals Inc | Macrocyclic serine protease inhibitors |
| US8232246B2 (en) | 2009-06-30 | 2012-07-31 | Abbott Laboratories | Anti-viral compounds |
| EP2461811B1 (en) | 2009-08-05 | 2016-04-20 | Idenix Pharmaceuticals LLC. | Macrocyclic serine protease inhibitors useful against viral infections, particularly hcv |
| EP2470189A4 (en) * | 2009-08-27 | 2013-01-23 | Merck Sharp & Dohme | METHOD FOR PRODUCING PROTEASE INHIBITORS OF HEPATITIS C VIRUS |
| CN102741270B (zh) | 2009-09-28 | 2015-07-22 | 英特穆恩公司 | C型肝炎病毒复制的环肽抑制剂 |
| MX2012003171A (es) * | 2009-09-28 | 2012-04-11 | Hoffmann La Roche | Novedosos inhibidores macrociclicos de la replicacion del virus de hepatitis c. |
| KR20140003521A (ko) | 2010-12-30 | 2014-01-09 | 이난타 파마슈티칼스, 인코포레이티드 | 페난트리딘 매크로사이클릭 ｃ형 간염 세린 프로테아제 억제제 |
| AR085352A1 (es) | 2011-02-10 | 2013-09-25 | Idenix Pharmaceuticals Inc | Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv |
| US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EP2744331A4 (en) | 2011-08-19 | 2015-01-21 | Merck Sharp & Dohme | METHOD AND INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF MACROLACTAMEN |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| DE112012002748T5 (de) | 2011-10-21 | 2014-07-31 | Abbvie Inc. | Verfahren zur Behandlung von HCV umfassend mindestens zwei direkt wirkende antivirale Wirkstoffe, Ribavirin aber nicht Interferon |
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| JP2011520906A (ja) * | 2008-05-15 | 2011-07-21 | ブリストル−マイヤーズ スクイブ カンパニー | Ｃ型肝炎ウイルス阻害剤 |
| JP2014508116A (ja) * | 2010-12-14 | 2014-04-03 | メルク・シャープ・アンド・ドーム・コーポレーション | 大環状ラクタムの調製のための方法および中間体 |
| JP2014502620A (ja) * | 2010-12-30 | 2014-02-03 | エナンタ ファーマシューティカルズ インコーポレイテッド | 大環状ｃ型肝炎セリンプロテアーゼ阻害剤 |
| WO2013129549A1 (ja) * | 2012-02-29 | 2013-09-06 | 東レ株式会社 | 体腔液貯留抑制剤 |
| JP2015533836A (ja) * | 2012-10-19 | 2015-11-26 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｃ型肝炎ウイルス阻害剤 |
Also Published As
| Publication number | Publication date |
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| MA31496B1 (fr) | 2010-07-01 |
| AP2009005053A0 (en) | 2009-12-31 |
| IL201757A0 (en) | 2010-06-16 |
| ECSP099780A (es) | 2010-01-29 |
| BRPI0811020A2 (pt) | 2015-07-21 |
| EA200971026A1 (ru) | 2011-02-28 |
| TW200906830A (en) | 2009-02-16 |
| WO2008137779A3 (en) | 2009-01-08 |
| MX2009011867A (es) | 2010-03-22 |
| NZ581606A (en) | 2012-06-29 |
| TN2009000457A1 (en) | 2011-03-31 |
| WO2008137779A2 (en) | 2008-11-13 |
| KR20100024920A (ko) | 2010-03-08 |
| EP2160392A2 (en) | 2010-03-10 |
| SG174809A1 (en) | 2011-10-28 |
| AU2008247509A1 (en) | 2008-11-13 |
| CL2008001274A1 (es) | 2008-11-03 |
| AR066448A1 (es) | 2009-08-19 |
| CA2686138A1 (en) | 2008-11-13 |
| EP2177523A1 (en) | 2010-04-21 |
| CN101784549A (zh) | 2010-07-21 |
| CO6251243A2 (es) | 2011-02-21 |
| US20090155209A1 (en) | 2009-06-18 |
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