TNSN06456A1 - Cetp inhibitors - Google Patents
Cetp inhibitorsInfo
- Publication number
- TNSN06456A1 TNSN06456A1 TNP2006000456A TNSN06456A TNSN06456A1 TN SN06456 A1 TNSN06456 A1 TN SN06456A1 TN P2006000456 A TNP2006000456 A TN P2006000456A TN SN06456 A TNSN06456 A TN SN06456A TN SN06456 A1 TNSN06456 A1 TN SN06456A1
- Authority
- TN
- Tunisia
- Prior art keywords
- compounds
- ring
- cetp inhibitors
- benzocycloalky
- benzoheterocyclic
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: In the compounds of Formula I, B or R2 is a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalky substituent, and one other position on the 5-membered ring has an aromatic, heterocyclic, cycloalkyl, benzoheterocyclic or benzocycloalky substituent connected directly to the ring or attached to the ring through a -CH2-.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58527404P | 2004-07-02 | 2004-07-02 | |
| PCT/US2005/023546 WO2006014357A1 (en) | 2004-07-02 | 2005-07-01 | Cetp inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN06456A1 true TNSN06456A1 (en) | 2008-02-22 |
Family
ID=38131543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2006000456A TNSN06456A1 (en) | 2004-07-02 | 2006-12-29 | Cetp inhibitors |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1980904A (en) |
| HN (1) | HN2005000340A (en) |
| TN (1) | TNSN06456A1 (en) |
| UA (1) | UA86077C2 (en) |
| ZA (1) | ZA200610565B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101212966B (en) * | 2005-07-01 | 2012-03-14 | 默沙东公司 | Process for synthesizing a CETP inhibitor |
| CN101412711A (en) * | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | Carbamate derivatives and use thereof in medicine |
| WO2012058187A1 (en) * | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | Cyclic amine substituted oxazolidinone cetp inhibitor |
| US9486443B2 (en) * | 2011-11-30 | 2016-11-08 | Daewoong Pharmaceutical Co., Ltd. | Pharmaceutical composition for preventing or treating hypertriglyceridemia or hypertriglyceridemia-associated diseases |
| CN102516237B (en) * | 2011-12-05 | 2014-02-26 | 成都苑东药业有限公司 | Oxazolidinone derivative |
| CN102603499A (en) * | 2012-03-01 | 2012-07-25 | 南京药石药物研发有限公司 | Synthetic method of 1-bromo-4-fluorin-5-isopropyl-2-metoxybenzene |
| CN116078377B (en) * | 2023-03-06 | 2023-06-27 | 泽升科技(广州)有限公司 | Production process for preparing deuterated benzene by using supported catalyst |
-
2005
- 2005-06-29 HN HN2005000340A patent/HN2005000340A/en unknown
- 2005-07-01 UA UAA200701058A patent/UA86077C2/en unknown
- 2005-07-01 CN CNA2005800226187A patent/CN1980904A/en active Pending
-
2006
- 2006-12-15 ZA ZA200610565A patent/ZA200610565B/en unknown
- 2006-12-29 TN TNP2006000456A patent/TNSN06456A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200610565B (en) | 2008-07-30 |
| UA86077C2 (en) | 2009-03-25 |
| CN1980904A (en) | 2007-06-13 |
| HN2005000340A (en) | 2009-11-06 |
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