JP2018509154A5 - - Google Patents
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- JP2018509154A5 JP2018509154A5 JP2017547425A JP2017547425A JP2018509154A5 JP 2018509154 A5 JP2018509154 A5 JP 2018509154A5 JP 2017547425 A JP2017547425 A JP 2017547425A JP 2017547425 A JP2017547425 A JP 2017547425A JP 2018509154 A5 JP2018509154 A5 JP 2018509154A5
- Authority
- JP
- Japan
- Prior art keywords
- vector
- nucleotide sequence
- mammal
- motomeko
- sequence encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562131661P | 2015-03-11 | 2015-03-11 | |
| US62/131,661 | 2015-03-11 | ||
| PCT/US2016/022072 WO2016145345A1 (en) | 2015-03-11 | 2016-03-11 | Rp2 and rpgr vectors for treating x-linked retinitis pigmentosa |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020167984A Division JP2021019611A (ja) | 2015-03-11 | 2020-10-02 | Ｘ連鎖性網膜色素変性症の治療のためのｒｐ２及びｒｐｇｒベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018509154A JP2018509154A (ja) | 2018-04-05 |
| JP2018509154A5 true JP2018509154A5 (enExample) | 2019-04-18 |
| JP6935049B2 JP6935049B2 (ja) | 2021-09-15 |
Family
ID=56879752
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017547425A Active JP6935049B2 (ja) | 2015-03-11 | 2016-03-11 | Ｘ連鎖性網膜色素変性症の治療のためのｒｐ２及びｒｐｇｒベクター |
| JP2020167984A Pending JP2021019611A (ja) | 2015-03-11 | 2020-10-02 | Ｘ連鎖性網膜色素変性症の治療のためのｒｐ２及びｒｐｇｒベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020167984A Pending JP2021019611A (ja) | 2015-03-11 | 2020-10-02 | Ｘ連鎖性網膜色素変性症の治療のためのｒｐ２及びｒｐｇｒベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10646588B2 (enExample) |
| EP (2) | EP3719134B1 (enExample) |
| JP (2) | JP6935049B2 (enExample) |
| AU (1) | AU2016228751B2 (enExample) |
| CA (1) | CA2979229A1 (enExample) |
| WO (1) | WO2016145345A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2979229A1 (en) | 2015-03-11 | 2016-09-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rp2 vectors for treating x-linked retinitis pigmentosa |
| SMT202400321T1 (it) * | 2017-11-15 | 2024-11-15 | Univ Michigan Regents | Vettori virali comprendenti regioni codificanti rdh12 e metodi di trattamento di distrofie retiniche |
| TW202028225A (zh) * | 2018-09-21 | 2020-08-01 | 英商夜星克有限公司 | 用於治療色素性視網膜炎之組合物及方法 |
| CA3131023A1 (en) * | 2019-02-22 | 2020-08-27 | Michael R. Volkert | Oxr1 gene therapy |
| KR20220049619A (ko) * | 2019-08-30 | 2022-04-21 | 베이롤 칼리지 오브 메드신 | 유전자 발현 조절 시스템 |
| WO2021178668A1 (en) * | 2020-03-04 | 2021-09-10 | University Of Massachusetts | Compositions and methods for modulating rpgr expression |
| EP4511496A4 (en) * | 2022-04-18 | 2026-06-24 | Abeona Therapeutics Inc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DOMINANT OPTIC ATROPHY AND X-RELATED RETINOSCHISISIS |
| CN117165596A (zh) * | 2022-05-27 | 2023-12-05 | 武汉纽福斯生物科技有限公司 | 编码rpgr的核酸及其应用 |
| WO2026119796A1 (en) * | 2024-12-05 | 2026-06-11 | Beacon Therapeutics Limited | Gene therapy vector |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998010086A1 (en) | 1996-09-06 | 1998-03-12 | Trustees Of The University Of Pennsylvania | Methods using cre-lox for production of recombinant adeno-associated viruses |
| EP2242840B1 (en) | 2008-01-29 | 2019-07-24 | Applied Genetic Technologies Corporation | Recombinant adeno-associated virus production using bhk cells in suspension |
| US20100081707A1 (en) * | 2008-02-21 | 2010-04-01 | Ali Robin R | Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea |
| CA2837322C (en) | 2011-05-26 | 2023-03-21 | University Of Washington | Cell and gene based methods to improve cardiac function |
| CN105120901A (zh) * | 2012-07-11 | 2015-12-02 | 宾夕法尼亚大学托管会 | Rpgr x染色体连锁视网膜退化的aav介导的基因治疗 |
| AU2014216160B2 (en) * | 2013-02-15 | 2017-03-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | AAV8 retinoschisin expression vector for treating X-linked retinoschisis |
| CN105209619B (zh) * | 2013-03-11 | 2018-10-12 | 泰莱托恩基金会 | miR-204和miR-211及其用途 |
| EP3132051B1 (en) * | 2014-04-15 | 2019-03-20 | Applied Genetic Technologies Corporation | Codon optimized nucleic acid encoding a retinitis pigmentosa gtpase regulator (rpgr) |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| GB201412011D0 (en) * | 2014-07-04 | 2014-08-20 | Ucl Business Plc | Treatments |
| SMT202000715T1 (it) * | 2014-07-24 | 2021-01-05 | Massachusetts Eye & Ear Infirmary | Terapia genica rpgr per la retinite pigmentosa |
| CA2979120A1 (en) * | 2015-03-03 | 2016-09-09 | Fondazione Telethon | Multiple aav vector system for expressing genes over 5 kilobases, comprising at least one degradation signal and uses thereof |
| CA2979229A1 (en) * | 2015-03-11 | 2016-09-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rp2 vectors for treating x-linked retinitis pigmentosa |
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2016
- 2016-03-11 CA CA2979229A patent/CA2979229A1/en active Pending
- 2016-03-11 EP EP20176667.2A patent/EP3719134B1/en active Active
- 2016-03-11 AU AU2016228751A patent/AU2016228751B2/en active Active
- 2016-03-11 US US15/556,746 patent/US10646588B2/en active Active
- 2016-03-11 JP JP2017547425A patent/JP6935049B2/ja active Active
- 2016-03-11 WO PCT/US2016/022072 patent/WO2016145345A1/en not_active Ceased
- 2016-03-11 EP EP16762623.3A patent/EP3268481B1/en active Active
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2020
- 2020-04-21 US US16/854,605 patent/US11617801B2/en active Active
- 2020-10-02 JP JP2020167984A patent/JP2021019611A/ja active Pending