|
US3314970A
(en)
|
|
1967-04-18 |
|
Pykrolidino ketones |
|
US2282907A
(en)
|
1941-05-01 |
1942-05-12 |
Us Rubber Co |
Parasiticide
|
|
US2649444A
(en)
|
1948-10-19 |
1953-08-18 |
Burroughs Wellcome Co |
Process for the preparation of amino ketones
|
|
US2778853A
(en)
|
1952-09-10 |
1957-01-22 |
Merck & Co Inc |
Deamination process
|
|
US2771391A
(en)
|
1953-08-20 |
1956-11-20 |
Allied Lab Inc |
Physiologically active p-alkoxy-beta-piperidinopropiophenones causing cns depressantand anesthetic effects in animals
|
|
US2997479A
(en)
|
1955-07-01 |
1961-08-22 |
Endo Lab |
1, 1-diphenyl-1-hydroxy-4-(pyrrolidyl)-butanone-2
|
|
BE561320A
(nl)
*
|
1956-10-04 |
1960-05-20 |
Lab Pharmaceutica Nv |
Werkwijze voor de bereiding van nieuwe 4-carbalkoxy-4-fenyl piperidine derivaten.
|
|
US3080372A
(en)
|
1960-03-25 |
1963-03-05 |
Res Lab Dr C Janssen |
1-aroylalkyl-4-arylpiperidine derivatives
|
|
CH402859A
(de)
|
1960-05-24 |
1965-11-30 |
Wander Ag Dr A |
Verfahren zur Herstellung von a-Pyrrolidino-valerophenonen
|
|
US3151124A
(en)
|
1961-11-20 |
1964-09-29 |
Ciba Geigy Corp |
Alpha oxy-beta alkyl-gamma tertiary amino-alpha phenyl propanes
|
|
US3252996A
(en)
|
1962-10-02 |
1966-05-24 |
Ciba Geigy Corp |
Alpha-pyrrolidinomethyl valero and caprophenones
|
|
BE633437A
(https=)
|
1962-06-11 |
|
|
|
|
US3203962A
(en)
|
1962-10-11 |
1965-08-31 |
Ciba Geigy Corp |
Alpha-phenyl-beta pyrrolidino-propiophenones
|
|
US3310566A
(en)
|
1963-11-18 |
1967-03-21 |
American Home Prod |
Substituted 4-piperidino-butyrophenone oximes
|
|
US3284453A
(en)
*
|
1964-09-29 |
1966-11-08 |
American Cyanamid Co |
4-(2-aroylethyl)-1-piperazinecarboxylic acid esters
|
|
US3340300A
(en)
|
1964-10-05 |
1967-09-05 |
American Cyanamid Co |
Trimethoxy benzoylacetaldehyde oximes
|
|
NL143925C
(https=)
|
1965-03-09 |
|
|
|
|
US3816433A
(en)
|
1965-03-24 |
1974-06-11 |
Ferrosan Ab |
4-fluoro-ypsilon-(4-methylpiperidino)-butyrophenone and its pharmaceutically acceptable salts
|
|
GB1079520A
(en)
*
|
1965-07-19 |
1967-08-16 |
Roche Products Ltd |
Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof
|
|
US3317538A
(en)
|
1965-10-22 |
1967-05-02 |
American Home Prod |
4, 4'-diamino-butyrophenones
|
|
US3417087A
(en)
|
1965-12-27 |
1968-12-17 |
Research Corp |
3(aminopropionyl)benzothiophenes
|
|
US3364120A
(en)
*
|
1966-01-24 |
1968-01-16 |
Babcock & Wilcox Co |
Nuclear control rod actuator
|
|
US3637704A
(en)
|
1967-10-18 |
1972-01-25 |
Dainippon Pharmaceutical Co |
1gamma-(p-fluorobenzoyl)propyl-4-phenylalkyl piperazine
|
|
GB1186495A
(en)
|
1968-02-20 |
1970-04-02 |
Delalande Sa |
0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation
|
|
GB1196721A
(en)
|
1968-02-23 |
1970-07-01 |
Ici Ltd |
Piperazine Derivatives
|
|
CH502336A
(de)
|
1968-04-29 |
1971-01-31 |
Ciba Geigy Ag |
Verfahren zur Herstellung von neuen Estern substituierter Phenylessigsäuren
|
|
US3465080A
(en)
|
1968-10-07 |
1969-09-02 |
American Cyanamid Co |
Therapeutic compositions containing morpholinoalkylene - indoles and methods of administering such in the treatment of depression
|
|
FR2035749A1
(https=)
*
|
1969-02-06 |
1970-12-24 |
Bellon Labor Sa Roger |
|
|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
GB1262965A
(en)
|
1969-03-21 |
1972-02-09 |
Ferrosan As |
Butyrophenones
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3651085A
(en)
|
1969-04-14 |
1972-03-21 |
Robins Co Inc A H |
1-(omega-benzoylalkyl)-3-substituted pyrrolidines
|
|
US3703527A
(en)
|
1969-06-04 |
1972-11-21 |
Hoffmann La Roche |
Preparation of mannich-bases
|
|
US3907812A
(en)
|
1969-07-16 |
1975-09-23 |
Sumitomo Chemical Co |
Butyrophenone derivatives
|
|
US3936468A
(en)
|
1969-10-27 |
1976-02-03 |
Sumitomo Chemical Company, Ltd. |
Phenylbutanol derivatives
|
|
US3799932A
(en)
|
1970-03-20 |
1974-03-26 |
Sumitomo Chemical Co |
Gamma-piperidinobutyrophenones
|
|
US3651067A
(en)
|
1970-04-15 |
1972-03-21 |
Usv Pharma Corp |
Styrene ethers of amino alcohols
|
|
DE2021470A1
(de)
|
1970-05-02 |
1971-11-25 |
Cassella Farbwerke Mainkur Ag |
Piperazinderivate
|
|
FR2092133B1
(https=)
|
1970-05-06 |
1974-03-22 |
Orsymonde |
|
|
US4029801A
(en)
|
1970-09-03 |
1977-06-14 |
John Wyeth & Brother Limited |
Pharmaceutical compositions and methods of treating hypertension
|
|
US4148796A
(en)
|
1971-03-15 |
1979-04-10 |
Sumitomo Chemical Company, Limited |
γ-Piperidinobutyrophenones
|
|
US3794677A
(en)
|
1971-07-01 |
1974-02-26 |
American Home Prod |
Di(lower)alkylamino-and heteroamino-(lower)alkyl-alpha,alpha,alpha-trifluoro-m-toluic acid esters and derivatives
|
|
US3969356A
(en)
|
1971-09-13 |
1976-07-13 |
Kali-Chemie Aktiengesellschaft |
N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphenyl)-ethyl]-p
|
|
US3850935A
(en)
|
1971-10-16 |
1974-11-26 |
Sumitomo Chemical Co |
Process for producing piperidine derivatives by degrading quaternary piperidinium salts
|
|
JPS4948957B2
(https=)
|
1971-10-26 |
1974-12-24 |
|
|
|
US3806526A
(en)
|
1972-01-28 |
1974-04-23 |
Richardson Merrell Inc |
1-aroylalkyl-4-diphenylmethyl piperidines
|
|
BE795671A
(fr)
*
|
1972-02-21 |
1973-08-20 |
Ugine Kuhlmann |
Nouveaux medicaments antiuriques
|
|
US3951978A
(en)
|
1972-04-22 |
1976-04-20 |
Istituto Luso Farmaco D'italia S.R.L. |
1,3-Disubstituted 3-aroylpropanes and process for the preparation thereof
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3922266A
(en)
|
1972-06-28 |
1975-11-25 |
Sumitomo Chemical Co |
Aryl ketones and production thereof
|
|
US3900478A
(en)
|
1973-01-29 |
1975-08-19 |
Squibb & Sons Inc |
2-methyl-2-piperidino-3'-(trifluoromethyl) propiophenone
|
|
CH591464A5
(https=)
|
1973-03-12 |
1977-09-15 |
Kali Chemie Ag |
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US3873539A
(en)
|
1973-10-03 |
1975-03-25 |
Sandoz Ag |
Substituted-4-aminoacetyl alkanoylphenones
|
|
US3992546A
(en)
|
1973-10-18 |
1976-11-16 |
Ciba-Geigy Corporation |
4-Piperidinobutyrophenones as neuroleptics
|
|
US4054570A
(en)
|
1973-10-18 |
1977-10-18 |
Ciba-Geigy Corporation |
4-Piperidinobutyrophenones
|
|
US3944064A
(en)
|
1973-10-26 |
1976-03-16 |
Alza Corporation |
Self-monitored device for releasing agent at functional rate
|
|
US3995047A
(en)
|
1973-12-14 |
1976-11-30 |
Eisai Co., Ltd. |
Propiophenone derivatives in the treatment of pathological muscular conditions
|
|
US4181803A
(en)
|
1973-12-14 |
1980-01-01 |
Eisai Co., Ltd. |
Propiophenone derivatives and preparation thereof
|
|
US3912755A
(en)
|
1974-01-30 |
1975-10-14 |
Lilly Co Eli |
Preparation of pharmaceutical intermediates
|
|
US3931197A
(en)
|
1974-02-08 |
1976-01-06 |
Richardson-Merrell Inc. |
Substituted piperidine derivatives
|
|
US4069331A
(en)
|
1974-05-16 |
1978-01-17 |
Boehringer Ingelheim Gmbh |
N-(p-fluorobenzoyl-n-propyl)-4-piperidylamides and salts thereof
|
|
IL48319A0
(en)
|
1974-10-26 |
1975-12-31 |
Merck Patent Gmbh |
Araliphatic nitrogen compounds and a process for their preparation
|
|
US4028366A
(en)
|
1975-01-20 |
1977-06-07 |
Sterling Drug Inc. |
2-Naphthyl-lower-alkanoylamines
|
|
US4169892A
(en)
*
|
1975-04-03 |
1979-10-02 |
Innothera |
1-(benzothien-2'-yl)-3-morpholino propanones and therapeutic compositions containing same
|
|
GB1498884A
(en)
|
1975-04-15 |
1978-01-25 |
Wyeth John & Brother Ltd |
Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives
|
|
IL49971A0
(en)
|
1975-07-08 |
1976-09-30 |
Troponwerke Dinklage & Co |
New 2-benzoypranone derivatives,their preparation and pharmaceutical compositions containing them
|
|
FI60559C
(fi)
|
1975-07-17 |
1982-02-10 |
Sumitomo Chemical Co |
Foerfarande foer framstaellning av ny-(tertiaer amino)-orto-aminobutyrofenonfoereningar
|
|
FR2325379A1
(fr)
|
1975-09-29 |
1977-04-22 |
Cerm Cent Europ Rech Mauvernay |
Nouveaux derives de 2-(2-hydroxyethyl)tetrahydro-1,4 oxazines substituees et leur application comme medicaments antispasmodique
|
|
DE2557341A1
(de)
|
1975-12-19 |
1977-06-30 |
Hoechst Ag |
Basisch substituierte indolderivate und verfahren zu ihrer herstellung
|
|
US4333941A
(en)
|
1975-12-22 |
1982-06-08 |
The Dow Chemical Company |
Inhibition of enveloped viruses with phenyl ketones
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
FR2361883A2
(fr)
|
1976-04-09 |
1978-03-17 |
Fabre Sa Pierre |
Amides de la pyrrolidino ethyl amine utilisables en therapeutique pulmonaire
|
|
DE2718405A1
(de)
|
1977-04-26 |
1978-11-02 |
Boehringer Sohn Ingelheim |
Neue n- eckige klammer auf 1-(3-benzoylpropyl)-4-piperidyl eckige klammer zu -sulfonsaeureamide und verfahren zu deren herstellung
|
|
JPS54125630A
(en)
|
1978-02-22 |
1979-09-29 |
Nippon Zoki Pharmaceutical Co |
Novel propanone derivative*its manufacture and medical composition containing it as active component
|
|
DE2933636A1
(de)
|
1978-08-30 |
1980-03-20 |
Sandoz Ag |
Neue n-phenylindolinderivate, ihre herstellung und pharmazeutische praeparate, welche diese verbindungen enthalten
|
|
FR2443246A1
(fr)
|
1978-12-05 |
1980-07-04 |
Pharmindustrie |
Nouveaux medicaments a base de derives de la phenyl-1 (piperidyl-4)-3 propanone-1
|
|
US4293561A
(en)
*
|
1979-03-09 |
1981-10-06 |
Syntex (U.S.A.) Inc. |
1-(Naphthyl-n-propyl)imidazole derivatives
|
|
US4283404A
(en)
|
1979-09-04 |
1981-08-11 |
Richardson-Merrell Inc. |
Aroylethenylpiperidinobutyrophenone antipsychotic agents
|
|
DE2939292A1
(de)
|
1979-09-28 |
1981-04-09 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
N-phenoxyalkylpiperidin-derivate, verfahrenn zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
|
|
DE3041199A1
(de)
*
|
1979-11-14 |
1981-05-21 |
Sandoz-Patent-GmbH, 7850 Lörrach |
Neue stilbenverbindungen, deren herstellung und verwendung
|
|
FR2473518A1
(fr)
|
1980-01-16 |
1981-07-17 |
Unicler |
Derives du phenyl-1 morpholino-4 butene-1 ol-3, leur preparation et leur application en therapeutique
|
|
DE3019496A1
(de)
|
1980-05-22 |
1981-11-26 |
Bayer Ag, 5090 Leverkusen |
Aminopropanol-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
|
|
DE3019497A1
(de)
|
1980-05-22 |
1981-11-26 |
Bayer Ag, 5090 Leverkusen |
Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
|
|
US4400380A
(en)
|
1980-07-02 |
1983-08-23 |
Merrell Dow Pharmaceuticals Inc. |
Antiviral 1-aryl-5-amino-1-penten-3-ones
|
|
US4397850A
(en)
|
1981-10-07 |
1983-08-09 |
Sandoz, Inc. |
Isoxazolyl indolamines
|
|
JPS5944371A
(ja)
|
1982-09-07 |
1984-03-12 |
Dainippon Pharmaceut Co Ltd |
１―フエニル―２―メチル―３―（１―ピロリジニル）―１―プロパノン誘導体
|
|
FR2534912B1
(fr)
|
1982-10-26 |
1985-06-28 |
Lafon Labor |
Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation
|
|
US4559371A
(en)
|
1983-02-18 |
1985-12-17 |
Ciba Geigy Corporation |
Photocurable colored compositions employing alpha-amino phenone initiator
|
|
US4515793A
(en)
*
|
1983-07-27 |
1985-05-07 |
Edna Mcconnell Clark Foundation |
Phenylpiperazines which are useful in the treatment of schistosomiasis
|
|
DE3471486D1
(de)
|
1983-08-15 |
1988-06-30 |
Ciba Geigy Ag |
Photocurable compositions
|
|
HU33131A
(https=)
|
1984-01-26 |
1984-10-29 |
|
|
|
FR2560873B1
(fr)
*
|
1984-03-09 |
1986-09-26 |
Rhone Poulenc Sante |
Medicaments a base de derives de la piperidine, nouveaux derives de la piperidine et leurs procedes de preparation
|
|
DE3413897A1
(de)
|
1984-04-13 |
1985-10-17 |
Bayer Ag, 5090 Leverkusen |
(beta)-naphthylalkylamine
|
|
US4544663A
(en)
|
1984-05-07 |
1985-10-01 |
Sandoz, Inc. |
Indolamine derivatives as anti-fertility agents
|
|
DE3436450A1
(de)
|
1984-10-05 |
1986-04-10 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur herstellung von p-aminoethylketonen
|
|
US5057535A
(en)
|
1985-04-11 |
1991-10-15 |
Nippon Kayaku Kabushiki Kaisha |
Derivatives of an aminoketone
|
|
FR2584715B1
(fr)
|
1985-07-10 |
1987-10-09 |
Lafon Labor |
Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique
|
|
EP0219756B1
(de)
|
1985-10-09 |
1994-01-05 |
Shell Internationale Researchmaatschappij B.V. |
Neue Acrylsäureamide
|
|
DE3602016A1
(de)
|
1985-12-05 |
1987-06-11 |
Bayer Ag |
Pyri(mi)dyl-oxy- und thio-benzoesaeure-derivate
|
|
FR2597864B1
(fr)
|
1986-04-28 |
1990-11-16 |
Lafon Labor |
Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique
|
|
KR910006138B1
(ko)
*
|
1986-09-30 |
1991-08-16 |
에자이 가부시끼가이샤 |
환상아민 유도체
|
|
US4766118A
(en)
*
|
1986-12-22 |
1988-08-23 |
Ortho Pharmaceutical Corporation |
6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use
|
|
JPH0637389B2
(ja)
|
1986-12-26 |
1994-05-18 |
北陸製薬株式会社 |
頻尿治療剤
|
|
KR960004827B1
(ko)
|
1987-01-20 |
1996-04-16 |
다이닛뽄 세이야꾸 가부시끼가이샤 |
헤테로아릴카르복시아미드 유도체, 그의 제조방법 및 그것을 함유하는 의약조성물
|
|
US4840950A
(en)
|
1987-02-11 |
1989-06-20 |
Sterling Drug Inc. |
4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles
|
|
US4874761A
(en)
|
1987-02-11 |
1989-10-17 |
Sterling Drug Inc. |
4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles
|
|
EP0284561B1
(de)
|
1987-03-26 |
1993-05-12 |
Ciba-Geigy Ag |
Neue alpha-Aminoacetophenone als Photoinitiatoren
|
|
US4870083A
(en)
|
1987-11-24 |
1989-09-26 |
Merrell Dow Pharmaceuticals Inc. |
1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants
|
|
US5196439A
(en)
|
1987-11-27 |
1993-03-23 |
Eisai Co., Ltd. |
Piperidine compounds useful to treat cerebrovascular diseases
|
|
US4791045A
(en)
*
|
1988-01-25 |
1988-12-13 |
Minnesota Mining And Manufacturing Company |
Photosensitizers and polymerizable compositions with mannich bases and iodonium salts
|
|
IT1231260B
(it)
|
1988-11-16 |
1991-11-28 |
Sergio Bertini Curri |
Farmaco e metodo per aumentare volume e velocita' del flusso microcircolatorio capillare a livello cutaneo
|
|
JPH0660141B2
(ja)
|
1989-09-12 |
1994-08-10 |
三井東圧化学株式会社 |
ジヒドロカフェイン酸誘導体およびそれを有効成分として含有する治療剤
|
|
US5182284A
(en)
|
1990-01-26 |
1993-01-26 |
Taiho Pharmaceutical Co., Ltd. |
Piperazine compounds, processes for preparation thereof and medical uses thereof
|
|
US5013837A
(en)
|
1990-03-08 |
1991-05-07 |
Sterling Drug Inc. |
3-Arylcarbonyl-1H-indole-containing compounds
|
|
US5276035A
(en)
|
1990-07-26 |
1994-01-04 |
Novo Nordisk A/S |
1,4-disubstituted piperazines
|
|
US5750542A
(en)
|
1993-09-28 |
1998-05-12 |
Pfizer |
Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
|
|
FR2680366B1
(fr)
|
1991-08-13 |
1995-01-20 |
Adir |
Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
JP3157882B2
(ja)
|
1991-11-15 |
2001-04-16 |
帝国臓器製薬株式会社 |
新規なベンゾチオフエン誘導体
|
|
US5674878A
(en)
|
1992-06-22 |
1997-10-07 |
Boehringer Ingelheim Kg |
Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparations
|
|
US5324483B1
(en)
*
|
1992-10-08 |
1996-09-24 |
Warner Lambert Co |
Apparatus for multiple simultaneous synthesis
|
|
GB9301660D0
(en)
|
1993-01-28 |
1993-03-17 |
Smithkline Beecham Plc |
Pharmaceuticals
|
|
US6127379A
(en)
|
1993-02-01 |
2000-10-03 |
Smithkline Beecham P.L.C. |
Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
|
|
ATE146775T1
(de)
|
1993-02-23 |
1997-01-15 |
Hoechst Ag |
Substituierte benzolsulfonylharnstoffe und - thioharnstoffe- verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika
|
|
ATE219766T1
(de)
|
1993-04-07 |
2002-07-15 |
Otsuka Pharma Co Ltd |
N-acylierte 4-aminopiperidin derivate als aktive bestandteile von peripher gefässerweiternden wikstoffen
|
|
US5350748A
(en)
|
1993-08-18 |
1994-09-27 |
Warner-Lambert Company |
3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion
|
|
GB9324018D0
(en)
|
1993-11-23 |
1994-01-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
FR2713637B1
(fr)
|
1993-12-15 |
1996-01-05 |
Cird Galderma |
Nouveaux composés bi-aromatiques dérivés d'amide, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
|
|
DK139593D0
(da)
|
1993-12-16 |
1993-12-16 |
Lundbeck & Co As H |
Compounds
|
|
CA2178088A1
(en)
|
1993-12-21 |
1995-06-29 |
Walter Losel |
Anellated dihydropyridines and their use in the production of pharmaceutical preparations
|
|
GB9408185D0
(en)
|
1994-04-25 |
1994-06-15 |
Fujisawa Pharmaceutical Co |
New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
|
|
US5552402A
(en)
|
1994-05-19 |
1996-09-03 |
Merck, Sharp & Dohme Ltd. |
Five-membered heteroaromatic compounds as 5-HT receptor agonists
|
|
US5618819A
(en)
|
1994-07-07 |
1997-04-08 |
Adir Et Compagnie |
1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds
|
|
US5705501A
(en)
*
|
1994-11-17 |
1998-01-06 |
Molecular Geriatrics Corporation |
Certain substituted 1-aryl-3-morpholinopropanones to treat Alzheimer's Disease
|
|
US6214994B1
(en)
|
1997-04-21 |
2001-04-10 |
Molecular Geriatrics Corporation |
Certain substituted 1-aryl-3-piperazin-1′-yl propanones
|
|
GB9423460D0
(en)
|
1994-11-21 |
1995-01-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ATE237589T1
(de)
|
1995-06-07 |
2003-05-15 |
Pfizer |
Catecholdiether-derivate verwendbar als pharmazeutische mittel
|
|
GB9511694D0
(en)
|
1995-06-09 |
1995-08-02 |
Fujisawa Pharmaceutical Co |
Benzamide derivatives
|
|
PT891332E
(pt)
|
1996-03-29 |
2004-07-30 |
Pfizer |
Derivados de 6-fenilpiridil-2-amina
|
|
SK285353B6
(sk)
|
1996-04-12 |
2006-11-03 |
G. D. Searle & Co. |
Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia
|
|
CN1219171A
(zh)
|
1996-05-20 |
1999-06-09 |
达尔文发现有限公司 |
苯并呋喃甲酰胺及其治疗用途
|
|
US6555690B2
(en)
|
1996-06-21 |
2003-04-29 |
Allergan, Inc. |
Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
|
|
JP2000516611A
(ja)
|
1996-08-14 |
2000-12-12 |
ワーナー―ランバート・コンパニー |
Ｍｃｐ―１アンタゴニストとしての２―フェニルベンズイミダゾール誘導体
|
|
TW452575B
(en)
|
1996-12-06 |
2001-09-01 |
Ciba Sc Holding Ag |
New Α-aminoacetophenone photoinitiators and photopolymerizable compositions comprising these photoinitiators
|
|
US5994398A
(en)
|
1996-12-11 |
1999-11-30 |
Elan Pharmaceuticals, Inc. |
Arylsulfonamides as phospholipase A2 inhibitors
|
|
US6281227B1
(en)
|
1996-12-13 |
2001-08-28 |
Aventis Pharma Deutschland Gmbh |
Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
|
|
FR2761358B1
(fr)
|
1997-03-27 |
1999-05-07 |
Adir |
Nouveaux composes de n-aryl piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6207665B1
(en)
|
1997-06-12 |
2001-03-27 |
Schering Aktiengesellschaft |
Piperazine derivatives and their use as anti-inflammatory agents
|
|
US20010049379A1
(en)
|
1997-08-27 |
2001-12-06 |
Lowe John Adams |
2-aminopyridines containing fused ring substituents
|
|
HN1998000125A
(es)
|
1997-08-28 |
1999-02-09 |
Pfizer Prod Inc |
2-aminopiridinas con sustituyentes alcoxi ramificados
|
|
US5972986A
(en)
|
1997-10-14 |
1999-10-26 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
|
|
US6140349A
(en)
|
1998-02-02 |
2000-10-31 |
Merck & Co., Inc. |
Cyclic amine modulators of chemokine receptor activity
|
|
US6528529B1
(en)
|
1998-03-31 |
2003-03-04 |
Acadia Pharmaceuticals Inc. |
Compounds with activity on muscarinic receptors
|
|
US6462036B1
(en)
*
|
1998-11-06 |
2002-10-08 |
Basf Aktiengesellschaft |
Tricyclic pyrazole derivatives
|
|
AR022338A1
(es)
|
1999-02-04 |
2002-09-04 |
Hokuriku Pharmaceutical |
Un compuesto de benzamida, medicamento que lo contiene, y uso para la manufactura de un medicamento para el tratamiento o prevencion de una enfermedad digestiva o para mejorar la movilidad del tracto gastrointestinal.
|
|
AUPP873799A0
(en)
|
1999-02-17 |
1999-03-11 |
Fujisawa Pharmaceutical Co., Ltd. |
Pyridine compounds
|
|
ES2295009T3
(es)
|
1999-03-25 |
2008-04-16 |
Mitsubishi Tanabe Pharma Corporation |
Inhibidores de rho quinasa para la profilaxis y el tratamiento de neumonia intersticial y fibrosis pulmonar.
|
|
US7361666B2
(en)
|
1999-05-25 |
2008-04-22 |
Sepracor, Inc. |
Heterocyclic analgesic compounds and methods of use thereof
|
|
US6677332B1
(en)
|
1999-05-25 |
2004-01-13 |
Sepracor, Inc. |
Heterocyclic analgesic compounds and methods of use thereof
|
|
ATE312823T1
(de)
|
1999-07-09 |
2005-12-15 |
Boehringer Ingelheim Pharma |
Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
|
|
US7253165B2
(en)
|
1999-09-14 |
2007-08-07 |
Aventis Pharmaceuticals Inc. |
Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
|
|
WO2001046196A1
(en)
|
1999-12-21 |
2001-06-28 |
Sugen, Inc. |
4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors
|
|
OA12514A
(en)
|
1999-12-24 |
2006-05-29 |
Aventis Pharma Ltd |
Azaindoles.
|
|
GB0004149D0
(en)
|
2000-02-23 |
2000-04-12 |
Astrazeneca Uk Ltd |
Novel compounds
|
|
EP1339702A1
(en)
|
2000-03-15 |
2003-09-03 |
Warner-Lambert Company |
5-amide substituted diarylamines as mek inhibitors
|
|
AU2001247589A1
(en)
|
2000-03-20 |
2001-10-03 |
Axys Pharmaceuticals, Inc. |
Non-amidine containing protease inhibitors
|
|
SK13652002A3
(sk)
|
2000-03-31 |
2004-01-08 |
Pfizer Products Inc. |
Deriváty piperazínu
|
|
AU2001265341A1
(en)
|
2000-06-05 |
2001-12-17 |
Fmc Corporation |
Process to prepare sulfonamides
|
|
US6537994B2
(en)
|
2000-07-17 |
2003-03-25 |
Wyeth |
Heterocyclic β3 adrenergic receptor agonists
|
|
TWI262920B
(en)
|
2000-10-27 |
2006-10-01 |
Elbion Ag |
New 7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
|
|
JP4246490B2
(ja)
|
2000-11-28 |
2009-04-02 |
スミスクライン ビーチャム ピー エル シー |
オレキシン受容体のアンタゴニストとしてのモルホリン誘導体
|
|
CA2433018A1
(en)
|
2000-12-21 |
2002-06-27 |
Joel C. Barrish |
Thiazolyl inhibitors of tec family tyrosine kinases
|
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
|
DE10123129A1
(de)
|
2001-05-02 |
2002-11-14 |
Berolina Drug Dev Ab Svedala |
Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel
|
|
WO2002092087A1
(en)
|
2001-05-11 |
2002-11-21 |
Vertex Pharmaceuticals Incorporated |
2,5-disubstituted pyridine, pyrimidine, pyridazine and 1, 2, 4-triazine derivatives for use as p38 inhibitors
|
|
GB0115109D0
(en)
|
2001-06-21 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
|
SE0102809D0
(sv)
|
2001-08-22 |
2001-08-22 |
Astrazeneca Ab |
Novel compounds
|
|
US20030236293A1
(en)
|
2001-09-18 |
2003-12-25 |
Pharmacia Corporation |
Compositions of tricyclic cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
|
WO2003050102A1
(en)
|
2001-12-10 |
2003-06-19 |
Aryx Therapeutics |
Novel compounds for the treatment of cardiac arrhythmia, synthesis, and methods of use
|
|
DE10161644A1
(de)
|
2001-12-14 |
2003-06-26 |
Gruenenthal Gmbh |
N,N'-disubstituierte Piperazin-Verbindungen
|
|
US7161008B2
(en)
|
2002-05-03 |
2007-01-09 |
Sanofi - Aventis Deutschland GmbH |
Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them
|
|
CN1150176C
(zh)
|
2002-05-22 |
2004-05-19 |
上海医药工业研究院 |
芳烷酮哌嗪衍生物及其应用
|
|
NZ537156A
(en)
|
2002-05-23 |
2007-06-29 |
Cytopia Pty Ltd |
Kinase inhibitors
|
|
WO2003104216A1
(en)
*
|
2002-06-10 |
2003-12-18 |
Acadia Pharmaceuticals Inc. |
Urotensin ii receptor modulators
|
|
US20040072839A1
(en)
|
2002-06-14 |
2004-04-15 |
Amedeo Leonardi |
1-Phenylalkylpiperazines
|
|
WO2004014905A1
(en)
*
|
2002-08-08 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Substituted benzimidazole compounds
|
|
SE0202463D0
(sv)
|
2002-08-14 |
2002-08-14 |
Astrazeneca Ab |
Novel compounds
|
|
KR20120032574A
(ko)
|
2002-10-03 |
2012-04-05 |
탈자진 인코포레이티드 |
혈관항상성 유지제 및 그의 사용 방법
|
|
JP2006514102A
(ja)
|
2002-11-07 |
2006-04-27 |
アストラゼネカ アクチボラグ |
２−オキソ−エタンスルホンアミド誘導体
|
|
GB0227240D0
(en)
*
|
2002-11-21 |
2002-12-31 |
Glaxo Group Ltd |
Compounds
|
|
WO2004089914A1
(de)
|
2003-04-08 |
2004-10-21 |
Basf Aktiengesellschaft |
Benzolsulfonamid-derivate als herbizide oder desikkante/defoliante verbindungen
|
|
CA2533112A1
(en)
|
2003-08-13 |
2005-03-03 |
Christopher Hulme |
Melanin concentrating hormone receptor antagonist
|
|
US7160888B2
(en)
|
2003-08-22 |
2007-01-09 |
Warner Lambert Company Llc |
[1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
|
|
CN1897950A
(zh)
*
|
2003-10-14 |
2007-01-17 |
惠氏公司 |
稠合芳基和杂芳基衍生物及其使用方法
|
|
EP1716126B1
(en)
|
2003-12-23 |
2009-02-25 |
Eli Lilly And Company |
Morpholine derivatives as norepinephrine reuptake inhibitors
|
|
US7855214B2
(en)
*
|
2004-01-26 |
2010-12-21 |
Vertex Pharmaceuticals Incorporated |
Fused cyclic systems useful as inhibitors of TEC family protein kinases
|
|
TWI372624B
(en)
|
2004-03-30 |
2012-09-21 |
Vertex Pharma |
Azaindoles useful as inhibitors of jak and other protein kinases
|
|
US7498342B2
(en)
|
2004-06-17 |
2009-03-03 |
Plexxikon, Inc. |
Compounds modulating c-kit activity
|
|
EP1781654A1
(en)
|
2004-07-27 |
2007-05-09 |
SGX Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
US7361764B2
(en)
|
2004-07-27 |
2008-04-22 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
BRPI0514094A
(pt)
|
2004-08-02 |
2008-05-27 |
Osi Pharm Inc |
composto, composição, e, método de tratamento de distúrbio hiperproliferativo
|
|
US7820654B2
(en)
*
|
2004-09-23 |
2010-10-26 |
Dr. Reddy's Laboratories Ltd. |
Pyrimidine compounds, process for their preparation and compositions containing them
|
|
MX2007007206A
(es)
|
2004-12-14 |
2008-03-26 |
Wyeth Corp |
Uso de un agonista 5-ht6 para el tratamiento y la prevencion de trastornos neurodegenerativos.
|
|
DE102004060659A1
(de)
|
2004-12-15 |
2006-07-06 |
Lanxess Deutschland Gmbh |
Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung
|
|
AU2006204724A1
(en)
|
2005-01-14 |
2006-07-20 |
Millennium Pharmaceuticals, Inc. |
Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
|
|
US20060246099A1
(en)
|
2005-04-21 |
2006-11-02 |
L'oreal |
Compositions containing piperazine compounds
|
|
AU2006272951A1
(en)
|
2005-05-17 |
2007-02-01 |
Plexxikon, Inc. |
Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors
|
|
WO2006127587A1
(en)
*
|
2005-05-20 |
2006-11-30 |
Vertex Pharmaceuticals Incorporated |
Pyrrolopyridines useful as inhibitors of protein kinase
|
|
CA2528849C
(en)
*
|
2005-06-08 |
2014-01-14 |
Janssen Pharmaceutica N.V. |
Quinoline derivatives as antibacterial agents
|
|
GB0516156D0
(en)
|
2005-08-05 |
2005-09-14 |
Eisai London Res Lab Ltd |
JNK inhibitors
|
|
CA2624220A1
(en)
|
2005-09-29 |
2007-04-12 |
Wyeth |
1- (1h- indol- 1-yl) -3- (methylamino) -1- phenylpropan-2-ol derivatives and related compounds as modulators of the monoamine reuptake for the treatment of vasomotor symptoms (vms)
|
|
WO2007058832A2
(en)
*
|
2005-11-12 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Pyrrolo (2, 3-b) pyridine derivatives useful as tec kinase inhibitors
|
|
JP2009520831A
(ja)
*
|
2005-12-20 |
2009-05-28 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｔｅｃキナーゼインヒビター
|
|
US20070208053A1
(en)
*
|
2006-01-19 |
2007-09-06 |
Arnold Lee D |
Fused heterobicyclic kinase inhibitors
|
|
UY30121A1
(es)
*
|
2006-02-03 |
2007-08-31 |
Glaxo Group Ltd |
Nuevos compuestos
|
|
MX2008014450A
(es)
*
|
2006-05-18 |
2009-03-09 |
Mannkind Corp |
Inhibidores de cinasa intracelular.
|
|
BRPI0622054B8
(pt)
|
2006-09-22 |
2021-05-25 |
Oxford Amherst Llc |
composto e composição farmacêutica
|
|
JP5487214B2
(ja)
*
|
2008-12-19 |
2014-05-07 |
ブリストル−マイヤーズ スクイブ カンパニー |
キナーゼ阻害剤として有用なカルバゾールカルボキシアミド化合物
|