JP2012506237A5 - - Google Patents
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- Publication number
- JP2012506237A5 JP2012506237A5 JP2011531514A JP2011531514A JP2012506237A5 JP 2012506237 A5 JP2012506237 A5 JP 2012506237A5 JP 2011531514 A JP2011531514 A JP 2011531514A JP 2011531514 A JP2011531514 A JP 2011531514A JP 2012506237 A5 JP2012506237 A5 JP 2012506237A5
- Authority
- JP
- Japan
- Prior art keywords
- lip1
- seq
- sequence number
- sign
- variable domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108060003951 Immunoglobulin Proteins 0.000 claims 14
- 102000018358 immunoglobulin Human genes 0.000 claims 14
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 102100023441 Centromere protein J Human genes 0.000 claims 6
- 101000907924 Homo sapiens Centromere protein J Proteins 0.000 claims 6
- 101000693082 Homo sapiens Serine/threonine-protein kinase 11-interacting protein Proteins 0.000 claims 6
- YAFQFNOUYXZVPZ-UHFFFAOYSA-N liproxstatin-1 Chemical compound ClC1=CC=CC(CNC=2C3(CCNCC3)NC3=CC=CC=C3N=2)=C1 YAFQFNOUYXZVPZ-UHFFFAOYSA-N 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 101100112922 Candida albicans CDR3 gene Proteins 0.000 claims 5
- 108010037897 DC-specific ICAM-3 grabbing nonintegrin Proteins 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102100040843 C-type lectin domain family 4 member M Human genes 0.000 claims 1
- 102000006395 Globulins Human genes 0.000 claims 1
- 108010044091 Globulins Proteins 0.000 claims 1
- 101000749311 Homo sapiens C-type lectin domain family 4 member M Proteins 0.000 claims 1
- 108010064600 Intercellular Adhesion Molecule-3 Proteins 0.000 claims 1
- 102100037871 Intercellular adhesion molecule 3 Human genes 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 102000006495 integrins Human genes 0.000 claims 1
- 108010044426 integrins Proteins 0.000 claims 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10708508P | 2008-10-21 | 2008-10-21 | |
| US61/107,085 | 2008-10-21 | ||
| PCT/EP2009/063655 WO2010046337A2 (en) | 2008-10-21 | 2009-10-19 | Ligands that have binding specificity for dc-sign |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012506237A JP2012506237A (ja) | 2012-03-15 |
| JP2012506237A5 true JP2012506237A5 (enExample) | 2012-11-22 |
Family
ID=42062429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011531514A Pending JP2012506237A (ja) | 2008-10-21 | 2009-10-19 | Dc−signに対する結合特異性をもつリガンド |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20110257373A1 (enExample) |
| EP (1) | EP2356149A2 (enExample) |
| JP (1) | JP2012506237A (enExample) |
| KR (1) | KR20110071139A (enExample) |
| CN (1) | CN102257009A (enExample) |
| AR (1) | AR073905A1 (enExample) |
| AU (1) | AU2009306424A1 (enExample) |
| BR (1) | BRPI0919714A2 (enExample) |
| CA (1) | CA2740856A1 (enExample) |
| EA (1) | EA201100488A1 (enExample) |
| IL (1) | IL212086A0 (enExample) |
| MX (1) | MX2011004244A (enExample) |
| TW (1) | TW201019962A (enExample) |
| UY (1) | UY32189A (enExample) |
| WO (1) | WO2010046337A2 (enExample) |
| ZA (1) | ZA201102763B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20110775A1 (es) * | 2008-10-21 | 2011-10-21 | Domantis Ltd | Composicion para dirigirse a las celulas dendriticas |
| EP2793918B1 (en) * | 2011-12-19 | 2019-09-11 | The Rockefeller University | Hdc-sign binding peptides |
| US20250319024A1 (en) * | 2021-08-27 | 2025-10-16 | University Of Georgia Research Foundation, Inc. | Targeted nanoparticles and their uses related to infectious disease |
| CN118184795B (zh) * | 2022-12-13 | 2025-03-21 | 成都维瑾柏鳌生物医药科技有限公司 | 抗hiv-1的重组蛋白及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993025686A1 (en) * | 1992-06-05 | 1993-12-23 | Baxter Diagnostics Inc. | Rabbit single domain antibody and use thereof |
| EP3299393A1 (en) * | 2002-11-08 | 2018-03-28 | Ablynx N.V. | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| NZ540771A (en) * | 2003-01-10 | 2009-05-31 | Ablynx Nv | Recombinant VHH single domain antibody from camelidae against von willebrand factor (vWF) or against collagen |
| EP2357237A1 (en) * | 2003-05-14 | 2011-08-17 | Domantis Limited | A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire |
| DK1639011T3 (da) * | 2003-06-30 | 2009-02-16 | Domantis Ltd | Pegylerede enkelt-domæne antistoffer (dAb) |
| CN102172397B (zh) * | 2003-08-21 | 2013-01-30 | 利普泰克有限公司 | 树突细胞的体内靶向 |
| KR20120133403A (ko) * | 2004-06-01 | 2012-12-10 | 도만티스 리미티드 | 증강된 혈청 반감기를 가지는 이특이성 융합 항체 |
| CA2589800A1 (en) * | 2004-12-02 | 2006-06-08 | Domantis Limited | Bispecific domain antibodies targeting serum albumin and glp-1 or pyy |
| KR20070086896A (ko) * | 2004-12-02 | 2007-08-27 | 도만티스 리미티드 | 항il1r1 단일 도메인 항체 및 치료적 용도 |
| CA2601115A1 (en) * | 2005-03-18 | 2006-09-21 | Domantis Limited | Antibodies against candida antigens |
| EP1963370A1 (en) * | 2005-12-06 | 2008-09-03 | Domantis Limited | Bispecific ligands with binding specificity to cell surface targets and methods of use therefor |
| BRPI0619463A2 (pt) * | 2005-12-06 | 2013-01-08 | Domantis Ltd | ligando, uso do mesmo, mÉtodos para tratar cÂncer e para administrar um tratamento anti-vegf e tratamento anti-egfr a um indivÍduo, composiÇço, dispositivo de dispensaÇço de droga, Ácido nucleico isolado ou recombinante, vetor, cÉlula hospedeira, mÉtodo para produzir um ligando, polipeptÍdeo de domÍnio variÁvel simples de imunoglobulina, e, antagonista de egfr |
| AU2007209202A1 (en) * | 2006-01-24 | 2007-08-02 | Domantis Limited | Ligands that bind IL-4 and/or IL-13 |
| WO2008039432A1 (en) * | 2006-09-26 | 2008-04-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for enhancing an adjuvant |
| WO2008070363A2 (en) * | 2006-10-31 | 2008-06-12 | Domantis Limited | Intrabodies |
| CN101182539A (zh) * | 2007-11-06 | 2008-05-21 | 浙江大学 | Dc-sign启动子荧光素酶报告质粒的构建方法 |
-
2009
- 2009-10-19 AU AU2009306424A patent/AU2009306424A1/en not_active Abandoned
- 2009-10-19 BR BRPI0919714A patent/BRPI0919714A2/pt not_active IP Right Cessation
- 2009-10-19 EP EP09736603A patent/EP2356149A2/en not_active Withdrawn
- 2009-10-19 AR ARP090104011A patent/AR073905A1/es not_active Application Discontinuation
- 2009-10-19 KR KR1020117011399A patent/KR20110071139A/ko not_active Withdrawn
- 2009-10-19 CA CA2740856A patent/CA2740856A1/en not_active Abandoned
- 2009-10-19 US US13/125,384 patent/US20110257373A1/en not_active Abandoned
- 2009-10-19 JP JP2011531514A patent/JP2012506237A/ja active Pending
- 2009-10-19 TW TW098135298A patent/TW201019962A/zh unknown
- 2009-10-19 EA EA201100488A patent/EA201100488A1/ru unknown
- 2009-10-19 MX MX2011004244A patent/MX2011004244A/es not_active Application Discontinuation
- 2009-10-19 CN CN2009801529594A patent/CN102257009A/zh active Pending
- 2009-10-19 WO PCT/EP2009/063655 patent/WO2010046337A2/en not_active Ceased
- 2009-10-20 UY UY0001032189A patent/UY32189A/es unknown
-
2011
- 2011-04-03 IL IL212086A patent/IL212086A0/en unknown
- 2011-04-13 ZA ZA2011/02763A patent/ZA201102763B/en unknown
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