NO980531D0 - Medikament for hemming av avhengighets og toleranse utviklet som fölge av et narkotisk smertestillende middel - Google Patents

Medikament for hemming av avhengighets og toleranse utviklet som fölge av et narkotisk smertestillende middel

Info

Publication number
NO980531D0
NO980531D0 NO980531A NO980531A NO980531D0 NO 980531 D0 NO980531 D0 NO 980531D0 NO 980531 A NO980531 A NO 980531A NO 980531 A NO980531 A NO 980531A NO 980531 D0 NO980531 D0 NO 980531D0
Authority
NO
Norway
Prior art keywords
addiction
drugs
inhibition
result
narcotic
Prior art date
Application number
NO980531A
Other languages
English (en)
Other versions
NO980531L (no
NO315078B1 (no
Inventor
Toshitaka Nabeshima
Mitsunobu Yoshii
Tadashi Shiotani
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO980531D0 publication Critical patent/NO980531D0/no
Publication of NO980531L publication Critical patent/NO980531L/no
Publication of NO315078B1 publication Critical patent/NO315078B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19980531A 1995-08-07 1998-02-06 Anvendelse av en kjemisk forbindelse for fremstilling av et medikament forå hemme avhengighet og toleranse utviklet ved narkotisksmertestillende middel NO315078B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20076395 1995-08-07
PCT/JP1996/002207 WO1997006139A1 (fr) 1995-08-07 1996-08-06 Inhibiteur de la dependance / de la resistance a l'egard des analgesiques narcotiques

Publications (3)

Publication Number Publication Date
NO980531D0 true NO980531D0 (no) 1998-02-06
NO980531L NO980531L (no) 1998-04-06
NO315078B1 NO315078B1 (no) 2003-07-07

Family

ID=16429771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980531A NO315078B1 (no) 1995-08-07 1998-02-06 Anvendelse av en kjemisk forbindelse for fremstilling av et medikament forå hemme avhengighet og toleranse utviklet ved narkotisksmertestillende middel

Country Status (13)

Country Link
US (1) US6107330A (no)
EP (1) EP0844241B1 (no)
KR (1) KR19990036248A (no)
CN (1) CN1085979C (no)
AT (1) ATE231491T1 (no)
AU (1) AU6631396A (no)
CA (1) CA2228813A1 (no)
DE (1) DE69625913T2 (no)
DK (1) DK0844241T3 (no)
ES (1) ES2191763T3 (no)
NO (1) NO315078B1 (no)
TW (1) TW457087B (no)
WO (1) WO1997006139A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000048847A (ko) * 1996-10-01 2000-07-25 스즈키 다다시 미토콘드리아 막 안정화제
WO1999003466A1 (fr) * 1997-07-15 1999-01-28 Daiichi Pharmaceutical Co., Ltd. Substance prophylactique ou therapeutique contre l'amnesie
US6890951B2 (en) 1998-08-05 2005-05-10 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
US20040077709A1 (en) * 1999-05-31 2004-04-22 Daiichi Pharmaceutical Co., Ltd. Neuronal death inhibitors
US6423739B1 (en) 2000-02-23 2002-07-23 Daiichi Pharmaceutical Co., Ltd. Method for aiding cerebral recovery following neurodegeneration
US6348489B1 (en) 2000-04-11 2002-02-19 Daiichi Pharmaceutical Co., Ltd. Method of treating traumatic brain injury and other neuronal disorders
KR100823668B1 (ko) * 2000-12-28 2008-04-21 해밀턴 파마슈티컬스 인코포레이티드 신경성 통증 치료 및 예방약
JP4505410B2 (ja) 2002-10-29 2010-07-21 サングキュンクワン ユニヴァースィティ モルヒネへの心理的依存又は耐性を防止及び処置するのに有効成分としてベルベリンを含有する医薬組成物
US20060241144A1 (en) * 2005-04-20 2006-10-26 Albert Cha Method for treating apathy syndrome

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5198317A (en) * 1975-02-21 1976-08-30 22 okisopirorijin 11 iruasetamidochushaekinoseizoho
US4212878A (en) * 1978-01-26 1980-07-15 The Upjohn Company Phenylacetamide derivative analgesics
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
US4490167A (en) * 1979-08-06 1984-12-25 Ciba-Geigy Corporation Oxime derivatives of diphenyl ethers and their use in herbicidal compositions
BE893276A (fr) * 1981-06-01 1982-11-24 Sandoz Sa Nouvelle application therapeutique d'un derive de l'acetamide
US5468749A (en) * 1988-08-30 1995-11-21 Gawin; Frank H. Method for treatment of substance addiction
US5185329A (en) * 1988-08-30 1993-02-09 Bristol-Myers Squibb Company Method for treatment of substance addiction
IL91451A0 (en) * 1988-08-30 1990-04-29 Bristol Myers Co Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
DE415693T1 (de) * 1989-08-28 1991-10-17 Arizona Technology Development Corp., Tucson, Ariz., Us Zusammensetzung und verfahren zur selektiven verstaerkung der opiat-wirkung und verminderung von opiat-toleranz und abhaengigkeit.
IL101514A (en) * 1991-04-10 1996-01-31 Merck & Co Inc History of benzodiazepines and anticoagulants containing cholecystokinin containing them
US5220018A (en) * 1991-04-10 1993-06-15 Merck & Co., Inc. Cholecystokinin antagonists
JPH0517421A (ja) * 1991-07-10 1993-01-26 Yamanouchi Pharmaceut Co Ltd N−置換アミド誘導体
FI102748B1 (fi) * 1992-06-19 1999-02-15 Daiichi Seiyaku Co Menetelmä N-(2,6-dialkyylifenyyli)-2-(2-okso-1-pyrrolidinyyli)asetamidijohdannaisen valmistamiseksi
US5461157A (en) * 1992-06-19 1995-10-24 Daiichi Pharmaceutical Co., Ltd. Process for preparing pyrrolidinylacetamide derivatives

Also Published As

Publication number Publication date
CN1198738A (zh) 1998-11-11
DE69625913D1 (de) 2003-02-27
EP0844241A1 (en) 1998-05-27
DK0844241T3 (da) 2003-05-12
ATE231491T1 (de) 2003-02-15
EP0844241B1 (en) 2003-01-22
CA2228813A1 (en) 1997-02-20
ES2191763T3 (es) 2003-09-16
US6107330A (en) 2000-08-22
NO980531L (no) 1998-04-06
CN1085979C (zh) 2002-06-05
DE69625913T2 (de) 2003-11-27
TW457087B (en) 2001-10-01
EP0844241A4 (en) 1998-11-18
NO315078B1 (no) 2003-07-07
AU6631396A (en) 1997-03-05
WO1997006139A1 (fr) 1997-02-20
KR19990036248A (ko) 1999-05-25

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