JP2010522541A5 - - Google Patents
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- Publication number
- JP2010522541A5 JP2010522541A5 JP2010500047A JP2010500047A JP2010522541A5 JP 2010522541 A5 JP2010522541 A5 JP 2010522541A5 JP 2010500047 A JP2010500047 A JP 2010500047A JP 2010500047 A JP2010500047 A JP 2010500047A JP 2010522541 A5 JP2010522541 A5 JP 2010522541A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sucralose
- terminus
- tas2r bitter
- tag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90914307P | 2007-03-30 | 2007-03-30 | |
| US60/909,143 | 2007-03-30 | ||
| US96254907P | 2007-07-30 | 2007-07-30 | |
| US60/962,549 | 2007-07-30 | ||
| PCT/CH2008/000134 WO2008119195A1 (en) | 2007-03-30 | 2008-03-27 | Methods to identify modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522541A JP2010522541A (ja) | 2010-07-08 |
| JP2010522541A5 true JP2010522541A5 (enExample) | 2011-05-12 |
| JP5465656B2 JP5465656B2 (ja) | 2014-04-09 |
Family
ID=39709251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500047A Active JP5465656B2 (ja) | 2007-03-30 | 2008-03-27 | 調節物質を同定するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8187822B2 (enExample) |
| EP (1) | EP2137322B1 (enExample) |
| JP (1) | JP5465656B2 (enExample) |
| KR (1) | KR20100016044A (enExample) |
| WO (1) | WO2008119195A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009149577A1 (en) | 2008-06-13 | 2009-12-17 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor tas2r44 |
| WO2010015097A1 (en) * | 2008-08-07 | 2010-02-11 | Givaudan Sa | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46 |
| CN102369275A (zh) * | 2009-02-02 | 2012-03-07 | 卓莫赛尔公司 | 新型细胞系和方法 |
| US9347934B2 (en) * | 2011-10-20 | 2016-05-24 | Chromocell Corporation | Assays for identifying compounds that modulate bitter taste |
| WO2013072332A1 (en) | 2011-11-14 | 2013-05-23 | Givaudan Sa | Methods of using antagonists of bitter taste receptors |
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
| WO2014149829A1 (en) | 2013-03-15 | 2014-09-25 | Afb International | Feline bitter taste receptors and methods |
| WO2014176336A1 (en) | 2013-04-24 | 2014-10-30 | Chromocell Corporation | Assays for identifying compounds that modulate bitter taste |
| JP6367315B2 (ja) | 2013-05-10 | 2018-08-01 | ペプシコ, インコーポレイテッドPepsiCo Inc. | 潜在的味覚調節物質を特定するためのモデルとしての細胞 |
| JP6211685B2 (ja) * | 2013-05-10 | 2017-10-11 | ペプシコ, インコーポレイテッドPepsiCo Inc. | 味覚受容体インターナリゼーションアッセイ |
| CN104713927A (zh) * | 2015-03-16 | 2015-06-17 | 常州大学 | 一种检测食品中三氯蔗糖的电化学方法 |
| WO2017019890A1 (en) * | 2015-07-28 | 2017-02-02 | Mars, Incorporated | Screening methods using canine t2r receptors and pet food products and compositions identified using the same |
| EP4493928A1 (en) * | 2022-04-19 | 2025-01-22 | Firmenich Incorporated | Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5825980B2 (ja) | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| WO1990005745A1 (en) * | 1988-11-18 | 1990-05-31 | The General Hospital Corporation | A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN |
| US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
| US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
| EP1214343A2 (en) | 1999-09-10 | 2002-06-19 | The Regents Of The University Of California | T2r taste receptor family |
| CN100447156C (zh) * | 2000-04-07 | 2008-12-31 | 塞诺米克斯公司 | T2r味觉受体及其编码基因 |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7022488B2 (en) * | 2003-02-03 | 2006-04-04 | Senomyx, Inc. | Functional coupling of T1Rs and T2Rs by Gi proteins, and cells-based assays for the identification of T1R and T2R modulators |
| US7413535B2 (en) * | 2001-07-27 | 2008-08-19 | Illinois Tool Works Inc. | Method for manufacturing tamper evident reclosable plastic bags |
| EP2270155A3 (en) | 2002-09-25 | 2011-08-10 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| EP1581555B1 (en) * | 2002-12-18 | 2008-04-30 | Givaudan SA | Chimeric alpha q-gustducin g-proteins |
| AU2004258071A1 (en) * | 2003-06-19 | 2005-01-27 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Variants of human taste receptor genes |
| EP1737442B1 (en) * | 2004-04-20 | 2015-01-07 | Deutsches Institut Für Ernährungsforschung - Stiftung Des Öffentlichen Rechts - Vertreten Durch Den Stiftungsvorstand | Agonists of a bitter taste receptor and uses thereof |
| WO2006053771A2 (en) | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| JP4688517B2 (ja) * | 2005-02-15 | 2011-05-25 | 小川香料株式会社 | 高甘味度甘味料の呈味改善剤 |
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2008
- 2008-03-27 US US12/593,155 patent/US8187822B2/en active Active
- 2008-03-27 KR KR1020097022661A patent/KR20100016044A/ko not_active Ceased
- 2008-03-27 EP EP08714784A patent/EP2137322B1/en active Active
- 2008-03-27 WO PCT/CH2008/000134 patent/WO2008119195A1/en not_active Ceased
- 2008-03-27 JP JP2010500047A patent/JP5465656B2/ja active Active
-
2012
- 2012-05-26 US US13/481,797 patent/US8597896B2/en active Active