JP2009502777A5 - - Google Patents
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- JP2009502777A5 JP2009502777A5 JP2008522170A JP2008522170A JP2009502777A5 JP 2009502777 A5 JP2009502777 A5 JP 2009502777A5 JP 2008522170 A JP2008522170 A JP 2008522170A JP 2008522170 A JP2008522170 A JP 2008522170A JP 2009502777 A5 JP2009502777 A5 JP 2009502777A5
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- QLJYLJGYIDIJPT-UHFFFAOYSA-N 3-(4-aminophenyl)-2-methoxypropanoic acid Chemical compound COC(C(O)=O)CC1=CC=C(N)C=C1 QLJYLJGYIDIJPT-UHFFFAOYSA-N 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims 16
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- -1 wherein R 3 is H Chemical group 0.000 claims 3
- 208000037976 chronic inflammation Diseases 0.000 claims 2
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 108060006698 EGF receptor Proteins 0.000 claims 1
- 102000001301 EGF receptor Human genes 0.000 claims 1
- 206010061968 Gastric neoplasm Diseases 0.000 claims 1
- 108010016731 PPAR gamma Proteins 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 102100038825 Peroxisome proliferator-activated receptor gamma Human genes 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000037841 lung tumor Diseases 0.000 claims 1
- 208000025402 neoplasm of esophagus Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- PSHHGHLPWFEVLB-UHFFFAOYSA-N CC(Cc1cc(N)ccc1)C(O)=O Chemical compound CC(Cc1cc(N)ccc1)C(O)=O PSHHGHLPWFEVLB-UHFFFAOYSA-N 0.000 description 2
- ZCGNGYOIRHSOJY-UHFFFAOYSA-N CCOC(C(O)=O)c(cc1)ccc1N Chemical compound CCOC(C(O)=O)c(cc1)ccc1N ZCGNGYOIRHSOJY-UHFFFAOYSA-N 0.000 description 1
- ZACJOTJQNNJIOJ-UHFFFAOYSA-N CCOC(C(O)=O)c1cc(N)ccc1 Chemical compound CCOC(C(O)=O)c1cc(N)ccc1 ZACJOTJQNNJIOJ-UHFFFAOYSA-N 0.000 description 1
- IIPURNWXORPFKN-UHFFFAOYSA-N CCOC(Cc(cc1)ccc1N)C(O)=O Chemical compound CCOC(Cc(cc1)ccc1N)C(O)=O IIPURNWXORPFKN-UHFFFAOYSA-N 0.000 description 1
- ZCPQQFGJWFYMDY-UHFFFAOYSA-N CCOC(Cc1cccc(N)c1)C(O)=O Chemical compound CCOC(Cc1cccc(N)c1)C(O)=O ZCPQQFGJWFYMDY-UHFFFAOYSA-N 0.000 description 1
- GDWALNQPKHTANB-UHFFFAOYSA-N COC(C(O)=O)c(cc1)ccc1N Chemical compound COC(C(O)=O)c(cc1)ccc1N GDWALNQPKHTANB-UHFFFAOYSA-N 0.000 description 1
- LQHYVIJCJOSMCM-UHFFFAOYSA-N COC(Cc1cccc(N)c1)C(O)=O Chemical compound COC(Cc1cccc(N)c1)C(O)=O LQHYVIJCJOSMCM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM2005A000389 | 2005-07-22 | ||
| IT000389A ITRM20050389A1 (it) | 2005-07-22 | 2005-07-22 | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| PCT/IE2006/000078 WO2007010516A2 (en) | 2005-07-22 | 2006-07-24 | Compounds and their salts specific to the ppar receptors and the egf receptors and their use in the medical field |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009502777A JP2009502777A (ja) | 2009-01-29 |
| JP2009502777A5 true JP2009502777A5 (enExample) | 2009-10-01 |
| JP5312026B2 JP5312026B2 (ja) | 2013-10-09 |
Family
ID=37579831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008522170A Active JP5312026B2 (ja) | 2005-07-22 | 2006-07-24 | Ｐｐａｒ受容体及びｅｇｆ受容体に特異的な化合物及びそれらの塩並びに医療分野におけるそれらの使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US8153841B2 (enExample) |
| EP (1) | EP1910270B3 (enExample) |
| JP (1) | JP5312026B2 (enExample) |
| KR (1) | KR101317519B1 (enExample) |
| CN (2) | CN102020577B (enExample) |
| AU (1) | AU2006271165C1 (enExample) |
| CA (1) | CA2616146C (enExample) |
| CY (1) | CY1114294T1 (enExample) |
| DK (1) | DK1910270T6 (enExample) |
| EA (2) | EA014665B3 (enExample) |
| ES (1) | ES2421260T7 (enExample) |
| HR (1) | HRP20130549T4 (enExample) |
| IL (2) | IL188878A (enExample) |
| IT (1) | ITRM20050389A1 (enExample) |
| MX (1) | MX366596B (enExample) |
| NO (1) | NO340680B1 (enExample) |
| NZ (2) | NZ592228A (enExample) |
| PL (1) | PL1910270T6 (enExample) |
| PT (1) | PT1910270E (enExample) |
| SI (1) | SI1910270T1 (enExample) |
| UA (1) | UA100359C2 (enExample) |
| WO (1) | WO2007010516A2 (enExample) |
| ZA (2) | ZA200801671B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20050389A1 (it) | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| ITRM20050390A1 (it) * | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| IE20070129A1 (en) * | 2007-02-28 | 2008-12-24 | Giuliani Int Ltd | Ppar-gamma agonists stimulate enteric defensin expression |
| ITMI20072429A1 (it) | 2007-12-24 | 2009-06-25 | Giuliani Int Ltd | Composti per il trattamento selettivo della componente immuno-infiammatoria intestinale della malattia celiaca |
| UA107562C2 (uk) * | 2008-12-05 | 2015-01-26 | Спосіб лікування псоріазу | |
| PT2805746T (pt) * | 2009-02-16 | 2020-08-17 | Nogra Pharma Ltd | Compostos de alquilamido e utilizações dos mesmos |
| CN102906074A (zh) | 2010-05-24 | 2013-01-30 | 东亚荣养株式会社 | 稠合咪唑衍生物 |
| CN116602950A (zh) * | 2012-02-09 | 2023-08-18 | 诺格拉制药有限公司 | 治疗纤维化的方法 |
| KR20150002819A (ko) | 2012-04-18 | 2015-01-07 | 노그라 파마 리미티드 | 락토스 불내증의 치료 방법 |
| FR2996545B1 (fr) | 2012-10-08 | 2016-03-25 | Ecole Polytech | Procede microfluidique de traitement et d'analyse d'une solution contenant un materiel biologique, et circuit microfluidique correspondant. |
| JP6496302B2 (ja) * | 2014-03-20 | 2019-04-03 | 京セラ株式会社 | ユーザ端末、通信制御方法及び基地局 |
| WO2017093444A1 (en) * | 2015-12-01 | 2017-06-08 | Nogra Pharma Limited | Compositions for oral administration in the treatment of inflammatory bowel disease |
| US20220000818A1 (en) | 2019-01-25 | 2022-01-06 | Nogra Pharma Limited | Compositions for use in preventing acne |
| RS66513B1 (sr) * | 2019-02-08 | 2025-03-31 | Nogra Pharma Ltd | Postupak pripreme 3-(4'-aminofenil)-2-metoksipropionske kiseli-ne i njenih analoga i intermedijera |
| WO2025132838A1 (en) | 2023-12-20 | 2025-06-26 | Nogra Pharma Limited | Acne topical formulations |
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| EP0055689B1 (de) * | 1980-12-22 | 1984-07-04 | Schering Aktiengesellschaft | In 3-Stellung substituierte 2,4,6-trihalogenierte Benzamide und deren Salze, deren Herstellung und Verwendung als Ersatzstoffe für natürliche Süssstoffe sowie Süssungsmittel auf Basis dieser Verbindungen |
| JPS58194814A (ja) | 1982-05-11 | 1983-11-12 | Nippon Shinyaku Co Ltd | 免疫調節作用を有する薬剤 |
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| ITRM20050390A1 (it) | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
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| UA107562C2 (uk) | 2008-12-05 | 2015-01-26 | Спосіб лікування псоріазу | |
| PT2805746T (pt) | 2009-02-16 | 2020-08-17 | Nogra Pharma Ltd | Compostos de alquilamido e utilizações dos mesmos |
| EP2298321A1 (en) | 2009-08-26 | 2011-03-23 | Nordic Pharma | Novel pharmaceutical compositions for treating IBD |
| CA2841358A1 (en) | 2011-07-15 | 2013-01-24 | S.L.A. Pharma Ag | Pharmaceutical compositions for rectal administration |
| EP2773378B1 (en) | 2011-10-31 | 2016-08-10 | Larsen, Claus Selch | Prodrugs of non-steroid anti-inflammatory agents (nsaids) |
| CN116602950A (zh) * | 2012-02-09 | 2023-08-18 | 诺格拉制药有限公司 | 治疗纤维化的方法 |
| KR20150002819A (ko) | 2012-04-18 | 2015-01-07 | 노그라 파마 리미티드 | 락토스 불내증의 치료 방법 |
| CN104619687A (zh) | 2012-06-01 | 2015-05-13 | 诺格拉制药有限公司 | 能够调节t-细胞应答的双环杂环及其使用方法 |
| US9013997B2 (en) | 2012-06-01 | 2015-04-21 | Broadcom Corporation | System for performing distributed data cut-through |
| HRP20181000T1 (hr) | 2012-09-13 | 2018-09-21 | Nogra Pharma Limited | Postupci liječenja stanja povezanih s kosom |
| MX2015003279A (es) | 2012-09-13 | 2015-07-06 | Nogra Pharma Ltd | Metodos para inhibir el crecimiento de vello corporal. |
| US20180193361A1 (en) | 2015-04-02 | 2018-07-12 | University Health Network | Gut anti-inflammatory agents for regulation of high blood glucose levels |
| CA2986611C (en) | 2015-06-15 | 2023-10-03 | Nmd Pharma Aps | Compounds for use in treating neuromuscular disorders |
-
2005
- 2005-07-22 IT IT000389A patent/ITRM20050389A1/it unknown
-
2006
- 2006-07-24 MX MX2013012753A patent/MX366596B/es unknown
- 2006-07-24 ES ES06766085.2T patent/ES2421260T7/es active Active
- 2006-07-24 NZ NZ592228A patent/NZ592228A/xx unknown
- 2006-07-24 SI SI200631598T patent/SI1910270T1/sl unknown
- 2006-07-24 CN CN2010105208008A patent/CN102020577B/zh active Active
- 2006-07-24 PT PT67660852T patent/PT1910270E/pt unknown
- 2006-07-24 HR HRP20130549TT patent/HRP20130549T4/hr unknown
- 2006-07-24 EP EP06766085.2A patent/EP1910270B3/en active Active
- 2006-07-24 DK DK06766085.2T patent/DK1910270T6/en active
- 2006-07-24 CN CN2006800300777A patent/CN101243039B/zh active Active
- 2006-07-24 JP JP2008522170A patent/JP5312026B2/ja active Active
- 2006-07-24 KR KR1020087003953A patent/KR101317519B1/ko active Active
- 2006-07-24 EA EA200800372A patent/EA014665B3/ru active IP Right Maintenance
- 2006-07-24 PL PL06766085T patent/PL1910270T6/pl unknown
- 2006-07-24 CA CA2616146A patent/CA2616146C/en active Active
- 2006-07-24 NZ NZ566045A patent/NZ566045A/en unknown
- 2006-07-24 WO PCT/IE2006/000078 patent/WO2007010516A2/en not_active Ceased
- 2006-07-24 AU AU2006271165A patent/AU2006271165C1/en active Active
- 2006-07-24 EA EA201000708A patent/EA017566B1/ru not_active IP Right Cessation
- 2006-07-24 UA UAA200802141A patent/UA100359C2/uk unknown
- 2006-07-24 US US11/989,090 patent/US8153841B2/en active Active
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2008
- 2008-01-17 IL IL188878A patent/IL188878A/en active IP Right Review Request
- 2008-01-18 NO NO20080325A patent/NO340680B1/no unknown
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2010
- 2010-05-26 IL IL205992A patent/IL205992A/en active IP Right Grant
- 2010-11-18 ZA ZA2010/08268A patent/ZA201008268B/en unknown
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2012
- 2012-02-29 US US13/408,439 patent/US8710100B2/en active Active
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2013
- 2013-07-05 CY CY20131100562T patent/CY1114294T1/el unknown
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2014
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2015
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2016
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