JP2008526939A5 - - Google Patents
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- JP2008526939A5 JP2008526939A5 JP2007550844A JP2007550844A JP2008526939A5 JP 2008526939 A5 JP2008526939 A5 JP 2008526939A5 JP 2007550844 A JP2007550844 A JP 2007550844A JP 2007550844 A JP2007550844 A JP 2007550844A JP 2008526939 A5 JP2008526939 A5 JP 2008526939A5
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- tetanus toxoid
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- 髄膜炎菌により引き起こされる疾患に対してヒト患者を免疫するための方法における使用のための組成物であって、該組成物は、
(a)(i)血清群A 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;(b)(i)血清群C 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;(c)(i)血清群W135 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;および(d)(i)血清群Y 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;のうちの少なくとも2つを含み、該方法は該組成物を該ヒト患者に投与する工程を包含し、該患者は、(a)破傷風トキソイド;および/または(b)(i)髄膜炎菌以外の生物の莢膜糖と(ii)破傷風トキソイドとの結合体で予備免疫されている、組成物。 - 髄膜炎菌により引き起こされる疾患を予防するための医薬の製造における、
(a)(i)血清群A 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;(b)(i)血清群C 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;(c)(i)血清群W135 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;および(d)(i)血清群Y 髄膜炎菌の莢膜糖と(ii)破傷風トキソイドとの結合体;のうちの少なくとも2つの使用であって、
該患者は、(a)破傷風トキソイド;および/または(b)(i)髄膜炎菌以外の生物の莢膜糖と(ii)破傷風トキソイドとの結合体で予備免疫されている、使用。 - 請求項1に記載の組成物であって、前記組成物は、(a)、(b)、(c)および(d)の4つすべてを含む、組成物。
- 請求項2に記載の使用であって、前記使用が(a)、(b)、(c)および(d)の4つすべての使用である、使用。
- 請求項3に記載の組成物または請求項4に記載の使用であって、前記結合体が、(糖の質量として測定して)1:1:1:1の比を生じるように混合される、組成物または使用。
- 請求項1〜5のうちのいずれか1項に記載の組成物または使用であって、1用量当たりの各髄膜炎菌抗原は、血清群1つ当たり(糖に関して測定すると)2μg〜10μgである、組成物または使用。
- 請求項1〜6のうちのいずれか1項に記載の組成物または使用であって、前記患者は、破傷風トキソイドを含むワクチンで予備免疫されている、組成物または使用。
- 請求項1〜7のうちのいずれか1項に記載の組成物または使用であって、前記患者は、Hib結合体を含むワクチンで予備免疫されている、組成物または使用。
- 請求項1〜8のうちのいずれか1項に記載の組成物または使用であって、前記患者は、少なくとも1つの肺炎球菌結合体を含むワクチンで予備免疫されている、組成物または使用。
- 請求項1〜9のうちのいずれか1項に記載の組成物または使用であって、前記患者は、前記方法または使用の少なくとも6ヶ月前に予備免疫されている、組成物または使用。
- 請求項10に記載の組成物または使用であって、前記患者は、前記方法または使用の少なくとも8年間前に予備免疫されている、組成物または使用。
- 請求項1〜11のうちのいずれか1項に記載の組成物または使用であって、前記予備免疫は、前記患者の出生から1年間以内に行われている、組成物または使用。
- 請求項1〜12のうちのいずれか1項に記載の組成物または使用であって、前記髄膜炎菌結合体(a)〜(d)中の糖は、脱重合されており、したがって髄膜炎菌において見出されるネイティブ莢膜糖よりも短い、組成物または使用。
- 請求項1〜13のうちのいずれか1項に記載の組成物または使用であって、前記髄膜炎菌結合体は、破傷風トキソイドキャリアおよびアジピン酸リンカーを含む、組成物または使用。
- 請求項14に記載の組成物または使用であって、60μg以下の破傷風トキソイドキャリアを含む、組成物または使用。
- 請求項1〜15のうちのいずれか1項に記載の組成物または使用であって、前記組成物または医薬は、肺炎連鎖球菌由来の結合体化莢膜糖をさらに含む、組成物または使用。
- 請求項1〜16のうちのいずれか1項に記載の組成物または使用であって、前記組成物または医薬は、B型インフルエンザ菌由来の結合体化莢膜糖をさらに含む、組成物または使用。
- 請求項1〜17のうちのいずれか1項に記載の組成物または使用であって、前記組成物または医薬は、血清群Bの髄膜炎菌由来のタンパク質抗原をさらに含む、組成物または使用。
- 請求項1〜18のうちのいずれか1項に記載の組成物または使用であって、前記組成物または医薬は、水酸化アルミニウムアジュバントおよび/またはリン酸アルミニウムアジュバントを含む、組成物または使用。
- 請求項1〜19のうちのいずれか1項に記載の組成物または使用であって、前記髄膜炎菌により引き起こされる疾患は、髄膜炎菌性髄膜炎である、組成物または使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0500787.7 | 2005-01-14 | ||
GBGB0500787.7A GB0500787D0 (en) | 2005-01-14 | 2005-01-14 | Integration of meningococcal conjugate vaccination |
PCT/GB2006/000120 WO2006075170A1 (en) | 2005-01-14 | 2006-01-13 | Meningococcal conjugate vaccination |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012128887A Division JP2012162580A (ja) | 2005-01-14 | 2012-06-06 | 髄膜炎菌結合体ワクチン接種 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2008526939A JP2008526939A (ja) | 2008-07-24 |
JP2008526939A5 true JP2008526939A5 (ja) | 2009-01-08 |
JP5687405B2 JP5687405B2 (ja) | 2015-03-18 |
Family
ID=34224621
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007550844A Active JP5687405B2 (ja) | 2005-01-14 | 2006-01-13 | 髄膜炎菌結合体ワクチン接種 |
JP2012128887A Withdrawn JP2012162580A (ja) | 2005-01-14 | 2012-06-06 | 髄膜炎菌結合体ワクチン接種 |
JP2014104349A Withdrawn JP2014144984A (ja) | 2005-01-14 | 2014-05-20 | 髄膜炎菌結合体ワクチン接種 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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JP2012128887A Withdrawn JP2012162580A (ja) | 2005-01-14 | 2012-06-06 | 髄膜炎菌結合体ワクチン接種 |
JP2014104349A Withdrawn JP2014144984A (ja) | 2005-01-14 | 2014-05-20 | 髄膜炎菌結合体ワクチン接種 |
Country Status (20)
Country | Link |
---|---|
US (1) | US8529908B2 (ja) |
EP (2) | EP2193810A1 (ja) |
JP (3) | JP5687405B2 (ja) |
CN (2) | CN101163508A (ja) |
AT (1) | ATE463261T1 (ja) |
AU (1) | AU2006205656B2 (ja) |
BR (1) | BRPI0606523A2 (ja) |
CA (1) | CA2595128C (ja) |
CY (1) | CY1110140T1 (ja) |
DE (1) | DE602006013406D1 (ja) |
DK (1) | DK1835939T3 (ja) |
ES (1) | ES2343855T3 (ja) |
GB (1) | GB0500787D0 (ja) |
MX (1) | MX2007008537A (ja) |
NZ (1) | NZ560201A (ja) |
PL (1) | PL1835939T3 (ja) |
PT (1) | PT1835939E (ja) |
RU (1) | RU2429011C2 (ja) |
SI (1) | SI1835939T1 (ja) |
WO (1) | WO2006075170A1 (ja) |
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GB0302218D0 (en) * | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
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-
2005
- 2005-01-14 GB GBGB0500787.7A patent/GB0500787D0/en not_active Ceased
-
2006
- 2006-01-13 BR BRPI0606523-6A patent/BRPI0606523A2/pt not_active Application Discontinuation
- 2006-01-13 WO PCT/GB2006/000120 patent/WO2006075170A1/en active Application Filing
- 2006-01-13 EP EP10075124A patent/EP2193810A1/en not_active Ceased
- 2006-01-13 US US11/795,229 patent/US8529908B2/en active Active
- 2006-01-13 PL PL06700004T patent/PL1835939T3/pl unknown
- 2006-01-13 DK DK06700004.2T patent/DK1835939T3/da active
- 2006-01-13 RU RU2007130774/15A patent/RU2429011C2/ru active
- 2006-01-13 PT PT06700004T patent/PT1835939E/pt unknown
- 2006-01-13 JP JP2007550844A patent/JP5687405B2/ja active Active
- 2006-01-13 NZ NZ560201A patent/NZ560201A/en active Application Revival
- 2006-01-13 DE DE602006013406T patent/DE602006013406D1/de active Active
- 2006-01-13 EP EP06700004A patent/EP1835939B1/en not_active Revoked
- 2006-01-13 MX MX2007008537A patent/MX2007008537A/es active IP Right Grant
- 2006-01-13 CN CNA2006800050964A patent/CN101163508A/zh active Pending
- 2006-01-13 SI SI200630704T patent/SI1835939T1/sl unknown
- 2006-01-13 AU AU2006205656A patent/AU2006205656B2/en active Active
- 2006-01-13 CN CN201510442950.4A patent/CN105126097A/zh active Pending
- 2006-01-13 ES ES06700004T patent/ES2343855T3/es active Active
- 2006-01-13 CA CA2595128A patent/CA2595128C/en active Active
- 2006-01-13 AT AT06700004T patent/ATE463261T1/de active
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2010
- 2010-06-28 CY CY20101100594T patent/CY1110140T1/el unknown
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2012
- 2012-06-06 JP JP2012128887A patent/JP2012162580A/ja not_active Withdrawn
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2014
- 2014-05-20 JP JP2014104349A patent/JP2014144984A/ja not_active Withdrawn
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