AR028802A1 - El uso de ciertos compuestos de ftalazina para el tratamiento de enfermedades neovasculares oculares - Google Patents

El uso de ciertos compuestos de ftalazina para el tratamiento de enfermedades neovasculares oculares

Info

Publication number
AR028802A1
AR028802A1 ARP990104021A ARP990104021A AR028802A1 AR 028802 A1 AR028802 A1 AR 028802A1 AR P990104021 A ARP990104021 A AR P990104021A AR P990104021 A ARP990104021 A AR P990104021A AR 028802 A1 AR028802 A1 AR 028802A1
Authority
AR
Argentina
Prior art keywords
treatment
ftalazine
compounds
certain
ocular neovascular
Prior art date
Application number
ARP990104021A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22460608&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR028802(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR028802A1 publication Critical patent/AR028802A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Uso de un compuesto o una sal del mismo, de formula 1 en donde: n es de 0 a 2, R es H o alquilo inferior; X es imino, oxa, o tia; Y es arilo; y Z es piridilo insustituido o sustituido, o un N- oxido del compuesto definido, en donde uno o más átomos de N llevan un átomo de oxígeno; que es para la manufactura de un medicamento util para el tratamiento o la prevencion de enfermedades neovasculares oculares; para la manufactura de medicamentos para el tratamiento o prevencion de enfermedades de neovascularizacion ocular.
ARP990104021A 1998-08-13 1999-08-11 El uso de ciertos compuestos de ftalazina para el tratamiento de enfermedades neovasculares oculares AR028802A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13385598A 1998-08-13 1998-08-13

Publications (1)

Publication Number Publication Date
AR028802A1 true AR028802A1 (es) 2003-05-28

Family

ID=22460608

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990104021A AR028802A1 (es) 1998-08-13 1999-08-11 El uso de ciertos compuestos de ftalazina para el tratamiento de enfermedades neovasculares oculares

Country Status (12)

Country Link
EP (1) EP1105136B1 (es)
JP (1) JP2002522475A (es)
AR (1) AR028802A1 (es)
AT (1) ATE371453T1 (es)
AU (1) AU5733099A (es)
CY (1) CY1107780T1 (es)
DE (1) DE69936994T2 (es)
DK (1) DK1105136T3 (es)
ES (1) ES2291041T3 (es)
PT (1) PT1105136E (es)
TW (1) TWI239243B (es)
WO (1) WO2000009098A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
ES2289791T3 (es) 1997-08-22 2008-02-01 Astrazeneca Ab Derivados de oxindolilquinazolina como inhibidores de la angiogenesis.
ES2265929T3 (es) * 1999-03-30 2007-03-01 Novartis Ag Derivados de ftalazina para el tratamiento de enfermedades inflamatorias.
US7087608B2 (en) * 2000-03-03 2006-08-08 Robert Charles Atkins Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
EP1434991B1 (en) 2001-06-29 2007-10-17 AB Science New potent, selective and non toxic c-kit inhibitors
ATE343415T1 (de) 2001-06-29 2006-11-15 Ab Science Die verwendung von c-kit hemmer zur behandlung von entzündlichen darmerkrankungen
US7700610B2 (en) 2001-06-29 2010-04-20 Ab Science Use of tyrosine kinase inhibitors for treating allergic diseases
PT1401415E (pt) 2001-06-29 2006-09-29 Ab Science Utilizacao de derivados de n-fenil-2-pirimidino-amina para o tratamento de doencas inflamatorias
GB0122318D0 (en) * 2001-09-14 2001-11-07 Novartis Ag Organic compounds
CA2461183A1 (en) * 2001-09-20 2003-05-15 Ab Science Use of tyrosine kinase inhibitors for whitening human skin and treating melanocyte dysfunction associated diseases
BR0308053A (pt) * 2002-02-28 2004-12-28 Novartis Ag Stents revestidos com n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina
WO2003092696A1 (en) * 2002-04-30 2003-11-13 Novartis Ag Method for decreasing capillary permeability in the retina
EP2125895B1 (en) 2007-02-02 2015-04-08 Vegenics Pty Ltd Vegf receptor antagonists for treating organ transplant alloimmunity and arteriosclerosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09316099A (ja) * 1995-08-21 1997-12-09 Mitsui Petrochem Ind Ltd 抗ｖｅｇｆヒトモノクローナル抗体
WO1997034876A1 (en) * 1996-03-15 1997-09-25 Zeneca Limited Cinnoline derivatives and use as medicine
WO1997034920A1 (en) * 1996-03-21 1997-09-25 Sugen, Inc. Assays for kdr/flk-1 receptor tyrosine kinase inhibitors
UA54427C2 (uk) * 1996-05-01 2003-03-17 Елі Ліллі Енд Компані Спосіб лікування очних захворювань, які пов'язані з фактором васкулярного ендотеліального росту
JPH1031019A (ja) * 1996-07-15 1998-02-03 Toagosei Co Ltd 糖尿病性血管新生緑内障の検査方法及び検査薬
US6809097B1 (en) * 1996-09-25 2004-10-26 Zeneca Limited Quinoline derivatives inhibiting the effect of growth factors such as VEGF
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion

Also Published As

Publication number Publication date
JP2002522475A (ja) 2002-07-23
WO2000009098A2 (en) 2000-02-24
EP1105136B1 (en) 2007-08-29
TWI239243B (en) 2005-09-11
CY1107780T1 (el) 2013-06-19
PT1105136E (pt) 2007-12-03
ES2291041T3 (es) 2008-02-16
DE69936994T2 (de) 2008-06-05
AU5733099A (en) 2000-03-06
EP1105136A2 (en) 2001-06-13
ATE371453T1 (de) 2007-09-15
DK1105136T3 (da) 2007-10-15
DE69936994D1 (de) 2007-10-11
WO2000009098A3 (en) 2000-05-18

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