|
IL147037A0
(en)
*
|
1999-07-27 |
2002-08-14 |
Phylos Inc |
Peptide acceptor ligation methods
|
|
CA2397091A1
(en)
|
2000-01-11 |
2001-07-19 |
Markus Schweitzer |
Biomolecules having multiple attachment moieties for binding to a substrate surface
|
|
AU2001262152A1
(en)
*
|
2000-03-31 |
2001-10-08 |
Memorec Stoffel Gmbh |
Method for extracting nucleic acids
|
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
|
US7410761B2
(en)
*
|
2000-05-19 |
2008-08-12 |
Proteonova, Inc. |
System for rapid identification and selection of nucleic acids and polypeptides, and method thereof
|
|
WO2005072087A2
(en)
*
|
2003-12-12 |
2005-08-11 |
Proteonova, Inc. |
System and methods for nucleic acid and polypeptide selection
|
|
US6962781B1
(en)
|
2000-05-19 |
2005-11-08 |
Proteonova, Inc. |
In vitro evolution of nucleic acids and encoded polypeptide
|
|
WO2003044194A1
(en)
*
|
2001-11-16 |
2003-05-30 |
Proteonova, Inc. |
Selection and evolution of nucleic acids and polypeptides
|
|
US7129229B2
(en)
|
2000-08-11 |
2006-10-31 |
Nanogen Recognomics Gmbh |
Hydrazide building blocks and hydrazide modified biomolecules
|
|
EP1309730B1
(en)
*
|
2000-08-11 |
2008-11-26 |
Nanogen Recognomics GmbH |
New hydrazide building blocks and hydrazide modified biomolecules
|
|
JP4963142B2
(ja)
*
|
2000-12-14 |
2012-06-27 |
学校法人慶應義塾 |
遺伝子型と表現型の対応付け分子とその構成要素、および対応付け分子の製造方法と利用方法
|
|
EP1401850A1
(en)
*
|
2001-06-20 |
2004-03-31 |
Nuevolution A/S |
Nucleoside derivatives for library preparation
|
|
US20060234231A1
(en)
*
|
2001-06-20 |
2006-10-19 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
|
US6893822B2
(en)
|
2001-07-19 |
2005-05-17 |
Nanogen Recognomics Gmbh |
Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
|
|
WO2003012146A1
(en)
*
|
2001-07-31 |
2003-02-13 |
Phylos, Inc. |
Modular assembly of nucleic acid-protein fusion multimers
|
|
DE10147074A1
(de)
*
|
2001-09-25 |
2003-05-08 |
Beru Ag |
Verfahren zum Betreiben einer aus mehreren Heizelementen bestehenden mehrstufigen elektrischen Heizung
|
|
US7125669B2
(en)
*
|
2001-11-27 |
2006-10-24 |
Compound Therapeutics, Inc. |
Solid-phase immobilization of proteins and peptides
|
|
DE20200926U1
(de)
*
|
2002-01-23 |
2002-04-18 |
Hegenscheidt-MFD GmbH & Co. KG, 41812 Erkelenz |
Festwalzgerät einer Festwalzmaschine für Kurbelwellen
|
|
US20050247001A1
(en)
*
|
2002-03-15 |
2005-11-10 |
Nuevolution A/S |
Building block forming a c-c or a c-hetero atom bond uponreaction
|
|
US10731151B2
(en)
|
2002-03-15 |
2020-08-04 |
Nuevolution A/S |
Method for synthesising templated molecules
|
|
AU2003218630A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block capable of functional entity transfer to nucleophil
|
|
DE60324778D1
(de)
*
|
2002-03-15 |
2009-01-02 |
Nuevolution As |
Eine verbesserte methode zur synthese von matritzenabhängigen molekülen
|
|
US20050221318A1
(en)
*
|
2002-03-15 |
2005-10-06 |
Gouliaev Alex H |
Building block forming a c-c bond upon reaction
|
|
WO2004013070A2
(en)
*
|
2002-08-01 |
2004-02-12 |
Nuevolution A/S |
Multi-step synthesis of templated molecules
|
|
WO2004015075A2
(en)
*
|
2002-08-08 |
2004-02-19 |
Dharmacon, Inc. |
Short interfering rnas having a hairpin structure containing a non-nucleotide loop
|
|
DK3299463T3
(da)
|
2002-10-30 |
2020-12-07 |
Nuevolution As |
Enzymatisk kodning
|
|
ATE450609T1
(de)
|
2002-12-19 |
2009-12-15 |
Nuevolution As |
Durch quasizufallsstrukturen und funktionen geführte synthesemethode
|
|
US20070026397A1
(en)
*
|
2003-02-21 |
2007-02-01 |
Nuevolution A/S |
Method for producing second-generation library
|
|
EP1597394A2
(en)
*
|
2003-02-21 |
2005-11-23 |
Nuevolution A/S |
A method for obtaining structural information about an encoded molecule
|
|
US7915201B2
(en)
*
|
2003-03-20 |
2011-03-29 |
Nuevolution A/S |
Ligational encoding of small molecules
|
|
WO2004110964A2
(en)
*
|
2003-06-16 |
2004-12-23 |
Nuevolution A/S |
Encoded molecules by translation (emt)
|
|
WO2005074417A2
(en)
*
|
2003-09-03 |
2005-08-18 |
Salk Institute For Biological Studies |
Multiple antigen detection assays and reagents
|
|
WO2005026387A1
(en)
|
2003-09-18 |
2005-03-24 |
Nuevolution A/S |
A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
|
|
AU2004292547B9
(en)
*
|
2003-11-20 |
2012-04-26 |
Sanofi Pasteur, Inc. |
Methods for purifying pertussis toxin and peptides useful therefor
|
|
WO2005056764A2
(en)
|
2003-12-05 |
2005-06-23 |
Compound Therapeutics, Inc. |
Inhibitors of type 2 vascular endothelial growth factor receptors
|
|
EP1723255B1
(en)
*
|
2004-02-17 |
2010-12-29 |
Nuevolution A/S |
Method for enrichment involving elimination by mismatch hybridisation
|
|
WO2005090566A2
(en)
*
|
2004-03-22 |
2005-09-29 |
Nuevolution A/S |
Ligational encoding using building block oligonucleotides
|
|
CA2467321A1
(en)
*
|
2004-05-14 |
2005-11-14 |
Paul J. Santerre |
Polymeric coupling agents and pharmaceutically-active polymers made therefrom
|
|
EP1816192B1
(en)
*
|
2004-10-15 |
2012-12-12 |
National Institute of Advanced Industrial Science and Technology |
LINKER FOR CONSTRUCTING mRNA-PUROMYCIN-PROTEIN CONJUGATE
|
|
US10206998B2
(en)
|
2005-01-12 |
2019-02-19 |
Proteonova, Inc. |
Modular targeted therapeutic agents and methods of making same
|
|
EP2261257B1
(en)
|
2005-01-12 |
2018-07-11 |
Proteonova, Inc. |
Method for making targeted therapeutic agents
|
|
EP1951890A4
(en)
|
2005-11-16 |
2009-06-24 |
Ambrx Inc |
PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
|
|
LT2336315T
(lt)
|
2005-12-01 |
2017-11-10 |
Nuevolution A/S |
Fermentiniai kodavimo būdai, skirti efektyviai didelių bibliotekų sintezei
|
|
US7749957B2
(en)
|
2006-04-06 |
2010-07-06 |
E.I. Du Pont De Nemours And Company |
Clay-binding peptides and methods of use
|
|
JP5537946B2
(ja)
|
2006-11-22 |
2014-07-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
|
|
EP2118344B1
(en)
|
2007-02-12 |
2014-07-23 |
Proteonova, Inc. |
GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA
|
|
US7829311B2
(en)
|
2007-07-25 |
2010-11-09 |
E.I. Du Pont De Nemours And Company |
Ketosteroid isomerase inclusion body tag engineered to be acid-resistant by replacing aspartates with glutamate
|
|
US7951559B2
(en)
*
|
2007-07-25 |
2011-05-31 |
E.I. Du Pont De Nemours And Company |
Recombinant peptide production using a cross-linkable solubility tag
|
|
US7678883B2
(en)
*
|
2007-07-25 |
2010-03-16 |
E.I. Du Pont De Nemours And Company |
Solubility tags for the expression and purification of bioactive peptides
|
|
US7794963B2
(en)
|
2007-11-02 |
2010-09-14 |
E.I. Du Pont De Nemours And Company |
Use of tetracysteine tags in fluorescence-activated cell sorting analysis of prokaryotic cells producing peptides or proteins
|
|
KR20210049186A
(ko)
|
2007-11-30 |
2021-05-04 |
애브비 바이오테크놀로지 리미티드 |
단백질 제형 및 이의 제조방법
|
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
|
JP2011517314A
(ja)
|
2008-02-14 |
2011-06-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
Ｅｇｆｒに結合する操作されたタンパク質に基づく標的化された治療薬
|
|
CA2723265C
(en)
*
|
2008-05-02 |
2015-11-24 |
Epicentre Technologies Corporation |
Selective 5' ligation tagging of rna
|
|
US9296810B2
(en)
|
2008-05-02 |
2016-03-29 |
Novartis Ag |
Fibronectin-based binding molecules and uses thereof
|
|
PE20091931A1
(es)
|
2008-05-22 |
2009-12-31 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
WO2010011944A2
(en)
|
2008-07-25 |
2010-01-28 |
Wagner Richard W |
Protein screeing methods
|
|
BRPI0919426A2
(pt)
*
|
2008-09-30 |
2015-12-15 |
Abbott Lab |
métodos melhorado de exposição de rna
|
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
|
|
US20100158846A1
(en)
*
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Hair-binding peptides
|
|
US20100158837A1
(en)
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Iron oxide-binding peptides
|
|
US8287845B2
(en)
*
|
2008-12-18 |
2012-10-16 |
E I Du Pont De Nemours And Company |
Hair-binding peptides
|
|
US20100158822A1
(en)
*
|
2008-12-18 |
2010-06-24 |
E .I. Du Pont De Nemours And Company |
Peptides that bind to silica-coated particles
|
|
BRPI1014677A2
(pt)
*
|
2009-03-30 |
2016-04-12 |
Du Pont |
sistemas baseados em peptídeos para distribuição de agentes cosméticos
|
|
US8481678B2
(en)
|
2009-03-30 |
2013-07-09 |
E I Du Pont De Nemours And Company |
Peptide-based tooth whitening reagents
|
|
JP5733784B2
(ja)
*
|
2009-09-24 |
2015-06-10 |
国立大学法人埼玉大学 |
ｃＤＮＡ／ｍＲＮＡ−タンパク質連結体の効率的合成法
|
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
AU2011214465A1
(en)
|
2010-02-10 |
2012-08-30 |
Novartis Ag |
Methods and compounds for muscle growth
|
|
MX340735B
(es)
*
|
2010-04-09 |
2016-07-22 |
Univ Utrecht Holding Bv |
Proteinas multimericas recombinantes de la influenza.
|
|
CA2832672A1
(en)
|
2010-04-16 |
2011-10-20 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
US9562089B2
(en)
|
2010-05-26 |
2017-02-07 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins having improved stability
|
|
MX345300B
(es)
|
2010-07-30 |
2017-01-24 |
Novartis Ag * |
Moléculas andamio de fibronectina y bibliotecas de las mismas.
|
|
DE102010056289A1
(de)
|
2010-12-24 |
2012-06-28 |
Geneart Ag |
Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken
|
|
US9880160B2
(en)
|
2011-03-15 |
2018-01-30 |
X-Body, Inc. |
Antibody screening methods
|
|
CA2833917C
(en)
|
2011-04-28 |
2020-04-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Identification of polynucleotides associated with a sample.
|
|
US9422550B2
(en)
|
2011-08-01 |
2016-08-23 |
The General Hospital Corporation |
Protein and peptide libraries
|
|
KR20220116585A
(ko)
|
2011-10-11 |
2022-08-23 |
비엘라 바이오, 인크. |
Cd40l 특이적 tn3 유래 스카폴드 및 이의 사용 방법
|
|
WO2013085972A1
(en)
|
2011-12-05 |
2013-06-13 |
X-Body, Inc. |
Pdgf receptor beta binding polypeptides
|
|
JP6020865B2
(ja)
*
|
2013-03-13 |
2016-11-02 |
国立大学法人 東京大学 |
核酸リンカー
|
|
MY191368A
(en)
|
2013-06-28 |
2022-06-20 |
X Body Inc |
Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes
|
|
CN103382579B
(zh)
*
|
2013-07-06 |
2015-10-21 |
中国科学院成都生物研究所 |
一种体外筛选多肽的方法
|
|
US10519436B2
(en)
|
2013-09-23 |
2019-12-31 |
X-Body, Inc. |
Methods and compositions for generation of binding agents against cell surface antigens
|
|
WO2015101516A1
(en)
*
|
2013-12-31 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Enrichment of full-length oligonucleotides via transcription/translation-mediated purification
|
|
EP3102245B1
(en)
|
2014-02-05 |
2021-09-08 |
Molecular Templates, Inc. |
Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
|
|
EP3129401B1
(en)
|
2014-03-20 |
2019-06-12 |
Bristol-Myers Squibb Company |
Serum albumin-binding fibronectin type iii domains
|
|
JP6478392B2
(ja)
*
|
2014-12-26 |
2019-03-06 |
国立研究開発法人産業技術総合研究所 |
核酸リンカー
|
|
CN107428817B
(zh)
|
2015-03-12 |
2022-07-12 |
免疫医疗有限责任公司 |
纯化白蛋白融合蛋白的方法
|
|
ES2781207T3
(es)
|
2015-09-23 |
2020-08-31 |
Bristol Myers Squibb Co |
Dominios de fibronectina de tipo iii de unión a seroalbúmina con velocidad de disociación rápida
|
|
EP4299803A3
(en)
|
2016-05-02 |
2024-03-27 |
Encodia, Inc. |
Macromolecule analysis employing nucleic acid encoding
|
|
CN109790565A
(zh)
*
|
2016-06-15 |
2019-05-21 |
基因捕获公司 |
包含茎-环捕获分子的组合物、方法和装置
|
|
EP3475706B1
(en)
|
2016-06-27 |
2021-08-11 |
Juno Therapeutics, Inc. |
Mhc-e restricted epitopes, binding molecules and related methods and uses
|
|
US20200182884A1
(en)
|
2016-06-27 |
2020-06-11 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
SG11201908817WA
(en)
|
2017-03-21 |
2019-10-30 |
Fujifilm Corp |
Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound
|
|
AU2018358057B2
(en)
|
2017-10-31 |
2023-03-02 |
Encodia, Inc. |
Kits for analysis using nucleic acid encoding and/or label
|
|
US11807623B2
(en)
|
2017-11-30 |
2023-11-07 |
Arrakis Therapeutics, Inc. |
Nucleic acid-binding photoprobes and uses thereof
|
|
WO2019148294A1
(en)
|
2018-02-02 |
2019-08-08 |
Interface Biologics, Inc. |
Dimeric dexamethasone prodrug compositions and uses thereof
|
|
TWI830718B
(zh)
*
|
2018-02-09 |
2024-02-01 |
日商住友化學股份有限公司 |
核酸分子之製造方法
|
|
JP6817493B2
(ja)
*
|
2018-03-30 |
2021-01-20 |
住友化学株式会社 |
一本鎖ｒｎａの製造方法
|
|
WO2019236644A1
(en)
*
|
2018-06-05 |
2019-12-12 |
Arrakis Therapeutics, Inc. |
Encoded libraries and methods of use for screening nucleic acid targets
|
|
US12473326B2
(en)
|
2019-02-01 |
2025-11-18 |
Ripple Therapeutics Corporation |
Crystalline forms of dexamethasone dimers and uses thereof
|
|
US20220347305A1
(en)
|
2019-08-07 |
2022-11-03 |
Ripple Therapeutics Corporation |
Controlled release drug dimers
|
|
WO2021220061A2
(en)
|
2020-05-01 |
2021-11-04 |
Ripple Therapeutics Corporation |
Heterodimer compositions and methods for the treatment of ocular disorders
|