JP2010501598A5 - - Google Patents
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- Publication number
- JP2010501598A5 JP2010501598A5 JP2009525881A JP2009525881A JP2010501598A5 JP 2010501598 A5 JP2010501598 A5 JP 2010501598A5 JP 2009525881 A JP2009525881 A JP 2009525881A JP 2009525881 A JP2009525881 A JP 2009525881A JP 2010501598 A5 JP2010501598 A5 JP 2010501598A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- disease
- nhch
- interfering substituent
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C[C@]1OC2SC(*)=NC2[C@@](*)[C@@]1O Chemical compound *C[C@]1OC2SC(*)=NC2[C@@](*)[C@@]1O 0.000 description 2
- SJOFQKYWIQVOLP-QJVVIPRHSA-N CCNC(SC(CC12)OC(C3)(C3O)[C@H]3O)=N[C@H]1C2C3O Chemical compound CCNC(SC(CC12)OC(C3)(C3O)[C@H]3O)=N[C@H]1C2C3O SJOFQKYWIQVOLP-QJVVIPRHSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84119606P | 2006-08-31 | 2006-08-31 | |
| US60/841,196 | 2006-08-31 | ||
| US89566307P | 2007-03-19 | 2007-03-19 | |
| US60/895,663 | 2007-03-19 | ||
| PCT/CA2007/001554 WO2008025170A1 (en) | 2006-08-31 | 2007-08-31 | Selective glycosidase inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013123917A Division JP5771237B2 (ja) | 2006-08-31 | 2013-06-12 | 選択的グリコシダーゼ阻害剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010501598A JP2010501598A (ja) | 2010-01-21 |
| JP2010501598A5 true JP2010501598A5 (enExample) | 2010-10-21 |
| JP5380293B2 JP5380293B2 (ja) | 2014-01-08 |
Family
ID=39135489
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009525881A Expired - Fee Related JP5380293B2 (ja) | 2006-08-31 | 2007-08-31 | 選択的グリコシダーゼ阻害剤およびその使用 |
| JP2013123917A Expired - Fee Related JP5771237B2 (ja) | 2006-08-31 | 2013-06-12 | 選択的グリコシダーゼ阻害剤およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013123917A Expired - Fee Related JP5771237B2 (ja) | 2006-08-31 | 2013-06-12 | 選択的グリコシダーゼ阻害剤およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8334310B2 (enExample) |
| EP (2) | EP2057171A4 (enExample) |
| JP (2) | JP5380293B2 (enExample) |
| AU (1) | AU2007291870B2 (enExample) |
| CA (1) | CA2661582C (enExample) |
| WO (1) | WO2008025170A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006220187B2 (en) * | 2005-03-01 | 2012-11-08 | Simon Fraser University | Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof |
| EP2057171A4 (en) | 2006-08-31 | 2010-04-21 | Univ Fraser Simon | SELECTIVE GLYCOSIDASE INHIBITORS AND APPLICATIONS THEREOF |
| JP5687194B2 (ja) * | 2008-08-01 | 2015-03-18 | サイモン フレイザー ユニバーシティ | 選択的グリコシダーゼインヒビターおよびその使用 |
| WO2010012106A1 (en) | 2008-08-01 | 2010-02-04 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| US9120781B2 (en) | 2010-05-11 | 2015-09-01 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| WO2012014786A1 (en) * | 2010-07-30 | 2012-02-02 | Semiconductor Energy Laboratory Co., Ltd. | Semicondcutor device and manufacturing method thereof |
| TW201249848A (en) | 2010-11-08 | 2012-12-16 | Merck Sharp & Dohme | Selective glycosidase inhibitors and uses thereof |
| WO2012061972A1 (en) * | 2010-11-08 | 2012-05-18 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2012061927A1 (en) | 2010-11-08 | 2012-05-18 | Alectos Therapeutics, Inc. | Selective glycosidase inhibitors and uses thereof |
| US8901087B2 (en) | 2010-11-08 | 2014-12-02 | Merck Sharp & Dohme Corp. | Selective glycosidase inhibitors and uses thereof |
| BR112013016179A2 (pt) * | 2010-12-23 | 2018-07-10 | Alectos Therapeutics Inc | inibidores seletivos da glicosidase e usos dos mesmos. |
| WO2012126091A1 (en) * | 2011-03-24 | 2012-09-27 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| US9718854B2 (en) | 2011-03-31 | 2017-08-01 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2012129802A1 (en) * | 2011-03-31 | 2012-10-04 | Alectos Therapeutics Inc. | Pyrano[3,2-d]thiazol derivatives and uses as selective glycosidase inhibitors thereof |
| MX364602B (es) * | 2011-06-27 | 2019-05-02 | Alectos Therapeutics Inc | Inhibidores selectivos de glicosidasa y usos de los mismos. |
| WO2013000086A1 (en) * | 2011-06-27 | 2013-01-03 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2013000085A1 (en) | 2011-06-27 | 2013-01-03 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| EP2744338B1 (en) * | 2011-08-18 | 2016-04-27 | Merck Sharp & Dohme Corp. | Selective glycosidase inhibitors and uses thereof |
| US8884023B2 (en) | 2011-08-25 | 2014-11-11 | Merck Patent Gmbh | Pyrano [3,2-D][1,3]thiazole as glycosidase inhibitors |
| WO2013114371A1 (en) | 2012-02-01 | 2013-08-08 | Protalix Ltd. | Dry powder formulations of dnase i |
| WO2013166654A1 (en) * | 2012-05-08 | 2013-11-14 | Merck Sharp & Dohme Corp. | Permeable glycosidase inhibitors and uses thereof |
| CN104395323B (zh) * | 2012-05-08 | 2017-08-01 | 默沙东公司 | 可透过性糖苷酶抑制剂及其用途 |
| EP2890676B1 (en) | 2012-08-31 | 2018-12-05 | Alectos Therapeutics Inc. | Glycosidase inhibitors and uses thereof |
| EP2890675A4 (en) | 2012-08-31 | 2016-01-13 | Alectos Therapeutics Inc | GLYCOSIDASE INHIBITORS AND USES THEREOF |
| EP2914604A4 (en) | 2012-10-31 | 2016-07-20 | Alectos Therapeutics Inc | GLYCOSIDASE INHIBITORS AND USES THEREOF |
| WO2014100934A1 (en) * | 2012-12-24 | 2014-07-03 | Merck Sharp & Dohme Corp. | Glycosidase inhibitors and uses thereof |
| EP2964668B1 (en) | 2013-03-06 | 2019-11-27 | Protalix Ltd. | Tnf alpha inhibitor polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same |
| WO2014159234A1 (en) | 2013-03-14 | 2014-10-02 | Merck Patent Gmbh | Glycosidase inhibitors |
| CA2939380A1 (en) * | 2014-02-12 | 2015-08-20 | Amicus Therapeutics, Inc. | Sugar derivatives comprising sulfur-containing moieties and methods of making same and methods of using the same for the treatment of mps iiic |
| US10899784B2 (en) | 2014-08-15 | 2021-01-26 | The Johns Hopkins University | Use of UAP inhibitors to inhibit flux through the hexosamine biosynthetic pathway |
| MX381417B (es) | 2014-08-28 | 2025-03-12 | Asceneuron Sa | Inhibidores de glucosidasa. |
| JPWO2016056204A1 (ja) * | 2014-10-10 | 2017-07-13 | 株式会社Ｊｏｌｅｄ | 薄膜トランジスタ基板、薄膜トランジスタ基板の製造方法、及び、表示パネル |
| ES2809728T3 (es) | 2015-06-24 | 2021-03-05 | Hoffmann La Roche | Anticuerpos anti-tau(pS422) humanizados y procedimientos de uso |
| JP2019506430A (ja) | 2016-02-25 | 2019-03-07 | エースニューロン・ソシエテ・アノニム | グリコシダーゼ阻害剤 |
| JP6971999B2 (ja) | 2016-02-25 | 2021-11-24 | エースニューロン・ソシエテ・アノニム | ピペラジン誘導体の酸付加塩 |
| CN108884077A (zh) | 2016-02-25 | 2018-11-23 | 阿森纽荣股份公司 | 糖苷酶抑制剂 |
| US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
| AU2017400271B2 (en) | 2017-02-24 | 2020-09-24 | Asceneuron S.A. | Sulfoximine glycosidase inhibitors |
| US11458140B2 (en) | 2017-08-24 | 2022-10-04 | Asceneuron Sa | Annulated glycosidase inhibitors |
| US11213525B2 (en) | 2017-08-24 | 2022-01-04 | Asceneuron Sa | Linear glycosidase inhibitors |
| US11795165B2 (en) | 2018-08-22 | 2023-10-24 | Asceneuron Sa | Tetrahydro-benzoazepine glycosidase inhibitors |
| WO2020039029A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Spiro compounds as glycosidase inhibitors |
| CA3110032A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S.A. | Succinate and fumarate acid addition salts of piperazine derivatives |
| US12016852B2 (en) | 2018-08-22 | 2024-06-25 | Asceneuron Sa | Pyrrolidine glycosidase inhibitors |
| US20220143042A1 (en) | 2019-02-22 | 2022-05-12 | Asceneuron Sa | Fused glycosidase inhibitors |
| EP4366737A1 (en) | 2021-07-05 | 2024-05-15 | Asceneuron SA | Medicaments comprising glycosidase inhibitors |
| WO2024083820A1 (en) | 2022-10-18 | 2024-04-25 | Institut National de la Santé et de la Recherche Médicale | Method and composition for determining the level of o-glcnacylation in horses |
| WO2025131275A1 (en) | 2023-12-20 | 2025-06-26 | Asceneuron Sa | (2-(4-(1-(benzo[d]thiazol-5-yl)ethyl)piperazin-1 -yl)pyrimidin-5-yl)(imino)(methyl)-lamda6-sulfanone for use in the treatment of colitis, parkinson disease, tauopathy, als and alzheimer's disease |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS423200Y1 (enExample) | 1964-02-21 | 1967-02-24 | ||
| JPH01180894A (ja) | 1988-01-07 | 1989-07-18 | Wako Pure Chem Ind Ltd | アミノ糖誘導体の新規な製造法 |
| JPH023200A (ja) | 1988-06-10 | 1990-01-08 | Mitsubishi Electric Corp | 半導体集積回路装置のテスト回路 |
| JPH07316178A (ja) | 1994-05-25 | 1995-12-05 | Sankyo Co Ltd | 糖アミノオキサゾリン類 |
| JPH09132585A (ja) | 1995-11-10 | 1997-05-20 | Shin Etsu Chem Co Ltd | 新規アミノ糖及びキトオリゴ糖又はその類似オリゴ糖の製造方法 |
| WO2000068194A1 (en) | 1999-05-11 | 2000-11-16 | The Scripps Research Institute | Iminocyclitol inhibitors of hexoaminidase and glycosidase |
| US6774140B1 (en) | 1999-05-11 | 2004-08-10 | The Scripps Research Institute | Iminocyclitol inhibitors of hexoaminidase and glycosidase |
| JP4233262B2 (ja) | 2001-03-14 | 2009-03-04 | 生化学工業株式会社 | カルバ糖アミン誘導体及びそれを用いるグリコシダーゼ阻害剤 |
| EP1371733B1 (en) | 2001-03-14 | 2011-05-11 | Denki Kagaku Kogyo Kabushiki Kaisha | Process for producing hyaluronic acid or its derivative |
| JP4866515B2 (ja) | 2001-07-02 | 2012-02-01 | 生化学工業株式会社 | 糖オキサゾリン誘導体の製造方法 |
| WO2004103368A1 (en) | 2003-05-22 | 2004-12-02 | The Hospital For Sick Children | Treatment of tay sachs or sandhoff diseases by enhancing hexosaminidase activity |
| CN1548053A (zh) | 2003-05-23 | 2004-11-24 | 华晶基因技术有限公司 | 黄芩甙作为治疗焦虑症的药物的新用途 |
| JP2007518814A (ja) | 2004-01-20 | 2007-07-12 | ザ・スクリップス・リサーチ・インスティテュート | グリコシダーゼ阻害剤によるほ乳類での変性軟骨症の治療 |
| WO2006016904A2 (en) | 2004-04-14 | 2006-02-16 | Uab Research Foundation | Activators of hexosamine biosynthesis as inhibitors of injury induced by ischemia or hemorrhagic shock |
| AU2006220187B2 (en) | 2005-03-01 | 2012-11-08 | Simon Fraser University | Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof |
| EP2057171A4 (en) | 2006-08-31 | 2010-04-21 | Univ Fraser Simon | SELECTIVE GLYCOSIDASE INHIBITORS AND APPLICATIONS THEREOF |
| WO2010012106A1 (en) | 2008-08-01 | 2010-02-04 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| JP5687194B2 (ja) | 2008-08-01 | 2015-03-18 | サイモン フレイザー ユニバーシティ | 選択的グリコシダーゼインヒビターおよびその使用 |
| JP2012502884A (ja) | 2008-09-16 | 2012-02-02 | サイモン フレイザー ユニバーシティ | 選択的グリコシダーゼ阻害剤およびその使用 |
| US9120781B2 (en) | 2010-05-11 | 2015-09-01 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| WO2012061972A1 (en) | 2010-11-08 | 2012-05-18 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2012061927A1 (en) | 2010-11-08 | 2012-05-18 | Alectos Therapeutics, Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2012061971A1 (en) | 2010-11-08 | 2012-05-18 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| BR112013016179A2 (pt) | 2010-12-23 | 2018-07-10 | Alectos Therapeutics Inc | inibidores seletivos da glicosidase e usos dos mesmos. |
| WO2012126091A1 (en) | 2011-03-24 | 2012-09-27 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| US9718854B2 (en) | 2011-03-31 | 2017-08-01 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| MX364602B (es) | 2011-06-27 | 2019-05-02 | Alectos Therapeutics Inc | Inhibidores selectivos de glicosidasa y usos de los mismos. |
| WO2013000085A1 (en) | 2011-06-27 | 2013-01-03 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| WO2013000086A1 (en) | 2011-06-27 | 2013-01-03 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
-
2007
- 2007-08-31 EP EP07800577A patent/EP2057171A4/en not_active Withdrawn
- 2007-08-31 US US12/438,882 patent/US8334310B2/en not_active Expired - Fee Related
- 2007-08-31 WO PCT/CA2007/001554 patent/WO2008025170A1/en not_active Ceased
- 2007-08-31 CA CA2661582A patent/CA2661582C/en not_active Expired - Fee Related
- 2007-08-31 EP EP11157096.6A patent/EP2322529B1/en not_active Not-in-force
- 2007-08-31 AU AU2007291870A patent/AU2007291870B2/en not_active Ceased
- 2007-08-31 JP JP2009525881A patent/JP5380293B2/ja not_active Expired - Fee Related
-
2012
- 2012-08-22 US US13/591,927 patent/US8962664B2/en not_active Expired - Fee Related
-
2013
- 2013-06-12 JP JP2013123917A patent/JP5771237B2/ja not_active Expired - Fee Related
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