|
SI2173888T1
(sl)
*
|
2007-07-26 |
2017-01-31 |
Uniqure Ip B.V. |
Bakulovirusni vektorji, ki vsebujejo ponavljajoča kodirna zaporedja z različnimi kodonskimi preferencami
|
|
GB0911870D0
(en)
|
2009-07-08 |
2009-08-19 |
Ucl Business Plc |
Optimised coding sequence and promoter
|
|
EP2545165B1
(en)
|
2010-03-11 |
2020-07-29 |
uniQure IP B.V. |
Mutated rep encoding sequences for use in aav production
|
|
WO2011122950A1
(en)
|
2010-04-01 |
2011-10-06 |
Amsterdam Molecular Therapeutics (Amt) Ip B.V. |
Monomeric duplex aav vectors
|
|
IT1400425B1
(it)
|
2010-06-08 |
2013-05-31 |
Amsterdam Molecular Therapeutics Bv |
Modified snrnas for use in therapy.
|
|
US20140155469A1
(en)
|
2011-04-19 |
2014-06-05 |
The Research Foundation Of State University Of New York |
Adeno-associated-virus rep sequences, vectors and viruses
|
|
GB201210357D0
(en)
|
2012-06-12 |
2012-07-25 |
Ucl Business Plc |
Factor VIII sequences
|
|
EA036394B1
(ru)
|
2013-10-24 |
2020-11-05 |
ЮНИКЬЮРЕ АйПи Б.В. |
Псевдотипированный вектор на основе аденоассоциированного вируса aav-5 для генной терапии неврологических заболеваний
|
|
FI3117005T3
(fi)
*
|
2014-03-10 |
2024-08-29 |
Uniqure Ip Bv |
Hyönteissoluissa tuotettuja lisää parannettuja aav-vektoreita
|
|
EP3151866B1
(en)
|
2014-06-09 |
2023-03-08 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
BR112017009497A2
(pt)
|
2014-11-05 |
2018-02-06 |
Voyager Therapeutics, Inc. |
polinucleotídeos de aadc para o tratamento da doença de parkinson
|
|
GB201420139D0
(en)
|
2014-11-12 |
2014-12-24 |
Ucl Business Plc |
Factor IX gene therapy
|
|
CA2967367C
(en)
|
2014-11-14 |
2023-05-16 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
US10570395B2
(en)
|
2014-11-14 |
2020-02-25 |
Voyager Therapeutics, Inc. |
Modulatory polynucleotides
|
|
JP6741345B2
(ja)
|
2014-11-28 |
2020-08-19 |
ユニキュアー アイピー ビー．ブイ． |
パルボウイルスビリオンを含む組成物におけるｄｎａ不純物
|
|
HK1245326A1
(zh)
|
2014-12-12 |
2018-08-24 |
Voyager Therapeutics, Inc. |
用於生产scaav的组合物和方法
|
|
US10174321B2
(en)
|
2014-12-24 |
2019-01-08 |
Uniqure Ip B.V. |
RNAI induced huntingtin gene suppression
|
|
AU2017254652B2
(en)
*
|
2016-04-21 |
2022-12-01 |
Virovek, Inc. |
AAV production in insect cells, methods and compositions therefor
|
|
WO2017189959A1
(en)
|
2016-04-29 |
2017-11-02 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
WO2017189964A2
(en)
|
2016-04-29 |
2017-11-02 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
RU2764587C2
(ru)
|
2016-05-18 |
2022-01-18 |
Вояджер Терапьютикс, Инк. |
Способы и композиции для лечения хореи гентингтона
|
|
JP7066635B2
(ja)
|
2016-05-18 |
2022-05-13 |
ボイジャー セラピューティクス インコーポレイテッド |
調節性ポリヌクレオチド
|
|
SG11201811603WA
(en)
|
2016-07-26 |
2019-02-27 |
Biomarin Pharm Inc |
Novel adeno-associated virus capsid proteins
|
|
EP3510161A4
(en)
|
2016-08-23 |
2020-04-22 |
Akouos, Inc. |
COMPOSITIONS AND METHODS FOR TREATING NON-AGE-ASSOCIATED HEARING DEFICIENCY IN A HUMAN SUBJECT
|
|
US11298041B2
(en)
|
2016-08-30 |
2022-04-12 |
The Regents Of The University Of California |
Methods for biomedical targeting and delivery and devices and systems for practicing the same
|
|
WO2018109207A1
(en)
|
2016-12-16 |
2018-06-21 |
Uniqure Ip B.V. |
Immunoadsorption
|
|
SG11201909868YA
(en)
|
2017-05-05 |
2019-11-28 |
Voyager Therapeutics Inc |
Compositions and methods of treating huntington's disease
|
|
EP3618839A4
(en)
|
2017-05-05 |
2021-06-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
HUE069232T2
(hu)
|
2017-07-10 |
2025-02-28 |
Uniqure Ip Bv |
Módok és eljárások AAV génterápiára emberekben
|
|
JP7229989B2
(ja)
|
2017-07-17 |
2023-02-28 |
ボイジャー セラピューティクス インコーポレイテッド |
軌道アレイガイドシステム
|
|
AU2018311069A1
(en)
|
2017-08-03 |
2020-02-20 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of AAV
|
|
EP3687582A4
(en)
|
2017-09-29 |
2021-07-14 |
Voyager Therapeutics, Inc. |
RESCUE OF CENTRAL AND PERIPHERAL NEUROLOGICAL PHENOTYPE OF FRIEDREICH ATAXIA BY INTRAVENOUS ADMINISTRATION
|
|
TW202413649A
(zh)
|
2017-10-16 |
2024-04-01 |
美商航海家醫療公司 |
肌萎縮性脊髓側索硬化症(als)之治療
|
|
US20200237799A1
(en)
|
2017-10-16 |
2020-07-30 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
AU2018394287B2
(en)
|
2017-12-29 |
2024-09-26 |
Uniqure Ip B.V. |
Modified viral vectors and methods of making and using the same
|
|
HRP20231126T1
(hr)
|
2018-01-17 |
2024-01-05 |
Meiragtx Uk Ii Limited |
Modificirani protein kapsida raav za gensku terapiju
|
|
GB201800903D0
(en)
|
2018-01-19 |
2018-03-07 |
Oxford Genetics Ltd |
Vectors
|
|
EP3793616A1
(en)
|
2018-05-15 |
2021-03-24 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
JP2021523914A
(ja)
|
2018-05-15 |
2021-09-09 |
ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
パーキンソン病を治療するための組成物および方法
|
|
EP3807404A1
(en)
|
2018-06-13 |
2021-04-21 |
Voyager Therapeutics, Inc. |
Engineered 5' untranslated regions (5' utr) for aav production
|
|
CA3103963A1
(en)
|
2018-07-02 |
2020-01-09 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis and disorders associated with the spinal cord
|
|
US20210355454A1
(en)
|
2018-07-24 |
2021-11-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
|
GB201813528D0
(en)
|
2018-08-20 |
2018-10-03 |
Ucl Business Plc |
Factor IX encoding nucleotides
|
|
US10842885B2
(en)
|
2018-08-20 |
2020-11-24 |
Ucl Business Ltd |
Factor IX encoding nucleotides
|
|
WO2020053258A1
(en)
|
2018-09-12 |
2020-03-19 |
Uniqure Ip B.V. |
Rnai induced c9orf72 suppression for the treatment of als/ftd
|
|
WO2020061418A1
(en)
*
|
2018-09-20 |
2020-03-26 |
Tallgrass Biologics L.L.C. |
Treatment and control of colony collapse disorder
|
|
CN109295172A
(zh)
*
|
2018-09-26 |
2019-02-01 |
浙江海洋大学 |
大黄鱼清道夫受体家族基因的密码子偏好性分析方法
|
|
EP3856762A1
(en)
|
2018-09-28 |
2021-08-04 |
Voyager Therapeutics, Inc. |
Frataxin expression constructs having engineered promoters and methods of use thereof
|
|
TW202035689A
(zh)
|
2018-10-04 |
2020-10-01 |
美商航海家醫療公司 |
測量病毒載體粒子的效價及強度之方法
|
|
AU2019354793A1
(en)
|
2018-10-05 |
2021-05-13 |
Voyager Therapeutics, Inc. |
Engineered nucleic acid constructs encoding AAV production proteins
|
|
US20210371470A1
(en)
|
2018-10-12 |
2021-12-02 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
WO2020081490A1
(en)
|
2018-10-15 |
2020-04-23 |
Voyager Therapeutics, Inc. |
EXPRESSION VECTORS FOR LARGE-SCALE PRODUCTION OF rAAV IN THE BACULOVIRUS/Sf9 SYSTEM
|
|
WO2020104480A1
(en)
|
2018-11-19 |
2020-05-28 |
Uniqure Biopharma B.V. |
Adeno-associated virus vectors for expressing fviii mimetics and uses thereof
|
|
AU2019385638A1
(en)
|
2018-11-19 |
2021-06-03 |
Uniqure Ip B.V. |
A companion diagnostic to monitor the effects of gene therapy
|
|
WO2020104295A1
(en)
|
2018-11-19 |
2020-05-28 |
Uniqure Ip B.V. |
Rnai induced reduction of ataxin-3 for the treatment of spinocerebellar ataxia type 3
|
|
CA3120177A1
(en)
|
2018-11-19 |
2020-05-28 |
Uniqure Ip B.V. |
Method and means to deliver mirna to target cells
|
|
SG11202107645RA
(en)
|
2019-01-18 |
2021-08-30 |
Voyager Therapeutics Inc |
Methods and systems for producing aav particles
|
|
TW202106879A
(zh)
|
2019-04-29 |
2021-02-16 |
美商航海家醫療公司 |
於生物反應器中生產經桿狀病毒感染之昆蟲細胞(biic)之系統及方法
|
|
US20220267797A1
(en)
|
2019-07-15 |
2022-08-25 |
Meiragtx Uk Ii Limited |
Modified AAV Capsid Proteins for Treatment of Arthritic Disease
|
|
WO2021030125A1
(en)
|
2019-08-09 |
2021-02-18 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
WO2021041375A1
(en)
*
|
2019-08-26 |
2021-03-04 |
Rootpath Genomics, Inc. |
Compositions and methods for producing adeno-associated viral vectors
|
|
EP4022070A1
(en)
|
2019-08-26 |
2022-07-06 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
EP4031148A1
(en)
|
2019-09-16 |
2022-07-27 |
uniQure IP B.V. |
Targeting misspliced transcripts in genetic disorders
|
|
TW202134440A
(zh)
*
|
2019-12-04 |
2021-09-16 |
美商聖加莫治療股份有限公司 |
用於生產重組aav之新穎組合物及方法
|
|
WO2021168362A1
(en)
|
2020-02-21 |
2021-08-26 |
Akouos, Inc. |
Compositions and methods for treating non-age-associated hearing impairment in a human subject
|
|
WO2021195491A2
(en)
*
|
2020-03-26 |
2021-09-30 |
Asklepios Biopharmaceutical, Inc. |
Inducible promoter for viral vector production
|
|
KR20220163950A
(ko)
*
|
2020-04-02 |
2022-12-12 |
유니큐어 바이오파마 비.브이. |
Aav 생산을 위한 이중 이기능성 벡터
|
|
AU2021249483A1
(en)
|
2020-04-02 |
2022-09-15 |
Uniqure Biopharma B.V. |
Novel cell line
|
|
JP2023521347A
(ja)
|
2020-04-07 |
2023-05-24 |
ユニキュアー アイピー ビー．ブイ． |
アンジオポエチン様３（ａｎｇｐｔｌ３）をサイレンシングするための遺伝子構築物及びその使用
|
|
WO2021211753A1
(en)
|
2020-04-15 |
2021-10-21 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
|
MX2023000815A
(es)
|
2020-07-27 |
2023-04-11 |
Voyager Therapeutics Inc |
Composiciones y metodos para el tratamiento de trastornos neurologicos relacionados con la deficiencia de glucosilceramidasa beta.
|
|
WO2022026410A2
(en)
|
2020-07-27 |
2022-02-03 |
Voyager Therapeutics, Inc |
Compositions and methods for the treatment of niemann-pick type c1 disease
|
|
EP4192514A1
(en)
|
2020-08-06 |
2023-06-14 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
US20240141377A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
US20240141378A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
CN115427561B
(zh)
|
2021-03-09 |
2024-06-04 |
辉大(上海)生物科技有限公司 |
工程化CRISPR/Cas13系统及其用途
|
|
WO2022214635A1
(en)
|
2021-04-08 |
2022-10-13 |
Stichting Vu |
Nucleic acid molecules for compensation of stxbp1 haploinsufficiency and their use in the treatment of stxbp1-related disorders
|
|
EP4347849A1
(en)
|
2021-06-02 |
2024-04-10 |
uniQure biopharma B.V. |
Adeno-associated virus vectors modified to bind high-density lipoprotein
|
|
EP4347798A2
(en)
|
2021-06-02 |
2024-04-10 |
uniQure biopharma B.V. |
Insect cell production of parvoviral vectors with modified capsid proteins
|
|
US20250382611A1
(en)
|
2021-06-21 |
2025-12-18 |
Uniqure Biopharma B.V. |
Gene constructs for silencing alpha-synuclein and uses thereof
|
|
EP4359010A1
(en)
|
2021-06-21 |
2024-05-01 |
uniQure biopharma B.V. |
Improved lysis procedures
|
|
WO2023283962A1
(en)
|
2021-07-16 |
2023-01-19 |
Huigene Therapeutics Co., Ltd. |
Modified aav capsid for gene therapy and methods thereof
|
|
KR20240021951A
(ko)
*
|
2021-07-28 |
2024-02-19 |
바이오마린 파머수티컬 인크. |
대규모 아데노-관련 바이러스 생산 시스템
|
|
WO2023025920A1
(en)
|
2021-08-26 |
2023-03-02 |
Uniqure Biopharma B.V. |
Insect cell-produced high potency aav vectors with cns-tropism
|
|
US20250049955A1
(en)
|
2021-11-17 |
2025-02-13 |
Voyager Therapeutics, Inc. |
Compositons and methods for the treatment of neurological disorders related to glucosylceramidase beta deficiency
|
|
WO2023147374A2
(en)
|
2022-01-25 |
2023-08-03 |
Voyager Therapeutics, Inc. |
Baculovirus expression system
|
|
CN114703203B
(zh)
*
|
2022-02-11 |
2024-08-06 |
上海渤因生物科技有限公司 |
杆状病毒载体及其用途
|
|
EP4508216A1
(en)
|
2022-04-12 |
2025-02-19 |
uniQure biopharma B.V. |
Nucleic acid regulation of snca
|
|
WO2023198662A1
(en)
|
2022-04-12 |
2023-10-19 |
Uniqure Biopharma B.V. |
Novel systems for nucleic acid regulation
|
|
WO2023198702A1
(en)
|
2022-04-12 |
2023-10-19 |
Uniqure Biopharma B.V. |
Nucleic acid regulation of c9orf72
|
|
JP2025513066A
(ja)
|
2022-04-12 |
2025-04-22 |
ユニキュアー バイオファーマ ビー．ブイ． |
Ａｐｏｅの核酸制御
|
|
WO2023240236A1
(en)
|
2022-06-10 |
2023-12-14 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of spinal muscular atrophy related disorders
|
|
WO2024054983A1
(en)
|
2022-09-08 |
2024-03-14 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
EP4644556A1
(en)
|
2022-12-28 |
2025-11-05 |
FUJIFILM Corporation |
Method for producing adeno-associated virus, and vector set
|
|
AU2023427408A1
(en)
|
2023-02-02 |
2025-09-04 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of neurological disorders related to glucosylceramidase beta deficiency
|
|
AU2024256392A1
(en)
|
2023-04-18 |
2025-10-23 |
Uniqure Biopharma B.V. |
Gene delivery vehicles comprising rna and antibodies
|
|
AU2024258047A1
(en)
|
2023-04-18 |
2025-10-23 |
Uniqure Biopharma B.V. |
Novel neurotropic adeno-associated virus capsids with detargeting of peripheral organs
|
|
AU2024258816A1
(en)
|
2023-04-18 |
2025-10-23 |
Uniqure Biopharma B.V. |
Generation of adeno-associated virus capsid libraries for insect cells
|
|
TW202449167A
(zh)
|
2023-04-26 |
2024-12-16 |
美商航海家醫療公司 |
用於治療肌肉萎縮性脊髓側索硬化症之組成物及方法
|
|
WO2024261220A1
(en)
|
2023-06-23 |
2024-12-26 |
Uniqure Biopharma B.V. |
Novel fragile x constructs
|
|
WO2025049993A1
(en)
|
2023-08-31 |
2025-03-06 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|
|
WO2025051805A1
(en)
|
2023-09-04 |
2025-03-13 |
Uniqure Biopharma B.V. |
Novel neurotropic recombinant adeno-associated virus particles
|
|
WO2025078602A1
(en)
|
2023-10-11 |
2025-04-17 |
Uniqure Biopharma B.V. |
Nucleic acid regulation of msh3 in repeat expansion disorders
|
|
WO2025078598A1
(en)
|
2023-10-11 |
2025-04-17 |
Uniqure Biopharma B.V. |
Novel nucleic acid regulation of huntingtin gene
|
|
WO2025078606A1
(en)
|
2023-10-11 |
2025-04-17 |
Uniqure Biopharma B.V. |
Further novel systems for nucleic acid regulation
|
|
WO2025114524A1
(en)
|
2023-11-30 |
2025-06-05 |
Uniqure Biopharma B.V. |
Formulations for viral drug products
|
|
WO2025171227A1
(en)
|
2024-02-08 |
2025-08-14 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|
|
WO2025219443A1
(en)
|
2024-04-19 |
2025-10-23 |
Uniqure Biopharma B.V. |
Nucleic acid for a1at regulation
|