JP2008538282A5 - - Google Patents
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- JP2008538282A5 JP2008538282A5 JP2008505508A JP2008505508A JP2008538282A5 JP 2008538282 A5 JP2008538282 A5 JP 2008538282A5 JP 2008505508 A JP2008505508 A JP 2008505508A JP 2008505508 A JP2008505508 A JP 2008505508A JP 2008538282 A5 JP2008538282 A5 JP 2008538282A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- sample
- cancer
- egfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66841505P | 2005-04-05 | 2005-04-05 | |
| US70383305P | 2005-07-29 | 2005-07-29 | |
| US11/323,946 US20070026415A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/322,790 US20070026413A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/323,962 US20070026417A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/324,041 US20070026418A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11/323,945 US20070026414A1 (en) | 2005-07-29 | 2005-12-29 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| PCT/US2006/012778 WO2006108087A2 (en) | 2005-04-05 | 2006-04-05 | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008538282A JP2008538282A (ja) | 2008-10-23 |
| JP2008538282A5 true JP2008538282A5 (enExample) | 2010-10-14 |
Family
ID=37074090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008505508A Pending JP2008538282A (ja) | 2005-04-05 | 2006-04-05 | 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20070099207A1 (enExample) |
| EP (2) | EP1874920A4 (enExample) |
| JP (1) | JP2008538282A (enExample) |
| GB (1) | GB2427468B (enExample) |
| WO (1) | WO2006108087A2 (enExample) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| WO2006078470A2 (en) | 2005-01-18 | 2006-07-27 | Biocept, Inc. | Cell separation using microchannel having patterned posts |
| US20060252087A1 (en) * | 2005-01-18 | 2006-11-09 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| US20090136982A1 (en) * | 2005-01-18 | 2009-05-28 | Biocept, Inc. | Cell separation using microchannel having patterned posts |
| US8158410B2 (en) | 2005-01-18 | 2012-04-17 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070059716A1 (en) * | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
| US20070059718A1 (en) * | 2005-09-15 | 2007-03-15 | Mehmet Toner | Systems and methods for enrichment of analytes |
| US20110052570A1 (en) * | 2005-10-26 | 2011-03-03 | Children's Medical Center Corporation | Method to prognose response to anti-egfr therapeutics |
| US7695956B2 (en) | 2006-01-12 | 2010-04-13 | Biocept, Inc. | Device for cell separation and analysis and method of using |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US20080124721A1 (en) * | 2006-06-14 | 2008-05-29 | Martin Fuchs | Analysis of rare cell-enriched samples |
| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| EP2029779A4 (en) | 2006-06-14 | 2010-01-20 | Living Microsystems Inc | HIGHLY PARALLEL SNP GENOTYPING UTILIZATION FOR FETAL DIAGNOSIS |
| US20080007838A1 (en) * | 2006-07-07 | 2008-01-10 | Omnitech Partners, Inc. | Field-of-view indicator, and optical system and associated method employing the same |
| US8014577B2 (en) * | 2007-01-29 | 2011-09-06 | Institut National D'optique | Micro-array analysis system and method thereof |
| US8999634B2 (en) | 2007-04-27 | 2015-04-07 | Quest Diagnostics Investments Incorporated | Nucleic acid detection combining amplification with fragmentation |
| WO2008153692A2 (en) * | 2007-05-22 | 2008-12-18 | The Brigham And Women's Hospital, Inc. | Microrna expression profiling of cerebrospinal fluid |
| JP2010536565A (ja) * | 2007-08-23 | 2010-12-02 | シンベニオ・バイオシステムズ・インコーポレーテッド | 目標種用のトラップ用磁気選別システム |
| US8008032B2 (en) | 2008-02-25 | 2011-08-30 | Cellective Dx Corporation | Tagged ligands for enrichment of rare analytes from a mixed sample |
| WO2009140326A2 (en) | 2008-05-16 | 2009-11-19 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Microfluidic isolation of tumor cells or other rare cells from whole blood or other liquids |
| US20110201003A1 (en) * | 2008-08-08 | 2011-08-18 | Eisai R&D Management Co., Ltd. | Method for obtaining purkinje progenitor cell by using neph3(65b13) and e-cadherin |
| ES2620012T3 (es) | 2008-09-20 | 2017-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnóstico no invasivo de la aneuploidia fetal por secuenciación |
| US20110212440A1 (en) * | 2008-10-10 | 2011-09-01 | Cnrs-Dae | Cell sorting device |
| EP2389455A4 (en) * | 2009-01-26 | 2012-12-05 | Verinata Health Inc | METHODS AND COMPOSITIONS FOR IDENTIFYING A FETAL CELL |
| US20120270209A1 (en) * | 2009-05-15 | 2012-10-25 | Massachusetts Institute Of Technology | Systems, devices, and methods for specific capture and release of biological sample components |
| FR2946895A1 (fr) * | 2009-06-19 | 2010-12-24 | Commissariat Energie Atomique | Systeme microfluidique et procede correspondant pour le transfert d'elements entre phases liquides et utilisation de ce systeme pour extraire ces elements |
| JP6048660B2 (ja) * | 2009-09-21 | 2016-12-21 | ランジュ ラルハン | 甲状腺癌を診断および処置するための方法および組成物 |
| WO2011063416A2 (en) | 2009-11-23 | 2011-05-26 | The General Hospital Corporation | Microfluidic devices for the capture of biological sample components |
| WO2012002447A1 (ja) * | 2010-06-30 | 2012-01-05 | 武田薬品工業株式会社 | 変異ポリヌクレオチドの検出方法 |
| CN102140518B (zh) * | 2011-01-18 | 2013-02-06 | 杭州迪安医学检验中心有限公司 | 肺癌相关表皮生长因子受体egfr外显子突变定量检测试剂盒及方法 |
| CN103562728B (zh) * | 2011-03-24 | 2016-08-17 | 安派科生物医学科技有限公司 | 用于疾病检测的微器件 |
| SG194064A1 (en) * | 2011-04-08 | 2013-11-29 | Panasonic Corp | Diagnosis kit and method of using the same |
| CN103608682B (zh) * | 2011-05-05 | 2017-01-18 | 安派科生物医学科技有限公司 | 肿瘤细胞检测仪 |
| CN110763842A (zh) | 2011-06-29 | 2020-02-07 | 中央研究院 | 使用表面涂层对生物物质的捕获、纯化和释放 |
| WO2013116523A1 (en) * | 2012-01-31 | 2013-08-08 | The Regents Of The University Of Michigan | Circulating tumor cell capturing techniques and devices |
| US9555382B2 (en) | 2012-02-16 | 2017-01-31 | National Research Council Of Canada | Centrifugal microfluidic mixing apparatus with deflection element, and method of mixing |
| WO2013131411A1 (en) * | 2012-03-08 | 2013-09-12 | Chang He Bio-Medical Science(Yangzhou) Co.,Ltd. | Micro-devices for improved disease detection |
| CN105209489B (zh) | 2013-03-05 | 2019-06-14 | 得克萨斯州大学系统董事会 | 针对间质和上皮-间质转化的循环肿瘤细胞的特异性检测工具 |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| EP3608022A1 (en) | 2013-03-15 | 2020-02-12 | The Trustees of Princeton University | Methods and devices for high throughput purification |
| US12590955B2 (en) | 2013-03-15 | 2026-03-31 | Zeon Corporation | Methods and systems for processing particles |
| EP2971287B1 (en) | 2013-03-15 | 2019-08-14 | GPB Scientific, LLC | On-chip microfluidic processing of particles |
| WO2015010019A1 (en) | 2013-07-18 | 2015-01-22 | The General Hospital Corporation | Selective capture and release of rare mammalian cells using photodegradable hydrogels in a microfluidic platform |
| KR102113310B1 (ko) * | 2013-09-03 | 2020-05-20 | 아주대학교 산학협력단 | 암 세포 분리용 조성물, 키트 및 이를 이용한 분리 방법 |
| EP3060680B1 (en) | 2013-10-21 | 2019-02-27 | The General Hospital Corporation | Methods relating to circulating tumor cell clusters and the treatment of cancer |
| JP2014158468A (ja) * | 2014-03-05 | 2014-09-04 | Clinical Genomics Pty Ltd | 検出方法 |
| CN106662514A (zh) | 2014-04-01 | 2017-05-10 | 中央研究院 | 用于癌症诊断及预后的方法和系统 |
| EP3132267B1 (en) * | 2014-04-17 | 2019-08-14 | Siemens Healthcare Diagnostics Inc. | Method to screen out false positives in a circulating tumor cell assay |
| US10502674B2 (en) * | 2014-06-27 | 2019-12-10 | The Regents Of The University Of California | Apparatus and method for label-free analysis of rare cells from bodily fluids |
| JP6339432B2 (ja) * | 2014-07-16 | 2018-06-06 | オリンパス株式会社 | 細胞観察情報処理システム、細胞観察情報処理方法、細胞観察情報処理プログラム |
| CN105381824B (zh) | 2014-08-26 | 2019-04-23 | 中央研究院 | 收集器架构布局设计 |
| US10656157B2 (en) * | 2014-09-24 | 2020-05-19 | Purdue Research Foundation | Rare event detection using mass tags |
| CN107407626B (zh) * | 2014-09-26 | 2020-10-30 | 加利福尼亚大学董事会 | 评估癌症的疾病状况的方法 |
| EP3215270B1 (en) * | 2014-11-03 | 2020-05-27 | The General Hospital Corporation | Concentrating particles in a microfluidic device |
| US10304188B1 (en) | 2015-03-27 | 2019-05-28 | Caleb J. Kumar | Apparatus and method for automated cell analysis |
| JP6615499B2 (ja) * | 2015-06-05 | 2019-12-04 | 国立大学法人 東京大学 | 細胞またはリポソーム粒子の分離捕捉装置 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| CN108778508B (zh) * | 2016-01-14 | 2022-09-13 | 欧洲分子生物学实验室 | 配体诱导的细胞表达的微流体分析 |
| KR20170099738A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 패치 및 그 제조 방법 |
| KR102478639B1 (ko) | 2016-02-23 | 2022-12-19 | 노을 주식회사 | 표지 물질을 저장하는 패치, 이를 이용하는 조직 진단 방법 및 장치 |
| US10371610B2 (en) | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
| KR102045068B1 (ko) * | 2016-02-23 | 2019-11-15 | 노을 주식회사 | 중합 효소 연쇄 반응 패치, 이를 이용하는 진단 방법 및 장치 |
| KR102406596B1 (ko) * | 2016-02-23 | 2022-06-10 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
| US10107726B2 (en) | 2016-03-16 | 2018-10-23 | Cellmax, Ltd. | Collection of suspended cells using a transferable membrane |
| US10010883B2 (en) * | 2016-09-20 | 2018-07-03 | International Business Machines Corporation | Deterministic lateral displacement arrays |
| JP6518985B2 (ja) * | 2016-09-29 | 2019-05-29 | 住友ゴム工業株式会社 | がん細胞捕捉方法 |
| JP6779483B2 (ja) | 2016-09-29 | 2020-11-04 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
| CN110381961A (zh) * | 2016-10-24 | 2019-10-25 | Gpb科学有限责任公司 | 用于治疗用途的细胞和组合物的制备中的确定性侧向位移 |
| CN107041361A (zh) * | 2017-04-20 | 2017-08-15 | 北京奥康华医学检验所有限公司 | 一种肿瘤组织的保存方法及保存试剂 |
| EP3675876A4 (en) | 2017-09-01 | 2021-06-02 | GPB Scientific, Inc. | METHOD FOR PRODUCING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDICS |
| WO2019070658A1 (en) * | 2017-10-03 | 2019-04-11 | The Regents Of The University Of California | APPARATUS AND METHOD FOR DETERMINING SPATIAL PROBABILITY OF CANCER IN PROSTATE |
| US11458474B2 (en) | 2018-01-19 | 2022-10-04 | International Business Machines Corporation | Microfluidic chips with one or more vias |
| US10946380B2 (en) | 2018-01-19 | 2021-03-16 | International Business Machines Corporation | Microfluidic chips for particle purification and fractionation |
| US20190226953A1 (en) | 2018-01-19 | 2019-07-25 | International Business Machines Corporation | Microscale and mesoscale condenser devices |
| JP7170254B2 (ja) * | 2018-02-14 | 2022-11-14 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| JP7109719B2 (ja) | 2018-02-14 | 2022-08-01 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| JP7158671B2 (ja) | 2018-02-14 | 2022-10-24 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| WO2020056162A1 (en) * | 2018-09-12 | 2020-03-19 | Oregon Health & Science University | Detecting and/or subtyping circulating hybrid cells that correlate with stage and survival |
| US12385908B2 (en) * | 2018-12-27 | 2025-08-12 | The General Hospital Corporation | Size-based particle separation and concentration using particle size amplification |
| US11614440B2 (en) | 2019-01-24 | 2023-03-28 | Sumitomo Rubber Industries, Ltd. | Specific cell fractionating and capturing methods |
| EP3999081A1 (en) | 2019-07-18 | 2022-05-25 | GPB Scientific, Inc. | Ordered processing of blood products to produce therapeutically active cells |
| US20230028754A1 (en) | 2019-12-28 | 2023-01-26 | Gpb Scientific, Inc. | Microfluidic cartridges for processing particles and cells |
| CN111537422B (zh) * | 2020-06-10 | 2022-09-23 | 兰州大学 | 表征及调控包晶合金定向凝固时糊状区内渗透率的方法 |
| CN111676289A (zh) * | 2020-06-19 | 2020-09-18 | 安徽微分基因科技有限公司 | 一种egfr基因19号外显子e746-a750突变基因的检测方法 |
| WO2021263038A1 (en) * | 2020-06-25 | 2021-12-30 | Arrive PTE Ltd. | System and methods for characterizing cells and microenvironments |
| WO2022070841A1 (ja) * | 2020-09-29 | 2022-04-07 | Nok株式会社 | 白血球捕捉デバイス |
| CN118922704A (zh) * | 2022-03-28 | 2024-11-08 | 国立大学法人茨城大学 | 白血球捕捉设备 |
| CN116286268B (zh) * | 2023-03-21 | 2025-07-08 | 中国科学院上海微系统与信息技术研究所 | 一种基于微流控技术的外泌体分离装置及其方法 |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3906929A (en) * | 1973-11-23 | 1975-09-23 | Lynn Lawrence Augspurger | Processes for reproduction of cellular bodies |
| US4508625A (en) * | 1982-10-18 | 1985-04-02 | Graham Marshall D | Magnetic separation using chelated magnetic ions |
| US4675286A (en) * | 1985-01-28 | 1987-06-23 | Aspen Diagnostics, Inc. | Fetal cell separation and testing |
| US4999283A (en) * | 1986-01-10 | 1991-03-12 | University Of Kentucky Research Foundation | Method for x and y spermatozoa separation |
| US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| US5641628A (en) | 1989-11-13 | 1997-06-24 | Children's Medical Center Corporation | Non-invasive method for isolation and detection of fetal DNA |
| US5153117A (en) * | 1990-03-27 | 1992-10-06 | Genetype A.G. | Fetal cell recovery method |
| US5726026A (en) * | 1992-05-01 | 1998-03-10 | Trustees Of The University Of Pennsylvania | Mesoscale sample preparation device and systems for determination and processing of analytes |
| US5304487A (en) * | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
| US5637469A (en) * | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
| US5296375A (en) * | 1992-05-01 | 1994-03-22 | Trustees Of The University Of Pennsylvania | Mesoscale sperm handling devices |
| US5629147A (en) * | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| US5457024A (en) * | 1993-01-22 | 1995-10-10 | Aprogenex, Inc. | Isolation of fetal erythrocytes |
| US5427663A (en) | 1993-06-08 | 1995-06-27 | British Technology Group Usa Inc. | Microlithographic array for macromolecule and cell fractionation |
| EP0657811B1 (en) | 1993-12-09 | 1998-09-02 | STMicroelectronics S.r.l. | Integrated circuitry for checking the utilization rate of redundancy memory elements in a semiconductor memory device |
| US5432054A (en) * | 1994-01-31 | 1995-07-11 | Applied Imaging | Method for separating rare cells from a population of cells |
| US20020042079A1 (en) * | 1994-02-01 | 2002-04-11 | Sanford M. Simon | Methods and agents for measuring and controlling multidrug resistance |
| US5750339A (en) * | 1994-11-30 | 1998-05-12 | Thomas Jefferson University | Methods for identifying fetal cells |
| US5648220A (en) * | 1995-02-14 | 1997-07-15 | New England Medical Center Hospitals, Inc. | Methods for labeling intracytoplasmic molecules |
| US5715946A (en) * | 1995-06-07 | 1998-02-10 | Reichenbach; Steven H. | Method and apparatus for sorting particles suspended in a fluid |
| DE19681033D2 (de) * | 1995-11-16 | 1999-03-18 | Michael W Dahm | Verfahren zur Quantifizierung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
| US5972721A (en) * | 1996-03-14 | 1999-10-26 | The United States Of America As Represented By The Secretary Of The Air Force | Immunomagnetic assay system for clinical diagnosis and other purposes |
| US5891651A (en) * | 1996-03-29 | 1999-04-06 | Mayo Foundation For Medical Education And Research | Methods of recovering colorectal epithelial cells or fragments thereof from stool |
| US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
| EP0929658A4 (en) * | 1996-08-26 | 2005-11-02 | Univ Princeton | REVERSIBLE SEALABLE DEVICE FOR SORTING MICROSTRUCTURES |
| JP2002503334A (ja) * | 1996-09-04 | 2002-01-29 | テクニカル ユニバーシティ オブ デンマーク | 粒子の分離と分析用のマイクロフローシステム |
| GB9704876D0 (en) * | 1997-03-08 | 1997-04-23 | Univ Dundee | Diagnostic methods |
| US6066449A (en) * | 1997-04-15 | 2000-05-23 | The Trustees Of Columbia University In The City Of New York | Method of detecting metastatic thyroid cancer |
| US6156273A (en) * | 1997-05-27 | 2000-12-05 | Purdue Research Corporation | Separation columns and methods for manufacturing the improved separation columns |
| US6368871B1 (en) * | 1997-08-13 | 2002-04-09 | Cepheid | Non-planar microstructures for manipulation of fluid samples |
| US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
| SE521415C2 (sv) * | 1998-02-17 | 2003-10-28 | Hans Goeran Evald Martin | Metod för att framställa en gassensortillhörig detektor, samt en detektor framställd enligt metoden |
| US6537505B1 (en) * | 1998-02-20 | 2003-03-25 | Bio Dot, Inc. | Reagent dispensing valve |
| US6036857A (en) * | 1998-02-20 | 2000-03-14 | Florida State University Research Foundation, Inc. | Apparatus for continuous magnetic separation of components from a mixture |
| US6027623A (en) * | 1998-04-22 | 2000-02-22 | Toyo Technologies, Inc. | Device and method for electrophoretic fraction |
| US6200765B1 (en) * | 1998-05-04 | 2001-03-13 | Pacific Northwest Cancer Foundation | Non-invasive methods to detect prostate cancer |
| EP1190229B1 (en) * | 1998-05-22 | 2011-10-26 | California Institute Of Technology | Microfabricated cell sorter |
| AU4546899A (en) * | 1998-06-05 | 1999-12-20 | Sarnoff Corporation | Apparatus for separating molecules |
| US6576478B1 (en) * | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
| CA2335649A1 (en) | 1998-07-20 | 2000-01-27 | Variagenics, Inc. | Gene sequence variances with utility in determining the treatment of disease |
| US6337472B1 (en) * | 1998-10-19 | 2002-01-08 | The University Of Texas System Board Of Regents | Light imaging microscope having spatially resolved images |
| ATE556149T1 (de) * | 1999-02-23 | 2012-05-15 | Caliper Life Sciences Inc | Manipulation von mikropartikeln in mikrofluidischen systemen |
| JP3863373B2 (ja) * | 1999-03-02 | 2006-12-27 | クオリジエン・インコーポレイテツド | 生物学的流体の分離のための装置を用いる方法 |
| US6942978B1 (en) * | 1999-03-03 | 2005-09-13 | The Board Of Trustees Of The University Of Arkansas | Transmembrane serine protease overexpressed in ovarian carcinoma and uses thereof |
| US6858439B1 (en) * | 1999-03-15 | 2005-02-22 | Aviva Biosciences | Compositions and methods for separation of moieties on chips |
| US6368562B1 (en) * | 1999-04-16 | 2002-04-09 | Orchid Biosciences, Inc. | Liquid transportation system for microfluidic device |
| US6589791B1 (en) * | 1999-05-20 | 2003-07-08 | Cartesian Technologies, Inc. | State-variable control system |
| US6395232B1 (en) * | 1999-07-09 | 2002-05-28 | Orchid Biosciences, Inc. | Fluid delivery system for a microfluidic device using a pressure pulse |
| US6623945B1 (en) * | 1999-09-16 | 2003-09-23 | Motorola, Inc. | System and method for microwave cell lysing of small samples |
| US6692952B1 (en) | 1999-11-10 | 2004-02-17 | Massachusetts Institute Of Technology | Cell analysis and sorting apparatus for manipulation of cells |
| US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
| US20030170631A1 (en) * | 2000-04-03 | 2003-09-11 | Corixa Corporation | Methods, compositions and kits for the detection and monitoring of breast cancer |
| SE0001790D0 (sv) * | 2000-05-12 | 2000-05-12 | Aamic Ab | Hydrophobic barrier |
| AU8843701A (en) * | 2000-09-09 | 2002-03-22 | Univ New York State Res Found | Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof |
| US6689615B1 (en) * | 2000-10-04 | 2004-02-10 | James Murto | Methods and devices for processing blood samples |
| CA2424941A1 (en) * | 2000-10-10 | 2002-04-18 | Aviva Biosciences Corporation | An integrated biochip system for sample preparation and analysis |
| US6521188B1 (en) * | 2000-11-22 | 2003-02-18 | Industrial Technology Research Institute | Microfluidic actuator |
| US6778724B2 (en) * | 2000-11-28 | 2004-08-17 | The Regents Of The University Of California | Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices |
| FR2817967B1 (fr) * | 2000-12-08 | 2003-02-28 | Diagast | Procede de magnetisation de marqueurs chimiques ou biologiques |
| US6453928B1 (en) * | 2001-01-08 | 2002-09-24 | Nanolab Ltd. | Apparatus, and method for propelling fluids |
| US6939670B2 (en) * | 2001-03-12 | 2005-09-06 | Monogen, Inc. | Cell-based detection and differentiation of lung cancer |
| US7323140B2 (en) * | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
| EP1377821A2 (en) * | 2001-04-03 | 2004-01-07 | Micronics, Inc. | Pneumatic valve interface for use in microfluidic structures |
| FR2824144B1 (fr) * | 2001-04-30 | 2004-09-17 | Metagenex S A R L | Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel |
| US6743636B2 (en) * | 2001-05-24 | 2004-06-01 | Industrial Technology Research Institute | Microfluid driving device |
| US20050026167A1 (en) * | 2001-06-11 | 2005-02-03 | Mark Birch-Machin | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| JP3695431B2 (ja) * | 2001-08-03 | 2005-09-14 | 日本電気株式会社 | 分離装置および分離装置の製造方法 |
| KR20040032884A (ko) * | 2001-08-03 | 2004-04-17 | 닛본 덴끼 가부시끼가이샤 | 분리 장치 및 분리 장치의 제조 방법 |
| US7863012B2 (en) * | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
| CA2458704A1 (en) * | 2001-09-04 | 2003-03-13 | Iq Corporation B.V. | Determination and quantification of red blood cell populations in samples |
| DE10143776A1 (de) * | 2001-09-06 | 2003-04-03 | Adnagen Ag | Verfahren und Kit zur Diagnostik oder Behandlungskontrolle von Brustkrebs |
| JP4336198B2 (ja) * | 2001-09-06 | 2009-09-30 | アトナーゲン アクチエンゲゼルシャフト | 細胞の選択、および／または定性および／または定量検出のための方法および診断キット |
| US6783647B2 (en) * | 2001-10-19 | 2004-08-31 | Ut-Battelle, Llc | Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate |
| US20050118591A1 (en) * | 2001-11-22 | 2005-06-02 | Adnagen Ag | Diagnosis kit, dna chip, and methods for diagnosing or supervising the treatment of testicular cancer |
| AU2002347468A1 (en) * | 2001-11-30 | 2003-06-10 | Pfizer Products Inc. | Methods for detecting cells with numerical chromosomal abnormalities |
| AU2003285849A1 (en) * | 2002-03-20 | 2004-03-29 | Advanced Sensor Technologies, Inc. | Personal monitor to detect exposure to toxic agents |
| WO2003085379A2 (en) * | 2002-04-01 | 2003-10-16 | Fluidigm Corporation | Microfluidic particle-analysis systems |
| SE0201738D0 (sv) * | 2002-06-07 | 2002-06-07 | Aamic Ab | Micro-fluid structures |
| US20040101444A1 (en) * | 2002-07-15 | 2004-05-27 | Xeotron Corporation | Apparatus and method for fluid delivery to a hybridization station |
| US20060008807A1 (en) * | 2002-08-23 | 2006-01-12 | O'hara Shawn M | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
| US7455770B2 (en) * | 2002-09-09 | 2008-11-25 | Cytonome, Inc. | Implementation of microfluidic components in a microfluidic system |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| EP1585583B1 (en) | 2002-10-23 | 2010-04-07 | The Trustees of Princeton University | Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields |
| WO2004113877A1 (en) | 2003-06-13 | 2004-12-29 | The General Hospital Corporation | Microfluidic systems for size based removal of red blood cells and platelets from blood |
| AU2004266572A1 (en) | 2003-08-01 | 2005-03-03 | Wyeth Holdings Corporation | Use of combination of an epidermal growth factor receptor kinase inhibitor and cytotoxic agents for treatment and inhibition of cancer |
| US20050069528A1 (en) * | 2003-08-21 | 2005-03-31 | Genzyme Corporation | Mammalian endothelial cell model systems |
| US7745221B2 (en) * | 2003-08-28 | 2010-06-29 | Celula, Inc. | Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network |
| WO2005043120A2 (en) * | 2003-10-29 | 2005-05-12 | Mec Dynamics Corp. | Micro mechanical methods and systems for performing assays |
| US7939249B2 (en) * | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
| US20050181353A1 (en) * | 2004-02-17 | 2005-08-18 | Rao Galla C. | Stabilization of cells and biological specimens for analysis |
| AU2005218622A1 (en) | 2004-03-03 | 2005-09-15 | Living Microsystems | Magnetic device for isolation of cells and biomolecules in a microfluidic environment |
| US20060121624A1 (en) * | 2004-03-03 | 2006-06-08 | Huang Lotien R | Methods and systems for fluid delivery |
| WO2005084380A2 (en) | 2004-03-03 | 2005-09-15 | The General Hospital Corporation | System for delivering a diluted solution |
| US7390388B2 (en) * | 2004-03-25 | 2008-06-24 | Hewlett-Packard Development Company, L.P. | Method of sorting cells on a biodevice |
| EP3611273A1 (en) | 2004-03-31 | 2020-02-19 | The General Hospital Corporation | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments |
| WO2005108963A1 (en) * | 2004-05-06 | 2005-11-17 | Nanyang Technological University | Microfluidic cell sorter system |
| DE102004047953A1 (de) * | 2004-10-01 | 2006-04-20 | Rudolf Rigler | Selektion von Partikeln im laminaren Fluss |
| US20060246575A1 (en) * | 2005-01-13 | 2006-11-02 | Micronics, Inc. | Microfluidic rare cell detection device |
| US8158410B2 (en) * | 2005-01-18 | 2012-04-17 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| US20070026413A1 (en) * | 2005-07-29 | 2007-02-01 | Mehmet Toner | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070026415A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070196820A1 (en) * | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US20070026418A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070026417A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070026414A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070026419A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070059680A1 (en) * | 2005-09-15 | 2007-03-15 | Ravi Kapur | System for cell enrichment |
| US20070026416A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US8921102B2 (en) * | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20070059718A1 (en) * | 2005-09-15 | 2007-03-15 | Mehmet Toner | Systems and methods for enrichment of analytes |
| US20070059716A1 (en) * | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
| US20070059683A1 (en) * | 2005-09-15 | 2007-03-15 | Tom Barber | Veterinary diagnostic system |
| EP1931800A4 (en) * | 2005-09-15 | 2011-06-15 | Artemis Health Inc | SYSTEMS AND METHOD FOR ENRICHING ANALYTES |
| US20070059781A1 (en) * | 2005-09-15 | 2007-03-15 | Ravi Kapur | System for size based separation and analysis |
| US20070059719A1 (en) * | 2005-09-15 | 2007-03-15 | Michael Grisham | Business methods for prenatal Diagnosis |
| US20070059774A1 (en) * | 2005-09-15 | 2007-03-15 | Michael Grisham | Kits for Prenatal Testing |
-
2006
- 2006-04-05 EP EP06749394A patent/EP1874920A4/en not_active Withdrawn
- 2006-04-05 EP EP12180052.8A patent/EP2594631A1/en not_active Withdrawn
- 2006-04-05 WO PCT/US2006/012778 patent/WO2006108087A2/en not_active Ceased
- 2006-04-05 JP JP2008505508A patent/JP2008538282A/ja active Pending
- 2006-04-05 GB GB0612649A patent/GB2427468B/en not_active Expired - Lifetime
- 2006-06-08 US US11/449,161 patent/US20070099207A1/en not_active Abandoned
-
2009
- 2009-07-09 US US12/500,541 patent/US20110306043A1/en not_active Abandoned
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