|
CA2377468C
(en)
*
|
1999-07-27 |
2010-04-20 |
Phylos, Inc. |
Peptide acceptor ligation methods
|
|
ATE356231T1
(de)
|
2000-01-11 |
2007-03-15 |
Nanogen Recognomics Gmbh |
Biomoleküle mit multiplen anbindungsabschnitten zur bindung an eine substratoberfläche
|
|
WO2001072998A2
(de)
*
|
2000-03-31 |
2001-10-04 |
Memorec Stoffel Gmbh |
Verfahren zur extraktion von nukleinsäuren
|
|
US7410761B2
(en)
*
|
2000-05-19 |
2008-08-12 |
Proteonova, Inc. |
System for rapid identification and selection of nucleic acids and polypeptides, and method thereof
|
|
US6962781B1
(en)
*
|
2000-05-19 |
2005-11-08 |
Proteonova, Inc. |
In vitro evolution of nucleic acids and encoded polypeptide
|
|
US20040229271A1
(en)
|
2000-05-19 |
2004-11-18 |
Williams Richard B. |
Compositions and methods for the identification and selection of nucleic acids and polypeptides
|
|
WO2003044194A1
(en)
*
|
2001-11-16 |
2003-05-30 |
Proteonova, Inc. |
Selection and evolution of nucleic acids and polypeptides
|
|
US7129229B2
(en)
|
2000-08-11 |
2006-10-31 |
Nanogen Recognomics Gmbh |
Hydrazide building blocks and hydrazide modified biomolecules
|
|
JP4880182B2
(ja)
*
|
2000-08-11 |
2012-02-22 |
ナノジェン・レコグノミクス・ゲーエムベーハー |
ヒドラジド結合部分を有する巨大分子およびそれらの製造用試剤
|
|
JP4963142B2
(ja)
*
|
2000-12-14 |
2012-06-27 |
学校法人慶應義塾 |
遺伝子型と表現型の対応付け分子とその構成要素、および対応付け分子の製造方法と利用方法
|
|
US7727713B2
(en)
*
|
2001-06-20 |
2010-06-01 |
Nuevolution A/S |
Templated molecules and methods for using such molecules
|
|
US20060234231A1
(en)
*
|
2001-06-20 |
2006-10-19 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
|
US6893822B2
(en)
|
2001-07-19 |
2005-05-17 |
Nanogen Recognomics Gmbh |
Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
|
|
EP1419274A4
(en)
*
|
2001-07-31 |
2006-02-08 |
Phylos Inc |
MODULAR CONSTRUCTION OF NUCLEIC ACID PROTEIN FUSION MULTIMERS
|
|
DE10147074A1
(de)
*
|
2001-09-25 |
2003-05-08 |
Beru Ag |
Verfahren zum Betreiben einer aus mehreren Heizelementen bestehenden mehrstufigen elektrischen Heizung
|
|
US7125669B2
(en)
*
|
2001-11-27 |
2006-10-24 |
Compound Therapeutics, Inc. |
Solid-phase immobilization of proteins and peptides
|
|
DE20200926U1
(de)
*
|
2002-01-23 |
2002-04-18 |
Hegenscheidt-MFD GmbH & Co. KG, 41812 Erkelenz |
Festwalzgerät einer Festwalzmaschine für Kurbelwellen
|
|
AU2003218630A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block capable of functional entity transfer to nucleophil
|
|
US20050221318A1
(en)
*
|
2002-03-15 |
2005-10-06 |
Gouliaev Alex H |
Building block forming a c-c bond upon reaction
|
|
US10731151B2
(en)
|
2002-03-15 |
2020-08-04 |
Nuevolution A/S |
Method for synthesising templated molecules
|
|
DE60324778D1
(de)
*
|
2002-03-15 |
2009-01-02 |
Nuevolution As |
Eine verbesserte methode zur synthese von matritzenabhängigen molekülen
|
|
EP1487850A2
(en)
*
|
2002-03-15 |
2004-12-22 |
Nuevolution A/S |
A building block forming a c-c or a c-hetero atom bond upon reaction
|
|
AU2003247266A1
(en)
|
2002-08-01 |
2004-02-23 |
Nuevolution A/S |
Multi-step synthesis of templated molecules
|
|
AU2003256857A1
(en)
*
|
2002-08-08 |
2004-02-25 |
Dharmacon, Inc. |
Short interfering rnas having a hairpin structure containing a non-nucleotide loop
|
|
CN102838654B
(zh)
|
2002-10-30 |
2016-05-18 |
纽韦卢森公司 |
合成双功能复合物的方法
|
|
DE60330406D1
(de)
*
|
2002-12-19 |
2010-01-14 |
Nuevolution As |
Durch quasizufallsstrukturen und funktionen geführte synthesemethode
|
|
US20060269920A1
(en)
*
|
2003-02-21 |
2006-11-30 |
Nuevolution A/S |
Method for obtaining structural information about an encoded molecule
|
|
US20070026397A1
(en)
|
2003-02-21 |
2007-02-01 |
Nuevolution A/S |
Method for producing second-generation library
|
|
DK1608748T3
(da)
*
|
2003-03-20 |
2009-06-29 |
Nuevolution As |
Ligeringskodning af små molekyler
|
|
WO2004110964A2
(en)
*
|
2003-06-16 |
2004-12-23 |
Nuevolution A/S |
Encoded molecules by translation (emt)
|
|
WO2005074417A2
(en)
*
|
2003-09-03 |
2005-08-18 |
Salk Institute For Biological Studies |
Multiple antigen detection assays and reagents
|
|
ATE447626T1
(de)
|
2003-09-18 |
2009-11-15 |
Nuevolution As |
Methode zur gewinnung struktureller informationen kodierter moleküle und zur selektion von verbindungen
|
|
US8299210B2
(en)
*
|
2003-11-20 |
2012-10-30 |
Sanofi Pasteur |
Methods for purifying pertussis toxin and peptides useful therefor
|
|
BRPI0417302A
(pt)
|
2003-12-05 |
2007-03-06 |
Compound Therapeutics Inc |
inibidores de receptores de fator de crescimento endotelial vascular do tipo 2
|
|
AU2004314705A1
(en)
*
|
2003-12-12 |
2005-08-11 |
Proteonova, Inc. |
System and methods for nucleic acid and polypeptide selection
|
|
US20090239211A1
(en)
*
|
2004-02-17 |
2009-09-24 |
Nuevolution A/S |
Method For Enrichment Involving Elimination By Mismatch Hybridisation
|
|
WO2005090566A2
(en)
*
|
2004-03-22 |
2005-09-29 |
Nuevolution A/S |
Ligational encoding using building block oligonucleotides
|
|
CA2467321A1
(en)
*
|
2004-05-14 |
2005-11-14 |
Paul J. Santerre |
Polymeric coupling agents and pharmaceutically-active polymers made therefrom
|
|
JP4318721B2
(ja)
*
|
2004-10-15 |
2009-08-26 |
独立行政法人科学技術振興機構 |
ｍＲＮＡ−ピューロマイシン−タンパク質連結体作製用リンカー
|
|
EP1846432A4
(en)
|
2005-01-12 |
2008-11-19 |
Proteonova Inc |
METHOD FOR PRODUCING TARGETED THERAPEUTIC AGENTS
|
|
US10206998B2
(en)
|
2005-01-12 |
2019-02-19 |
Proteonova, Inc. |
Modular targeted therapeutic agents and methods of making same
|
|
EP1951890A4
(en)
|
2005-11-16 |
2009-06-24 |
Ambrx Inc |
PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
|
|
LT3018206T
(lt)
|
2005-12-01 |
2021-12-10 |
Nuevolution A/S |
Fermentiniai kodavimo būdai, skirti didelių bibliotekų efektyviai sintezei
|
|
US7749957B2
(en)
|
2006-04-06 |
2010-07-06 |
E.I. Du Pont De Nemours And Company |
Clay-binding peptides and methods of use
|
|
AU2007325838B2
(en)
|
2006-11-22 |
2013-09-19 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR
|
|
JP2010517583A
(ja)
|
2007-02-12 |
2010-05-27 |
プロテオノヴァ、 インコーポレイテッド |
ｍＲＮＡに連結された可溶性ランダムポリペプチドのライブラリーの生成
|
|
US7829311B2
(en)
|
2007-07-25 |
2010-11-09 |
E.I. Du Pont De Nemours And Company |
Ketosteroid isomerase inclusion body tag engineered to be acid-resistant by replacing aspartates with glutamate
|
|
US7678883B2
(en)
*
|
2007-07-25 |
2010-03-16 |
E.I. Du Pont De Nemours And Company |
Solubility tags for the expression and purification of bioactive peptides
|
|
US7951559B2
(en)
*
|
2007-07-25 |
2011-05-31 |
E.I. Du Pont De Nemours And Company |
Recombinant peptide production using a cross-linkable solubility tag
|
|
WO2009135212A2
(en)
*
|
2008-05-02 |
2009-11-05 |
Epicentre Technologies Corporation |
Selective 5' ligation tagging of rna
|
|
US7794963B2
(en)
|
2007-11-02 |
2010-09-14 |
E.I. Du Pont De Nemours And Company |
Use of tetracysteine tags in fluorescence-activated cell sorting analysis of prokaryotic cells producing peptides or proteins
|
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
|
US8420081B2
(en)
|
2007-11-30 |
2013-04-16 |
Abbvie, Inc. |
Antibody formulations and methods of making same
|
|
EP2247615B1
(en)
|
2008-02-14 |
2014-07-30 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins that bind egfr
|
|
CN102076713B
(zh)
|
2008-05-02 |
2015-03-25 |
诺华股份有限公司 |
改进的基于纤连蛋白的结合分子及其用途
|
|
AR071874A1
(es)
|
2008-05-22 |
2010-07-21 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
KR20110036638A
(ko)
|
2008-07-25 |
2011-04-07 |
리차드 더블유. 와그너 |
단백질 스크리닝 방법
|
|
MX2011003381A
(es)
*
|
2008-09-30 |
2011-04-21 |
Abbott Lab |
Metodo mejorado para despliegue de arn.
|
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
|
|
US20100158837A1
(en)
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Iron oxide-binding peptides
|
|
US8287845B2
(en)
*
|
2008-12-18 |
2012-10-16 |
E I Du Pont De Nemours And Company |
Hair-binding peptides
|
|
US20100158822A1
(en)
*
|
2008-12-18 |
2010-06-24 |
E .I. Du Pont De Nemours And Company |
Peptides that bind to silica-coated particles
|
|
US20100158846A1
(en)
*
|
2008-12-18 |
2010-06-24 |
E. I. Du Pont De Nemours And Company |
Hair-binding peptides
|
|
CN102596155A
(zh)
*
|
2009-03-30 |
2012-07-18 |
庄臣消费者有限公司 |
用于递送美容试剂的基于肽的系统
|
|
WO2010114638A1
(en)
|
2009-03-30 |
2010-10-07 |
E. I. Du Pont De Nemours And Company |
Peptide-based tooth whitening reagents
|
|
JP5733784B2
(ja)
*
|
2009-09-24 |
2015-06-10 |
国立大学法人埼玉大学 |
ｃＤＮＡ／ｍＲＮＡ−タンパク質連結体の効率的合成法
|
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
MX2012009318A
(es)
|
2010-02-10 |
2012-09-07 |
Novartis Ag |
Metodos y compuestos para el crecimiento muscular.
|
|
US20130034578A1
(en)
*
|
2010-04-09 |
2013-02-07 |
Petrus Josephus Marie Rottier |
Recombinant multimeric influenza proteins
|
|
SI2558577T1
(sl)
|
2010-04-16 |
2019-05-31 |
Nuevolution A/S |
Bifunkcionalni kompleksi in metode za pripravo in uporabo takšnih kompleksov
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
EP3091028A1
(en)
|
2010-05-26 |
2016-11-09 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins having improved stability
|
|
AU2011283646B2
(en)
|
2010-07-30 |
2015-07-09 |
Novartis Ag |
Fibronectin cradle molecules and libraries thereof
|
|
DE102010056289A1
(de)
|
2010-12-24 |
2012-06-28 |
Geneart Ag |
Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken
|
|
EP3798236B1
(en)
|
2011-03-15 |
2022-08-10 |
X-Body, Inc. |
Antibody screening methods
|
|
SG10201900183VA
(en)
|
2011-04-28 |
2019-05-30 |
Univ Leland Stanford Junior |
Identification of polynucleotides associated with a sample
|
|
EP2742153B1
(en)
|
2011-08-01 |
2018-09-05 |
The General Hospital Corporation |
Protein and peptide libraries
|
|
KR102434073B1
(ko)
|
2011-10-11 |
2022-08-18 |
비엘라 바이오, 인크. |
Cd40l 특이적 tn3 유래 스카폴드 및 이의 사용 방법
|
|
CN107353342B
(zh)
|
2011-12-05 |
2021-08-10 |
X 博迪生物科学公司 |
PDGF受体β结合多肽
|
|
EP2975121A4
(en)
*
|
2013-03-13 |
2016-07-20 |
Univ Tokyo |
NUCLEIC LEFT
|
|
US10370651B2
(en)
|
2013-06-28 |
2019-08-06 |
X-Body, Inc. |
Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes
|
|
CN103382579B
(zh)
*
|
2013-07-06 |
2015-10-21 |
中国科学院成都生物研究所 |
一种体外筛选多肽的方法
|
|
AU2014321251B2
(en)
|
2013-09-23 |
2020-04-16 |
X-Body, Inc. |
Methods and compositions for generation of binding agents against cell surface antigens
|
|
WO2015101516A1
(en)
*
|
2013-12-31 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Enrichment of full-length oligonucleotides via transcription/translation-mediated purification
|
|
JP6814634B2
(ja)
|
2014-02-05 |
2021-01-20 |
モレキュラー テンプレーツ, インク.Molecular Templates, Inc. |
リボ毒性の一時的な減少に基づき、細胞毒性組換えポリペプチドをスクリーニングし、選択し、同定する方法
|
|
AU2015231170B2
(en)
|
2014-03-20 |
2019-10-03 |
Bristol-Myers Squibb Company |
Serum albumin-binding fibronectin type III domains
|
|
JP6478392B2
(ja)
*
|
2014-12-26 |
2019-03-06 |
国立研究開発法人産業技術総合研究所 |
核酸リンカー
|
|
JP6862348B2
(ja)
|
2015-03-12 |
2021-04-21 |
メディミューン，エルエルシー |
アルブミン融合タンパク質を精製する方法
|
|
US10766946B2
(en)
|
2015-09-23 |
2020-09-08 |
Bristol-Myers Squibb Company |
Fast-off rate serum albumin binding fibronectin type III domains
|
|
KR102516168B1
(ko)
|
2016-05-02 |
2023-03-30 |
엔코디아, 인코포레이티드 |
암호화 핵산을 사용한 거대분자 분석
|
|
WO2017218858A1
(en)
*
|
2016-06-15 |
2017-12-21 |
Genecapture, Inc. |
Compositions, methods and devices comprising stem-loop captor molecules
|
|
US20200182884A1
(en)
|
2016-06-27 |
2020-06-11 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
JP7054397B2
(ja)
|
2016-06-27 |
2022-04-13 |
ジュノー セラピューティクス インコーポレイテッド |
Ｍｈｃ－ｅ拘束性エピトープ、結合分子ならびに関連する方法および使用
|
|
SG11201908817WA
(en)
|
2017-03-21 |
2019-10-30 |
Fujifilm Corp |
Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound
|
|
MX2020004559A
(es)
*
|
2017-10-31 |
2020-10-05 |
Encodia Inc |
Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
|
|
MX2020003695A
(es)
|
2017-11-30 |
2020-08-03 |
Arrakis Therapeutics Inc |
Fotosondas de union a acido nucleico y usos de las mismas.
|
|
EP3740494A4
(en)
|
2018-02-02 |
2021-11-03 |
Ripple Therapeutics Corporation |
GLASS FORMULATIONS WITH STEROID DIMERS AND USES THEREOF
|
|
TWI830718B
(zh)
*
|
2018-02-09 |
2024-02-01 |
日商住友化學股份有限公司 |
核酸分子之製造方法
|
|
US20210115485A1
(en)
*
|
2018-03-30 |
2021-04-22 |
Sumitomo Chemical Company, Limited |
Method for producing single-strand rna
|
|
WO2019236644A1
(en)
*
|
2018-06-05 |
2019-12-12 |
Arrakis Therapeutics, Inc. |
Encoded libraries and methods of use for screening nucleic acid targets
|
|
WO2020154815A1
(en)
|
2019-02-01 |
2020-08-06 |
Ripple Therapeutics Corporation |
Crystalline forms of dexamethasone dimers and uses thereof
|
|
US12509469B2
(en)
|
2019-08-07 |
2025-12-30 |
Ripple Therapeutics Corporation |
Compositions and methods for the treatment of pain and dependence disorders
|
|
CA3176134A1
(en)
|
2020-05-01 |
2021-11-04 |
Ripple Therapeutics Corporation |
Heterodimer compositions and methods for the treatment of ocular disorders
|