JP2009522547A5 - - Google Patents
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- Publication number
- JP2009522547A5 JP2009522547A5 JP2008548579A JP2008548579A JP2009522547A5 JP 2009522547 A5 JP2009522547 A5 JP 2009522547A5 JP 2008548579 A JP2008548579 A JP 2008548579A JP 2008548579 A JP2008548579 A JP 2008548579A JP 2009522547 A5 JP2009522547 A5 JP 2009522547A5
- Authority
- JP
- Japan
- Prior art keywords
- binding polymer
- maleic anhydride
- poly
- groups
- reactive groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000642 polymer Polymers 0.000 claims 16
- 239000000758 substrate Substances 0.000 claims 5
- 238000003556 assay Methods 0.000 claims 4
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical group O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims 4
- -1 2- (2-aminoethoxy) ethyl Chemical group 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Natural products CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 claims 2
- 239000012491 analyte Substances 0.000 claims 2
- HQABUPZFAYXKJW-UHFFFAOYSA-N butan-1-amine Chemical compound CCCCN HQABUPZFAYXKJW-UHFFFAOYSA-N 0.000 claims 2
- 235000019441 ethanol Nutrition 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 claims 2
- HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical compound CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 claims 1
- GIAFURWZWWWBQT-UHFFFAOYSA-N 2-(2-aminoethoxy)ethanol Chemical compound NCCOCCO GIAFURWZWWWBQT-UHFFFAOYSA-N 0.000 claims 1
- IWSZDQRGNFLMJS-UHFFFAOYSA-N 2-(dibutylamino)ethanol Chemical compound CCCCN(CCO)CCCC IWSZDQRGNFLMJS-UHFFFAOYSA-N 0.000 claims 1
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 claims 1
- ASUDFOJKTJLAIK-UHFFFAOYSA-N 2-methoxyethanamine Chemical compound COCCN ASUDFOJKTJLAIK-UHFFFAOYSA-N 0.000 claims 1
- JCEZOHLWDIONSP-UHFFFAOYSA-N 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine Chemical compound NCCCOCCOCCOCCCN JCEZOHLWDIONSP-UHFFFAOYSA-N 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 claims 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 claims 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 claims 1
- 229920002873 Polyethylenimine Polymers 0.000 claims 1
- 229920000147 Styrene maleic anhydride Polymers 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910021529 ammonia Inorganic materials 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229960002887 deanol Drugs 0.000 claims 1
- 125000005265 dialkylamine group Chemical group 0.000 claims 1
- 239000012972 dimethylethanolamine Substances 0.000 claims 1
- KRWWZDVIEFSIOT-UHFFFAOYSA-N ethenyl acetate;furan-2,5-dione Chemical compound CC(=O)OC=C.O=C1OC(=O)C=C1 KRWWZDVIEFSIOT-UHFFFAOYSA-N 0.000 claims 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- DILRJUIACXKSQE-UHFFFAOYSA-N n',n'-dimethylethane-1,2-diamine Chemical compound CN(C)CCN DILRJUIACXKSQE-UHFFFAOYSA-N 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- FZHAPNGMFPVSLP-UHFFFAOYSA-N silanamine Chemical compound [SiH3]N FZHAPNGMFPVSLP-UHFFFAOYSA-N 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75474705P | 2005-12-29 | 2005-12-29 | |
| US60/754,747 | 2005-12-29 | ||
| US11/448,486 | 2006-06-07 | ||
| US11/448,486 US7781203B2 (en) | 2005-12-29 | 2006-06-07 | Supports for assaying analytes and methods of making and using thereof |
| PCT/US2006/047885 WO2007078873A1 (en) | 2005-12-29 | 2006-12-15 | Supports for assaying analytes and methods of making and using thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009522547A JP2009522547A (ja) | 2009-06-11 |
| JP2009522547A5 true JP2009522547A5 (enExample) | 2012-01-19 |
| JP4903224B2 JP4903224B2 (ja) | 2012-03-28 |
Family
ID=37882445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548579A Expired - Fee Related JP4903224B2 (ja) | 2005-12-29 | 2006-12-15 | 検体アッセイのための支持体及びその製造方法及び使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7781203B2 (enExample) |
| EP (1) | EP1974214B1 (enExample) |
| JP (1) | JP4903224B2 (enExample) |
| CN (1) | CN101371139B (enExample) |
| DK (1) | DK1974214T3 (enExample) |
| WO (1) | WO2007078873A1 (enExample) |
Families Citing this family (61)
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|---|---|---|---|---|
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| KR20100039360A (ko) * | 2007-06-29 | 2010-04-15 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 펜던트 색 변화 지시제를 갖는 작용성 중합체 |
| DE102007049335A1 (de) * | 2007-10-12 | 2009-04-16 | Qiagen Gmbh | Wasserlösliche Polymere mit Chelatoren |
| US20100021954A1 (en) * | 2008-07-23 | 2010-01-28 | Sophie Deshayes | High capacity nanoparticulate immobilization surface |
| DE102007055865B3 (de) * | 2007-12-19 | 2009-10-01 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Modifizierte Multi-Well-Platte für biochemische Analysen und Zellkulturexperimente |
| US8815611B2 (en) | 2008-04-10 | 2014-08-26 | Corning Incorporated | Surface for label independent detection and method thereof |
| JP5986745B2 (ja) * | 2008-07-15 | 2016-09-06 | アカデミア シニカAcademia Sinica | Ptfe様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法 |
| EP2192410B1 (en) * | 2008-11-26 | 2012-07-11 | Corning Incorporated | Nanoparticulate affininty capture for label independent detections system |
| EP2192409B1 (en) | 2008-11-26 | 2014-04-23 | Corning Incorporated | Label independent detection biosensor composition and methods thereof |
| TWI413688B (zh) * | 2009-01-22 | 2013-11-01 | Univ Tatung | 細胞培養裝置 |
| JP5706393B2 (ja) * | 2009-03-20 | 2015-04-22 | アッタナ アクチボラゲット | その表面上に固定化細胞を含む質量応答センサーおよびそのセンサーを利用したリガンド結合の検出方法 |
| EP2233925A1 (en) | 2009-03-26 | 2010-09-29 | Corning Inc. | Immobilization method for protein having low isoelectric point |
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| US20100305289A1 (en) * | 2009-05-29 | 2010-12-02 | Jiang Dayue D | Hybrid composition and membrane based on silylated hydrophilic polymer |
| EP2435488A1 (en) * | 2009-05-29 | 2012-04-04 | Corning Inc. | Substrates for adhering, culturing and assaying cells |
| EP2467694B1 (en) * | 2009-08-21 | 2015-01-07 | Roche Diagnostics GmbH | Use of a bis-maleic anhydride cross-linking agent for fixation of a cell or tissue sample |
| CN101643321B (zh) * | 2009-09-01 | 2012-07-18 | 博奥生物有限公司 | 高分子聚合物三维氨基基片及其制备方法与应用 |
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| EP2362220A1 (en) | 2010-02-25 | 2011-08-31 | Corning Incorporated | Affinity hydrogel and label independent detection methods thereof |
| WO2011130332A1 (en) | 2010-04-12 | 2011-10-20 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US20110306148A1 (en) * | 2010-06-14 | 2011-12-15 | Siemens Healthcare Diagnostics Inc. | Composition for use as an assay reagent |
| WO2012027218A2 (en) * | 2010-08-27 | 2012-03-01 | Corning Incorporated | Peptide-modified surfaces for cell culture |
| US20120052579A1 (en) | 2010-08-27 | 2012-03-01 | Simon Kelly Shannon | Peptide-modified microcarriers for cell culture |
| CN101955320A (zh) * | 2010-08-30 | 2011-01-26 | 南京卡博生物科技有限公司 | 一种液基细胞学诊断用玻片的修饰方法 |
| US8981025B2 (en) | 2011-02-10 | 2015-03-17 | Corning Incorporated | Polymerizable catonic peptide monomers and polymers |
| WO2012162286A1 (en) | 2011-05-26 | 2012-11-29 | Corning Incorporated | High resolution label-free sensor |
| CN104321355A (zh) | 2012-02-17 | 2015-01-28 | Nvs技术股份有限公司 | 用于测定应用的聚合物支架 |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| JP6302909B2 (ja) | 2012-08-18 | 2018-03-28 | アカデミア シニカAcademia Sinica | シアリダーゼの同定および画像化のための細胞透過性プローブ |
| KR20150083859A (ko) | 2012-10-12 | 2015-07-20 | 엔브이에스 테크놀로지스 인코포레이티드 | 직교 반응성 기를 갖는 중합체 및 그의 용도 |
| SG11201507084TA (en) | 2013-03-14 | 2015-10-29 | Nvs Technologies Inc | Surface oxidation for sequestering biomolecules and related methods |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
| CN103409809A (zh) * | 2013-07-17 | 2013-11-27 | 国家纳米科学中心 | 一种小分子药物筛选芯片、其构建方法及应用 |
| WO2015006934A1 (zh) * | 2013-07-17 | 2015-01-22 | 国家纳米科学中心 | 一种小分子药物筛选芯片、其构建方法及应用 |
| CN105682666B (zh) | 2013-09-06 | 2021-06-01 | 中央研究院 | 使用醣脂激活人类iNKT细胞 |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| JP2017507118A (ja) | 2014-01-16 | 2017-03-16 | アカデミア シニカAcademia Sinica | がんの処置および検出のための組成物および方法 |
| CN106415244B (zh) | 2014-03-27 | 2020-04-24 | 中央研究院 | 反应性标记化合物及其用途 |
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| US20150344585A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
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| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
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| CA2972072A1 (en) | 2015-01-24 | 2016-07-28 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
| CN106632877B (zh) * | 2015-08-26 | 2018-10-26 | 中国科学院大连化学物理研究所 | 蛋白质固相烷基化试剂的制备及固相烷基化试剂和应用 |
| EP3389850B1 (en) * | 2015-12-18 | 2021-12-01 | 3M Innovative Properties Company | Polymeric sorbents for reactive gases |
| CN105572337A (zh) * | 2016-01-14 | 2016-05-11 | 中国科学院理化技术研究所 | 一种检测多靶标的自驱动微流体检测卡 |
| TW201808978A (zh) | 2016-03-08 | 2018-03-16 | 中央研究院 | N-聚醣及其陣列之模組化合成方法 |
| CN107202892B (zh) * | 2016-03-16 | 2019-06-04 | 广州高通生物技术有限公司 | 一种小分子芯片、其制备方法和应用 |
| EP3500594A4 (en) | 2016-08-22 | 2020-03-11 | Cho Pharma Inc. | ANTIBODIES, BINDING FRAGMENTS AND METHOD FOR USE |
| CN107227344B (zh) * | 2017-05-16 | 2019-09-24 | 北京量化健康科技有限公司 | 一种高密度、高稳定性的核酸芯片及其制备方法 |
| US20190085390A1 (en) * | 2017-09-18 | 2019-03-21 | Corning Incorporated | Flow cells having reactive surfaces for nucleic acid sequence analysis |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| WO2022033453A1 (zh) * | 2020-08-12 | 2022-02-17 | 深圳市真迈生物科技有限公司 | 氨基修饰的芯片及其制备方法和应用 |
| WO2022058845A1 (en) * | 2020-09-15 | 2022-03-24 | 3M Innovative Properties Company | Nanopatterned films with patterned surface chemistry |
| CN112079946B (zh) * | 2020-09-16 | 2021-05-18 | 南京友西科技集团股份有限公司 | 一种混凝土外加剂及其制备方法 |
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-
2006
- 2006-06-07 US US11/448,486 patent/US7781203B2/en not_active Expired - Fee Related
- 2006-12-15 WO PCT/US2006/047885 patent/WO2007078873A1/en not_active Ceased
- 2006-12-15 DK DK06839390.9T patent/DK1974214T3/da active
- 2006-12-15 CN CN2006800495277A patent/CN101371139B/zh not_active Expired - Fee Related
- 2006-12-15 EP EP06839390A patent/EP1974214B1/en not_active Not-in-force
- 2006-12-15 JP JP2008548579A patent/JP4903224B2/ja not_active Expired - Fee Related
-
2009
- 2009-01-22 US US12/357,872 patent/US7981665B2/en not_active Expired - Fee Related
-
2011
- 2011-06-09 US US13/156,902 patent/US8168399B2/en not_active Expired - Fee Related
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