DE3872234T2 - Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette. - Google Patents
Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette.Info
- Publication number
- DE3872234T2 DE3872234T2 DE8888903641T DE3872234T DE3872234T2 DE 3872234 T2 DE3872234 T2 DE 3872234T2 DE 8888903641 T DE8888903641 T DE 8888903641T DE 3872234 T DE3872234 T DE 3872234T DE 3872234 T2 DE3872234 T2 DE 3872234T2
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- formula
- cyclic hydrocarbons
- side chain
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lubricants (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3904287A | 1987-04-16 | 1987-04-16 | |
US6227687A | 1987-06-15 | 1987-06-15 | |
PCT/US1988/000978 WO1988008002A1 (en) | 1987-04-16 | 1988-04-01 | Cyclic hydrocarbons with an aminoalkyl sidechain |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3872234D1 DE3872234D1 (de) | 1992-07-23 |
DE3872234T2 true DE3872234T2 (de) | 1993-01-07 |
Family
ID=26715768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888903641T Expired - Fee Related DE3872234T2 (de) | 1987-04-16 | 1988-04-01 | Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0356454B1 (de) |
JP (1) | JPH02502997A (de) |
KR (1) | KR960002913B1 (de) |
AT (1) | ATE77387T1 (de) |
AU (1) | AU1628288A (de) |
DE (1) | DE3872234T2 (de) |
DK (1) | DK697988A (de) |
WO (1) | WO1988008002A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5504074A (en) | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
US7135581B2 (en) | 2000-08-18 | 2006-11-14 | Entremed, Inc. | Antiangiogenic agents |
US6995278B2 (en) | 2000-08-18 | 2006-02-07 | Entre Med, Inc. | Antiangiogenic agents |
JP2004537499A (ja) * | 2000-11-27 | 2004-12-16 | エントレメッド インコーポレイテッド | 抗血管新生薬 |
DE10135027A1 (de) * | 2001-07-18 | 2003-02-06 | Solvay Pharm Gmbh | Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen |
AU2003248794B2 (en) * | 2002-06-27 | 2007-10-04 | Harkness Pharmaceuticals, Inc. | Therapeutic methods for reducing fat deposition and treating associated conditions |
CA2558014A1 (en) | 2004-03-12 | 2005-09-29 | Entremed, Inc. | Antiangiogenic agents |
US8399440B2 (en) | 2006-03-20 | 2013-03-19 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3107255A (en) * | 1962-08-03 | 1963-10-15 | Searle & Co | Nu-(dialkylaminoalkyl) androstanyl-17beta-amines, nu-alkyl derivatives thereof, and 2, 3-dehydro compounds corresponding |
WO1987002367A2 (en) * | 1985-10-18 | 1987-04-23 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
-
1988
- 1988-04-01 WO PCT/US1988/000978 patent/WO1988008002A1/en active IP Right Grant
- 1988-04-01 DE DE8888903641T patent/DE3872234T2/de not_active Expired - Fee Related
- 1988-04-01 EP EP88903641A patent/EP0356454B1/de not_active Expired - Lifetime
- 1988-04-01 JP JP63503552A patent/JPH02502997A/ja active Pending
- 1988-04-01 KR KR1019880701683A patent/KR960002913B1/ko active IP Right Grant
- 1988-04-01 AU AU16282/88A patent/AU1628288A/en not_active Abandoned
- 1988-04-01 AT AT88903641T patent/ATE77387T1/de active
- 1988-12-15 DK DK697988A patent/DK697988A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR890700599A (ko) | 1989-04-26 |
EP0356454B1 (de) | 1992-06-17 |
DK697988A (da) | 1989-01-19 |
AU1628288A (en) | 1988-11-04 |
JPH02502997A (ja) | 1990-09-20 |
EP0356454A1 (de) | 1990-03-07 |
WO1988008002A1 (en) | 1988-10-20 |
DK697988D0 (da) | 1988-12-15 |
KR960002913B1 (ko) | 1996-02-28 |
ATE77387T1 (de) | 1992-07-15 |
DE3872234D1 (de) | 1992-07-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1107956T1 (el) | Χρηση υποκατεστημενων 2-αμινοτετραλινιων για την προληπτικη αντιμετωπιση της νοσου του παρκινσον | |
DE3872234D1 (de) | Zyklische kohlenwasserstoffe mit aminoalkyl-seitenkette. | |
DE69625157D1 (de) | Behandlung des typ ii-deabetes mellitus mit amylinagonisten | |
DE69133156T2 (de) | Behandlung von gemütskrankheiten mit funktionellen antagonisten des glycin/nmda-rezeptorkomplexes | |
ES2069014T3 (es) | 11-acilprostaglandinas que reducen la presion intraocular. | |
EA200601295A1 (ru) | Производные 1,3-диоксана и их аналоги, применимые для лечения i.a. ожирения и диабета | |
ATE115573T1 (de) | Neue stilbenderivate, ihre herstellung und verwendung für heilmittel. | |
NO20014925D0 (no) | Farmasöytiske forbindelser | |
ATE25977T1 (de) | Furanonderivate, verfahren zu ihrer herstellung und ihre verwendung. | |
DE59209162D1 (de) | Verwendung von Schwefel enthaltenden Carbonsäuren zur Bekämpfung von pathophysiologisch bedingten Erregungsstörungen | |
DE69634961D1 (de) | Neue zyklische depsipeptid pf1022 derivate | |
EA200500348A1 (ru) | N-арилпиперидинзамещенные бифенилкарбоксамиды в качестве ингибиторов секреции аполипопротеина b | |
ES2060239T3 (es) | Analogos de bis(alquil-sustituido-4-hidroxifeniltio)alcano como inhibidores de la formacion de cataratas. | |
FR2446838A1 (fr) | Derives peptidiques d'acides phosphoniques | |
FI882359A (fi) | Cykliska antikoagulationspeptider. pi path slues6208 s880524 mlues6205 m881102 | |
PT87536A (pt) | Process for the preparation of cyclic anticoagulant peptides | |
AR028802A1 (es) | El uso de ciertos compuestos de ftalazina para el tratamiento de enfermedades neovasculares oculares | |
DE60227421D1 (de) | Rmazeutische zusammensetzung und verwendung davon | |
KR900012903A (ko) | 피롤리딘 화합물 및 약제학적 용도 | |
MXPA05004845A (es) | N-oxidos y derivados de melfalan para el tratamiento de estados de enfermedad asociados a un factor inducible por hipoxia. | |
DK360388A (da) | Laegemiddel til behandling af hjerteinsufficiens | |
DK0865278T3 (da) | Anvendelse af 1-hydroxy-2-pyridoner til behandling af slimhinde-sygdomme, som er vanskeligt at behandle | |
TH59492B (th) | "สารประกอบที่เป็นประโยชน์สำหรับการบำบัด หรือป้องกันโรคที่เป็นสื่อโดยแอลฟา-2b- เอดรีโนเซฟเทอร์" | |
ES2035767B1 (es) | Procedimiento de obtencion de 2-hidroximetil-3,5-dimetilpiridinas 4-sustituidas. | |
RU2003110579A (ru) | Гетероциклические соединения, связывающие хемокиновый рецептор |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |