|
US7517884B2
(en)
|
1998-03-30 |
2009-04-14 |
Kalypsys Inc. |
Sulfonyl-substituted bicyclic compounds as modulators of PPAR
|
|
TWI263497B
(en)
*
|
2002-03-29 |
2006-10-11 |
Lilly Co Eli |
Pyridinoylpiperidines as 5-HT1F agonists
|
|
TW200526626A
(en)
|
2003-09-13 |
2005-08-16 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0325956D0
(en)
*
|
2003-11-06 |
2003-12-10 |
Addex Pharmaceuticals Sa |
Novel compounds
|
|
US7745630B2
(en)
*
|
2003-12-22 |
2010-06-29 |
Justin Stephen Bryans |
Triazolyl piperidine arginine vasopressin receptor modulators
|
|
CN1898235A
(zh)
*
|
2003-12-24 |
2007-01-17 |
普罗西迪恩有限公司 |
作为gpcr受体激动剂的杂环衍生物
|
|
NZ548693A
(en)
*
|
2004-02-18 |
2010-05-28 |
Astrazeneca Ab |
Polyheterocyclic compounds and their use as metabotropic glutamate receptor antagonists
|
|
US7269708B2
(en)
*
|
2004-04-20 |
2007-09-11 |
Rambus Inc. |
Memory controller for non-homogenous memory system
|
|
CA2570637A1
(en)
|
2004-06-24 |
2006-02-02 |
Wenqing Yao |
N-substituted piperidines and their use as pharmaceuticals
|
|
CN101080226A
(zh)
*
|
2004-08-10 |
2007-11-28 |
因塞特公司 |
酰氨基化合物及它们作为药物的用途
|
|
TW200626138A
(en)
|
2004-09-20 |
2006-08-01 |
Xenon Pharmaceuticals Inc |
Heterocyclic derivatives and their use as therapeutic agents
|
|
US8071603B2
(en)
|
2004-09-20 |
2011-12-06 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
|
|
BRPI0515482A
(pt)
|
2004-09-20 |
2008-07-22 |
Xenon Pharmaceuticals Inc |
derivados heterocìclicos e seus usos como agentes terapêuticos
|
|
MX2007003327A
(es)
|
2004-09-20 |
2007-06-05 |
Xenon Pharmaceuticals Inc |
Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
|
|
CA2580855A1
(en)
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
WO2006034341A2
(en)
|
2004-09-20 |
2006-03-30 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
|
|
TW200630337A
(en)
|
2004-10-14 |
2006-09-01 |
Euro Celtique Sa |
Piperidinyl compounds and the use thereof
|
|
HUE039584T2
(hu)
|
2004-10-29 |
2019-01-28 |
Kalypsys Inc |
PPAR-modulátor szulfonil-szubsztituált biciklusos vegyületek
|
|
EP2607362B1
(en)
*
|
2005-02-17 |
2014-12-31 |
Astellas Pharma Inc. |
Piperidine and piperazine carboxylates as FAAH inhibitors
|
|
EP1853586B1
(en)
|
2005-02-18 |
2013-07-24 |
AstraZeneca AB |
Antibacterial piperidine derivatives
|
|
GB0508319D0
(en)
|
2005-04-25 |
2005-06-01 |
Novartis Ag |
Organic compounds
|
|
GB0510139D0
(en)
*
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds B1
|
|
KR20080027463A
(ko)
*
|
2005-05-18 |
2008-03-27 |
아덱스 파마 에스에이 |
대사성 글루타메이트 수용체의 양성 알로스테릭조절자로서의 치환된 옥사디아졸 유도체
|
|
GB0510140D0
(en)
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds B2
|
|
GB0510141D0
(en)
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds B3
|
|
GB0510142D0
(en)
*
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds A1
|
|
US8541457B2
(en)
|
2005-06-03 |
2013-09-24 |
Xenon Pharmaceuticals Inc. |
Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
|
|
US20090221644A1
(en)
*
|
2005-06-30 |
2009-09-03 |
Stuart Edward Bradley |
Gpcr Agonists
|
|
JP5114395B2
(ja)
*
|
2005-06-30 |
2013-01-09 |
プロシディオン・リミテッド |
Gpcrアゴニスト
|
|
IL169855A
(en)
*
|
2005-07-25 |
2014-05-28 |
Elta Systems Ltd |
A system and method for locating a receiver location
|
|
CA2616377C
(en)
|
2005-07-26 |
2014-04-01 |
David Alexander Learmonth |
Nitrocatechol derivatives as comt inhibitors
|
|
TW200800946A
(en)
*
|
2005-08-15 |
2008-01-01 |
Astrazeneca Ab |
Substituted piperazines as metabotropic glutamate receptor antagonists
|
|
HUP0500920A2
(en)
*
|
2005-10-05 |
2007-07-30 |
Richter Gedeon Nyrt |
Oxadiazole derivatives, process for their preparation and their use
|
|
HUE040020T2
(hu)
|
2005-10-25 |
2019-02-28 |
Kalypsys Inc |
PPAR modulátorok sói és eljárások metabolikus betegségek kezelésére
|
|
ES2778846T3
(es)
|
2005-11-08 |
2020-08-12 |
Vertex Pharma |
Moduladores heterocíclicos de transportadores de casete de unión a ATP
|
|
DE102005062991A1
(de)
*
|
2005-12-28 |
2007-07-05 |
Grünenthal GmbH |
Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln
|
|
DE102005062990A1
(de)
*
|
2005-12-28 |
2007-07-05 |
Grünenthal GmbH |
Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln
|
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
|
PA8713501A1
(es)
*
|
2006-02-07 |
2009-09-17 |
Wyeth Corp |
INHIBIDORES DE 11-BETA HIDROXIESTEROIDE DEHIDROGENASA - 11ßHSD1
|
|
US7951824B2
(en)
|
2006-02-17 |
2011-05-31 |
Hoffman-La Roche Inc. |
4-aryl-pyridine-2-carboxyamide derivatives
|
|
CA2646732C
(en)
|
2006-03-29 |
2015-04-28 |
F. Hoffmann-La Roche Ag |
Pyridine and pyrimidine derivatives as mglur2 antagonists
|
|
WO2007110449A1
(en)
|
2006-03-29 |
2007-10-04 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and their use
|
|
EP1845097A1
(en)
|
2006-04-10 |
2007-10-17 |
Portela & Ca., S.A. |
Oxadiazole derivatives as COMT inhibitors
|
|
WO2007118853A1
(en)
|
2006-04-13 |
2007-10-25 |
Euro-Celtique S.A. |
Benzenesulfonamide compounds and their use as blockers of calcium channels
|
|
TW200812963A
(en)
|
2006-04-13 |
2008-03-16 |
Euro Celtique Sa |
Benzenesulfonamide compounds and the use thereof
|
|
TW200811157A
(en)
|
2006-05-05 |
2008-03-01 |
Astrazeneca Ab |
mGluR5 modulators I
|
|
TW200811156A
(en)
*
|
2006-05-05 |
2008-03-01 |
Astrazeneca Ab |
mGluR5 modulators IV
|
|
US7943622B2
(en)
|
2006-06-06 |
2011-05-17 |
Cornerstone Therapeutics, Inc. |
Piperazines, pharmaceutical compositions and methods of use thereof
|
|
FR2903405B1
(fr)
*
|
2006-07-04 |
2011-09-09 |
Pasteur Institut |
Composes a effet potentialisateur de l'activite de l'ethionamide et leurs applications
|
|
AU2007288245A1
(en)
|
2006-08-24 |
2008-02-28 |
Novartis Ag |
2- (pyrazin-2-yl) -thiazole and 2- (1h-pyrazol-3-yl) -thiazole derivatives as well as related compounds as stearoyl-CoA desaturase (SCD) inhibitors for the treatment of metabolic, cardiovascular and other disorders
|
|
JP5351025B2
(ja)
|
2006-09-22 |
2013-11-27 |
ノバルティス アーゲー |
ヘテロ環式有機化合物
|
|
SI2076508T1
(sl)
|
2006-10-18 |
2011-04-29 |
Pfizer Prod Inc |
Spojine biaril eter sečnine
|
|
GB0622202D0
(en)
*
|
2006-11-07 |
2006-12-20 |
Addex Pharmaceuticals Sa |
Novel compounds
|
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
|
MX2009006728A
(es)
|
2006-12-20 |
2009-09-09 |
Novartis Ag |
Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd.
|
|
US20080176861A1
(en)
|
2007-01-23 |
2008-07-24 |
Kalypsys, Inc. |
Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis
|
|
EP2481410B1
(en)
|
2007-01-31 |
2016-07-13 |
BIAL - Portela & Ca., S.A. |
Nitrocatechol derivates as COMT inhibitors administered with a specific dosage regime
|
|
US8399486B2
(en)
|
2007-04-09 |
2013-03-19 |
Purdue Pharma L.P. |
Benzenesulfonyl compounds and the use thereof
|
|
CN102863432B
(zh)
|
2007-05-09 |
2016-09-07 |
沃泰克斯药物股份有限公司 |
Cftr调节剂
|
|
EP2162136A4
(en)
*
|
2007-06-03 |
2012-02-15 |
Univ Vanderbilt |
GLUTAMATE METABOTROPIC POSITIVE RECEPTOR-BASED ALLOSTERIC-MODULATOR BENZAMIDE DERIVATIVES (MGLUR5) AND METHODS OF MAKING AND USING THEM
|
|
US8853392B2
(en)
|
2007-06-03 |
2014-10-07 |
Vanderbilt University |
Benzamide mGluR5 positive allosteric modulators and methods of making and using same
|
|
AU2008302570B2
(en)
|
2007-09-20 |
2012-05-31 |
Irm Llc |
Compounds and compositions as modulators of GPR119 activity
|
|
UA99308C2
(ru)
|
2007-09-26 |
2012-08-10 |
Маунт Синай Скул Оф Медсин |
Аналог азацитидина и его применение
|
|
US8765736B2
(en)
|
2007-09-28 |
2014-07-01 |
Purdue Pharma L.P. |
Benzenesulfonamide compounds and the use thereof
|
|
EA201070451A1
(ru)
*
|
2007-10-10 |
2010-10-29 |
Такеда Фармасьютикал Компани Лимитед |
Амидные соединения
|
|
SI2207775T1
(sl)
|
2007-11-05 |
2012-05-31 |
Novartis Ag |
benzilamino karboksiacil piperidinski derivati kot inhibitorji CETP uporabni za zdravljenje bolezni kot je hiperlipidemija ali arterioskleroza
|
|
CN101878199B
(zh)
|
2007-12-03 |
2013-09-18 |
诺瓦提斯公司 |
用于治疗例如高血脂或动脉硬化疾病的作为cetp抑制剂的1,2-二取代的-4-苄基氨基-吡咯烷衍生物
|
|
KR20150063170A
(ko)
|
2007-12-07 |
2015-06-08 |
버텍스 파마슈티칼스 인코포레이티드 |
3-(6-(1-(2,2-디플루오로벤조[d][1,3]디옥솔-5-일)사이클로프로판카복스아미도)-3-메틸피리딘-2-일)벤조산의 고체 형태
|
|
WO2009076142A2
(en)
|
2007-12-07 |
2009-06-18 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids
|
|
US8487121B2
(en)
*
|
2007-12-18 |
2013-07-16 |
Glenmark Pharmaceuticals S.A. |
Chromane derivatives as TRPV3 modulators
|
|
CN101959504A
(zh)
*
|
2008-02-28 |
2011-01-26 |
比艾尔-坡特拉有限公司 |
用于难溶性药物的药物组合物
|
|
CN106432213A
(zh)
|
2008-02-28 |
2017-02-22 |
沃泰克斯药物股份有限公司 |
作为cftr调节剂的杂芳基衍生物
|
|
TW200942531A
(en)
|
2008-03-17 |
2009-10-16 |
Bial Portela & Companhia S A |
Crystal forms of a nitrocatechol
|
|
UA103319C2
(en)
|
2008-05-06 |
2013-10-10 |
Глаксосмитклайн Ллк |
Thiazole- and oxazole-benzene sulfonamide compounds
|
|
CA2728405A1
(en)
*
|
2008-06-17 |
2010-01-14 |
Glenmark Pharmaceuticals, S.A. |
Chromane derivatives as trpv3 modulators
|
|
TWI434842B
(zh)
|
2008-07-14 |
2014-04-21 |
Astellas Pharma Inc |
Azole compounds
|
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
|
US8273900B2
(en)
|
2008-08-07 |
2012-09-25 |
Novartis Ag |
Organic compounds
|
|
US8609696B2
(en)
|
2008-12-18 |
2013-12-17 |
Boehringer Ingelheim International Gmbh |
Serotonin 5-HT2B receptor inhibitors
|
|
CN102264227B
(zh)
*
|
2008-12-22 |
2014-07-23 |
凯莫森特里克斯股份有限公司 |
C5aR拮抗剂
|
|
JP5705748B2
(ja)
*
|
2009-02-18 |
2015-04-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を変調する複素環化合物
|
|
WO2010098866A1
(en)
|
2009-02-27 |
2010-09-02 |
Supergen, Inc. |
Cyclopentathiophene/cyclohexathiophene dna methyltransferase inhibitors
|
|
CN105816456A
(zh)
*
|
2009-04-01 |
2016-08-03 |
巴尔-波特拉及康邦亚股份有限公司 |
包括硝基儿茶酚衍生物的药物制剂及其制备方法
|
|
KR20210009441A
(ko)
|
2009-04-01 |
2021-01-26 |
바이알 - 포르텔라 앤드 씨에이 에스에이 |
니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법
|
|
MX2011010359A
(es)
|
2009-04-02 |
2012-02-23 |
Colucid Pharmaceuticals Inc |
Composición de 2,4,6-trifluoro-n-[6-(1-metilo-piperidina-4-carboni lo)-piridina-2-ilo]-benzamida.
|
|
EP2421370A4
(en)
*
|
2009-04-23 |
2012-12-12 |
Merck Sharp & Dohme |
2-alkyl-piperidine-mGluR5 receptor MODULATORS
|
|
US8673920B2
(en)
|
2009-05-06 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
CA2764387A1
(en)
|
2009-06-05 |
2010-12-09 |
Link Medicine Corporation |
Aminopyrrolidinone derivatives and uses thereof
|
|
TW201044234A
(en)
*
|
2009-06-08 |
2010-12-16 |
Chunghwa Picture Tubes Ltd |
Method of scanning touch panel
|
|
WO2011035143A2
(en)
*
|
2009-09-17 |
2011-03-24 |
The Regents Of The University Of Michigan |
Methods and compositions for inhibiting rho-mediated diseases and conditions
|
|
US8389536B2
(en)
|
2009-10-27 |
2013-03-05 |
Hoffmann-La Roche Inc. |
Positive allosteric modulators (PAM)
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US8586581B2
(en)
|
2009-12-17 |
2013-11-19 |
Hoffmann-La Roche Inc |
Ethynyl compounds useful for treatment of CNS disorders
|
|
WO2011075699A2
(en)
|
2009-12-18 |
2011-06-23 |
Sunovion Pharmaceuticals Inc. |
Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
|
|
WO2011088015A1
(en)
|
2010-01-15 |
2011-07-21 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
US8697876B2
(en)
|
2010-04-02 |
2014-04-15 |
Colucid Pharmaceuticals, Inc. |
Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists
|
|
BR112012026255A2
(pt)
|
2010-04-07 |
2017-03-14 |
Vertex Pharma |
composições farmacêuticas de ácido 3-(6-(1-(2-,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il)benzóico e administração das mesmas
|
|
US8420661B2
(en)
|
2010-04-13 |
2013-04-16 |
Hoffmann-La Roche Inc. |
Arylethynyl derivatives
|
|
EP3159331A1
(en)
|
2010-05-05 |
2017-04-26 |
Infinity Pharmaceuticals, Inc. |
Tetrazolones as inhibitors of fatty acid synthase
|
|
WO2011140296A1
(en)
|
2010-05-05 |
2011-11-10 |
Infinity Pharmaceuticals |
Triazoles as inhibitors of fatty acid synthase
|
|
EP2575815A4
(en)
|
2010-06-04 |
2013-12-25 |
Albany Molecular Res Inc |
GLYCIN TRANSPORTER 1 INHIBITORS, METHODS OF MAKING THE SAME, AND USES THEREOF
|
|
RS56332B1
(sr)
|
2010-06-24 |
2017-12-29 |
Chemocentryx Inc |
Antagonisti c5ar
|
|
US8846936B2
(en)
|
2010-07-22 |
2014-09-30 |
Boehringer Ingelheim International Gmbh |
Sulfonyl compounds which modulate the CB2 receptor
|
|
WO2012061019A2
(en)
*
|
2010-10-25 |
2012-05-10 |
Merck Sharp & Dohme Corp. |
Tricyclic mglur5 receptor modulators
|
|
EP2632465B1
(en)
|
2010-10-27 |
2015-12-30 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US9056859B2
(en)
|
2010-10-29 |
2015-06-16 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US20140045900A1
(en)
|
2011-02-11 |
2014-02-13 |
Bial-Portela & Ca, S.A. |
Administration regime for nitrocatechols
|
|
US8772300B2
(en)
|
2011-04-19 |
2014-07-08 |
Hoffmann-La Roche Inc. |
Phenyl or pyridinyl-ethynyl derivatives
|
|
KR101576343B1
(ko)
|
2011-04-26 |
2015-12-09 |
에프. 호프만-라 로슈 아게 |
피라졸리딘-3-온 유도체
|
|
CA2829170C
(en)
|
2011-04-26 |
2019-02-26 |
F. Hoffmann-La Roche Ag |
Ethynyl derivatives as positive allosteric modulators of the mglur5
|
|
AU2012296662A1
(en)
|
2011-08-15 |
2014-03-27 |
Intermune, Inc. |
Lysophosphatidic acid receptor antagonists
|
|
ES2605164T3
(es)
|
2011-08-19 |
2017-03-13 |
Merck Sharp & Dohme Corp. |
Inhibidores del canal de potasio de la médula renal externa
|
|
US8883819B2
(en)
|
2011-09-01 |
2014-11-11 |
Irm Llc |
Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
|
|
US9527830B2
(en)
|
2011-09-16 |
2016-12-27 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US20130123254A1
(en)
|
2011-09-30 |
2013-05-16 |
Barbara Biemans |
Pharmaceutically acceptable mglur5 positive allosteric modulators and their methods of identification
|
|
WO2013052845A1
(en)
|
2011-10-05 |
2013-04-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Pi-kinase inhibitors with broad spectrum anti-infective activity
|
|
US9926309B2
(en)
|
2011-10-05 |
2018-03-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Pi-kinase inhibitors with anti-infective activity
|
|
UA110995C2
(uk)
|
2011-10-07 |
2016-03-10 |
Ф. Хоффманн-Ля Рош Аг |
Етинільні похідні як модулятори метаботропного глутаматного рецептора
|
|
UA110862C2
(uk)
|
2011-10-07 |
2016-02-25 |
Ф. Хоффманн-Ля Рош Аг |
Похідні етинілу як алостеричні модулятори метаботропного рецептора глутамату mglur 5
|
|
US8999991B2
(en)
|
2011-10-25 |
2015-04-07 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2771005B1
(en)
|
2011-10-25 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2771001A4
(en)
|
2011-10-25 |
2015-03-25 |
Merck Sharp & Dohme |
PIPERIDINYL-alkyne-orexin
|
|
US9139585B2
(en)
|
2011-10-31 |
2015-09-22 |
Merck Sharp & Dohme Corp. |
Inhibitors of the Renal Outer Medullary Potassium channel
|
|
EP2773206B1
(en)
|
2011-10-31 |
2018-02-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2013066718A2
(en)
|
2011-10-31 |
2013-05-10 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
PT2791134T
(pt)
|
2011-12-13 |
2019-12-18 |
BIAL PORTELA & Cª S A |
Composto químico útil como intermediário para a preparação de um inibidor de catecol-o-metiltransferase
|
|
US9206199B2
(en)
|
2011-12-16 |
2015-12-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EA037918B1
(ru)
|
2011-12-21 |
2021-06-07 |
Новира Терапьютикс, Инк. |
Противовирусные агенты против гепатита в
|
|
DK2806859T3
(da)
|
2012-01-25 |
2019-08-05 |
Vertex Pharma |
Formuleringer af 3-(6-(1-(2.2-difluorbenzo[d][1,3]dioxol-5-yl) cyclopropancarboxamido)-3-methylpyridin-2-yl)benzoesyre
|
|
PL2809668T3
(pl)
|
2012-02-02 |
2018-02-28 |
Idorsia Pharmaceuticals Ltd |
Związki 4-(benzimidazol-2-ilo)tiazolowowe i pokrewne aza-pochodne
|
|
PT2855453T
(pt)
|
2012-06-04 |
2017-03-09 |
Actelion Pharmaceuticals Ltd |
Derivados de benzimidazol-prolina
|
|
WO2014012851A1
(en)
|
2012-07-17 |
2014-01-23 |
F. Hoffmann-La Roche Ag |
Arylethynyl derivatives
|
|
AR092031A1
(es)
|
2012-07-26 |
2015-03-18 |
Merck Sharp & Dohme |
Inhibidores del canal de potasio medular externo renal
|
|
UA113223C2
(xx)
|
2012-08-13 |
2016-12-26 |
|
Арилетинілпіримідини
|
|
HK1208465A1
(en)
|
2012-08-28 |
2016-03-04 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
|
WO2014056710A1
(en)
|
2012-09-27 |
2014-04-17 |
F. Hoffmann-La Roche Ag |
Arylethynyl derivatives
|
|
WO2014057435A1
(en)
|
2012-10-10 |
2014-04-17 |
Actelion Pharmaceuticals Ltd |
Orexin receptor antagonists which are [ortho bi (hetero )aryl]-[2-(meta bi (hetero )aryl)-pyrrolidin-1-yl]-methanone derivatives
|
|
EP2925322B1
(en)
|
2012-11-29 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
UA115156C2
(uk)
|
2012-12-11 |
2017-09-25 |
Такеда Фармасьютікал Компані Лімітед |
Гетероциклічна сполука
|
|
US9573961B2
(en)
|
2012-12-19 |
2017-02-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2014126944A2
(en)
|
2013-02-18 |
2014-08-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
DK2961732T3
(en)
|
2013-02-28 |
2017-07-10 |
Janssen Sciences Ireland Uc |
SULFAMOYLARYLAMIDS AND USE THEREOF AS MEDICINES TO TREAT HEPATITIS B
|
|
US9073921B2
(en)
|
2013-03-01 |
2015-07-07 |
Novartis Ag |
Salt forms of bicyclic heterocyclic derivatives
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
EP2970241A1
(en)
|
2013-03-12 |
2016-01-20 |
Actelion Pharmaceuticals Ltd. |
Azetidine amide derivatives as orexin receptor antagonists
|
|
US9765074B2
(en)
|
2013-03-15 |
2017-09-19 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2014161888A1
(en)
|
2013-04-03 |
2014-10-09 |
Janssen R&D Ireland |
N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
|
EP2803668A1
(en)
|
2013-05-17 |
2014-11-19 |
Boehringer Ingelheim International Gmbh |
Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
|
|
EA030067B1
(ru)
|
2013-07-22 |
2018-06-29 |
Идорсиа Фармасьютиклз Лтд |
Производные 1-(пиперазин-1-ил)-2-([1,2,4]триазол-1-ил)этанона
|
|
ES2774749T3
(es)
|
2013-07-25 |
2020-07-22 |
Janssen Sciences Ireland Unlimited Co |
Derivados de pirrolamida sustituidos con glioxamida y su uso como medicamentos para el tratamiento de la hepatitis B
|
|
WO2015017305A1
(en)
|
2013-07-31 |
2015-02-05 |
Merck Sharp & Dohme Corp |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2015018027A1
(en)
*
|
2013-08-08 |
2015-02-12 |
Merck Sharp & Dohme Corp. |
Thiazole orexin receptor antagonists
|
|
MY192489A
(en)
|
2013-10-14 |
2022-08-23 |
Eisai R&D Man Co Ltd |
Selectively substituted quinoline compounds
|
|
EP3057948B1
(en)
|
2013-10-14 |
2018-03-14 |
Eisai R&D Management Co., Ltd. |
Selectively substituted quinoline derivatives
|
|
KR102290189B1
(ko)
|
2013-10-23 |
2021-08-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
카르복스아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
|
DK3068392T5
(da)
|
2013-11-12 |
2021-09-20 |
Vertex Pharma |
Fremgangsmåde til fremstilling af farmaceutiske sammensætninger til behandlingen af cftr-medierede sygdomme
|
|
UA116053C2
(uk)
|
2013-12-04 |
2018-01-25 |
Ідорсія Фармасьютікалз Лтд |
Застосування похідних бензоімідазолу-проліну
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
KR20160128305A
(ko)
|
2014-02-05 |
2016-11-07 |
노비라 테라퓨틱스, 인코포레이티드 |
Hbv 감염의 치료를 위한 병용 요법
|
|
DK3102572T3
(en)
|
2014-02-06 |
2019-02-04 |
Janssen Sciences Ireland Uc |
SULFAMOYLPYRROLAMIDE DERIVATIVES AND THEIR USE AS MEDICINES TO TREAT HEPATITIS B
|
|
AR099789A1
(es)
|
2014-03-24 |
2016-08-17 |
Actelion Pharmaceuticals Ltd |
Derivados de 8-(piperazin-1-il)-1,2,3,4-tetrahidro-isoquinolina
|
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
|
WO2015187541A1
(en)
|
2014-06-02 |
2015-12-10 |
Children's Medical Center Corporation |
Methods and compositions for immunomodulation
|
|
MX387238B
(es)
|
2014-09-29 |
2025-03-18 |
Chemocentryx Inc |
Procesos e compuestos intermedios en la preparación de antagonistas de c5ar.
|
|
WO2016065586A1
(en)
*
|
2014-10-30 |
2016-05-06 |
Merck Sharp & Dohme Corp. |
Pyrazole, triazole and tetrazole orexin receptor antagonists
|
|
WO2016065584A1
(en)
|
2014-10-30 |
2016-05-06 |
Merck Sharp & Dohme Corp. |
Piperidine oxadiazole and thiadiazole orexin receptor antagonists
|
|
WO2016065585A1
(en)
*
|
2014-10-30 |
2016-05-06 |
Merck Sharp & Dohme Corp. |
Piperidine isoxazole and isothiazole orexin receptor antagonists
|
|
WO2016081556A1
(en)
|
2014-11-18 |
2016-05-26 |
Vertex Pharmaceuticals Incorporated |
Process of conducting high throughput testing high performance liquid chromatography
|
|
JP2018500300A
(ja)
|
2014-11-28 |
2018-01-11 |
ノヴィファーマ,エス.アー. |
パーキンソン病を遅延させるための医薬
|
|
AR103399A1
(es)
|
2015-01-15 |
2017-05-10 |
Actelion Pharmaceuticals Ltd |
Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3
|
|
RS58349B1
(sr)
|
2015-01-15 |
2019-03-29 |
Idorsia Pharmaceuticals Ltd |
Hidroksialkil-piperazinski derivati kao modulatori cxcr3 receptora
|
|
WO2016127358A1
(en)
|
2015-02-12 |
2016-08-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of renal outer medullary potassium channel
|
|
WO2016149581A1
(en)
|
2015-03-19 |
2016-09-22 |
Novira Therapeutics, Inc. |
Azocane and azonane derivatives and methods of treating hepatitis b infections
|
|
HUE048664T2
(hu)
*
|
2015-04-24 |
2020-07-28 |
Pfizer |
1-((2R,4R)-2-(1H-benzo[D]imidazol-2-il)-l-metilpiperidin-4-il)-3-(4-cianofenil)-karbamid-maleát kristályformái
|
|
JP6603334B2
(ja)
|
2015-06-03 |
2019-11-06 |
エフ.ホフマン−ラ ロシュ アーゲー |
エチニル誘導体
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
US10196383B2
(en)
|
2015-07-17 |
2019-02-05 |
Sunshine Lake Pharma Co., Ltd. |
Substituted quinazoline compounds and preparation and uses thereof
|
|
HK1259410A1
(zh)
|
2015-09-29 |
2019-11-29 |
诺维拉治疗公司 |
乙型肝炎抗病毒剂的晶体形式
|
|
JP7339733B2
(ja)
|
2016-01-14 |
2023-09-06 |
ケモセントリックス,インコーポレイティド |
C3腎症を処置する方法
|
|
WO2017147526A1
(en)
|
2016-02-26 |
2017-08-31 |
The Board Of Trustees Of The Leland Stanford Junior University |
Pi-kinase inhibitors with anti-infective activity
|
|
EP3442524A2
(en)
|
2016-04-15 |
2019-02-20 |
Novira Therapeutics Inc. |
Combinations and methods comprising a capsid assembly inhibitor
|
|
EA202092442A3
(ru)
|
2016-06-07 |
2021-08-31 |
Джакобио Фармасьютикалс Ко., Лтд. |
Новые гетероциклические производные, применимые в качестве ингибиторов shp2
|
|
EP3375778A1
(en)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aryl-piperidine derivatives
|
|
AU2018239542C1
(en)
|
2017-03-23 |
2021-02-11 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel heterocyclic derivatives useful as SHP2 inhibitors
|
|
AU2018293752B2
(en)
*
|
2017-06-29 |
2022-09-22 |
Recordati Industria Chimica E Farmaceutica Spa |
Heterocyclylmethylidene derivatives and their use as modulators of mGluR5 receptors
|
|
WO2019014100A1
(en)
|
2017-07-10 |
2019-01-17 |
Celgene Corporation |
ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF
|
|
WO2019071073A1
(en)
|
2017-10-06 |
2019-04-11 |
Forma Therapeutics, Inc. |
INHIBITION OF THE SPECIFIC PEPTIDASE OF UBIQUITIN
|
|
WO2019160882A1
(en)
|
2018-02-13 |
2019-08-22 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
EA202092171A1
(ru)
|
2018-03-14 |
2020-12-01 |
Янссен Сайенсиз Айрлэнд Анлимитед Компани |
Схема дозирования модулятора сборки капсида
|
|
WO2019204609A1
(en)
|
2018-04-19 |
2019-10-24 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
ES2988920T3
(es)
|
2018-05-17 |
2024-11-22 |
Forma Therapeutics Inc |
Compuestos bicíclicos fusionados útiles como inhibidores de la peptidasa 30 específica de ubiquitina
|
|
BR112020026746A2
(pt)
|
2018-07-13 |
2021-03-30 |
Gilead Sciences, Inc. |
Composto, composição farmacêutica, métodos para inibir pd-1, pd-l1 e/ou a interação de pd-1/pd-l1 e para tratar câncer, e, kit para tratar ou prevenir câncer ou uma doença ou condição.
|
|
WO2020028482A1
(en)
|
2018-07-31 |
2020-02-06 |
The Trustees Of The University Of Pennsylvania |
Small molecules that sensitize hiv-1 infected cells to antibody dependent cellular cytotoxicity
|
|
TWI826514B
(zh)
|
2018-09-04 |
2023-12-21 |
美商美國禮來大藥廠 |
用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
|
|
US20210393623A1
(en)
|
2018-09-26 |
2021-12-23 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors
|
|
AU2019356011B2
(en)
|
2018-10-05 |
2025-02-06 |
Forma Therapeutics, Inc. |
Fused pyrrolines which act as Ubiquitin-Specific Protease 30 (USP30) inhibitors
|
|
TWI767148B
(zh)
|
2018-10-10 |
2022-06-11 |
美商弗瑪治療公司 |
抑制脂肪酸合成酶(fasn)
|
|
CN112955435B
(zh)
|
2018-10-24 |
2024-09-06 |
吉利德科学公司 |
Pd-1/pd-l1抑制剂
|
|
EP3886854A4
(en)
|
2018-11-30 |
2022-07-06 |
Nuvation Bio Inc. |
Pyrrole and pyrazole compounds and methods of use thereof
|
|
US20220089581A1
(en)
*
|
2019-01-25 |
2022-03-24 |
University Of Virginia Patent Foundation |
Inhibitors of spinster homolog 2 (spns2) for use in therapy
|
|
MA55020A
(fr)
|
2019-02-22 |
2021-12-29 |
Janssen Sciences Ireland Unlimited Co |
Dérivés d'amide utiles dans le traitement d'une infection par le virus de l'hépatite b ou de maladies induites par le virus de l'hépatite b
|
|
US12415788B2
(en)
|
2019-03-21 |
2025-09-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
PI4-kinase inhibitors and methods of using the same
|
|
BR112021021454A2
(pt)
|
2019-05-06 |
2021-12-21 |
Janssen Sciences Ireland Unlimited Co |
Derivados de amida úteis no tratamento da infecção por hbv ou doenças induzidas por hbv
|
|
TWI829107B
(zh)
|
2019-07-09 |
2024-01-11 |
美商美國禮來大藥廠 |
大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體,以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備
|
|
DK4069691T3
(da)
|
2019-12-06 |
2024-10-28 |
Vertex Pharma |
Substituerede tetrahydrofuraner som modulatorer af natriumkanaler
|
|
US11091447B2
(en)
|
2020-01-03 |
2021-08-17 |
Berg Llc |
UBE2K modulators and methods for their use
|
|
EP4210824A1
(en)
*
|
2020-09-09 |
2023-07-19 |
University of Virginia Patent Foundation |
Inhibitors of spinster homolog 2 (spns2) for use in therapy
|
|
WO2022069953A1
(en)
*
|
2020-09-29 |
2022-04-07 |
Ranjith Siddaraj |
Synthesis and characterization of (s)-3-(5- fluoropyridin-2-yl)-5-(piperidin-3-yl)-l,2,4-oxadiazole derivatives and their secretory phospholipase a2 (spla2) inhibitor activity
|
|
MA64853B1
(fr)
|
2021-06-04 |
2025-11-28 |
Vertex Pharmaceuticals Incorporated |
N-(hydroxyalkyl (hétéro)aryl) tétrahydrofuran carboxamides utilisés en tant que modulateurs de canaux sodiques
|
|
US20240382628A1
(en)
|
2021-07-15 |
2024-11-21 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|