JP2007513632A5 - - Google Patents
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- Publication number
- JP2007513632A5 JP2007513632A5 JP2006544043A JP2006544043A JP2007513632A5 JP 2007513632 A5 JP2007513632 A5 JP 2007513632A5 JP 2006544043 A JP2006544043 A JP 2006544043A JP 2006544043 A JP2006544043 A JP 2006544043A JP 2007513632 A5 JP2007513632 A5 JP 2007513632A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- acid sequence
- trichoderma reesei
- spores
- cel6a cellobiohydrolase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101150084346 wA gene Proteins 0.000 description 4
- 108010008885 Cellulose 1,4-beta-Cellobiosidase Proteins 0.000 description 3
- 101710098246 Exoglucanase 2 Proteins 0.000 description 3
- 241000499912 Trichoderma reesei Species 0.000 description 3
- 241001225321 Aspergillus fumigatus Species 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 229940091771 aspergillus fumigatus Drugs 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 108020004999 messenger RNA Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical group 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- 241000351920 Aspergillus nidulans Species 0.000 description 1
- 240000006439 Aspergillus oryzae Species 0.000 description 1
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 1
- 238000000636 Northern blotting Methods 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 108010030975 Polyketide Synthases Proteins 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000001056 green pigment Substances 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52836703P | 2003-12-09 | 2003-12-09 | |
| US60/528,367 | 2003-12-09 | ||
| PCT/US2004/041510 WO2005056772A1 (en) | 2003-12-09 | 2004-12-09 | Methods for eliminating or reducing the expression of genes in filamentous fungal strains |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007513632A JP2007513632A (ja) | 2007-05-31 |
| JP2007513632A5 true JP2007513632A5 (enExample) | 2011-08-25 |
| JP4842834B2 JP4842834B2 (ja) | 2011-12-21 |
Family
ID=34676840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006544043A Expired - Fee Related JP4842834B2 (ja) | 2003-12-09 | 2004-12-09 | 糸状菌株における遺伝子の発現を排除するか又は低めるための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8716023B2 (enExample) |
| EP (1) | EP1702059B1 (enExample) |
| JP (1) | JP4842834B2 (enExample) |
| CN (2) | CN102174581B (enExample) |
| DK (1) | DK1702059T3 (enExample) |
| WO (1) | WO2005056772A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1702059T3 (da) * | 2003-12-09 | 2013-03-04 | Novozymes Inc | Fremgangsmåder til eliminering og reduktion af ekspression af gener i filamentøse svampestammer |
| WO2006070227A2 (en) * | 2004-10-04 | 2006-07-06 | Devgen Nv | Method for down-regulating gene expression in fungi |
| CA2583460A1 (en) * | 2004-10-15 | 2006-04-20 | Dsm Ip Assets B.V. | Homologous amds genes as selectable marker |
| KR20070085421A (ko) | 2004-10-21 | 2007-08-27 | 벤간자 아이엔씨 | 식물들의 해충들 및 병원균들에 대한 내성을 제공하기 위한방법들 및 물질들 |
| EP1850873B1 (en) | 2005-02-08 | 2018-11-28 | Genzyme Corporation | Antibodies to tgfbeta |
| EP1772522A1 (en) * | 2005-10-04 | 2007-04-11 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Control of preservation by biomarkers |
| GB0602435D0 (en) * | 2006-02-07 | 2006-03-22 | F2G Ltd | Promoter system |
| KR100711516B1 (ko) * | 2006-02-14 | 2007-04-27 | 한양대학교 산학협력단 | 저전력 및 소면적의 용량 결합형 레벨 시프트 회로 |
| WO2008053019A2 (en) * | 2006-11-02 | 2008-05-08 | Dsm Ip Assets B.V. | Method for reducing the expression of a gene in a filamentous fungal cell |
| CN101652479A (zh) * | 2006-12-21 | 2010-02-17 | 诺维信股份有限公司 | 通过移行rna干扰来降低或消除丝状真菌菌株中的基因表达的方法 |
| KR20100029088A (ko) * | 2007-05-31 | 2010-03-15 | 노보자임스 인코포레이티드 | 셀룰로오스성 물질의 분해를 위한 조성물 |
| US20090246844A1 (en) * | 2007-10-26 | 2009-10-01 | Arbor Fuel Inc. | Methods for the production of ethanol |
| US8338121B2 (en) | 2008-12-19 | 2012-12-25 | Novozymes, Inc. | Methods for determining cellulolytic enhancing activity of a polypeptide |
| MX2012005152A (es) | 2009-11-06 | 2012-06-12 | Novozymes Inc | Composiciones para sacrificacion de material celulosico. |
| BR122018077148B1 (pt) | 2009-12-18 | 2020-11-03 | Novozymes, Inc | mutante de uma cepa de trichoderma reesei parental isolada, e, métodos para produzir um polipeptídeo de inetresse e para obter um mutante de uma cepa de trichoderma reesei parental |
| BR112013002979A2 (pt) | 2010-08-12 | 2016-06-07 | Novozymes Inc | composição, e, método para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico. |
| CN107345226A (zh) | 2010-09-30 | 2017-11-14 | 诺维信股份有限公司 | 具有纤维素分解增强活性的多肽变体及其编码多核苷酸 |
| BR112013007693B1 (pt) | 2010-09-30 | 2021-12-07 | Novozymes, Inc | Variante, polinucleotídeo isolado, célula hospedeira microbiana recombinante, métodos para produzir uma variante, para produzir uma variante tendo atividade intensificadora celulolítica, para degradar um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, e, composição enzimática, formulação do caldo completo ou composição de cultura de células |
| DK2640833T3 (en) | 2010-11-18 | 2016-11-28 | Novozymes Inc | Chimeric polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM |
| US8927235B2 (en) | 2010-12-06 | 2015-01-06 | Novozymes A/S | Methods of hydrolyzing oligomers in hemicellulosic liquor |
| US9284588B2 (en) | 2010-12-16 | 2016-03-15 | Novozymes, Inc. | Promoters for expressing genes in a fungal cell |
| EP2794869B1 (en) | 2011-12-20 | 2017-10-04 | Novozymes, Inc. | Cellobiohydrolase variants and polynucleotides encoding same |
| DK2800809T3 (en) | 2012-01-05 | 2018-05-22 | Glykos Finland Oy | PROTEASE-DEFECTED FILAMENTARY FUNGAL CELLS AND PROCEDURES FOR USE THEREOF |
| US9803209B2 (en) | 2012-05-18 | 2017-10-31 | Novozymes A/S | Bacterial mutants with improved transformation efficiency |
| US8945553B2 (en) | 2012-05-22 | 2015-02-03 | Bristol-Myers Squibb Company | Bispecific antibodies to IL-23 and IL-17A/F |
| EP2885409A1 (en) | 2012-08-17 | 2015-06-24 | Novozymes A/S | Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof |
| WO2014068010A1 (en) | 2012-10-31 | 2014-05-08 | Novozymes A/S | Isopropanol production by bacterial hosts |
| WO2014076232A2 (en) | 2012-11-19 | 2014-05-22 | Novozymes A/S | Isopropanol production by recombinant hosts using an hmg-coa intermediate |
| US10023872B2 (en) | 2012-12-21 | 2018-07-17 | Novozymes, Inc. | Methods for producing heterologous polypeptides in mutants of trichoderma |
| WO2015033356A1 (en) * | 2013-09-06 | 2015-03-12 | Council Of Scientific & Industrial Research | Enzyme composition and process of preperation theroff |
| EP3074513A1 (en) | 2013-11-26 | 2016-10-05 | Novozymes A/S | Enzyme compositions and uses thereof |
| WO2015187935A1 (en) | 2014-06-06 | 2015-12-10 | Novozymes A/S | Enzyme compositions and uses thereof |
| US10385352B2 (en) | 2015-03-09 | 2019-08-20 | Novozymes A/S | Methods of introducing multiple expression constructs into a eukaryotic cell |
| CN106566870A (zh) * | 2016-08-31 | 2017-04-19 | 泰山医学院 | 一种高通量快速筛选真菌拮抗细菌的方法 |
| US20220025422A1 (en) | 2018-11-28 | 2022-01-27 | Novozymes A/S | Improved Filamentous Fungal Host Cells |
| CN113302305A (zh) | 2018-12-12 | 2021-08-24 | 诺维信公司 | 提高丝状真菌细胞在多肽的产生方面的生产力的方法 |
| WO2021148278A1 (en) | 2020-01-24 | 2021-07-29 | Novozymes A/S | Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide |
| CN111909929B (zh) * | 2020-08-13 | 2022-09-27 | 中国农业科学院北京畜牧兽医研究所 | 一种靶向获取里氏木霉纤维素酶调控基因的方法 |
| WO2023102315A1 (en) | 2021-12-01 | 2023-06-08 | Danisco Us Inc. | Compositions and methods for enhanced protein production in fungal cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9710475D0 (en) * | 1997-05-21 | 1997-07-16 | Zeneca Ltd | Gene silencing |
| WO2001049844A1 (en) | 1999-12-30 | 2001-07-12 | Rutgers, The State University Of New Jersey | Compositions and methods for gene silencing |
| WO2003050288A1 (en) * | 2001-12-12 | 2003-06-19 | Plant Bioscience Limited | Methods and means for gene silencing in plants |
| CN1176937C (zh) * | 2003-02-21 | 2004-11-24 | 复旦大学附属中山医院 | 一种双链rna及其用途 |
| WO2004091572A2 (en) * | 2003-04-09 | 2004-10-28 | Biodelivery Sciences International, Inc. | Cochleate compositions directed against expression of proteins |
| EP1664298A4 (en) | 2003-09-12 | 2010-03-17 | Commw Scient Ind Res Org | MODIFIED GEN-SILENCING NUCLEIC ACID MOLECULES AND USES THEREOF |
| DK1702059T3 (da) * | 2003-12-09 | 2013-03-04 | Novozymes Inc | Fremgangsmåder til eliminering og reduktion af ekspression af gener i filamentøse svampestammer |
-
2004
- 2004-12-09 DK DK04813775.6T patent/DK1702059T3/da active
- 2004-12-09 EP EP04813775A patent/EP1702059B1/en not_active Expired - Lifetime
- 2004-12-09 JP JP2006544043A patent/JP4842834B2/ja not_active Expired - Fee Related
- 2004-12-09 CN CN201110048625.1A patent/CN102174581B/zh not_active Expired - Fee Related
- 2004-12-09 CN CN200480041520.1A patent/CN1914311B/zh not_active Expired - Fee Related
- 2004-12-09 WO PCT/US2004/041510 patent/WO2005056772A1/en not_active Ceased
- 2004-12-09 US US11/009,890 patent/US8716023B2/en not_active Expired - Fee Related
-
2014
- 2014-04-17 US US14/255,642 patent/US20140287475A1/en not_active Abandoned
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