JP2007525984A - 連続的灌流および交互接線流による細胞培養の方法 - Google Patents

連続的灌流および交互接線流による細胞培養の方法 Download PDF

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JP2007525984A
JP2007525984A JP2007501239A JP2007501239A JP2007525984A JP 2007525984 A JP2007525984 A JP 2007525984A JP 2007501239 A JP2007501239 A JP 2007501239A JP 2007501239 A JP2007501239 A JP 2007501239A JP 2007525984 A JP2007525984 A JP 2007525984A
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cell
cells
cell culture
perfusion
culture
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ジョン クロウリー，
マイケ ウーベン，
マーティン， ジョセ マニュエル ココ
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DSM IP Assets BV
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P21/00—Preparation of peptides or proteins
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
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    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2007501239A 2004-03-05 2005-03-04 連続的灌流および交互接線流による細胞培養の方法 Pending JP2007525984A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP04075702 2004-03-05
EP04075703 2004-03-05
EP04077656 2004-09-27
EP04077657 2004-09-27
PCT/EP2005/002374 WO2005095578A1 (en) 2004-03-05 2005-03-04 Process for cell culturing by continuous perfusion and alternating tangential flow

Related Child Applications (2)

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JP2011036102A Division JP2011125348A (ja) 2004-03-05 2011-02-22 連続的灌流および交互接線流による細胞培養の方法
JP2011259168A Division JP2012090632A (ja) 2004-03-05 2011-11-28 連続的灌流および交互接線流による細胞培養の方法

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JP2007525984A true JP2007525984A (ja) 2007-09-13
JP2007525984A5 JP2007525984A5 (https=) 2011-04-14

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Application Number Title Priority Date Filing Date
JP2007501239A Pending JP2007525984A (ja) 2004-03-05 2005-03-04 連続的灌流および交互接線流による細胞培養の方法
JP2011036102A Pending JP2011125348A (ja) 2004-03-05 2011-02-22 連続的灌流および交互接線流による細胞培養の方法
JP2011259168A Pending JP2012090632A (ja) 2004-03-05 2011-11-28 連続的灌流および交互接線流による細胞培養の方法
JP2014016778A Expired - Fee Related JP5719947B2 (ja) 2004-03-05 2014-01-31 灌流培養方法の、細胞培養物中の細胞の凝集度合いを減少させるための使用
JP2015209828A Pending JP2016039817A (ja) 2004-03-05 2015-10-26 連続的灌流および交互接線流による細胞培養の方法
JP2017132997A Pending JP2017225443A (ja) 2004-03-05 2017-07-06 連続的灌流および交互接線流による細胞培養の方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2011036102A Pending JP2011125348A (ja) 2004-03-05 2011-02-22 連続的灌流および交互接線流による細胞培養の方法
JP2011259168A Pending JP2012090632A (ja) 2004-03-05 2011-11-28 連続的灌流および交互接線流による細胞培養の方法
JP2014016778A Expired - Fee Related JP5719947B2 (ja) 2004-03-05 2014-01-31 灌流培養方法の、細胞培養物中の細胞の凝集度合いを減少させるための使用
JP2015209828A Pending JP2016039817A (ja) 2004-03-05 2015-10-26 連続的灌流および交互接線流による細胞培養の方法
JP2017132997A Pending JP2017225443A (ja) 2004-03-05 2017-07-06 連続的灌流および交互接線流による細胞培養の方法

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US (3) US8206981B2 (https=)
EP (3) EP2540815A1 (https=)
JP (6) JP2007525984A (https=)
KR (1) KR101050585B1 (https=)
CN (3) CN1930281A (https=)
AU (1) AU2005229359C1 (https=)
CA (1) CA2557046A1 (https=)
DK (1) DK1720972T3 (https=)
ES (1) ES2456015T3 (https=)
IL (2) IL177724A (https=)
PL (1) PL1720972T3 (https=)
PT (1) PT1720972E (https=)
SI (1) SI1720972T1 (https=)
WO (1) WO2005095578A1 (https=)

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JP2013538588A (ja) * 2010-10-05 2013-10-17 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー タンパク質を生産するための方法
KR20150130366A (ko) * 2013-03-15 2015-11-23 젠자임 코포레이션 고-밀도 세포 뱅킹 방법
JP2016054686A (ja) * 2014-09-09 2016-04-21 旭化成メディカル株式会社 培養産生物の回収方法
JP2016514475A (ja) * 2013-03-26 2016-05-23 コヒラス・バイオサイエンシズ・インコーポレイテッド タンパク質産生方法
WO2019181234A1 (ja) * 2018-03-19 2019-09-26 富士フイルム株式会社 生産物の製造方法
JP2021505182A (ja) * 2017-12-11 2021-02-18 アムジェン インコーポレイテッド 二重特異性抗体製品のための連続製造プロセス
JP2021040638A (ja) * 2014-01-29 2021-03-18 アムジエン・インコーポレーテツド 組換えタンパク質のグリコシル化を調節するためのｎ−グリコシル化経路制御因子の過剰発現
JP2022537650A (ja) * 2019-06-13 2022-08-29 アムジエン・インコーポレーテツド 生物製剤の製造における自動化された生物量に基づく灌流制御
WO2024248119A1 (ja) * 2023-05-31 2024-12-05 富士フイルム株式会社 生産物の生産方法

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