ATE77387T1 - Zyklische kohlenwasserstoffe mit aminoalkylseitenkette. - Google Patents
Zyklische kohlenwasserstoffe mit aminoalkylseitenkette.Info
- Publication number
- ATE77387T1 ATE77387T1 AT88903641T AT88903641T ATE77387T1 AT E77387 T1 ATE77387 T1 AT E77387T1 AT 88903641 T AT88903641 T AT 88903641T AT 88903641 T AT88903641 T AT 88903641T AT E77387 T1 ATE77387 T1 AT E77387T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- formula
- cyclic hydrocarbons
- side chain
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lubricants (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3904287A | 1987-04-16 | 1987-04-16 | |
| US6227687A | 1987-06-15 | 1987-06-15 | |
| EP88903641A EP0356454B1 (de) | 1987-04-16 | 1988-04-01 | Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette |
| PCT/US1988/000978 WO1988008002A1 (en) | 1987-04-16 | 1988-04-01 | Cyclic hydrocarbons with an aminoalkyl sidechain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE77387T1 true ATE77387T1 (de) | 1992-07-15 |
Family
ID=26715768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88903641T ATE77387T1 (de) | 1987-04-16 | 1988-04-01 | Zyklische kohlenwasserstoffe mit aminoalkylseitenkette. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0356454B1 (de) |
| JP (1) | JPH02502997A (de) |
| KR (1) | KR960002913B1 (de) |
| AT (1) | ATE77387T1 (de) |
| AU (1) | AU1628288A (de) |
| DE (1) | DE3872234T2 (de) |
| DK (1) | DK697988A (de) |
| WO (1) | WO1988008002A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
| US5504074A (en) | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
| US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
| US6995278B2 (en) | 2000-08-18 | 2006-02-07 | Entre Med, Inc. | Antiangiogenic agents |
| US7135581B2 (en) | 2000-08-18 | 2006-11-14 | Entremed, Inc. | Antiangiogenic agents |
| AU8838601A (en) * | 2000-11-27 | 2002-06-03 | Entremed Inc | Antiangiogenic agents |
| DE10135027A1 (de) * | 2001-07-18 | 2003-02-06 | Solvay Pharm Gmbh | Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen |
| EP1581095A4 (de) * | 2002-06-27 | 2006-10-18 | Harkness Pharmaceuticals Inc | Therapeutische methoden zur reduzierung der fettablagerung und zur behandlung von damit einhergehenden erkrankungen |
| CA2558014A1 (en) | 2004-03-12 | 2005-09-29 | Entremed, Inc. | Antiangiogenic agents |
| CA2646065C (en) | 2006-03-20 | 2014-01-14 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3107255A (en) * | 1962-08-03 | 1963-10-15 | Searle & Co | Nu-(dialkylaminoalkyl) androstanyl-17beta-amines, nu-alkyl derivatives thereof, and 2, 3-dehydro compounds corresponding |
| US4917826A (en) * | 1985-10-18 | 1990-04-17 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
-
1988
- 1988-04-01 KR KR1019880701683A patent/KR960002913B1/ko active IP Right Grant
- 1988-04-01 AT AT88903641T patent/ATE77387T1/de active
- 1988-04-01 WO PCT/US1988/000978 patent/WO1988008002A1/en active IP Right Grant
- 1988-04-01 AU AU16282/88A patent/AU1628288A/en not_active Abandoned
- 1988-04-01 DE DE8888903641T patent/DE3872234T2/de not_active Expired - Fee Related
- 1988-04-01 JP JP63503552A patent/JPH02502997A/ja active Pending
- 1988-04-01 EP EP88903641A patent/EP0356454B1/de not_active Expired - Lifetime
- 1988-12-15 DK DK697988A patent/DK697988A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0356454B1 (de) | 1992-06-17 |
| DE3872234T2 (de) | 1993-01-07 |
| JPH02502997A (ja) | 1990-09-20 |
| WO1988008002A1 (en) | 1988-10-20 |
| KR960002913B1 (ko) | 1996-02-28 |
| DK697988D0 (da) | 1988-12-15 |
| KR890700599A (ko) | 1989-04-26 |
| AU1628288A (en) | 1988-11-04 |
| EP0356454A1 (de) | 1990-03-07 |
| DE3872234D1 (de) | 1992-07-23 |
| DK697988A (da) | 1989-01-19 |
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