DK1702059T3 - Fremgangsmåder til eliminering og reduktion af ekspression af gener i filamentøse svampestammer - Google Patents
Fremgangsmåder til eliminering og reduktion af ekspression af gener i filamentøse svampestammerInfo
- Publication number
- DK1702059T3 DK1702059T3 DK04813775.6T DK04813775T DK1702059T3 DK 1702059 T3 DK1702059 T3 DK 1702059T3 DK 04813775 T DK04813775 T DK 04813775T DK 1702059 T3 DK1702059 T3 DK 1702059T3
- Authority
- DK
- Denmark
- Prior art keywords
- genes
- elimination
- expression
- reduction
- methods
- Prior art date
Links
- 230000008030 elimination Effects 0.000 title 1
- 238000003379 elimination reaction Methods 0.000 title 1
- 230000002538 fungal effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52836703P | 2003-12-09 | 2003-12-09 | |
| PCT/US2004/041510 WO2005056772A1 (en) | 2003-12-09 | 2004-12-09 | Methods for eliminating or reducing the expression of genes in filamentous fungal strains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1702059T3 true DK1702059T3 (da) | 2013-03-04 |
Family
ID=34676840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04813775.6T DK1702059T3 (da) | 2003-12-09 | 2004-12-09 | Fremgangsmåder til eliminering og reduktion af ekspression af gener i filamentøse svampestammer |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8716023B2 (enExample) |
| EP (1) | EP1702059B1 (enExample) |
| JP (1) | JP4842834B2 (enExample) |
| CN (2) | CN102174581B (enExample) |
| DK (1) | DK1702059T3 (enExample) |
| WO (1) | WO2005056772A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005056772A1 (en) * | 2003-12-09 | 2005-06-23 | Novozymes Inc. | Methods for eliminating or reducing the expression of genes in filamentous fungal strains |
| WO2006070227A2 (en) * | 2004-10-04 | 2006-07-06 | Devgen Nv | Method for down-regulating gene expression in fungi |
| JP2008516594A (ja) * | 2004-10-15 | 2008-05-22 | ディーエスエム アイピー アセッツ ビー．ブイ． | 選択可能なマーカーとしての相同性ａｍｄｓ遺伝子 |
| EP1807522B1 (en) | 2004-10-21 | 2013-11-20 | Venganza Inc. | Methods and materials for conferring resistance to pests and pathogens of plants |
| MX2007009545A (es) | 2005-02-08 | 2008-03-11 | Genzyme Corp | Anticuerpos para tgfbeta. |
| EP1772522A1 (en) * | 2005-10-04 | 2007-04-11 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Control of preservation by biomarkers |
| GB0602435D0 (en) * | 2006-02-07 | 2006-03-22 | F2G Ltd | Promoter system |
| KR100711516B1 (ko) * | 2006-02-14 | 2007-04-27 | 한양대학교 산학협력단 | 저전력 및 소면적의 용량 결합형 레벨 시프트 회로 |
| WO2008053019A2 (en) * | 2006-11-02 | 2008-05-08 | Dsm Ip Assets B.V. | Method for reducing the expression of a gene in a filamentous fungal cell |
| CN105420268A (zh) * | 2006-12-21 | 2016-03-23 | 诺维信股份有限公司 | 通过移行rna干扰来降低或消除丝状真菌菌株中的基因表达的方法 |
| NZ581257A (en) | 2007-05-31 | 2012-03-30 | Novozymes Inc | Compositions for degrading cellulosic material |
| US20090246844A1 (en) * | 2007-10-26 | 2009-10-01 | Arbor Fuel Inc. | Methods for the production of ethanol |
| US8338121B2 (en) | 2008-12-19 | 2012-12-25 | Novozymes, Inc. | Methods for determining cellulolytic enhancing activity of a polypeptide |
| MX2012005152A (es) | 2009-11-06 | 2012-06-12 | Novozymes Inc | Composiciones para sacrificacion de material celulosico. |
| WO2011075677A2 (en) | 2009-12-18 | 2011-06-23 | Novozymes, Inc. | Methods for producing polypeptides in protease-deficient mutants of trichoderma |
| EP2603596B1 (en) | 2010-08-12 | 2020-10-07 | Novozymes, Inc. | Compositions comprising a polypeptide having cellulolytic enhancing activity and a liquor and uses thereof |
| CN103237891B (zh) | 2010-09-30 | 2017-07-14 | 诺维信股份有限公司 | 具有纤维素分解增强活性的多肽变体及其编码多核苷酸 |
| DK2622068T3 (en) | 2010-09-30 | 2016-10-17 | Novozymes Inc | Variants of polypeptides having cellulolytic enhancing ACTIVITY AND POLYNUCLEOTIDES ENCODING THEM |
| US9676830B2 (en) | 2010-11-18 | 2017-06-13 | Novozymes, Inc. | Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2649188A1 (en) | 2010-12-06 | 2013-10-16 | Novozymes North America, Inc. | Methods of hydrolyzing oligomers in hemicellulosic liquor |
| DK2652138T3 (en) | 2010-12-16 | 2018-01-22 | Novozymes Inc | Promoters for expression of genes in a fungal cell |
| BR112014015228B1 (pt) | 2011-12-20 | 2022-07-05 | Novozymes, Inc. | Variante de celobiohidrolase genitora, processos para degradação ou conversão de um material celulósico, para produção de um produto de fermentação, e de fermentação de um material celulósico, formulação de caldo inteiro ou composição de cultura celular, e, célula hospedeira microbiana transgênica |
| AU2013207165B2 (en) | 2012-01-05 | 2018-10-04 | Glykos Finland Oy | Protease deficient filamentous fungal cells and methods of use thereof |
| CN104379734B (zh) | 2012-05-18 | 2018-05-15 | 诺维信公司 | 具有改进的转化效率的细菌突变体 |
| SI2852615T1 (sl) | 2012-05-22 | 2019-02-28 | Bristol-Myers Squibb Company | IL-17A/F IL-23 bispecifična protitelesa in njihova uporaba |
| US9598698B2 (en) | 2012-08-17 | 2017-03-21 | Novozymes A/S | Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof |
| WO2014068010A1 (en) | 2012-10-31 | 2014-05-08 | Novozymes A/S | Isopropanol production by bacterial hosts |
| WO2014076232A2 (en) | 2012-11-19 | 2014-05-22 | Novozymes A/S | Isopropanol production by recombinant hosts using an hmg-coa intermediate |
| WO2014100612A1 (en) * | 2012-12-21 | 2014-06-26 | Novozymes, Inc. | Methods for producing heterologous polypeptides in mutants of trichoderma |
| WO2015033356A1 (en) * | 2013-09-06 | 2015-03-12 | Council Of Scientific & Industrial Research | Enzyme composition and process of preperation theroff |
| US20170166939A1 (en) | 2013-11-26 | 2017-06-15 | Novozymes A/S | Enzyme Compositions and Uses Thereof |
| MY182924A (en) | 2014-06-06 | 2021-02-05 | Novozymes As | Enzyme compositions and uses thereof |
| DK3268482T3 (da) | 2015-03-09 | 2020-03-09 | Novozymes As | Fremgangsmåder til indføring af en flerhed af ekspressionskonstruktioner i en eukaryot celle |
| CN106566870A (zh) * | 2016-08-31 | 2017-04-19 | 泰山医学院 | 一种高通量快速筛选真菌拮抗细菌的方法 |
| CN120040562A (zh) | 2018-11-28 | 2025-05-27 | 诺维信公司 | 改善的丝状真菌宿主细胞 |
| EP3894565A1 (en) | 2018-12-12 | 2021-10-20 | Novozymes A/S | Methods for increasing the productivity of a filamentous fungal cell in the production of a polypeptide |
| EP4093188A1 (en) | 2020-01-24 | 2022-11-30 | Novozymes A/S | Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide |
| CN111909929B (zh) * | 2020-08-13 | 2022-09-27 | 中国农业科学院北京畜牧兽医研究所 | 一种靶向获取里氏木霉纤维素酶调控基因的方法 |
| US20250320512A1 (en) | 2021-12-01 | 2025-10-16 | Danisco Us Inc. | Compositions and methods for enhanced protein production in fungal cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9710475D0 (en) | 1997-05-21 | 1997-07-16 | Zeneca Ltd | Gene silencing |
| US20050229272A1 (en) * | 1999-12-30 | 2005-10-13 | Monica Driscoll | Compositions and methods for gene silencing |
| WO2003050288A1 (en) * | 2001-12-12 | 2003-06-19 | Plant Bioscience Limited | Methods and means for gene silencing in plants |
| CN1176937C (zh) * | 2003-02-21 | 2004-11-24 | 复旦大学附属中山医院 | 一种双链rna及其用途 |
| JP4789208B2 (ja) * | 2003-04-09 | 2011-10-12 | バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド | タンパク質発現に向けられた渦巻型組成物 |
| WO2005026356A1 (en) * | 2003-09-12 | 2005-03-24 | Commonwealth Scientific And Industrial Research Organisation | Modified gene-silencing nucleic acid molecules and uses thereof |
| WO2005056772A1 (en) * | 2003-12-09 | 2005-06-23 | Novozymes Inc. | Methods for eliminating or reducing the expression of genes in filamentous fungal strains |
-
2004
- 2004-12-09 WO PCT/US2004/041510 patent/WO2005056772A1/en not_active Ceased
- 2004-12-09 CN CN201110048625.1A patent/CN102174581B/zh not_active Expired - Fee Related
- 2004-12-09 US US11/009,890 patent/US8716023B2/en not_active Expired - Fee Related
- 2004-12-09 DK DK04813775.6T patent/DK1702059T3/da active
- 2004-12-09 CN CN200480041520.1A patent/CN1914311B/zh not_active Expired - Fee Related
- 2004-12-09 EP EP04813775A patent/EP1702059B1/en not_active Expired - Lifetime
- 2004-12-09 JP JP2006544043A patent/JP4842834B2/ja not_active Expired - Fee Related
-
2014
- 2014-04-17 US US14/255,642 patent/US20140287475A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1914311A (zh) | 2007-02-14 |
| CN102174581A (zh) | 2011-09-07 |
| EP1702059A1 (en) | 2006-09-20 |
| JP4842834B2 (ja) | 2011-12-21 |
| US8716023B2 (en) | 2014-05-06 |
| US20140287475A1 (en) | 2014-09-25 |
| WO2005056772A1 (en) | 2005-06-23 |
| JP2007513632A (ja) | 2007-05-31 |
| US20050158844A1 (en) | 2005-07-21 |
| EP1702059B1 (en) | 2012-11-14 |
| CN1914311B (zh) | 2011-05-04 |
| CN102174581B (zh) | 2013-04-17 |
| EP1702059A4 (en) | 2007-02-28 |
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