|
HRP20100378T1
(hr)
|
2006-05-31 |
2010-08-31 |
Galapagos N.V. |
Spojevi triazolopirazina učinkoviti za tretman degenerativnih i upalnih bolesti
|
|
AR063706A1
(es)
*
|
2006-09-11 |
2009-02-11 |
Cgi Pharmaceuticals Inc |
Determinadas amidas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmaceuticas que las comprenden.
|
|
CL2008002793A1
(es)
|
2007-09-20 |
2009-09-04 |
Cgi Pharmaceuticals Inc |
Compuestos derivados de amidas sustituidas, inhibidores de la actividad de btk; composicion farmaceutica que los comprende; utiles en el tratamiento del cancer, trastornos oseos, enfermedades autoinmunes, entre otras
|
|
JP5587193B2
(ja)
*
|
2007-10-23 |
2014-09-10 |
エフ.ホフマン−ラ ロシュ アーゲー |
新規なキナーゼ阻害剤
|
|
US7683064B2
(en)
|
2008-02-05 |
2010-03-23 |
Roche Palo Alto Llc |
Inhibitors of Bruton's tyrosine kinase
|
|
CA2723237A1
(en)
*
|
2008-05-06 |
2009-11-12 |
Peter A. Blomgren |
Substituted amides, method of making, and use as btk inhibitors
|
|
PE20100851A1
(es)
|
2008-06-24 |
2011-01-31 |
Hoffmann La Roche |
PIRIDIN-2-ONAS Y PIRIDAZIN-3-ONAS SUSTITUIDAS COMO INHIBIDORES DE Btk
|
|
PL2300459T3
(pl)
*
|
2008-07-02 |
2013-10-31 |
Hoffmann La Roche |
Nowe fenylopirazynony jako inhibitory kinazy
|
|
CA2726460C
(en)
*
|
2008-07-15 |
2017-02-21 |
F. Hoffmann-La Roche Ag |
Novel phenyl-imidazopyridines and pyridazines
|
|
EP2307418B1
(en)
*
|
2008-07-18 |
2014-03-12 |
F.Hoffmann-La Roche Ag |
Novel phenylimidazopyrazines
|
|
WO2010011837A1
(en)
|
2008-07-24 |
2010-01-28 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds useful as kinase modulators
|
|
WO2010068806A1
(en)
*
|
2008-12-10 |
2010-06-17 |
Cgi Pharmaceuticals, Inc. |
Amide derivatives as btk inhibitors in the treatment of allergic, autoimmune and inflammatory disorders as well as cancer
|
|
ES2443948T3
(es)
|
2008-12-19 |
2014-02-21 |
Bristol-Myers Squibb Company |
Compuestos de carbazol carboxamida útiles como inhibidores de quinasas
|
|
CN102458402B
(zh)
|
2009-06-12 |
2013-10-02 |
百时美施贵宝公司 |
用作激酶调节剂的烟酰胺化合物
|
|
WO2011019780A1
(en)
|
2009-08-11 |
2011-02-17 |
Bristol-Myers Squibb Company |
Azaindazoles as btk kinase modulators and use thereof
|
|
TWI557127B
(zh)
|
2009-09-04 |
2016-11-11 |
百健Ma公司 |
布魯頓氏酪胺酸激酶抑制劑
|
|
US8685969B2
(en)
|
2010-06-16 |
2014-04-01 |
Bristol-Myers Squibb Company |
Carboline carboxamide compounds useful as kinase inhibitors
|
|
AR082590A1
(es)
|
2010-08-12 |
2012-12-19 |
Hoffmann La Roche |
Inhibidores de la tirosina-quinasa de bruton
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
WO2012135631A1
(en)
|
2011-03-30 |
2012-10-04 |
Arrien Pharmaeuticals Llc |
Substituted 5-(pyrazin-2-yl)-1h-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors
|
|
ES2548414T3
(es)
|
2011-07-08 |
2015-10-16 |
Novartis Ag |
Novedosos derivados de pirrolo pirimidina
|
|
WO2013161848A1
(ja)
*
|
2012-04-27 |
2013-10-31 |
カルナバイオサイエンス株式会社 |
新規1,2,4-トリアジン誘導体
|
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
AR091273A1
(es)
*
|
2012-06-08 |
2015-01-21 |
Biogen Idec Inc |
Inhibidores de pirimidinil tirosina quinasa
|
|
HK1208681A1
(en)
|
2012-06-12 |
2016-03-11 |
Abbvie Inc. |
Pyridinone and pyridazinone derivatives
|
|
CA2876689C
(en)
|
2012-06-13 |
2022-04-26 |
Incyte Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
HK1206073A1
(en)
|
2012-07-24 |
2015-12-31 |
药品循环有限责任公司 |
Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
WO2014108820A1
(en)
*
|
2013-01-08 |
2014-07-17 |
Aurigene Discovery Technologies Limited |
Substituted 2-pyrazinone derivatives as kinase inhibitors
|
|
WO2014125410A1
(en)
*
|
2013-02-12 |
2014-08-21 |
Aurigene Discovery Technologies Limited |
N-substituted heterocyclic derivatives as kinase inhibitors
|
|
PH12015502383B1
(en)
|
2013-04-19 |
2023-02-03 |
Incyte Holdings Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
PL2989106T3
(pl)
|
2013-04-25 |
2017-08-31 |
Beigene, Ltd. |
Połączone związki heterocykliczne jako inhibitory kinazy białkowej
|
|
AR096721A1
(es)
|
2013-06-25 |
2016-01-27 |
Bristol Myers Squibb Co |
Compuestos de tetrahidrocarbazol y carbazol carboxamida sustituidos
|
|
KR102345381B1
(ko)
|
2013-06-25 |
2021-12-29 |
브리스톨-마이어스 스큅 컴퍼니 |
키나제 억제제로서 유용한 카르바졸 카르복스아미드 화합물
|
|
SMT202300039T1
(it)
|
2013-09-13 |
2023-03-17 |
Beigene Switzerland Gmbh |
Anticorpi anti-pd1 e loro uso come terapia e per diagnostica
|
|
JP2016535764A
(ja)
*
|
2013-10-04 |
2016-11-17 |
ビヨンド オンコロジー ファーマシューティカル エルエルシー |
ブルトンのチロシンキナーゼの阻害剤
|
|
US9512084B2
(en)
|
2013-11-29 |
2016-12-06 |
Novartis Ag |
Amino pyrimidine derivatives
|
|
AU2014360446A1
(en)
|
2013-12-05 |
2016-06-09 |
Pharmacyclics, Llc |
Inhibitors of Bruton's tyrosine kinase
|
|
CN105793251B
(zh)
*
|
2013-12-05 |
2018-10-12 |
豪夫迈·罗氏有限公司 |
具有亲电子官能性的杂芳基吡啶酮和氮杂-吡啶酮化合物
|
|
TWI726608B
(zh)
|
2014-07-03 |
2021-05-01 |
英屬開曼群島商百濟神州有限公司 |
抗pd-l1抗體及其作為治療及診斷之用途
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
TWI676618B
(zh)
|
2014-10-24 |
2019-11-11 |
美商必治妥美雅史谷比公司 |
三環化合物
|
|
CN107108555B
(zh)
|
2014-10-24 |
2020-12-01 |
百时美施贵宝公司 |
三环阻转异构体化合物
|
|
MX393057B
(es)
|
2014-10-24 |
2025-03-24 |
Bristol Myers Squibb Co |
Compuestos de indol carboxamida útiles como inhibidores de cinasas.
|
|
CA2976790C
(en)
|
2015-02-20 |
2024-02-27 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
US9580423B2
(en)
|
2015-02-20 |
2017-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
US20170107216A1
(en)
|
2015-10-19 |
2017-04-20 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
MD3377488T2
(ro)
|
2015-11-19 |
2023-02-28 |
Incyte Corp |
Compuși heterociclici ca imunomodulatori
|
|
ES2916874T3
(es)
|
2015-12-17 |
2022-07-06 |
Incyte Corp |
Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1
|
|
CA3009474A1
(en)
|
2015-12-22 |
2017-06-29 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
CN107033069B
(zh)
*
|
2016-02-04 |
2022-03-04 |
中国科学院合肥物质科学研究院 |
一种新型布鲁顿酪氨酸激酶不可逆抑制剂
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
EP3464279B1
(en)
|
2016-05-26 |
2021-11-24 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
SG11201811414TA
(en)
|
2016-06-20 |
2019-01-30 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
WO2018007885A1
(en)
|
2016-07-05 |
2018-01-11 |
Beigene, Ltd. |
COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER
|
|
MA45669A
(fr)
|
2016-07-14 |
2019-05-22 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
CA3031443A1
(en)
|
2016-07-21 |
2018-01-25 |
Biogen Ma Inc. |
Succinate of pyrimidinyl derivatives and solid forms thereof as bruton's tyrosine kinase inhibitors
|
|
IL293319B1
(en)
|
2016-08-16 |
2026-01-01 |
Beone Medicines Ltd |
Crystal structure of s)–7–(1–acryloylpiperidin–4–yl)–2–(4–)phenoxyphenyl)–4,5,6,7–tetra–hydropyrazolo(1,5–a)pyrimidine–3–carboxamide, methods of preparation and uses thereof
|
|
CN110087680B
(zh)
|
2016-08-19 |
2024-03-19 |
百济神州有限公司 |
使用包含btk抑制剂的组合产品治疗癌症
|
|
US20180057486A1
(en)
|
2016-08-29 |
2018-03-01 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
CN109982687A
(zh)
|
2016-09-19 |
2019-07-05 |
梅制药公司 |
联合疗法
|
|
WO2018119236A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Triazolo[1,5-a]pyridine derivatives as immunomodulators
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
US10308644B2
(en)
|
2016-12-22 |
2019-06-04 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2018119221A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
EP4223369A1
(en)
|
2016-12-22 |
2023-08-09 |
Incyte Corporation |
Immunomodulator compounds and methods of use
|
|
EP3573989A4
(en)
|
2017-01-25 |
2020-11-18 |
Beigene, Ltd. |
CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
EP3645569A4
(en)
|
2017-06-26 |
2021-03-24 |
BeiGene, Ltd. |
IMMUNOTHERAPY FOR LIVER CELL CARCINOMA
|
|
WO2019034009A1
(en)
|
2017-08-12 |
2019-02-21 |
Beigene, Ltd. |
BTK INHIBITOR WITH ENHANCED DOUBLE SELECTIVITY
|
|
US11786529B2
(en)
|
2017-11-29 |
2023-10-17 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors
|
|
KR102708177B1
(ko)
|
2018-01-31 |
2024-09-23 |
데시페라 파마슈티칼스, 엘엘씨. |
위장관 기질 종양의 치료를 위한 병용 요법
|
|
CN118903436A
(zh)
|
2018-01-31 |
2024-11-08 |
德西费拉制药有限责任公司 |
治疗肥大细胞增多症的组合疗法
|
|
SMT202300065T1
(it)
|
2018-03-30 |
2023-05-12 |
Incyte Corp |
Composti eterociclici come immunomodulatori
|
|
KR102956194B1
(ko)
|
2018-05-04 |
2026-04-23 |
인사이트 코포레이션 |
Fgfr 억제제의 염
|
|
RS66310B1
(sr)
|
2018-05-04 |
2025-01-31 |
Incyte Corp |
Čvrsti oblici inhibitora fgfr i procesi za njegovu pripremu
|
|
CN112752756B
(zh)
|
2018-05-11 |
2024-06-25 |
因赛特公司 |
作为PD-L1免疫调节剂的四氢-咪唑并[4,5-c]吡啶衍生物
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
IL330104A
(en)
|
2019-03-11 |
2026-08-01 |
Deciphera Pharmaceuticals Llc |
Crystalline forms of rifatinib
|
|
EP3981399A4
(en)
|
2019-06-10 |
2023-05-31 |
BeiGene Switzerland GmbH |
ORAL SOLID TABLET WITH A TYROSINE KINAS INHIBITOR AND METHOD OF MANUFACTURE THEREOF
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
TW202115059A
(zh)
|
2019-08-09 |
2021-04-16 |
美商英塞特公司 |
Pd—1/pd—l1抑制劑之鹽
|
|
HRP20260411T1
(hr)
|
2019-08-12 |
2026-05-08 |
Deciphera Pharmaceuticals, Llc |
Ripretinib za liječenje gastrointestinalnih stromalnih tumora
|
|
JP7559059B2
(ja)
|
2019-09-30 |
2024-10-01 |
インサイト・コーポレイション |
免疫調節剤としてのピリド[3,2-d]ピリミジン化合物
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
EP4058461A1
(en)
|
2019-11-11 |
2022-09-21 |
Incyte Corporation |
Salts and crystalline forms of a pd-1/pd-l1 inhibitor
|
|
WO2021113479A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
MX2022006691A
(es)
|
2019-12-04 |
2022-09-19 |
Incyte Corp |
Derivados de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr).
|
|
FI4084779T3
(fi)
|
2019-12-30 |
2024-12-16 |
Deciphera Pharmaceuticals Llc |
1-(4-bromi-5-(1-etyyli-7-(metyyliamino)-2-okso-1,2-dihydro-1,6-naftyridin-3-yyli)-2-fluorifenyyli)-3-fenyyliurean koostumuksia
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
US11760756B2
(en)
|
2020-11-06 |
2023-09-19 |
Incyte Corporation |
Crystalline form of a PD-1/PD-L1 inhibitor
|
|
IL302590A
(en)
|
2020-11-06 |
2023-07-01 |
Incyte Corp |
Process for preparing PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為fgfr抑制劑之三環雜環
|
|
US11786531B1
(en)
|
2022-06-08 |
2023-10-17 |
Beigene Switzerland Gmbh |
Methods of treating B-cell proliferative disorder
|
|
US11779572B1
(en)
|
2022-09-02 |
2023-10-10 |
Deciphera Pharmaceuticals, Llc |
Methods of treating gastrointestinal stromal tumors
|