JP5465656B2 - 調節物質を同定するための方法 - Google Patents

調節物質を同定するための方法 Download PDF

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Publication number
JP5465656B2
JP5465656B2 JP2010500047A JP2010500047A JP5465656B2 JP 5465656 B2 JP5465656 B2 JP 5465656B2 JP 2010500047 A JP2010500047 A JP 2010500047A JP 2010500047 A JP2010500047 A JP 2010500047A JP 5465656 B2 JP5465656 B2 JP 5465656B2
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Japan
Prior art keywords
sucralose
cells
seq
receptor
tag
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JP2010500047A
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English (en)
Japanese (ja)
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JP2010522541A5 (enExample
JP2010522541A (ja
Inventor
ブルーネ，ニコル，エルナ，イレーネ
スラック，ジェイ，パトリック
ウングレアヌ，イオアナ，マリア
グレイ，キンバリー
シモンズ，クリストファー，トッド
ペニンピード，ジェニー，エレン エヴァンズ
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ジボダン エス エー
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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/37—Halogenated sugars
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/84—Flavour masking or reducing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/86—Addition of bitterness inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2010500047A 2007-03-30 2008-03-27 調節物質を同定するための方法 Active JP5465656B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90914307P 2007-03-30 2007-03-30
US60/909,143 2007-03-30
US96254907P 2007-07-30 2007-07-30
US60/962,549 2007-07-30
PCT/CH2008/000134 WO2008119195A1 (en) 2007-03-30 2008-03-27 Methods to identify modulators

Publications (3)

Publication Number Publication Date
JP2010522541A JP2010522541A (ja) 2010-07-08
JP2010522541A5 JP2010522541A5 (enExample) 2011-05-12
JP5465656B2 true JP5465656B2 (ja) 2014-04-09

Family

ID=39709251

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010500047A Active JP5465656B2 (ja) 2007-03-30 2008-03-27 調節物質を同定するための方法

Country Status (5)

Country Link
US (2) US8187822B2 (enExample)
EP (1) EP2137322B1 (enExample)
JP (1) JP5465656B2 (enExample)
KR (1) KR20100016044A (enExample)
WO (1) WO2008119195A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009149577A1 (en) 2008-06-13 2009-12-17 Givaudan Sa Methods of identifying modulators of the bitter taste receptor tas2r44
WO2010015097A1 (en) * 2008-08-07 2010-02-11 Givaudan Sa Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46
CN102369275A (zh) * 2009-02-02 2012-03-07 卓莫赛尔公司 新型细胞系和方法
US9347934B2 (en) * 2011-10-20 2016-05-24 Chromocell Corporation Assays for identifying compounds that modulate bitter taste
WO2013072332A1 (en) 2011-11-14 2013-05-23 Givaudan Sa Methods of using antagonists of bitter taste receptors
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
WO2014149829A1 (en) 2013-03-15 2014-09-25 Afb International Feline bitter taste receptors and methods
WO2014176336A1 (en) 2013-04-24 2014-10-30 Chromocell Corporation Assays for identifying compounds that modulate bitter taste
JP6367315B2 (ja) 2013-05-10 2018-08-01 ペプシコ, インコーポレイテッドPepsiCo Inc. 潜在的味覚調節物質を特定するためのモデルとしての細胞
JP6211685B2 (ja) * 2013-05-10 2017-10-11 ペプシコ, インコーポレイテッドPepsiCo Inc. 味覚受容体インターナリゼーションアッセイ
CN104713927A (zh) * 2015-03-16 2015-06-17 常州大学 一种检测食品中三氯蔗糖的电化学方法
WO2017019890A1 (en) * 2015-07-28 2017-02-02 Mars, Incorporated Screening methods using canine t2r receptors and pet food products and compositions identified using the same
EP4493928A1 (en) * 2022-04-19 2025-01-22 Firmenich Incorporated Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5825980B2 (ja) 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
WO1990005745A1 (en) * 1988-11-18 1990-05-31 The General Hospital Corporation A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN
US5462856A (en) 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
EP1214343A2 (en) 1999-09-10 2002-06-19 The Regents Of The University Of California T2r taste receptor family
CN100447156C (zh) * 2000-04-07 2008-12-31 塞诺米克斯公司 T2r味觉受体及其编码基因
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7022488B2 (en) * 2003-02-03 2006-04-04 Senomyx, Inc. Functional coupling of T1Rs and T2Rs by Gi proteins, and cells-based assays for the identification of T1R and T2R modulators
US7413535B2 (en) * 2001-07-27 2008-08-19 Illinois Tool Works Inc. Method for manufacturing tamper evident reclosable plastic bags
EP2270155A3 (en) 2002-09-25 2011-08-10 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bitter taste receptors
EP1581555B1 (en) * 2002-12-18 2008-04-30 Givaudan SA Chimeric alpha q-gustducin g-proteins
AU2004258071A1 (en) * 2003-06-19 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
EP1737442B1 (en) * 2004-04-20 2015-01-07 Deutsches Institut Für Ernährungsforschung - Stiftung Des Öffentlichen Rechts - Vertreten Durch Den Stiftungsvorstand Agonists of a bitter taste receptor and uses thereof
WO2006053771A2 (en) 2004-11-18 2006-05-26 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts Agonists of bitter taste receptors and uses thereof
JP4688517B2 (ja) * 2005-02-15 2011-05-25 小川香料株式会社 高甘味度甘味料の呈味改善剤

Also Published As

Publication number Publication date
US8597896B2 (en) 2013-12-03
KR20100016044A (ko) 2010-02-12
EP2137322B1 (en) 2013-02-27
US8187822B2 (en) 2012-05-29
EP2137322A1 (en) 2009-12-30
WO2008119195A1 (en) 2008-10-09
US20120237953A1 (en) 2012-09-20
US20100129833A1 (en) 2010-05-27
JP2010522541A (ja) 2010-07-08

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