EA200702021A1 - Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции - Google Patents

Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции

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EA200702021A1
EA200702021A1 EA200702021A EA200702021A EA200702021A1 EA 200702021 A1 EA200702021 A1 EA 200702021A1 EA 200702021 A EA200702021 A EA 200702021A EA 200702021 A EA200702021 A EA 200702021A EA 200702021 A1 EA200702021 A1 EA 200702021A1
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Prior art keywords
antagonists
isomers
pharmaceutically acceptable
acceptable salts
new compounds
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EA200702021A
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English (en)
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Янг-Гер Сух
Хее-Доо Ким
Хиеунг-Геун Парк
Ух Таек Ох
Йонг-Сил Ли
Сеол Рин Парк
Чонг Хион Риу
Янг-Хо Парк
Сонг Сеок Шин
Сун-Янг Ким
Дзин Кван Ким
Йеон Су Дзеонг
Ки-Вха Ли
Дзин Киу Чои
Киунг Мин Лим
Хиун Дзу Кох
Дзоо Хиун Мох
Сунг-Ил Ким
Дзоо Хо Бае
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Эморпасифик Корпорейшн
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Publication of EA200702021A1 publication Critical patent/EA200702021A1/ru

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Abstract

Настоящее изобретение касается новых соединений, их изомеров или фармацевтически приемлемых солей в качестве антагонистов ваниллоидного рецептора (ваниллоидного рецептора 1; VR1; TRPV1) и содержащей их фармацевтической композиции. Настоящее изобретение касается фармацевтической композиции для профилактики или лечения такого заболевания, как боль, мигрень, артралгия, невралгия, невропатия, повреждение нервов, кожное нарушение, гиперчувствительность мочевого пузыря, синдром раздраженного кишечника, сильная потребность в калоиспускании, респираторное нарушение, раздражение кожи, глаз или слизистой оболочки, язва желудка-двенадцатиперстной кишки, воспалительные заболевания, ушное заболевание, заболевание сердца.
EA200702021A 2005-03-19 2006-03-17 Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции EA200702021A1 (ru)

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KR20050022986 2005-03-19
US66326905P 2005-03-21 2005-03-21
PCT/KR2006/000988 WO2006101321A1 (en) 2005-03-19 2006-03-17 Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same

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EA200702021A1 true EA200702021A1 (ru) 2008-02-28

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EA200702020A EA200702020A1 (ru) 2005-03-19 2006-03-15 Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции
EA200702021A EA200702021A1 (ru) 2005-03-19 2006-03-17 Новые соединения, их изомеры или фармацевтически приемлемые соли в качестве антагонистов ваниллоидных рецепторов и содержащие их фармацевтические композиции

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US (2) US7763657B2 (ru)
EP (2) EP1861357B1 (ru)
JP (2) JP5159604B2 (ru)
KR (2) KR101304981B1 (ru)
AR (2) AR056943A1 (ru)
AU (2) AU2006225496A1 (ru)
BR (2) BRPI0608714A2 (ru)
CA (2) CA2601871A1 (ru)
EA (2) EA200702020A1 (ru)
IL (2) IL185891A0 (ru)
MX (2) MX2007011466A (ru)
NO (2) NO20075353L (ru)
TW (2) TW200716523A (ru)
WO (2) WO2006101318A1 (ru)

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CA2601871A1 (en) * 2005-03-19 2006-09-28 Amorepacific Corporation Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
AR063211A1 (es) 2006-07-27 2009-01-14 Amorepacific Corp Derivados de 3-(piridin-3-il)acrilamida y 3-(piridin-3-il)propionamida, un metodo para su preparacion, una composicion farmaceutica que los comprende y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades asociadas con el receptor vaniloide.
DE102007017884A1 (de) * 2007-04-13 2008-10-16 Grünethal GmbH Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
US20110160279A1 (en) * 2007-08-13 2011-06-30 Board Of Trustees Of Southern Illinois University METHODS FOR TREATMENT AND PREVENTION OF OTOTOXICITY BY siRNA
US8557872B2 (en) * 2008-01-28 2013-10-15 Amorepacific Corporation Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
CN102089277B (zh) * 2008-05-07 2014-02-12 大日本住友制药株式会社 环状胺-1-甲酸酯衍生物及含有其的药物组合物
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