JP2009526756A5 - - Google Patents
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- JP2009526756A5 JP2009526756A5 JP2008550490A JP2008550490A JP2009526756A5 JP 2009526756 A5 JP2009526756 A5 JP 2009526756A5 JP 2008550490 A JP2008550490 A JP 2008550490A JP 2008550490 A JP2008550490 A JP 2008550490A JP 2009526756 A5 JP2009526756 A5 JP 2009526756A5
- Authority
- JP
- Japan
- Prior art keywords
- antagonist
- osmrb
- composition
- treating
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000005557 antagonist Substances 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 11
- 101150080012 OSMR gene Proteins 0.000 claims 6
- 241000124008 Mammalia Species 0.000 claims 3
- 210000003594 spinal ganglia Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 101000586302 Homo sapiens Oncostatin-M-specific receptor subunit beta Proteins 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 102100030098 Oncostatin-M-specific receptor subunit beta Human genes 0.000 claims 1
- 208000003251 Pruritus Diseases 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000003042 antagnostic effect Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 210000000944 nerve tissue Anatomy 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75797906P | 2006-01-10 | 2006-01-10 | |
| US75806606P | 2006-01-10 | 2006-01-10 | |
| US77303106P | 2006-02-14 | 2006-02-14 | |
| US80555406P | 2006-06-22 | 2006-06-22 | |
| US80555006P | 2006-06-22 | 2006-06-22 | |
| US80555206P | 2006-06-22 | 2006-06-22 | |
| US82398706P | 2006-08-30 | 2006-08-30 | |
| US82398206P | 2006-08-30 | 2006-08-30 | |
| PCT/US2007/060337 WO2007133816A2 (en) | 2006-01-10 | 2007-01-10 | Methods of treating pain and inflammation in neuronal tissue using il-31ra and osmrb antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526756A JP2009526756A (ja) | 2009-07-23 |
| JP2009526756A5 true JP2009526756A5 (enExample) | 2010-02-25 |
Family
ID=38694567
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008550488A Pending JP2009528264A (ja) | 2006-01-10 | 2007-01-10 | Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法 |
| JP2008550490A Pending JP2009526756A (ja) | 2006-01-10 | 2007-01-10 | Ｉｌ−３１ｒａアンタゴニストおよびｏｓｍｒｂアンタゴニストを用いて神経組織における疼痛および炎症を治療する方法 |
| JP2012240592A Pending JP2013047259A (ja) | 2006-01-10 | 2012-10-31 | Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008550488A Pending JP2009528264A (ja) | 2006-01-10 | 2007-01-10 | Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012240592A Pending JP2013047259A (ja) | 2006-01-10 | 2012-10-31 | Ｉｌ−３１アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (22) | US7638126B2 (enExample) |
| EP (4) | EP2594585A1 (enExample) |
| JP (3) | JP2009528264A (enExample) |
| KR (1) | KR101345586B1 (enExample) |
| AU (2) | AU2007249713A1 (enExample) |
| BR (1) | BRPI0706487A2 (enExample) |
| CA (2) | CA2633439A1 (enExample) |
| IL (4) | IL192130A0 (enExample) |
| MX (1) | MX2008008831A (enExample) |
| RU (1) | RU2565391C2 (enExample) |
| WO (2) | WO2007133816A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2135953B1 (en) | 1999-06-02 | 2014-04-23 | Chugai Seiyaku Kabushiki Kaisha | Novel hemopoietin receptor protein, Nr. 10 |
| ES2254224T3 (es) | 1999-09-27 | 2006-06-16 | Chugai Seiyaku Kabushiki Kaisha | Nueva proteina del receptor de hematopoyetina, nr12. |
| ES2377188T3 (es) * | 2002-01-18 | 2012-03-23 | Zymogenetics, Inc. | Nuevo ligando de citocina ZCYTOR17 |
| JP4927762B2 (ja) | 2005-02-14 | 2012-05-09 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−３１アンタゴニストに対するアトピー性皮膚炎の治療応答を予測する方法 |
| WO2006088855A1 (en) | 2005-02-14 | 2006-08-24 | Zymogenetics, Inc. | Methods of treating skin disorders using an il-31ra antagonist |
| BRPI0611069A2 (pt) | 2005-05-06 | 2010-11-09 | Zymogenetics Inc | anticorpo monoclonal, anticorpo humanizado, fragmento de anticorpo, uso de um antagonista, e, hibridoma |
| US20130216542A1 (en) * | 2005-05-06 | 2013-08-22 | Zymogenetics, Inc. | Variable region sequences of il-31 monoclonal antibodies and methods of use |
| US8101183B2 (en) | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
| AU2007249713A1 (en) | 2006-01-10 | 2007-11-22 | Zymogenetics, Inc. | Methods of treating pain and inflammation in neuronal tissue using IL-31Ra and OSMRb antagonists |
| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| DK2047863T3 (da) * | 2006-06-08 | 2013-09-16 | Chugai Pharmaceutical Co Ltd | Middel til forebyggelse eller behandling af inflammatoriske sygdomme |
| CN103044550A (zh) | 2006-09-01 | 2013-04-17 | 津莫吉尼蒂克斯公司 | Il-31单克隆抗体的可变区序列和使用方法 |
| US7799323B2 (en) | 2007-01-10 | 2010-09-21 | Zymogenetics, Inc. | Methods of using IL-31 to treat airway hyper-responsiveness and asthma |
| CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| EP3415529B1 (en) | 2007-09-26 | 2020-11-04 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant region |
| BRPI0821110B8 (pt) * | 2007-12-05 | 2021-05-25 | Chugai Pharmaceutical Co Ltd | anticorpo de neutralização de anti-nr10/il31ra, composição farmacêutica compreendendo o referido anticorpo e uso do mesmo |
| WO2009072598A1 (ja) | 2007-12-05 | 2009-06-11 | Chugai Seiyaku Kabushiki Kaisha | 掻痒症治療剤 |
| KR101603109B1 (ko) | 2007-12-07 | 2016-03-25 | 지모제넥틱스, 인코포레이티드 | Ｉｌ-31에 특이적인 인간화된 항체 분자 |
| EP2275443B1 (en) | 2008-04-11 | 2015-12-02 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| TWI682995B (zh) | 2009-03-19 | 2020-01-21 | 日商中外製藥股份有限公司 | 抗體恆定區域改變體 |
| WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
| EP2348128A1 (en) * | 2010-01-21 | 2011-07-27 | Sanofi | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia |
| TWI654204B (zh) | 2010-11-30 | 2019-03-21 | Chugai Seiyaku Kabushiki Kaisha | 具有鈣依存性的抗原結合能力之抗體 |
| US8790651B2 (en) | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
| US8987289B2 (en) * | 2012-12-14 | 2015-03-24 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US20140179727A1 (en) | 2012-12-14 | 2014-06-26 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US10039792B1 (en) | 2013-03-16 | 2018-08-07 | Brahm Holdings, Llc | Methods for the treatment of inflammation and pain using human birth tissue material composition |
| KR20230109779A (ko) | 2013-03-27 | 2023-07-20 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전 |
| SG11201508829QA (en) | 2013-05-30 | 2015-12-30 | Biogen Ma Inc | Oncostatin m receptor antigen binding proteins |
| EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
| MX2017009695A (es) * | 2015-01-29 | 2018-04-10 | Univ Oxford Innovation Ltd | Objetivo terapeutico y biomarcador en enfermedad inflamatoria intestinal (ibd). |
| CA2980992C (en) | 2015-04-14 | 2024-01-23 | Akihisa Kaneko | Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient |
| WO2017033951A1 (ja) * | 2015-08-24 | 2017-03-02 | 学校法人国際医療福祉大学 | 新規鎮痛剤 |
| AU2016353988B2 (en) * | 2015-11-09 | 2019-09-26 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders |
| KR20180127416A (ko) | 2016-03-17 | 2018-11-28 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
| WO2018156250A1 (en) | 2017-02-21 | 2018-08-30 | Remd Biotherapeutics, Inc. | Cancer treatment using antibodies that bind cytotoxic t-lymphocyte antigen-4 (ctla-4) |
| KR102601052B1 (ko) | 2017-02-23 | 2023-11-09 | 매직 립, 인코포레이티드 | 가변 파워 반사기를 갖는 디스플레이 시스템 |
| US10093731B2 (en) | 2017-02-24 | 2018-10-09 | Kindred Biosciences, Inc. | Anti-IL31 antibodies for veterinary use |
| JP7067800B2 (ja) * | 2017-04-12 | 2022-05-16 | 国立大学法人九州大学 | 神経障害性疼痛マーカー及びその使用 |
| WO2019178601A1 (en) | 2018-03-16 | 2019-09-19 | Zoetis Services Llc | Peptide vaccines against interleukin-31 |
| KR20250026872A (ko) | 2018-03-16 | 2025-02-25 | 조에티스 서비시즈 엘엘씨 | 수의학적 용도를 위한 인터류킨-31 단클론성 항체 |
| IL318587A (en) | 2018-07-23 | 2025-03-01 | Trevi Therapeutics Inc | Treatment of chronic cough, shortness of breath and wheezing |
| RU2707954C1 (ru) * | 2019-01-24 | 2019-12-02 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ лечения онкологической боли |
| JP6845973B1 (ja) | 2019-11-20 | 2021-03-24 | 中外製薬株式会社 | 抗体含有製剤 |
| CA3166928A1 (en) | 2020-01-10 | 2021-07-15 | Trevi Therapeutics, Inc. | Methods of administering nalbuphine |
| EP4209227A4 (en) * | 2020-09-01 | 2024-05-29 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for prevention and/or treatment of dialysis pruritus containing il-31 antagonist as active ingredient |
| US20220411518A1 (en) * | 2021-04-07 | 2022-12-29 | Galderma Holding S.A. | Treatments for prurigo nodularis |
| WO2025226834A1 (en) * | 2024-04-23 | 2025-10-30 | Attovia Therapeutics, Inc. | Il31-binding polypeptides and uses thereof |
| WO2026055142A1 (en) | 2024-09-03 | 2026-03-12 | Attovia Therapeutics, Inc. | Il13 and il31 bispecific polypeptides and uses thereof |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US750795A (en) * | 1904-02-02 | Eugene j | ||
| US4054646A (en) * | 1973-07-30 | 1977-10-18 | General Electric | Method and apparatus for detection of antibodies and antigens |
| WO1988001649A1 (en) | 1986-09-02 | 1988-03-10 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| DE69233528T2 (de) | 1991-11-25 | 2006-03-16 | Enzon, Inc. | Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen |
| US5492841A (en) * | 1994-02-18 | 1996-02-20 | E. I. Du Pont De Nemours And Company | Quaternary ammonium immunogenic conjugates and immunoassay reagents |
| US5783672A (en) | 1994-05-26 | 1998-07-21 | Immunex Corporation | Receptor for oncostatin M |
| US6074849A (en) | 1995-07-19 | 2000-06-13 | Genetics Institute, Inc. | Polynucleotides encoding human CTLA-8 related proteins |
| US5792850A (en) | 1996-05-23 | 1998-08-11 | Zymogenetics, Inc. | Hematopoietic cytokine receptor |
| ATE549918T1 (de) | 1996-12-03 | 2012-04-15 | Amgen Fremont Inc | Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden |
| RU2175874C2 (ru) * | 1999-03-17 | 2001-11-20 | Борисов Виктор Александрович | Способ лечения нарушений функций центральной нервной системы и устройство для его осуществления |
| EP2135953B1 (en) | 1999-06-02 | 2014-04-23 | Chugai Seiyaku Kabushiki Kaisha | Novel hemopoietin receptor protein, Nr. 10 |
| AU6531101A (en) | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2412211A1 (en) | 2000-06-23 | 2002-01-03 | Genetech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| US20030096339A1 (en) | 2000-06-26 | 2003-05-22 | Sprecher Cindy A. | Cytokine receptor zcytor17 |
| WO2002000721A2 (en) * | 2000-06-26 | 2002-01-03 | Zymogenetics, Inc. | Cytokine receptor zcytor17 |
| AU2001273150A1 (en) | 2000-07-20 | 2002-02-05 | Genentech Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2425169A1 (en) | 2000-10-06 | 2002-04-11 | Immunex Corporation | Hematopoietin receptors hpr1 and hpr2 |
| WO2002077230A1 (fr) | 2001-03-26 | 2002-10-03 | Chugai Seiyaku Kabushiki Kaisha | Variants d'epissage nr10 |
| ES2377188T3 (es) | 2002-01-18 | 2012-03-23 | Zymogenetics, Inc. | Nuevo ligando de citocina ZCYTOR17 |
| ES2382800T3 (es) | 2002-01-18 | 2012-06-13 | Zymogenetics, Inc. | Multímeros Zcytor17 receptores de citocinas |
| EP2110434A1 (en) | 2002-02-25 | 2009-10-21 | Genentech, Inc. | Type-1 cytokine receptor GLM-R |
| WO2006081573A2 (en) | 2005-01-28 | 2006-08-03 | Zymogenetics, Inc. | Homogeneous preparations of il-31 |
| JP4927762B2 (ja) * | 2005-02-14 | 2012-05-09 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−３１アンタゴニストに対するアトピー性皮膚炎の治療応答を予測する方法 |
| WO2006088855A1 (en) | 2005-02-14 | 2006-08-24 | Zymogenetics, Inc. | Methods of treating skin disorders using an il-31ra antagonist |
| US8101183B2 (en) * | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
| BRPI0611069A2 (pt) * | 2005-05-06 | 2010-11-09 | Zymogenetics Inc | anticorpo monoclonal, anticorpo humanizado, fragmento de anticorpo, uso de um antagonista, e, hibridoma |
| AU2007249713A1 (en) | 2006-01-10 | 2007-11-22 | Zymogenetics, Inc. | Methods of treating pain and inflammation in neuronal tissue using IL-31Ra and OSMRb antagonists |
| CN103044550A (zh) | 2006-09-01 | 2013-04-17 | 津莫吉尼蒂克斯公司 | Il-31单克隆抗体的可变区序列和使用方法 |
| US7799323B2 (en) * | 2007-01-10 | 2010-09-21 | Zymogenetics, Inc. | Methods of using IL-31 to treat airway hyper-responsiveness and asthma |
| KR101603109B1 (ko) * | 2007-12-07 | 2016-03-25 | 지모제넥틱스, 인코포레이티드 | Ｉｌ-31에 특이적인 인간화된 항체 분자 |
-
2007
- 2007-01-10 AU AU2007249713A patent/AU2007249713A1/en not_active Abandoned
- 2007-01-10 WO PCT/US2007/060337 patent/WO2007133816A2/en not_active Ceased
- 2007-01-10 CA CA002633439A patent/CA2633439A1/en not_active Withdrawn
- 2007-01-10 JP JP2008550488A patent/JP2009528264A/ja active Pending
- 2007-01-10 US US11/621,840 patent/US7638126B2/en active Active
- 2007-01-10 BR BRPI0706487-0A patent/BRPI0706487A2/pt not_active Application Discontinuation
- 2007-01-10 EP EP13154292.0A patent/EP2594585A1/en not_active Withdrawn
- 2007-01-10 RU RU2011137369/15A patent/RU2565391C2/ru active
- 2007-01-10 EP EP14161547.6A patent/EP2749571A3/en not_active Withdrawn
- 2007-01-10 CA CA2636288A patent/CA2636288C/en active Active
- 2007-01-10 WO PCT/US2007/060330 patent/WO2007143231A2/en not_active Ceased
- 2007-01-10 JP JP2008550490A patent/JP2009526756A/ja active Pending
- 2007-01-10 KR KR1020087019496A patent/KR101345586B1/ko not_active Expired - Fee Related
- 2007-01-10 US US11/621,829 patent/US7514077B2/en active Active
- 2007-01-10 MX MX2008008831A patent/MX2008008831A/es active IP Right Grant
- 2007-01-10 EP EP07777559A patent/EP2001906A2/en not_active Withdrawn
- 2007-01-10 AU AU2007254715A patent/AU2007254715B2/en not_active Ceased
- 2007-01-10 EP EP07811781A patent/EP1991581A2/en not_active Withdrawn
-
2008
- 2008-06-12 IL IL192130A patent/IL192130A0/en unknown
- 2008-06-19 IL IL192296A patent/IL192296A0/en unknown
-
2009
- 2009-02-27 US US12/395,095 patent/US7939068B2/en active Active
- 2009-10-28 US US12/607,831 patent/US7943132B2/en active Active
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2011
- 2011-03-30 US US13/075,412 patent/US8105590B2/en active Active
- 2011-03-30 US US13/075,845 patent/US8105591B2/en active Active
- 2011-12-20 US US13/331,145 patent/US8377438B2/en active Active
- 2011-12-21 US US13/332,758 patent/US8409571B2/en active Active
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2012
- 2012-05-09 IL IL219677A patent/IL219677A0/en unknown
- 2012-05-09 IL IL219678A patent/IL219678A0/en unknown
- 2012-10-31 JP JP2012240592A patent/JP2013047259A/ja active Pending
-
2013
- 2013-01-23 US US13/747,899 patent/US8637015B2/en active Active
- 2013-03-07 US US13/788,454 patent/US8685395B2/en active Active
- 2013-12-19 US US14/134,278 patent/US8968732B2/en active Active
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2014
- 2014-02-07 US US14/175,117 patent/US8974783B2/en active Active
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2015
- 2015-01-23 US US14/603,406 patent/US9334321B2/en active Active
- 2015-01-27 US US14/606,063 patent/US9334322B2/en active Active
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2016
- 2016-04-15 US US15/099,647 patent/US9631022B2/en active Active
- 2016-04-15 US US15/099,639 patent/US9631021B2/en active Active
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2017
- 2017-03-15 US US15/459,901 patent/US9834602B2/en active Active
- 2017-03-16 US US15/461,090 patent/US9828431B2/en active Active
- 2017-10-31 US US15/799,445 patent/US20180044426A1/en not_active Abandoned
- 2017-11-01 US US15/800,980 patent/US20180066050A1/en not_active Abandoned
-
2018
- 2018-12-20 US US16/227,266 patent/US20190119372A1/en not_active Abandoned
- 2018-12-20 US US16/227,307 patent/US20190112369A1/en not_active Abandoned
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