JP2007532546A5 - - Google Patents

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Publication number
JP2007532546A5
JP2007532546A5 JP2007507409A JP2007507409A JP2007532546A5 JP 2007532546 A5 JP2007532546 A5 JP 2007532546A5 JP 2007507409 A JP2007507409 A JP 2007507409A JP 2007507409 A JP2007507409 A JP 2007507409A JP 2007532546 A5 JP2007532546 A5 JP 2007532546A5
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JP
Japan
Prior art keywords
oxo
oct
amide
isopropyl
azabicyclo
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JP2007507409A
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English (en)
Japanese (ja)
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JP4944012B2 (ja
JP2007532546A (ja
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Priority claimed from PCT/US2005/011393 external-priority patent/WO2005100350A1/en
Publication of JP2007532546A publication Critical patent/JP2007532546A/ja
Publication of JP2007532546A5 publication Critical patent/JP2007532546A5/ja
Application granted granted Critical
Publication of JP4944012B2 publication Critical patent/JP4944012B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007507409A 2004-04-07 2005-04-06 ５−ｈｔ４レセプターアゴニストとしてのキノリノン−カルボキサミド化合物 Expired - Lifetime JP4944012B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56007604P 2004-04-07 2004-04-07
US60/560,076 2004-04-07
PCT/US2005/011393 WO2005100350A1 (en) 2004-04-07 2005-04-06 Quinolinone-carboxamide compounds as 5-ht4 receptor agonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008076685A Division JP2008174569A (ja) 2004-04-07 2008-03-24 ５−ｈｔ４レセプターアゴニストとしてのキノリノン−カルボキサミド化合物

Publications (3)

Publication Number Publication Date
JP2007532546A JP2007532546A (ja) 2007-11-15
JP2007532546A5 true JP2007532546A5 (https=) 2008-05-15
JP4944012B2 JP4944012B2 (ja) 2012-05-30

Family

ID=34964334

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007507409A Expired - Lifetime JP4944012B2 (ja) 2004-04-07 2005-04-06 ５−ｈｔ４レセプターアゴニストとしてのキノリノン−カルボキサミド化合物
JP2008076685A Withdrawn JP2008174569A (ja) 2004-04-07 2008-03-24 ５−ｈｔ４レセプターアゴニストとしてのキノリノン−カルボキサミド化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008076685A Withdrawn JP2008174569A (ja) 2004-04-07 2008-03-24 ５−ｈｔ４レセプターアゴニストとしてのキノリノン−カルボキサミド化合物

Country Status (28)

Country Link
US (9) US7375114B2 (https=)
EP (1) EP1735304B1 (https=)
JP (2) JP4944012B2 (https=)
KR (1) KR101167296B1 (https=)
CN (1) CN100569771C (https=)
AR (1) AR050407A1 (https=)
AT (1) ATE420088T1 (https=)
AU (1) AU2005233560B2 (https=)
BR (1) BRPI0509761B8 (https=)
CA (1) CA2561558C (https=)
CY (1) CY1108908T1 (https=)
DE (1) DE602005012249D1 (https=)
DK (1) DK1735304T3 (https=)
ES (1) ES2320907T3 (https=)
HR (1) HRP20090162T1 (https=)
IL (1) IL178086A (https=)
MA (1) MA28559B1 (https=)
MX (1) MXPA06011398A (https=)
MY (1) MY155036A (https=)
NO (1) NO337126B1 (https=)
NZ (1) NZ549941A (https=)
PL (1) PL1735304T3 (https=)
PT (1) PT1735304E (https=)
RU (1) RU2394033C2 (https=)
SI (1) SI1735304T1 (https=)
TW (1) TWI351282B (https=)
WO (1) WO2005100350A1 (https=)
ZA (1) ZA200608363B (https=)

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ATE441646T1 (de) * 2004-11-05 2009-09-15 Theravance Inc 5-ht4-rezeptoragonistenverbindungen
ATE469897T1 (de) * 2004-12-22 2010-06-15 Theravance Inc Indazolcarbonsäureamidverbindungen
NZ560828A (en) * 2005-03-02 2011-01-28 Theravance Inc Quinolinone compounds as 5-HT4 receptor agonists
TWI377206B (en) * 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
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AU2008254999A1 (en) * 2007-05-17 2008-11-27 Theravance, Inc. Prokinetic agent for bowel preparation
TWI415850B (zh) 2007-07-20 2013-11-21 Theravance Inc 製備ｍｕ類鴉片受體拮抗劑之中間物的方法
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
CA2758321A1 (en) * 2009-04-13 2010-10-21 Theravance, Inc. 5-ht4 receptor agonist compounds for treatment of cognitive disorders
JP5540099B2 (ja) * 2009-09-14 2014-07-02 スベン ライフ サイエンシズ リミティド ５−ｈｔ４受容体リガンドとしての１，２−ジヒドロ−２−オキソキノリン化合物
JP2013518085A (ja) 2010-02-01 2013-05-20 ノバルティス アーゲー ＣＲＦ−１受容体アンタゴニストとしてのピラゾロ［５，１ｂ］オキサゾール誘導体
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
JP5748777B2 (ja) 2010-02-02 2015-07-15 ノバルティス アーゲー Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
UY34094A (es) 2011-05-27 2013-01-03 Novartis Ag Derivados de la piperidina 3-espirocíclica como agonistas de receptores de la ghrelina
CA2867043A1 (en) 2012-05-03 2013-11-07 Novartis Ag L-malate salt of 2,7-diaza-spiro[4.5]dec-7-yle derivatives and crystalline forms thereof as ghrelin receptor agonists
BR112020000482A2 (pt) * 2017-07-31 2020-07-21 Theravance Biopharma R&D Ip, Llc métodos de tratamento de sintomas de gastroparesia usando velusetrag
RU2764243C2 (ru) 2017-09-22 2022-01-14 ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи Гетероциклические соединения в качестве ингибиторов PAD
AU2018352142B2 (en) 2017-10-18 2022-08-25 Jubilant Epipad LLC Imidazo-pyridine compounds as PAD inhibitors
US11629135B2 (en) 2017-11-06 2023-04-18 Jubilant Prodell Llc Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
PT3704120T (pt) 2017-11-24 2024-07-03 Jubilant Episcribe Llc Compostos heterocíclicos como inibidores de prmt5
MX2020009517A (es) 2018-03-13 2021-01-20 Jubilant Prodel LLC Compuestos biciclicos como inhibidores de la interaccion/activacio n de pdl/pd-l1.
US12275746B2 (en) 2022-01-11 2025-04-15 Suven Life Sciences Limited Pyrrolo[1,2-b]-2-pyridazinone compounds as 5-HT4 receptor agonists
EP4590303A1 (en) 2022-09-20 2025-07-30 Alfasigma S.p.A. Velusetrag for use in the treatment of chronic intestinal pseudo-obstruction (cipo)

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ATE441646T1 (de) * 2004-11-05 2009-09-15 Theravance Inc 5-ht4-rezeptoragonistenverbindungen
ATE469897T1 (de) 2004-12-22 2010-06-15 Theravance Inc Indazolcarbonsäureamidverbindungen
NZ560828A (en) 2005-03-02 2011-01-28 Theravance Inc Quinolinone compounds as 5-HT4 receptor agonists
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