|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
|
US8236557B2
(en)
*
|
2008-05-28 |
2012-08-07 |
University Of Missouri-Columbia |
Hybrid-AAV vectors to deliver large gene expression cassette
|
|
US8889641B2
(en)
|
2009-02-11 |
2014-11-18 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
ES2683695T3
(es)
|
2010-01-12 |
2018-09-27 |
The University Of North Carolina At Chapel Hill |
Repeticiones terminales invertidas restrictivas para vectores virales
|
|
JP6141021B2
(ja)
*
|
2010-02-05 |
2017-06-07 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
パルボウイルスの形質導入を増強するための組成物および方法
|
|
US9409953B2
(en)
|
2011-02-10 |
2016-08-09 |
The University Of North Carolina At Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
|
WO2013075008A1
(en)
*
|
2011-11-16 |
2013-05-23 |
University Of Florida Research Foundation Inc. |
Aav dual vector systems for gene therapy
|
|
CN103405774A
(zh)
*
|
2012-10-24 |
2013-11-27 |
尹海芳 |
一种新型药物靶向运输辅助剂
|
|
WO2014081855A1
(en)
*
|
2012-11-20 |
2014-05-30 |
Universite De Montreal |
Methods and compositions for muscular dystrophies
|
|
US9624282B2
(en)
*
|
2012-11-26 |
2017-04-18 |
The Curators Of The University Of Missouri |
Microdystrophin peptides and methods for treating muscular dystrophy using the same
|
|
AU2014227766B2
(en)
|
2013-03-15 |
2018-10-04 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding AAV vectors
|
|
EP3517612A1
(en)
|
2013-03-15 |
2019-07-31 |
The University of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
|
AU2016206624B2
(en)
|
2015-01-14 |
2020-08-06 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
|
JP6832280B2
(ja)
*
|
2015-01-16 |
2021-02-24 |
ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ |
新規のマイクロジストロフィンおよび使用の関連する方法
|
|
MX2017010698A
(es)
|
2015-02-20 |
2018-04-30 |
Univ Texas |
Metodos y composiciones para chlamydia atenuada como vacuna y vector.
|
|
GB201507842D0
(en)
*
|
2015-05-07 |
2015-06-17 |
New Royal Holloway & Bedford |
Production of large-sized microdystrophins in an AAV-based vector configuration
|
|
IL314171A
(en)
|
2015-09-28 |
2024-09-01 |
Univ Florida |
Methods and compositions for antibody-evading virus vectors
|
|
WO2017062835A2
(en)
|
2015-10-09 |
2017-04-13 |
Sarepta Therapeutics, Inc. |
Compositions and methods for treating duchenne muscular dystrophy and related disorders
|
|
EP3377042A4
(en)
|
2015-11-16 |
2019-05-29 |
The Research Institute at Nationwide Children's Hospital |
MATERIALS AND METHOD FOR THE TREATMENT OF TITIN-BASED MYOPATHIES AND OTHER TITINOPATHIES
|
|
BR112018011881A2
(pt)
|
2015-12-14 |
2018-12-04 |
The University Of North Carolina At Chapel Hill |
proteínas capsidiais modificadas para liberação aumentada de vetores de parvovírus
|
|
EP4407035A3
(en)
|
2016-04-15 |
2024-10-30 |
Research Institute at Nationwide Children's Hospital |
Adeno-associated virus vector delivery of b-sarcoglycan and microrna-29 and the treatment of muscular dystrophy
|
|
DK3442602T3
(da)
|
2016-04-15 |
2025-05-19 |
Res Inst Nationwide Childrens Hospital |
Adeno-associeret virusvektors frigørelse af mikrodystrofin til behandling af muskeldystrofi
|
|
CA2971303C
(en)
|
2016-06-21 |
2026-03-03 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
|
US11202840B2
(en)
|
2016-06-21 |
2021-12-21 |
The Curators Of The University Of Missouri |
Modified dystrophin proteins
|
|
AU2017301600B2
(en)
|
2016-07-26 |
2022-08-04 |
Biomarin Pharmaceutical Inc. |
Novel adeno-associated virus capsid proteins
|
|
US11207382B2
(en)
|
2016-08-19 |
2021-12-28 |
University Of Florida Research Foundation, Incorporated |
Compositions for treating conditions using recombinant self-complementary adeno-associated virus
|
|
KR20250121159A
(ko)
|
2016-12-07 |
2025-08-11 |
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 |
인터류킨-1 수용체 길항제(IL-1RA) cDNA
|
|
WO2018162748A1
(en)
|
2017-03-10 |
2018-09-13 |
Genethon |
Treatment of glycogen storage disease iii
|
|
IL316259A
(en)
|
2017-03-15 |
2024-12-01 |
Univ North Carolina Chapel Hill |
Polyploid gland associated with virus vectors and methods for preparing and using the same.
|
|
MA47800A
(fr)
|
2017-03-17 |
2020-01-22 |
Univ Newcastle |
Délivrance par vecteur viral adéno-associé d'un fragment de micro-dystrophine pour traiter la dystrophie musculaire
|
|
JP7240675B2
(ja)
|
2017-05-05 |
2023-03-16 |
ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． |
オトフェルリンを発現させるための組成物および方法
|
|
WO2019078916A1
(en)
|
2017-10-18 |
2019-04-25 |
Research Institute At Nationwide Children's Hospital |
ADENO-ASSOCIATED VIRUS VECTOR ADMINISTRATION OF MUSCLE-SPECIFIC MICRO-DYSTROPHINE TO TREAT MUSCLE DYSTROPHY
|
|
US11254652B2
(en)
|
2017-11-22 |
2022-02-22 |
Agios Pharmaceuticals, Inc. |
Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
|
|
AR114350A1
(es)
|
2018-01-31 |
2020-08-26 |
Res Institute At Nationwide ChildrenS Hospital |
Terapia genética para la distrofia muscular de cinturas del tipo 2c
|
|
CA3092107A1
(en)
|
2018-02-28 |
2019-09-06 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for antibody-evading virus vectors
|
|
WO2019195423A1
(en)
|
2018-04-03 |
2019-10-10 |
Stridebio, Inc. |
Virus vectors for targeting ophthalmic tissues
|
|
JP7406677B2
(ja)
|
2018-04-03 |
2023-12-28 |
ギンコ バイオワークス インコーポレイテッド |
抗体を回避するウイルスベクター
|
|
WO2019195444A1
(en)
|
2018-04-03 |
2019-10-10 |
Stridebio, Inc. |
Antibody-evading virus vectors
|
|
CA3099958A1
(en)
|
2018-04-16 |
2019-10-24 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating duchenne muscular dystrophy
|
|
CN119410636A
(zh)
|
2018-04-27 |
2025-02-11 |
分贝治疗公司 |
肌球蛋白15启动子及其用途
|
|
US11660353B2
(en)
|
2018-04-27 |
2023-05-30 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
|
CA3099704A1
(en)
|
2018-05-09 |
2019-11-14 |
Biomarin Pharmaceutical Inc. |
Methods of treating phenylketonuria
|
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
|
US10758629B2
(en)
|
2018-05-29 |
2020-09-01 |
Sarepta Therapeutics, Inc. |
Exon skipping oligomer conjugates for muscular dystrophy
|
|
BR112020025995A2
(pt)
*
|
2018-06-18 |
2021-03-23 |
Research Institute At Nationwide Children's Hospital |
administração de microdistrofina músculo-específica por vetor de vírus adeno-associado para tratar a distrofia muscular
|
|
CA3104113A1
(en)
|
2018-06-22 |
2019-12-26 |
Asklepios Biopharmaceutical, Inc. |
Vectors for gene delivery that persist within cells
|
|
WO2020006458A1
(en)
|
2018-06-29 |
2020-01-02 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus products and methods for treating limb girdle muscular dystrophy 2a
|
|
WO2020093018A1
(en)
|
2018-11-01 |
2020-05-07 |
University Of Florida Research Foundation, Incorporated |
A codon optimized otoferlin aav dual vector gene therapy
|
|
JP7562544B2
(ja)
|
2019-02-08 |
2024-10-07 |
デシベル セラピューティクス インコーポレイテッド |
ミオシン１５プロモーター及びその使用
|
|
EP3921032A4
(en)
|
2019-02-08 |
2022-11-30 |
Decibel Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS
|
|
CA3131390A1
(en)
|
2019-02-26 |
2020-09-03 |
Research Institute Of Nationwide Children's Hospital |
Adeno-associated virus vector delivery of b-sarcoglycan and the treatment of muscular dystrophy
|
|
AR118465A1
(es)
|
2019-03-21 |
2021-10-06 |
Stridebio Inc |
Vectores de virus adenoasociados recombinantes
|
|
WO2020193636A1
(en)
*
|
2019-03-25 |
2020-10-01 |
Genethon |
Production of large-sized quasidystrophins using overlapping aav vectors
|
|
US20220194992A1
(en)
|
2019-04-26 |
2022-06-23 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding aav2.5 vector
|
|
AU2020284255A1
(en)
|
2019-05-30 |
2022-01-06 |
Solid Biosciences Inc. |
Recombinant herpesvirales vector
|
|
US20220280652A1
(en)
*
|
2019-07-10 |
2022-09-08 |
University Of Washington |
Non-viral immuno-targeting
|
|
EP4488287A3
(en)
|
2019-08-21 |
2025-03-05 |
Research Institute at Nationwide Children's Hospital |
Adeno-associated virus vector delivery of alpha-sarcoglycan and the treatment of muscular dystrophy
|
|
KR20220083708A
(ko)
|
2019-10-17 |
2022-06-20 |
스트라이드바이오 인코포레이티드 |
Aav 전달 카세트
|
|
AU2020367532A1
(en)
|
2019-10-17 |
2022-05-12 |
Ginkgo Bioworks, Inc. |
Adeno-associated viral vectors for treatment of Niemann-Pick disease type C
|
|
JP7665609B2
(ja)
|
2019-10-30 |
2025-04-21 |
デシベル セラピューティクス インコーポレイテッド |
オトフェリン二重ベクター系及びそれを含む感音難聴を治療するための組成物
|
|
WO2021089736A1
(en)
|
2019-11-06 |
2021-05-14 |
Association Institut De Myologie |
Combined therapy for muscular diseases
|
|
US20230270886A1
(en)
*
|
2019-11-28 |
2023-08-31 |
Regenxbio Inc. |
Microdystrophin gene therapy constructs and uses thereof
|
|
CA3174500A1
(en)
|
2020-04-01 |
2021-10-07 |
University Of Florida Research Foundation, Incorporated |
Dual aav-myo7a vectors with improved safety for the treatment of ush1b
|
|
TW202206447A
(zh)
|
2020-04-29 |
2022-02-16 |
美商必治妥美雅史谷比公司 |
具血影蛋白(spectrin)融合結構域之微型化肌肉萎縮蛋白及其用途
|
|
MX2023002016A
(es)
|
2020-08-19 |
2023-06-26 |
Sarepta Therapeutics Inc |
Vectores de virus adenoasociados para el tratamiento del sindrome de rett.
|
|
WO2022076750A2
(en)
|
2020-10-07 |
2022-04-14 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns or muscle delivery
|
|
AU2021369480B2
(en)
|
2020-10-28 |
2025-05-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding AAV2.5 vector
|
|
WO2022093769A1
(en)
|
2020-10-28 |
2022-05-05 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding aav2.5 vector
|
|
TW202242124A
(zh)
|
2021-01-14 |
2022-11-01 |
美商史崔德生物公司 |
靶向ｔ細胞之ａａｖ載體
|
|
US20240191251A1
(en)
|
2021-04-05 |
2024-06-13 |
Solid Biosciences Inc. |
Recombinant herpesvirales vector
|
|
CA3216491A1
(en)
|
2021-04-16 |
2022-10-20 |
Asklepios Biopharmaceutical, Inc. |
Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
|
|
US20240216543A1
(en)
*
|
2021-04-26 |
2024-07-04 |
Regenxbio Inc. |
Microdystrophin gene therapy administration for treatment of dystrophinopathies
|
|
US20240390522A1
(en)
*
|
2021-09-28 |
2024-11-28 |
University Of Florida Research Foundation, Incorporated |
Gene therapy for duchenne muscular dystrophy
|
|
EP4413018A1
(en)
|
2021-10-07 |
2024-08-14 |
RegenxBio Inc. |
Recombinant adeno-associated viruses for targeted delivery
|
|
CN115960946B
(zh)
*
|
2021-10-09 |
2026-02-13 |
中国科学院分子植物科学卓越创新中心 |
调节植物镁离子吸收和转运的方法
|
|
US12285497B2
(en)
|
2021-10-15 |
2025-04-29 |
Research Institute At Nationwide Children's Hospital |
Self-complementary adeno-associated virus vector and its use in treatment of muscular dystrophy
|
|
CN119233831A
(zh)
*
|
2022-01-17 |
2024-12-31 |
迪纳柯公司 |
用于与肌营养不良蛋白有关的心肌病的基因疗法组合物和治疗
|
|
EP4215614A1
(en)
|
2022-01-24 |
2023-07-26 |
Dynacure |
Combination therapy for dystrophin-related diseases
|
|
TW202342759A
(zh)
|
2022-02-04 |
2023-11-01 |
美商史崔德生物公司 |
重組腺相關病毒載體及其使用方法
|
|
WO2023212193A1
(en)
*
|
2022-04-27 |
2023-11-02 |
The Curators Of The University Of Missouri |
Micro-dystrophin for heart protection
|
|
WO2024124019A2
(en)
|
2022-12-07 |
2024-06-13 |
Ginkgo Bioworks, Inc. |
Aav vectors targeting hematopoietic stem cells
|
|
WO2024216244A2
(en)
|
2023-04-13 |
2024-10-17 |
Regenxbio Inc. |
Targeting aav capsids, methods of manufacturing and using same
|
|
WO2025017168A1
(en)
*
|
2023-07-19 |
2025-01-23 |
Genethon |
Novel optimized utrophin micro-genes
|
|
WO2026094009A1
(en)
*
|
2024-11-04 |
2026-05-07 |
Insmed Incorporated |
Compositions and methods for treating duchenne muscular dystrophy
|