JP2009500432A - 人参総二次配糖体医薬組成物及びその製造方法と応用 - Google Patents

人参総二次配糖体医薬組成物及びその製造方法と応用 Download PDF

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Publication number
JP2009500432A
JP2009500432A JP2008520691A JP2008520691A JP2009500432A JP 2009500432 A JP2009500432 A JP 2009500432A JP 2008520691 A JP2008520691 A JP 2008520691A JP 2008520691 A JP2008520691 A JP 2008520691A JP 2009500432 A JP2009500432 A JP 2009500432A
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ginseng
ginsenoside
secondary glycoside
total
pharmaceutical composition
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JP2008520691A
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English (en)
Japanese (ja)
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JP2009500432A5 (enExample
Inventor
コンシン サン
ハーシュン ルオ
ヨンリ チャオ
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中国医▲薬▼研究▲開▼▲発▼中心有限公司
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Priority claimed from CN 200510083852 external-priority patent/CN1718191A/zh
Priority claimed from CNB2005100838556A external-priority patent/CN100337636C/zh
Priority claimed from CN 200510083854 external-priority patent/CN1718193A/zh
Application filed by 中国医▲薬▼研究▲開▼▲発▼中心有限公司 filed Critical 中国医▲薬▼研究▲開▼▲発▼中心有限公司
Publication of JP2009500432A publication Critical patent/JP2009500432A/ja
Publication of JP2009500432A5 publication Critical patent/JP2009500432A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2008520691A 2005-07-14 2006-07-05 人参総二次配糖体医薬組成物及びその製造方法と応用 Pending JP2009500432A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN 200510083852 CN1718191A (zh) 2005-07-14 2005-07-14 人参总次苷口腔崩解片及其制备方法和应用
CNB2005100838556A CN100337636C (zh) 2005-07-14 2005-07-14 一种人参总次苷药物组合物及其制备方法和应用
CN 200510083854 CN1718193A (zh) 2005-07-14 2005-07-14 一种人参总次苷药物组合物及其制法和在制备治疗心肌缺血及失血性休克药物中的应用
PCT/CN2006/001574 WO2007006208A1 (en) 2005-07-14 2006-07-05 Medicinal composition containing ginseng secondary glycosides, its preparation method and application

Publications (2)

Publication Number Publication Date
JP2009500432A true JP2009500432A (ja) 2009-01-08
JP2009500432A5 JP2009500432A5 (enExample) 2013-05-23

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JP2008520691A Pending JP2009500432A (ja) 2005-07-14 2006-07-05 人参総二次配糖体医薬組成物及びその製造方法と応用

Country Status (8)

Country Link
US (1) US7973014B2 (enExample)
EP (1) EP1905444B1 (enExample)
JP (1) JP2009500432A (enExample)
KR (1) KR101182917B1 (enExample)
CA (1) CA2614700C (enExample)
ES (1) ES2515891T3 (enExample)
PL (1) PL1905444T3 (enExample)
WO (1) WO2007006208A1 (enExample)

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JP2011016792A (ja) * 2009-06-12 2011-01-27 Lion Corp 尿酸値低下組成物
WO2011077800A1 (ja) * 2009-12-21 2011-06-30 ライオン株式会社 高脂血症改善剤、並びに、貧血改善組成物、尿酸値低下組成物及び飲食品
JP2014024832A (ja) * 2012-06-19 2014-02-06 Kao Corp Ｃｇｒｐ応答性促進剤
JP2014114220A (ja) * 2012-12-06 2014-06-26 Kao Corp Ｃｇｒｐ応答性促進剤
JP2015516990A (ja) * 2013-04-28 2015-06-18 フージェン サウス ファーマシューティカル カンパニー，リミティド サポニンナノミセル、並びにその調製方法、応用及び医薬組成物
JP2017528482A (ja) * 2015-07-16 2017-09-28 インテリジェント シンセティック バイオロジー センター 血管漏出症候群の予防または治療用組成物

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RU2463070C1 (ru) * 2008-07-23 2012-10-10 Хэбэй Илин Медицин Рисёч Инститьют Ко., Лтд. Фармацевтическая композиция для регуляции калиевых каналов в клетке сердечной мышцы, способ ее получения и ее применения
KR100919134B1 (ko) * 2008-10-22 2009-09-25 (주)해나천연물연구소 항비만 효능을 나타내는 저극성 진세노사이드를 고농도로 함유하는 인삼 추출물 및 이의 제조방법
KR101011254B1 (ko) * 2008-12-10 2011-01-27 건국대학교 산학협력단 과염소산의 산 가수분해를 이용한 진세노사이드 아글리콘 프로토파낙사디올 제조방법
CN102600214B (zh) * 2011-01-24 2014-10-08 北京大学 苦丁茶冬青叶的提取方法、总皂苷及其用途
CN102731603A (zh) * 2011-03-31 2012-10-17 上海兰蒂斯生物医药科技有限公司 人参二醇及20(r)-原人参二醇的制备方法
ES2800315T3 (es) 2011-08-19 2020-12-29 Acquascience Ltd Composición para separar proteínas de detergentes y detección de proteínas
CN103372138B (zh) * 2012-04-25 2017-07-28 天士力制药集团股份有限公司 一种含有生脉饮有效成分的药物组合物及其制备方法
CN103242408B (zh) * 2013-05-08 2016-01-13 天津大学 微波辅助技术提取人参皂苷单体Rg3和Rh2的方法
CN105055801A (zh) * 2015-08-28 2015-11-18 霍同颜 一种医治心律失常的组合物及制法
CN108339000B (zh) * 2017-01-22 2021-08-03 上海弘医堂生物医药科技有限公司 一种人参属植物提取物及其药物组合物和应用
KR102095536B1 (ko) 2019-06-04 2020-03-31 (주)녹십자웰빙 천연물 추출물의 용출률 및 붕해성이 개선된 경구용 제제
CN111228277B (zh) * 2020-03-11 2023-07-07 大连大学 20(R)-25-羟基-达玛烷型-3β,12β,20-三醇的药物用途
CN111802613B (zh) * 2020-07-14 2022-10-11 广东老中医保健食品有限公司 人参皂苷掩味剂、含人参皂苷的具留长麦香风味组合物、口含片及其制作方法
CN112646081A (zh) * 2020-12-07 2021-04-13 石河子大学 新型硼酸功能化大孔树脂的制备以及在甜菊糖苷选择吸附中的应用
CN114910573A (zh) * 2021-02-10 2022-08-16 陕西中医药大学附属医院 一种用于体外细胞培养的中药含药血清制备及鉴定方法
CN113331421A (zh) * 2021-06-22 2021-09-03 北京澳特舒尔保健品开发有限公司 总皂苷的制备方法及其在改善睡眠、祛斑产品中的应用
CN116120389B (zh) * 2023-03-29 2023-07-18 中国农业科学院特产研究所 人参皂苷Rg5及制备和在制备过敏性鼻炎药物中的应用
CN116999449B (zh) * 2023-08-17 2024-05-03 吉林农业大学 一种人参皂苷组合物及其在制备多靶点脂肪细胞发育分化和代谢调节剂中的应用
CN117323270B (zh) * 2023-11-29 2024-03-19 江西康一参生物科技有限公司 一种抗炎症多功效的人参组合物及其应用

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011016792A (ja) * 2009-06-12 2011-01-27 Lion Corp 尿酸値低下組成物
WO2011077800A1 (ja) * 2009-12-21 2011-06-30 ライオン株式会社 高脂血症改善剤、並びに、貧血改善組成物、尿酸値低下組成物及び飲食品
JP2011126852A (ja) * 2009-12-21 2011-06-30 Lion Corp 貧血改善組成物及び飲食品
US8927033B2 (en) 2009-12-21 2015-01-06 Lion Corporation Hyperlipemia-ameliorating agent, anemia-ameliorating composition, uric-acid-level-reducing composition, and food or beverage
JP2014024832A (ja) * 2012-06-19 2014-02-06 Kao Corp Ｃｇｒｐ応答性促進剤
JP2014114220A (ja) * 2012-12-06 2014-06-26 Kao Corp Ｃｇｒｐ応答性促進剤
JP2015516990A (ja) * 2013-04-28 2015-06-18 フージェン サウス ファーマシューティカル カンパニー，リミティド サポニンナノミセル、並びにその調製方法、応用及び医薬組成物
JP2017528482A (ja) * 2015-07-16 2017-09-28 インテリジェント シンセティック バイオロジー センター 血管漏出症候群の予防または治療用組成物

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Publication number Publication date
EP1905444B1 (en) 2014-09-24
US7973014B2 (en) 2011-07-05
US20080234208A1 (en) 2008-09-25
ES2515891T3 (es) 2014-10-30
CA2614700C (en) 2011-07-19
KR101182917B1 (ko) 2012-09-13
CA2614700A1 (en) 2007-01-18
PL1905444T3 (pl) 2015-03-31
WO2007006208A1 (en) 2007-01-18
EP1905444A1 (en) 2008-04-02
HK1110520A1 (en) 2008-07-18
EP1905444A4 (en) 2011-11-30
KR20080034154A (ko) 2008-04-18

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