JP2007523151A5 - - Google Patents

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Publication number
JP2007523151A5
JP2007523151A5 JP2006553697A JP2006553697A JP2007523151A5 JP 2007523151 A5 JP2007523151 A5 JP 2007523151A5 JP 2006553697 A JP2006553697 A JP 2006553697A JP 2006553697 A JP2006553697 A JP 2006553697A JP 2007523151 A5 JP2007523151 A5 JP 2007523151A5
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JP
Japan
Prior art keywords
pyrido
ylamino
pyridin
pyrimidin
piperazin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006553697A
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English (en)
Japanese (ja)
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JP2007523151A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2005/000300 external-priority patent/WO2005082903A1/en
Publication of JP2007523151A publication Critical patent/JP2007523151A/ja
Publication of JP2007523151A5 publication Critical patent/JP2007523151A5/ja
Withdrawn legal-status Critical Current

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JP2006553697A 2004-02-18 2005-02-07 ２−（ピリジン−３−イルアミノ）−ピリド［２，３−ｄ］ピリミジン−７−オン Withdrawn JP2007523151A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54536104P 2004-02-18 2004-02-18
PCT/IB2005/000300 WO2005082903A1 (en) 2004-02-18 2005-02-07 2-(pyridin-3-ylamino)-pyrido[2,3-d]pyrimidin-7-ones

Publications (2)

Publication Number Publication Date
JP2007523151A JP2007523151A (ja) 2007-08-16
JP2007523151A5 true JP2007523151A5 (enExample) 2008-02-28

Family

ID=34910727

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006553697A Withdrawn JP2007523151A (ja) 2004-02-18 2005-02-07 ２−（ピリジン−３−イルアミノ）−ピリド［２，３−ｄ］ピリミジン−７−オン

Country Status (6)

Country Link
US (1) US20050182078A1 (enExample)
EP (1) EP1718645A1 (enExample)
JP (1) JP2007523151A (enExample)
BR (1) BRPI0507852A (enExample)
CA (1) CA2555724A1 (enExample)
WO (1) WO2005082903A1 (enExample)

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PT2600719E (pt) 2010-08-05 2014-12-22 Univ Temple 8 ¿ alquilo -2 - substituído 7 ¿ oxo ¿ 7,8 ¿ diidropirido [2,3 ¿ d] pirimidina ¿ 6 ¿ carbonitrilos e seus usos
WO2012088266A2 (en) 2010-12-22 2012-06-28 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
CN103703000B (zh) 2011-03-23 2015-11-25 安姆根有限公司 Cdk4/6和flt3的稠合三环双重抑制剂
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US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
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EP3172214B1 (en) 2014-07-26 2020-05-13 Sunshine Lake Pharma Co., Ltd. 2-amino-pyrido[2,3-d]pyrimidin-7(8h)-one derivatives as cdk inhibitors and uses thereof
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
CR20170390A (es) 2015-02-20 2017-10-23 Incyte Holdings Corp Heterociclos biciclicos como inhibidores de fgfr
US9580423B2 (en) 2015-02-20 2017-02-28 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA45920B1 (fr) 2016-08-15 2021-08-31 Pfizer Inhibiteurs de pyridopyrimidinone cdk2/4/6
CN108191857B (zh) * 2017-01-24 2020-10-23 晟科药业（江苏）有限公司 6-取代的吡啶并[2,3-d]嘧啶类化合物作为蛋白激酶抑制剂
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
CN115322193A (zh) 2017-08-31 2022-11-11 达纳-法伯癌症研究所股份有限公司 Egfr和/或her2抑制剂和使用方法
PE20210919A1 (es) 2018-05-04 2021-05-19 Incyte Corp Sales de un inhibidor de fgfr
BR112020022392A2 (pt) 2018-05-04 2021-02-02 Incyte Corporation formas sólidas de um inibidor de fgfr e processos para preparação das mesmas
WO2020006210A1 (en) * 2018-06-27 2020-01-02 Tufts Medical Center, Inc. Pyridopyrimidine compounds and methods of their use
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US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
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US12122767B2 (en) 2019-10-01 2024-10-22 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
CN119930610A (zh) * 2019-10-11 2025-05-06 因赛特公司 作为cdk2抑制剂的双环胺
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TW202304459A (zh) 2021-04-12 2023-02-01 美商英塞特公司 包含ｆｇｆｒ抑制劑及ｎｅｃｔｉｎ－４靶向劑之組合療法
TW202309030A (zh) 2021-05-07 2023-03-01 美商凱麥拉醫療公司 Cdk2降解劑及其用途
CA3220155A1 (en) 2021-06-09 2022-12-15 Incyte Corporation Tricyclic heterocycles as fgfr inhibitors
TW202313611A (zh) 2021-06-09 2023-04-01 美商英塞特公司 作為ｆｇｆｒ抑制劑之三環雜環
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US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors
CN117430597A (zh) * 2022-07-14 2024-01-23 浙江同源康医药股份有限公司 用作cdk4激酶抑制剂的化合物及其应用

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US5945422A (en) * 1997-02-05 1999-08-31 Warner-Lambert Company N-oxides of amino containing pyrido 2,3-D! pyrimidines
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JP2004505974A (ja) * 2000-08-04 2004-02-26 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー ２−（４−ピリジル）アミノ−６−ジアルキルオキシフェニルピリド〔２，３−ｄ〕ピリミジン−７−オン類の製造方法
ATE303385T1 (de) * 2000-08-04 2005-09-15 Warner Lambert Co Verfahren zur herstellung von 2-(4-pyridyl)amino- 6-dialkylolxaphenyl-pyrido(2,3-d)pyrimidon-7-on derivaten
PL218692B1 (pl) * 2002-01-22 2015-01-30 Warner Lambert Co Podstawiony 2-(pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-on oraz jego zastosowanie do leczenia zaburzenia lub stanu spowodowanego nieprawidłową proliferacją komórek

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