|
CZ298749B6
(cs)
|
1996-10-18 |
2008-01-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitory serinových proteáz a farmaceutické prostředky s jejich obsahem
|
|
US7491794B2
(en)
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
US10086511B2
(en)
|
2003-11-10 |
2018-10-02 |
Brooks Automation, Inc. |
Semiconductor manufacturing systems
|
|
US8696298B2
(en)
*
|
2003-11-10 |
2014-04-15 |
Brooks Automation, Inc. |
Semiconductor manufacturing process modules
|
|
US8267632B2
(en)
*
|
2003-11-10 |
2012-09-18 |
Brooks Automation, Inc. |
Semiconductor manufacturing process modules
|
|
CN1946691A
(zh)
*
|
2004-02-27 |
2007-04-11 |
先灵公司 |
作为丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的化合物
|
|
US7635694B2
(en)
*
|
2004-02-27 |
2009-12-22 |
Schering Corporation |
Cyclobutenedione-containing compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
US20060281689A1
(en)
*
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
|
ES2572980T3
(es)
*
|
2005-06-02 |
2016-06-03 |
Merck Sharp & Dohme Corp. |
Combinación de inhibidores de la proteasa del VHC con un tensioactivo
|
|
EP1891089B1
(en)
|
2005-06-02 |
2014-11-05 |
Merck Sharp & Dohme Corp. |
HCV protease inhibitors in combination with food
|
|
US20060276404A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
US20060276407A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
|
AU2006252623A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation useful for treating disorders associated with hepatitis C virus
|
|
US20060275366A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation
|
|
WO2006130687A2
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis c virus protease inhibitor
|
|
US20060276406A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
KR101294467B1
(ko)
*
|
2005-07-25 |
2013-09-09 |
인터뮨, 인크. |
Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
BRPI0617274A2
(pt)
|
2005-10-11 |
2011-07-19 |
Intermune Inc |
compostos e métodos para a inibição de replicação viral de hepatite c
|
|
EP1951748B1
(en)
|
2005-11-11 |
2013-07-24 |
Vertex Pharmaceuticals, Inc. |
Hepatitis c virus variants
|
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
US20080045530A1
(en)
*
|
2006-04-11 |
2008-02-21 |
Trixi Brandl |
Organic Compounds and Their Uses
|
|
EP2007788A2
(en)
*
|
2006-04-11 |
2008-12-31 |
Novartis AG |
Hcv inhibitors
|
|
UA100666C2
(uk)
|
2006-04-11 |
2013-01-25 |
Новартіс Аг |
Інгібітори нсv/віл та їх застосування
|
|
RU2008152171A
(ru)
|
2006-07-05 |
2010-08-10 |
Интермьюн, Инк. (Us) |
Новые ингибиторы вирусной репликации гепатита с
|
|
EP2054388A4
(en)
|
2006-08-17 |
2009-10-28 |
Boehringer Ingelheim Int |
VIRAL POLYMERASE INHIBITORS
|
|
WO2008073282A2
(en)
|
2006-12-07 |
2008-06-19 |
Schering Corporation |
Ph sensitive matrix formulation
|
|
WO2009008913A2
(en)
*
|
2007-03-23 |
2009-01-15 |
Schering Corporation |
P1-nonepimerizable ketoamide inhibitors of hcv ns3 protease
|
|
MX2009010207A
(es)
*
|
2007-03-23 |
2009-10-19 |
Schering Corp |
Peptidos de hidrazido como inhibidores de proteasa ns3 de virus de hepatitis c.
|
|
SG174809A1
(en)
*
|
2007-05-03 |
2011-10-28 |
Intermune Inc |
Macrocyclic compounds useful as inhibitors of hepatitis c virus
|
|
AU2008251425A1
(en)
|
2007-05-10 |
2008-11-20 |
Array Biopharma, Inc. |
Novel peptide inhibitors of hepatitis C virus replication
|
|
WO2009018657A1
(en)
|
2007-08-03 |
2009-02-12 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
AU2008309589B2
(en)
|
2007-10-10 |
2012-07-05 |
Novartis Ag |
Spiropyrrolidines and their use against HCV and HIV infection
|
|
US8419332B2
(en)
*
|
2007-10-19 |
2013-04-16 |
Atlas Bolt & Screw Company Llc |
Non-dimpling fastener
|
|
CN103483251A
(zh)
|
2007-12-19 |
2014-01-01 |
贝林格尔.英格海姆国际有限公司 |
病毒聚合酶抑制剂
|
|
AR070413A1
(es)
|
2008-02-04 |
2010-04-07 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de proteasa de serina
|
|
MX2010011306A
(es)
|
2008-04-15 |
2010-11-09 |
Intermune Inc |
Nuevos inhibidores macrociclicos de la replicacion del virus de la hepatitis c.
|
|
AU2010203656A1
(en)
|
2009-01-07 |
2011-07-21 |
Scynexis, Inc. |
Cyclosporine derivative for use in the treatment of HCV and HIV infection
|
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
WO2010118078A1
(en)
|
2009-04-08 |
2010-10-14 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
|
US20110182850A1
(en)
*
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
CA2763140A1
(en)
|
2009-05-29 |
2010-12-02 |
Schering Corporation |
Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c
|
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
EP2503881B1
(en)
|
2009-11-25 |
2015-05-13 |
Merck Sharp & Dohme Corp. |
Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
|
|
AR079528A1
(es)
|
2009-12-18 |
2012-02-01 |
Idenix Pharmaceuticals Inc |
Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
|
|
WO2011087740A1
(en)
|
2009-12-22 |
2011-07-21 |
Schering Corporation |
Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
AU2011224698A1
(en)
|
2010-03-09 |
2012-11-01 |
Merck Sharp & Dohme Corp. |
Fused Tricyclic Silyl Compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2012018534A2
(en)
|
2010-07-26 |
2012-02-09 |
Schering Corporation |
Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
|
|
CA2812779A1
(en)
|
2010-09-29 |
2012-04-19 |
Merck Sharp & Dohme Corp. |
Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
|
|
JP5565320B2
(ja)
*
|
2011-01-06 |
2014-08-06 |
富士通株式会社 |
情報処理装置及び情報処理プログラム
|
|
WO2012109398A1
(en)
|
2011-02-10 |
2012-08-16 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating hcv infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
EA201391519A1
(ru)
|
2011-04-13 |
2014-03-31 |
Мерк Шарп И Доум Корп. |
2'-замещенные нуклеозидные производные и способы их применения для лечения вирусных заболеваний
|
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
JP5669984B2
(ja)
*
|
2011-05-18 |
2015-02-18 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
５−アザスピロ［２．４］ヘプタン−６−カルボン酸およびその誘導体の製造方法
|
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
|
EP2755981A4
(en)
|
2011-09-14 |
2015-03-25 |
Merck Sharp & Dohme |
SILICULAR HETEROCYCLIC DERIVATIVES AND METHOD FOR THEIR USE FOR THE TREATMENT OF VIRUS DISEASES
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
EP3063140A4
(en)
|
2013-10-30 |
2017-11-08 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
CN104292130B
(zh)
*
|
2014-10-13 |
2016-04-27 |
苏州永健生物医药有限公司 |
一种波普瑞韦中间体2-羟基-3-氨基-4-环丁基丁酰胺盐酸盐的合成方法
|
|
US12577240B2
(en)
|
2020-07-11 |
2026-03-17 |
Pfizer Inc. |
Antiviral heteroaryl ketone derivatives
|
|
US11351149B2
(en)
|
2020-09-03 |
2022-06-07 |
Pfizer Inc. |
Nitrile-containing antiviral compounds
|
|
WO2023011443A1
(zh)
*
|
2021-08-02 |
2023-02-09 |
北京华益健康药物研究中心 |
用于治疗或预防冠状病毒感染的3cl蛋白酶小分子抑制剂及其用途
|