EA014665B3 - Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медицины - Google Patents
Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медициныInfo
- Publication number
- EA014665B3 EA014665B3 EA200800372A EA200800372A EA014665B3 EA 014665 B3 EA014665 B3 EA 014665B3 EA 200800372 A EA200800372 A EA 200800372A EA 200800372 A EA200800372 A EA 200800372A EA 014665 B3 EA014665 B3 EA 014665B3
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- receptors
- compounds
- medical field
- ppar
- egf
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 102000001301 EGF receptor Human genes 0.000 title 1
- 108060006698 EGF receptor Proteins 0.000 title 1
- 101150014691 PPARA gene Proteins 0.000 title 1
- 102000005962 receptors Human genes 0.000 title 1
- 108020003175 receptors Proteins 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- -1 -CFor -CFCF Chemical group 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000389A ITRM20050389A1 (it) | 2005-07-22 | 2005-07-22 | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| PCT/IE2006/000078 WO2007010516A2 (en) | 2005-07-22 | 2006-07-24 | Compounds and their salts specific to the ppar receptors and the egf receptors and their use in the medical field |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EA200800372A1 EA200800372A1 (ru) | 2008-06-30 |
| EA014665B1 EA014665B1 (ru) | 2010-12-30 |
| EA014665B3 true EA014665B3 (ru) | 2016-09-30 |
Family
ID=37579831
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200800372A EA014665B3 (ru) | 2005-07-22 | 2006-07-24 | Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медицины |
| EA201000708A EA017566B1 (ru) | 2005-07-22 | 2006-07-24 | Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медицины |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201000708A EA017566B1 (ru) | 2005-07-22 | 2006-07-24 | Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медицины |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US8153841B2 (enExample) |
| EP (1) | EP1910270B3 (enExample) |
| JP (1) | JP5312026B2 (enExample) |
| KR (1) | KR101317519B1 (enExample) |
| CN (2) | CN102020577B (enExample) |
| AU (1) | AU2006271165C1 (enExample) |
| CA (1) | CA2616146C (enExample) |
| CY (1) | CY1114294T1 (enExample) |
| DK (1) | DK1910270T6 (enExample) |
| EA (2) | EA014665B3 (enExample) |
| ES (1) | ES2421260T7 (enExample) |
| HR (1) | HRP20130549T4 (enExample) |
| IL (2) | IL188878A (enExample) |
| IT (1) | ITRM20050389A1 (enExample) |
| MX (1) | MX366596B (enExample) |
| NO (1) | NO340680B1 (enExample) |
| NZ (2) | NZ566045A (enExample) |
| PL (1) | PL1910270T6 (enExample) |
| PT (1) | PT1910270E (enExample) |
| SI (1) | SI1910270T1 (enExample) |
| UA (1) | UA100359C2 (enExample) |
| WO (1) | WO2007010516A2 (enExample) |
| ZA (2) | ZA200801671B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20050390A1 (it) | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| ITRM20050389A1 (it) | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
| IE20070129A1 (en) * | 2007-02-28 | 2008-12-24 | Giuliani Int Ltd | Ppar-gamma agonists stimulate enteric defensin expression |
| ITMI20072429A1 (it) | 2007-12-24 | 2009-06-25 | Giuliani Int Ltd | Composti per il trattamento selettivo della componente immuno-infiammatoria intestinale della malattia celiaca |
| UA107562C2 (uk) * | 2008-12-05 | 2015-01-26 | Спосіб лікування псоріазу | |
| EA020856B1 (ru) * | 2009-02-16 | 2015-02-27 | Джулиани Интернэшнл Лимитед | Способы лечения патологических состояний, связанных с волосами |
| WO2011148956A1 (ja) | 2010-05-24 | 2011-12-01 | トーアエイヨー株式会社 | 縮合イミダゾール誘導体 |
| JP6301844B2 (ja) | 2012-02-09 | 2018-03-28 | ノグラ ファーマ リミテッド | 線維症の処置方法 |
| EP2844242A1 (en) | 2012-04-18 | 2015-03-11 | Nogra Pharma Limited | Methods of treating lactose intolerance |
| FR2996545B1 (fr) | 2012-10-08 | 2016-03-25 | Ecole Polytech | Procede microfluidique de traitement et d'analyse d'une solution contenant un materiel biologique, et circuit microfluidique correspondant. |
| JP6496302B2 (ja) * | 2014-03-20 | 2019-04-03 | 京セラ株式会社 | ユーザ端末、通信制御方法及び基地局 |
| WO2017093444A1 (en) * | 2015-12-01 | 2017-06-08 | Nogra Pharma Limited | Compositions for oral administration in the treatment of inflammatory bowel disease |
| WO2020152350A1 (en) | 2019-01-25 | 2020-07-30 | Nogra Pharma Limited | Compositions for use in preventing acne |
| EP3921299B1 (en) | 2019-02-08 | 2024-11-20 | Nogra Pharma Limited | Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof |
| WO2025132838A1 (en) | 2023-12-20 | 2025-06-26 | Nogra Pharma Limited | Acne topical formulations |
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|---|---|---|---|---|
| EP0055689A1 (de) * | 1980-12-22 | 1982-07-07 | Schering Aktiengesellschaft | In 3-Stellung substituierte 2,4,6-trihalogenierte Benzamide und deren Salze, deren Herstellung und Verwendung als Ersatzstoffe für natürliche Süssstoffe sowie Süssungsmittel auf Basis dieser Verbindungen |
| EP1285908A1 (en) * | 2000-05-29 | 2003-02-26 | Kyorin Pharmaceutical Co., Ltd. | Substituted phenylpropionic acid derivatives |
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| ITRM20050390A1 (it) | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
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| ITMI20072429A1 (it) | 2007-12-24 | 2009-06-25 | Giuliani Int Ltd | Composti per il trattamento selettivo della componente immuno-infiammatoria intestinale della malattia celiaca |
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| UA107562C2 (uk) | 2008-12-05 | 2015-01-26 | Спосіб лікування псоріазу | |
| EA020856B1 (ru) | 2009-02-16 | 2015-02-27 | Джулиани Интернэшнл Лимитед | Способы лечения патологических состояний, связанных с волосами |
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