JP5465656B2 - 調節物質を同定するための方法 - Google Patents

調節物質を同定するための方法 Download PDF

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Publication number
JP5465656B2
JP5465656B2 JP2010500047A JP2010500047A JP5465656B2 JP 5465656 B2 JP5465656 B2 JP 5465656B2 JP 2010500047 A JP2010500047 A JP 2010500047A JP 2010500047 A JP2010500047 A JP 2010500047A JP 5465656 B2 JP5465656 B2 JP 5465656B2
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Japan
Prior art keywords
sucralose
cells
seq
receptor
tag
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JP2010500047A
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English (en)
Japanese (ja)
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JP2010522541A5 (enExample
JP2010522541A (ja
Inventor
ブルーネ，ニコル，エルナ，イレーネ
スラック，ジェイ，パトリック
ウングレアヌ，イオアナ，マリア
グレイ，キンバリー
シモンズ，クリストファー，トッド
ペニンピード，ジェニー，エレン エヴァンズ
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ジボダン エス エー
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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/37—Halogenated sugars
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/84—Flavour masking or reducing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/86—Addition of bitterness inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2010500047A 2007-03-30 2008-03-27 調節物質を同定するための方法 Active JP5465656B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90914307P 2007-03-30 2007-03-30
US60/909,143 2007-03-30
US96254907P 2007-07-30 2007-07-30
US60/962,549 2007-07-30
PCT/CH2008/000134 WO2008119195A1 (en) 2007-03-30 2008-03-27 Methods to identify modulators

Publications (3)

Publication Number Publication Date
JP2010522541A JP2010522541A (ja) 2010-07-08
JP2010522541A5 JP2010522541A5 (enExample) 2011-05-12
JP5465656B2 true JP5465656B2 (ja) 2014-04-09

Family

ID=39709251

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010500047A Active JP5465656B2 (ja) 2007-03-30 2008-03-27 調節物質を同定するための方法

Country Status (5)

Country Link
US (2) US8187822B2 (enExample)
EP (1) EP2137322B1 (enExample)
JP (1) JP5465656B2 (enExample)
KR (1) KR20100016044A (enExample)
WO (1) WO2008119195A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2300830B1 (en) 2008-06-13 2015-05-20 Givaudan SA Methods of identifying modulators of the bitter taste receptor tas2r44
EP2329263A1 (en) * 2008-08-07 2011-06-08 Givaudan SA Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46
EP2391711B1 (en) * 2009-02-02 2015-04-08 Chromocell Corporation Novel cell lines and methods
CN103998933B (zh) 2011-10-20 2016-12-14 卓莫赛尔公司 鉴定调节苦味的化合物的测定
WO2013072332A1 (en) 2011-11-14 2013-05-23 Givaudan Sa Methods of using antagonists of bitter taste receptors
MX2015013013A (es) 2013-03-15 2015-12-01 Applied Food Biotech Inc Receptores felinos del gusto amargo y metodos.
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
CN105358983B (zh) 2013-04-24 2018-08-03 卓莫赛尔公司 用于鉴定调节苦味的化合物的测定
CN105339384A (zh) 2013-05-10 2016-02-17 百事可乐公司 作为鉴别潜在味觉调节剂的模型的细胞
RU2665812C2 (ru) * 2013-05-10 2018-09-04 Пепсико, Инк. Метод анализа интернализации вкусовых рецепторов
CN104713927A (zh) * 2015-03-16 2015-06-17 常州大学 一种检测食品中三氯蔗糖的电化学方法
WO2017019890A1 (en) * 2015-07-28 2017-02-02 Mars, Incorporated Screening methods using canine t2r receptors and pet food products and compositions identified using the same
EP4493928A1 (en) * 2022-04-19 2025-01-22 Firmenich Incorporated Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5825980B2 (ja) 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
CA2003345A1 (en) * 1988-11-18 1990-05-18 Joel F. Habener Camp-responsive transcriptional enhancer binding protein
US5462856A (en) 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
CA2384777A1 (en) 1999-09-10 2001-03-15 Charles S. Zuker T2r taste receptor family
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
WO2001077676A1 (en) * 2000-04-07 2001-10-18 Senomyx, Inc. T2r taste receptors and genes encoding same
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7413535B2 (en) * 2001-07-27 2008-08-19 Illinois Tool Works Inc. Method for manufacturing tamper evident reclosable plastic bags
EP2267128A3 (en) 2002-09-25 2011-08-10 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
JP4654038B2 (ja) * 2002-12-18 2011-03-16 ジボダン エス エー キメラアルファｑ−ガストデューシンｇタンパク質
WO2004069191A2 (en) 2003-02-03 2004-08-19 Senomyx Inc. Identification of t1r and t2r modulators
AU2004258071A1 (en) * 2003-06-19 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
JP4812752B2 (ja) * 2004-04-20 2011-11-09 ドイチェス インシュティテュート フェア エルネールングスフォルシュング 苦味受容体のアゴニストおよびその使用
EP1815015B1 (en) 2004-11-18 2012-05-23 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts Agonists of bitter taste receptors and uses thereof
JP4688517B2 (ja) * 2005-02-15 2011-05-25 小川香料株式会社 高甘味度甘味料の呈味改善剤

Also Published As

Publication number Publication date
WO2008119195A1 (en) 2008-10-09
EP2137322A1 (en) 2009-12-30
US20120237953A1 (en) 2012-09-20
EP2137322B1 (en) 2013-02-27
US20100129833A1 (en) 2010-05-27
JP2010522541A (ja) 2010-07-08
KR20100016044A (ko) 2010-02-12
US8187822B2 (en) 2012-05-29
US8597896B2 (en) 2013-12-03

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