JP2008538109A5 - - Google Patents
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- Publication number
- JP2008538109A5 JP2008538109A5 JP2008502895A JP2008502895A JP2008538109A5 JP 2008538109 A5 JP2008538109 A5 JP 2008538109A5 JP 2008502895 A JP2008502895 A JP 2008502895A JP 2008502895 A JP2008502895 A JP 2008502895A JP 2008538109 A5 JP2008538109 A5 JP 2008538109A5
- Authority
- JP
- Japan
- Prior art keywords
- fluoro
- alkyl
- phenyl
- methanesulfonylamino
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2005-0022986 | 2005-03-19 | ||
| KR20050022986 | 2005-03-19 | ||
| US66326905P | 2005-03-21 | 2005-03-21 | |
| US60/663,269 | 2005-03-21 | ||
| PCT/KR2006/000929 WO2006101318A1 (en) | 2005-03-19 | 2006-03-15 | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008538109A JP2008538109A (ja) | 2008-10-09 |
| JP2008538109A5 true JP2008538109A5 (https=) | 2009-04-09 |
| JP5159604B2 JP5159604B2 (ja) | 2013-03-06 |
Family
ID=37023953
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008502895A Expired - Fee Related JP5159604B2 (ja) | 2005-03-19 | 2006-03-15 | バニロイド受容体拮抗薬としての新規な化合物、その異性体又はその薬剤学的に許容される塩、及びこれを含む医薬組成物 |
| JP2008502896A Expired - Fee Related JP5064374B2 (ja) | 2005-03-19 | 2006-03-17 | バニロイド受容体拮抗薬としての新規な化合物、その異性体またはその薬剤学的に許容される塩、及びこれを含む医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008502896A Expired - Fee Related JP5064374B2 (ja) | 2005-03-19 | 2006-03-17 | バニロイド受容体拮抗薬としての新規な化合物、その異性体またはその薬剤学的に許容される塩、及びこれを含む医薬組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7763657B2 (https=) |
| EP (2) | EP1861357B1 (https=) |
| JP (2) | JP5159604B2 (https=) |
| KR (2) | KR101304981B1 (https=) |
| AR (2) | AR053561A1 (https=) |
| AU (2) | AU2006225496A1 (https=) |
| BR (2) | BRPI0608714A2 (https=) |
| CA (2) | CA2601871A1 (https=) |
| EA (2) | EA200702020A1 (https=) |
| IL (2) | IL185891A0 (https=) |
| MX (2) | MX2007011466A (https=) |
| NO (2) | NO20075353L (https=) |
| TW (2) | TW200716523A (https=) |
| WO (2) | WO2006101318A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101304981B1 (ko) * | 2005-03-19 | 2013-09-06 | (주)아모레퍼시픽 | 바닐로이드 수용체 길항물질로서의 신규 화합물, 이의이성체 또는 이의 약학적으로 허용가능한 염, 및 이를함유하는 약학 조성물 |
| PL2054411T3 (pl) | 2006-07-27 | 2015-02-27 | Amorepacific Corp | Nowe związki, ich izomery lub ich farmaceutycznie dopuszczalne sole jako antagoniści receptora waniloidowego oraz zawierające je kompozycje farmaceutyczne |
| DE102007017884A1 (de) | 2007-04-13 | 2008-10-16 | Grünethal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
| US20110160279A1 (en) * | 2007-08-13 | 2011-06-30 | Board Of Trustees Of Southern Illinois University | METHODS FOR TREATMENT AND PREVENTION OF OTOTOXICITY BY siRNA |
| US8557872B2 (en) | 2008-01-28 | 2013-10-15 | Amorepacific Corporation | Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| WO2009136625A1 (ja) * | 2008-05-07 | 2009-11-12 | 大日本住友製薬株式会社 | 環状アミン－１－カルボン酸エステル誘導体およびそれを含有する医薬組成物 |
| US8691855B2 (en) | 2008-07-02 | 2014-04-08 | Amorepacific Corporation | Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist and pharmaceutical compositions containing the same |
| CN103429242A (zh) * | 2010-11-03 | 2013-12-04 | 夏威夷大学 | 用于预防和治疗心脏肥大的方法和组合物 |
| AR085509A1 (es) | 2011-03-09 | 2013-10-09 | Bayer Cropscience Ag | Indol- y bencimidazolcarboxamidas como insecticidas y acaricidas |
| ES2643403T3 (es) | 2011-12-28 | 2017-11-22 | Global Blood Therapeutics, Inc. | Compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular |
| HK1203412A1 (en) | 2011-12-28 | 2015-10-30 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| HK1214587A1 (en) * | 2012-12-28 | 2016-07-29 | Nippon Zoki Pharmaceutical Co., Ltd. | Cinnamamide derivative |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| CN105073728A (zh) | 2013-03-15 | 2015-11-18 | 全球血液疗法股份有限公司 | 化合物及其用于调节血红蛋白的用途 |
| WO2014150258A1 (en) | 2013-03-15 | 2014-09-25 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| MX379235B (es) | 2013-03-15 | 2025-03-11 | Global Blood Therapeutics Inc | Compuestos y sus usos para modular la hemoglobina. |
| CN114181195A (zh) | 2014-02-07 | 2022-03-15 | 全球血液疗法股份有限公司 | 一种化合物的结晶多晶型物 |
| SG11201804647TA (en) | 2015-12-04 | 2018-06-28 | Global Blood Therapeutics Inc | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| US11014884B2 (en) | 2018-10-01 | 2021-05-25 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6087254A (ja) * | 1983-10-19 | 1985-05-16 | Japan Carlit Co Ltd:The | 新規尿素化合物及びそれを含有する除草剤 |
| HK1042472B (zh) * | 1999-02-22 | 2005-12-09 | Medifron Dbt Co., Ltd. | 作爲有效的香草类受体激动剂和镇痛药的含有树脂毒素药效基团的香草类类似物，其组合物以及应用 |
| ATE328868T1 (de) | 2000-08-21 | 2006-06-15 | Pacific Corp | Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten |
| AU2001280229B2 (en) | 2000-08-21 | 2006-12-07 | Pacific Corporation | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
| GB0105895D0 (en) * | 2001-03-09 | 2001-04-25 | Smithkline Beecham Plc | Novel compounds |
| MXPA04005427A (es) | 2001-12-10 | 2005-04-19 | Amgen Inc | Ligandos de receptor vainilloide y su uso en tratamientos. |
| BR0309940A (pt) * | 2002-05-08 | 2005-02-09 | Bayer Healthcare Ag | Derivados de hidróxi-tetraidro-naftaleniluréia |
| AU2003251828A1 (en) * | 2002-07-12 | 2004-02-02 | Janssen Pharmaceutica N.V. | Naphthol, quinoline and isoquinoline-derivatives as modulators of vanilloid vr1 receptor |
| KR100707123B1 (ko) * | 2003-07-02 | 2007-04-16 | 그뤼넨탈 게엠베하 | 바닐로이드 수용체의 길항제로서 강력한 진통효과를나타내는 4-(메틸설포닐아미노)페닐 동족체 및 이를함유하는 약학적 조성물 |
| KR101042490B1 (ko) * | 2004-07-15 | 2011-06-16 | 니뽄 다바코 산교 가부시키가이샤 | 축합 벤즈아미드 화합물 및 바닐로이드 수용체 1형(ｖｒ1)활성 저해제 |
| ITMI20042042A1 (it) * | 2004-10-26 | 2005-01-26 | Pharmeste Srl | Derivati solfonammidici antagonisti del recettore dei vanilloidi trpv1 |
| ES2331153T3 (es) * | 2005-03-10 | 2009-12-22 | Pfizer Inc. | Compuestos de n-sulfonilaminofeniletil-2-fenoxiacetamida sustituidos. |
| KR101304981B1 (ko) | 2005-03-19 | 2013-09-06 | (주)아모레퍼시픽 | 바닐로이드 수용체 길항물질로서의 신규 화합물, 이의이성체 또는 이의 약학적으로 허용가능한 염, 및 이를함유하는 약학 조성물 |
-
2006
- 2006-03-15 KR KR1020077024002A patent/KR101304981B1/ko not_active Expired - Fee Related
- 2006-03-15 JP JP2008502895A patent/JP5159604B2/ja not_active Expired - Fee Related
- 2006-03-15 BR BRPI0608714-0A patent/BRPI0608714A2/pt not_active Application Discontinuation
- 2006-03-15 US US11/909,136 patent/US7763657B2/en active Active
- 2006-03-15 EA EA200702020A patent/EA200702020A1/ru unknown
- 2006-03-15 EP EP06716379.0A patent/EP1861357B1/en not_active Expired - Lifetime
- 2006-03-15 MX MX2007011466A patent/MX2007011466A/es not_active Application Discontinuation
- 2006-03-15 AU AU2006225496A patent/AU2006225496A1/en not_active Abandoned
- 2006-03-15 WO PCT/KR2006/000929 patent/WO2006101318A1/en not_active Ceased
- 2006-03-15 CA CA002601871A patent/CA2601871A1/en not_active Abandoned
- 2006-03-17 TW TW095109337A patent/TW200716523A/zh unknown
- 2006-03-17 CA CA002601873A patent/CA2601873A1/en not_active Abandoned
- 2006-03-17 WO PCT/KR2006/000988 patent/WO2006101321A1/en not_active Ceased
- 2006-03-17 US US11/909,144 patent/US7960584B2/en active Active
- 2006-03-17 EP EP06716438A patent/EP1861358A4/en not_active Withdrawn
- 2006-03-17 AR ARP060101059A patent/AR053561A1/es unknown
- 2006-03-17 KR KR1020077024004A patent/KR101304979B1/ko not_active Expired - Fee Related
- 2006-03-17 TW TW095109137A patent/TW200716522A/zh unknown
- 2006-03-17 MX MX2007011205A patent/MX2007011205A/es not_active Application Discontinuation
- 2006-03-17 EA EA200702021A patent/EA200702021A1/ru unknown
- 2006-03-17 BR BRPI0608624-1A patent/BRPI0608624A2/pt not_active Application Discontinuation
- 2006-03-17 AU AU2006225434A patent/AU2006225434A1/en not_active Abandoned
- 2006-03-17 JP JP2008502896A patent/JP5064374B2/ja not_active Expired - Fee Related
- 2006-03-17 AR ARP060101058A patent/AR056943A1/es unknown
-
2007
- 2007-09-11 IL IL185891A patent/IL185891A0/en unknown
- 2007-09-11 IL IL185892A patent/IL185892A0/en unknown
- 2007-10-18 NO NO20075353A patent/NO20075353L/no not_active Application Discontinuation
- 2007-10-18 NO NO20075354A patent/NO20075354L/no not_active Application Discontinuation
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