UA86077C2 - Cetp inhibitors - Google Patents

Cetp inhibitors

Info

Publication number
UA86077C2
UA86077C2 UAA200701058A UAA200701058A UA86077C2 UA 86077 C2 UA86077 C2 UA 86077C2 UA A200701058 A UAA200701058 A UA A200701058A UA A200701058 A UAA200701058 A UA A200701058A UA 86077 C2 UA86077 C2 UA 86077C2
Authority
UA
Ukraine
Prior art keywords
compounds
ring
cetp inhibitors
benzoheterocyclic
formula
Prior art date
Application number
UAA200701058A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Амджад Али
Джоанн М. Наполитано
Сяолин Ден
Чжицзянь Лу
Питер Дж. Синклер
Гейл Э. Тейлор
Кристофер Ф. Томпсон
Назя Курайши
Камерон Дж. Смит
Джулиан А. Хант
Original Assignee
Мерк Энд Ко., Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.
Publication of UA86077C2 publication Critical patent/UA86077C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-choleslerol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1 В or Ris a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5 membered ring has an aromalic, helerocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a -CH-.І
UAA200701058A 2004-07-02 2005-07-01 Cetp inhibitors UA86077C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58527404P 2004-07-02 2004-07-02

Publications (1)

Publication Number Publication Date
UA86077C2 true UA86077C2 (en) 2009-03-25

Family

ID=38131543

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200701058A UA86077C2 (en) 2004-07-02 2005-07-01 Cetp inhibitors

Country Status (5)

Country Link
CN (1) CN1980904A (en)
HN (1) HN2005000340A (en)
TN (1) TNSN06456A1 (en)
UA (1) UA86077C2 (en)
ZA (1) ZA200610565B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101212966B (en) * 2005-07-01 2012-03-14 默沙东公司 Process for synthesizing a CETP inhibitor
CN101412711A (en) * 2007-10-15 2009-04-22 上海恒瑞医药有限公司 Carbamate derivatives and use thereof in medicine
CN103269592B (en) * 2010-10-29 2016-05-11 默沙东公司 Cyclammonium replaces oxazolidone CETP inhibitor
JP6030147B2 (en) * 2011-11-30 2016-11-24 デウン ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for preventing or treating hypertriglyceridemia or diseases associated with hypertriglyceridemia
CN102516237B (en) * 2011-12-05 2014-02-26 成都苑东药业有限公司 Oxazolidinone derivative
CN102603499A (en) * 2012-03-01 2012-07-25 南京药石药物研发有限公司 Synthetic method of 1-bromo-4-fluorin-5-isopropyl-2-metoxybenzene
CN116078377B (en) * 2023-03-06 2023-06-27 泽升科技(广州)有限公司 Production process for preparing deuterated benzene by using supported catalyst

Also Published As

Publication number Publication date
TNSN06456A1 (en) 2008-02-22
HN2005000340A (en) 2009-11-06
CN1980904A (en) 2007-06-13
ZA200610565B (en) 2008-07-30

Similar Documents

Publication Publication Date Title
MX2007000035A (en) Cetp inhibitors.
ATE533485T1 (en) CETP INHIBITORS
WO2007081569A3 (en) Cetp inhibitors
WO2007081571A3 (en) Cetp inhibitors
MY139887A (en) Tetrahydronaphthyridine derivatives and a process for preparing the same.
WO2005095409A3 (en) Tetrahydroquinoline derivatives and a process for preparing the same
WO2007081570A3 (en) Cholesteryl ester transfer protein inhibitors
UA86077C2 (en) Cetp inhibitors
EP1726584A4 (en) 2-aminoquinazoline derivative
WO2007079186A3 (en) 1, 3-oxazolidin-2-one derivatives useful as cetp inhibitors
WO2006109075A3 (en) Hydroxybenzamide derivatives and their use as inhibitors of hsp90
MX2007004699A (en) Indole and benzimidazole derivatives.
ATE404536T1 (en) SUBSTITUTED QUINOLINE DERIVATIVES AS INHIBITORS OF MITOTIC KINESIN
MX2013004407A (en) Pyridine derivative and medicinal agent.
RS52700B (en) Substituted oxindole derivative and its use as a vasopressin receptor ligand
MX2009011769A (en) Pyridone derivatives as p38a mapk inhibitors.
MX2008013728A (en) Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof.
WO2008093674A1 (en) Novel thiadiazole derivative having kinase inhibitory activity
ATE396183T1 (en) CHROMEAND DERIVATIVES AND THEIR USE AS LIGANDS OF THE 5-HT RECEPTOR
UA107689C2 (en) 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES
WO2007047591A3 (en) Cetp inhibitors
TW200738697A (en) Benzimidazole derivatives as 5-HT6,5-HT24
EP1832584A4 (en) Pyrimidinylisoxazol derivative
EA201270360A1 (en) THERAPEUTIC MEANS FROM ALARM DISORDERS
DE502007003971D1 (en) 3,4 DIAMINOPYRIDINE DERIVATIVES