|
NZ335276A
(en)
|
1996-10-18 |
2000-09-29 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hepatitis C virus (HCV) NS3 (Non Structural Protein 3) protease
|
|
US7491794B2
(en)
*
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
US8696298B2
(en)
*
|
2003-11-10 |
2014-04-15 |
Brooks Automation, Inc. |
Semiconductor manufacturing process modules
|
|
US8812150B2
(en)
*
|
2003-11-10 |
2014-08-19 |
Brooks Automation, Inc. |
Semiconductor manufacturing process modules
|
|
US10086511B2
(en)
|
2003-11-10 |
2018-10-02 |
Brooks Automation, Inc. |
Semiconductor manufacturing systems
|
|
US7635694B2
(en)
*
|
2004-02-27 |
2009-12-22 |
Schering Corporation |
Cyclobutenedione-containing compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
RU2006134005A
(ru)
*
|
2004-02-27 |
2008-04-10 |
Шеринг Корпорейшн (US) |
Новые соединения, действующие как ингибиторы сериновой протеазы ns3 вируса гепатита с
|
|
US20060281689A1
(en)
*
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
|
US20070021351A1
(en)
*
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
|
WO2006130666A2
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Medicaments and methods combining a hcv protease inhibitor and an akr competitor
|
|
US20060275366A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation
|
|
US8119602B2
(en)
|
2005-06-02 |
2012-02-21 |
Schering Corporation |
Administration of HCV protease inhibitors in combination with food to improve bioavailability
|
|
JP2008545748A
(ja)
*
|
2005-06-02 |
2008-12-18 |
シェーリング コーポレイション |
C型肝炎ウイルスに関連する障害を処置するために有用な徐放処方物
|
|
WO2006130552A2
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis c virus
|
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
|
US20060276407A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US7772178B2
(en)
*
|
2005-06-02 |
2010-08-10 |
Schering Corporation |
Pharmaceutical formulations and methods of treatment using the same
|
|
EP2305696A3
(en)
*
|
2005-07-25 |
2011-10-12 |
Intermune, Inc. |
Macrocyclic inhibitors of Hepatitis C virus replication
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
EA200801050A1
(ru)
|
2005-10-11 |
2008-12-30 |
Интермьюн, Инк. |
Соединения и способы ингибирования репликации вирусного гепатита с
|
|
NZ568324A
(en)
|
2005-11-11 |
2012-01-12 |
Vertex Pharma |
Hepatitis C virus variants
|
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
JP2009536158A
(ja)
*
|
2006-04-11 |
2009-10-08 |
ノバルティス アクチエンゲゼルシャフト |
Hcv阻害剤
|
|
US20080045530A1
(en)
*
|
2006-04-11 |
2008-02-21 |
Trixi Brandl |
Organic Compounds and Their Uses
|
|
EP2518079A3
(en)
|
2006-04-11 |
2012-12-12 |
Novartis AG |
HCV/HIV inhibitors and their uses
|
|
RU2008152171A
(ru)
|
2006-07-05 |
2010-08-10 |
Интермьюн, Инк. (Us) |
Новые ингибиторы вирусной репликации гепатита с
|
|
WO2008019477A1
(en)
|
2006-08-17 |
2008-02-21 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
US20100081672A1
(en)
*
|
2006-12-07 |
2010-04-01 |
Schering Corporation |
Ph sensitive matrix formulation
|
|
EP2139911A2
(en)
*
|
2007-03-23 |
2010-01-06 |
Schering Corporation |
Hydrazido-peptides as inhibitors of hcv ns3-protease
|
|
EP2139854A2
(en)
*
|
2007-03-23 |
2010-01-06 |
Schering Corporation |
P1-nonepimerizable ketoamide inhibitors of hcv ns3 protease
|
|
WO2008137779A2
(en)
*
|
2007-05-03 |
2008-11-13 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
|
CA2686546A1
(en)
|
2007-05-10 |
2008-11-20 |
Intermune, Inc. |
Novel peptide inhibitors of hepatitis c virus replication
|
|
WO2009018657A1
(en)
|
2007-08-03 |
2009-02-12 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
KR101396696B1
(ko)
*
|
2007-10-10 |
2014-05-16 |
노파르티스 아게 |
스피로피롤리딘, 및 hcv 및 hiv 감염에 대한 그의 용도
|
|
US8419332B2
(en)
*
|
2007-10-19 |
2013-04-16 |
Atlas Bolt & Screw Company Llc |
Non-dimpling fastener
|
|
EP2234977A4
(en)
|
2007-12-19 |
2011-04-13 |
Boehringer Ingelheim Int |
VIRAL POLYMERASE INHIBITORS
|
|
RU2490272C2
(ru)
*
|
2008-02-04 |
2013-08-20 |
Айденикс Фармасьютикалз, Инк. |
Макроциклические ингибиторы серинпротеазы
|
|
WO2009142842A2
(en)
|
2008-04-15 |
2009-11-26 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
|
KR20110116136A
(ko)
|
2009-01-07 |
2011-10-25 |
싸이넥시스, 인크. |
Hcv 및 hiv 감염의 치료에 사용하기 위한 사이클로스포린 유도체
|
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
TW201040181A
(en)
|
2009-04-08 |
2010-11-16 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
US20110182850A1
(en)
*
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
JP2012528195A
(ja)
|
2009-05-29 |
2012-11-12 |
メルク・シャープ・アンド・ドーム・コーポレーション |
C型肝炎などの疾患を処置するための3つの結合アリール部分で構成された抗菌性化合物
|
|
AR077712A1
(es)
|
2009-08-05 |
2011-09-14 |
Idenix Pharmaceuticals Inc |
Inhibidores de serina proteasa macrociclica
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
WO2011066241A1
(en)
|
2009-11-25 |
2011-06-03 |
Schering Corporation |
Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
|
|
MY159958A
(en)
|
2009-12-18 |
2017-02-15 |
Idenix Pharmaceuticals Inc |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
|
WO2011087740A1
(en)
|
2009-12-22 |
2011-07-21 |
Schering Corporation |
Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
MA34147B1
(fr)
|
2010-03-09 |
2013-04-03 |
Merck Sharp & Dohme |
Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales
|
|
CA2805440A1
(en)
|
2010-07-26 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
|
|
EP2621279B1
(en)
|
2010-09-29 |
2018-04-04 |
Merck Sharp & Dohme Corp. |
Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
|
|
JP5565320B2
(ja)
*
|
2011-01-06 |
2014-08-06 |
富士通株式会社 |
情報処理装置及び情報処理プログラム
|
|
TW201309690A
(zh)
|
2011-02-10 |
2013-03-01 |
Idenix Pharmaceuticals Inc |
巨環絲胺酸蛋白酶抑制劑,其醫藥組合物及其於治療hcv感染之用途
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
EP2697242B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2012142085A1
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
2'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2012158861A2
(en)
|
2011-05-18 |
2012-11-22 |
Enanta Pharmaceuticals, Inc. |
Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives
|
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
|
US20140378416A1
(en)
|
2011-09-14 |
2014-12-25 |
Michael P. Dwyer |
Silyl-containing heterocyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
EP3046924A1
(en)
|
2013-09-20 |
2016-07-27 |
IDENIX Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015065817A1
(en)
|
2013-10-30 |
2015-05-07 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
|
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
WO2015134560A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
CN104292130B
(zh)
*
|
2014-10-13 |
2016-04-27 |
苏州永健生物医药有限公司 |
一种波普瑞韦中间体2-羟基-3-氨基-4-环丁基丁酰胺盐酸盐的合成方法
|
|
WO2018032467A1
(en)
|
2016-08-18 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Chromane-substitued tetracyclic compounds and uses thereof for treatment of viral diseases
|
|
WO2018032468A1
(en)
|
2016-08-18 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Heterocycle-substitued tetracyclic compounds and methods of use thereof for treatment of viral diseases
|
|
EP4178955A1
(en)
|
2020-07-11 |
2023-05-17 |
Pfizer Inc. |
Antiviral heteroaryl ketone derivatives
|
|
US11351149B2
(en)
|
2020-09-03 |
2022-06-07 |
Pfizer Inc. |
Nitrile-containing antiviral compounds
|
|
US20240336610A1
(en)
*
|
2021-08-02 |
2024-10-10 |
The Global Health Drug Discovery Institute |
3cl protease small-molecule inhibitor for treating or preventing coronavirus infection, and use thereof
|