JP2007529426A5 - - Google Patents
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- JP2007529426A5 JP2007529426A5 JP2007503101A JP2007503101A JP2007529426A5 JP 2007529426 A5 JP2007529426 A5 JP 2007529426A5 JP 2007503101 A JP2007503101 A JP 2007503101A JP 2007503101 A JP2007503101 A JP 2007503101A JP 2007529426 A5 JP2007529426 A5 JP 2007529426A5
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- Prior art keywords
- cancer
- disease
- och
- alkyl
- compound
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55269204P | 2004-03-12 | 2004-03-12 | |
| US56279304P | 2004-04-16 | 2004-04-16 | |
| PCT/US2005/008384 WO2005089256A2 (en) | 2004-03-12 | 2005-03-11 | Antiangiogenic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007529426A JP2007529426A (ja) | 2007-10-25 |
| JP2007529426A5 true JP2007529426A5 (https=) | 2008-04-24 |
Family
ID=34994222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503101A Pending JP2007529426A (ja) | 2004-03-12 | 2005-03-11 | 抗血管新生薬 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7498322B2 (https=) |
| EP (1) | EP1756139A4 (https=) |
| JP (1) | JP2007529426A (https=) |
| AU (1) | AU2005222934B2 (https=) |
| CA (1) | CA2558014A1 (https=) |
| WO (1) | WO2005089256A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6346510B1 (en) | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
| JP2006526025A (ja) | 2003-05-28 | 2006-11-16 | エントレメッド インコーポレイテッド | 抗血管新生剤 |
| US7498322B2 (en) | 2004-03-12 | 2009-03-03 | Entremed, Inc. | Antiangiogenic agents |
| US7419972B2 (en) | 2004-07-02 | 2008-09-02 | Schering Ag | 2-substituted estra-1,3,5(10)-trien-17-ones as inhibitors of 17β-hydroxy steroid dehydrogenase type 1 |
| DE102004032674A1 (de) * | 2004-07-02 | 2006-01-26 | Schering Ag | Neue 2-substituierte Estra-1,3,5(10)-trien-17-one als Inhibitoren der 17β-Hydroxysteroiddehydrogenase Typ 1 |
| WO2006058298A2 (en) * | 2004-11-29 | 2006-06-01 | Entremed, Inc. | A method of administering anti-angiogenic agents and a method of treating disease using same |
| GB2430364A (en) * | 2005-09-22 | 2007-03-28 | Carl Ernest Alexander | Soft agar bolus for oral drug delivery |
| US10174070B2 (en) | 2005-09-30 | 2019-01-08 | Endece Llc | 6-substituted estradiol derivatives and methods of use |
| US20070185069A1 (en) * | 2005-11-14 | 2007-08-09 | Plum Stacy M | Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents |
| WO2007109312A2 (en) * | 2006-03-20 | 2007-09-27 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
| CA2674865A1 (en) * | 2007-01-15 | 2008-07-24 | Santen Pharmaceutical Co., Ltd. | Indole derivative having i.kappa.b kinase .beta. inhibitory activity |
| US20080234243A1 (en) * | 2007-01-31 | 2008-09-25 | Lavallee Theresa M | Method of treating amyloidosis mediated diseases |
| US8445529B2 (en) * | 2008-07-14 | 2013-05-21 | Santen Pharmaceutical Co., Ltd. | Indole derivative having, carbamoyl group, ureido group and substituted oxy group |
| US20100113404A1 (en) * | 2008-10-31 | 2010-05-06 | Theresa Lavallee | Anti-angiogenic activity of 2-methoxyestradiol analogs in combination with anti-cancer agents |
| DE102011083725A1 (de) * | 2011-09-29 | 2013-04-04 | Bayer Pharma AG | Estra-1,3,5(10),16-tetraen-3-carboxamid-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln |
| US9512169B2 (en) | 2012-07-10 | 2016-12-06 | Bayer Pharma Aktiengesellschaft | 3-substituted estra-1,3,5(10),16-tetraene derivatives, methods for the production thereof, pharmaceutical preparations containing same, and use thereof for the production of medicaments |
| EA201500851A1 (ru) | 2013-02-21 | 2016-02-29 | Байер Фарма Акциенгезельшафт | ЭСТРА-1,3,5(10),16-ТЕТРАЕН-3-КАРБОКСАМИДЫ ДЛЯ ИНГИБИРОВАНИЯ 17β-ГИДРОКСИСТЕРОИД-ДЕГИДРОГЕНАЗЫ (AKR1C3) |
| RS56621B1 (sr) * | 2014-12-30 | 2018-03-30 | Curadis Gmbh | C-19 steroidi za inhibiranje neovaskularizacije |
| CN104557602B (zh) * | 2015-01-07 | 2016-08-17 | 华东师范大学 | 三环二萜衍生物及其制备方法、及其在制备抗肿瘤药物中的应用 |
Family Cites Families (133)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2584271A (en) * | 1948-06-19 | 1952-02-05 | Searle & Co | Steroid derivatives and method for producing the same |
| GB857081A (en) | 1956-05-29 | 1960-12-29 | Syntex Sa | Cyclopentanophenanthrene derivatives and process for the production thereof |
| US3166577A (en) * | 1956-05-29 | 1965-01-19 | Syntex Corp | 1, 2-dimethyl estrogens and intermediates used in the production thereof |
| GB857080A (en) | 1956-05-29 | 1960-12-29 | Syntex Sa | Cyclopentanophenanthrene derivatives and process for the production thereof |
| US2846453A (en) * | 1957-05-28 | 1958-08-05 | Searle & Co | Alpha-ring-acylated estrone derivatives, and corresponding alcohols, their esters, and ethers |
| DE1107664B (de) * | 1959-11-05 | 1961-05-31 | Schering Ag | Verfahren zur Herstellung neuer in 3-Stellung substituierter OEstratriene |
| DE1907330U (de) | 1964-04-13 | 1964-12-23 | Standard Elektrik Lorenz Ag | Maschine zum einfuehren von einlagen in briefumschlaege. |
| US3562260A (en) * | 1965-08-23 | 1971-02-09 | Ormonoterapia Richter Spa | 2-carbonyl-estratrienes and method of their preparation |
| US3470879A (en) * | 1966-01-07 | 1969-10-07 | Meiller Research Inc | Orthopedic shoe construction |
| FR1492181A (fr) * | 1966-06-20 | 1967-08-18 | Materiel Telephonique | Bloc pompe-moteur |
| US3470218A (en) | 1966-12-27 | 1969-09-30 | Allied Chem | New 2-substituted estrogenic steroids |
| US3410879A (en) * | 1967-04-12 | 1968-11-12 | American Home Prod | Process for preparing gonahexaenes |
| US3492321A (en) | 1968-01-22 | 1970-01-27 | Syntex Corp | Cyclopropenyl estra, -1,3,5(10)-trienes |
| US3496272A (en) * | 1968-01-23 | 1970-02-17 | American Home Prod | Ester of 3-(2-propynyloxy)-estradiol |
| GB1502635A (en) * | 1974-02-27 | 1978-03-01 | Schering Ag | Process for splitting steroid ethers |
| JPS5265259A (en) | 1975-11-27 | 1977-05-30 | Takeda Chem Ind Ltd | Synthesis of 16beta-alkylestradiol or its 17-esters |
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2005
- 2005-03-11 US US11/077,977 patent/US7498322B2/en not_active Expired - Fee Related
- 2005-03-11 CA CA002558014A patent/CA2558014A1/en not_active Abandoned
- 2005-03-11 EP EP05736385A patent/EP1756139A4/en not_active Withdrawn
- 2005-03-11 WO PCT/US2005/008384 patent/WO2005089256A2/en not_active Ceased
- 2005-03-11 JP JP2007503101A patent/JP2007529426A/ja active Pending
- 2005-03-11 AU AU2005222934A patent/AU2005222934B2/en not_active Ceased
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2008
- 2008-12-22 US US12/341,068 patent/US8158612B2/en not_active Expired - Fee Related
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