JP2007504132A5 - - Google Patents

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Publication number
JP2007504132A5
JP2007504132A5 JP2006524705A JP2006524705A JP2007504132A5 JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5 JP 2006524705 A JP2006524705 A JP 2006524705A JP 2006524705 A JP2006524705 A JP 2006524705A JP 2007504132 A5 JP2007504132 A5 JP 2007504132A5
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JP
Japan
Prior art keywords
compound
daltons
molecular weight
group
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006524705A
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English (en)
Japanese (ja)
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JP2007504132A (ja
JP4848277B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/026422 external-priority patent/WO2005023834A2/en
Publication of JP2007504132A publication Critical patent/JP2007504132A/ja
Publication of JP2007504132A5 publication Critical patent/JP2007504132A5/ja
Application granted granted Critical
Publication of JP4848277B2 publication Critical patent/JP4848277B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2006524705A 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物 Expired - Lifetime JP4848277B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49874003P 2003-08-28 2003-08-28
US60/498,740 2003-08-28
PCT/US2004/026422 WO2005023834A2 (en) 2003-08-28 2004-08-13 Peptides and compounds that bind to thrombopoietin receptors

Publications (3)

Publication Number Publication Date
JP2007504132A JP2007504132A (ja) 2007-03-01
JP2007504132A5 true JP2007504132A5 (cg-RX-API-DMAC7.html) 2007-09-20
JP4848277B2 JP4848277B2 (ja) 2011-12-28

Family

ID=34272720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006524705A Expired - Lifetime JP4848277B2 (ja) 2003-08-28 2004-08-13 受容体に結合するペプチドおよび化合物

Country Status (32)

Country Link
US (1) US7576056B2 (cg-RX-API-DMAC7.html)
EP (1) EP1675606B1 (cg-RX-API-DMAC7.html)
JP (1) JP4848277B2 (cg-RX-API-DMAC7.html)
KR (2) KR20120078742A (cg-RX-API-DMAC7.html)
CN (2) CN1871022B (cg-RX-API-DMAC7.html)
AR (1) AR045530A1 (cg-RX-API-DMAC7.html)
AU (1) AU2004270656B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0414008B8 (cg-RX-API-DMAC7.html)
CA (1) CA2537421C (cg-RX-API-DMAC7.html)
CY (1) CY1118965T1 (cg-RX-API-DMAC7.html)
DK (1) DK1675606T3 (cg-RX-API-DMAC7.html)
EA (1) EA009286B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP066396A (cg-RX-API-DMAC7.html)
ES (1) ES2626107T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20170810T1 (cg-RX-API-DMAC7.html)
HU (1) HUE032370T2 (cg-RX-API-DMAC7.html)
IL (1) IL173965A (cg-RX-API-DMAC7.html)
IS (1) IS8300A (cg-RX-API-DMAC7.html)
LT (1) LT1675606T (cg-RX-API-DMAC7.html)
ME (1) ME00313B (cg-RX-API-DMAC7.html)
MX (1) MXPA06002292A (cg-RX-API-DMAC7.html)
NO (1) NO344233B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ545455A (cg-RX-API-DMAC7.html)
PL (1) PL1675606T3 (cg-RX-API-DMAC7.html)
PT (1) PT1675606T (cg-RX-API-DMAC7.html)
RS (2) RS56387B1 (cg-RX-API-DMAC7.html)
SG (1) SG131110A1 (cg-RX-API-DMAC7.html)
SI (1) SI1675606T1 (cg-RX-API-DMAC7.html)
TW (1) TWI348375B (cg-RX-API-DMAC7.html)
UA (1) UA82710C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005023834A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200602495B (cg-RX-API-DMAC7.html)

Families Citing this family (19)

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US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
EP1124961B9 (en) 1998-10-23 2010-07-21 Kirin-Amgen Inc. Thrombopoietic compounds
NZ566812A (en) 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
EA009286B1 (ru) 2003-08-28 2007-12-28 Орто-Макнейл Фармасьютикал, Инк. Пептиды и соединения, которые связываются с рецептором
US7723295B2 (en) * 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
US7615533B2 (en) 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
WO2007087428A2 (en) * 2006-01-25 2007-08-02 Amgen Inc. Thrombopoietic compounds
MY151332A (en) * 2006-02-14 2014-05-15 Janssen Pharmaceutica Nv Use of tpo peptide compounds and pharmaceutical compositions in the treatment of anemia
CA2642389C (en) * 2006-02-14 2014-05-06 Janssen Pharmaceutica N.V. Use of tpo peptide compounds and pharmaceutical compositions in the treatment of anemia
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
KR20110015448A (ko) * 2008-06-03 2011-02-15 얀센 파마슈티카 엔.브이. 암 치료와 관련된 혈액 질환을 예방하기 위한 tpo 모방 펩티드
CN103635514B (zh) 2011-06-23 2016-01-20 株式会社岛津制作所 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统
US12251424B2 (en) 2017-07-26 2025-03-18 Janssen Pharmaceutica Nv Methods of protecting vascular integrity induced by targeted radiation therapy
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
WO2020209920A2 (en) 2019-01-25 2020-10-15 Janssen Pharmaceutica Nv Methods of mitigating toxic effects of vesicants and caustic gas
EP3914272B1 (en) 2019-01-25 2024-03-06 Janssen Pharmaceutica NV Thrombopoietin mimetics for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
EP4408984A1 (en) 2021-10-01 2024-08-07 Janssen Pharmaceutica NV Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (33)

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Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
PT644771E (pt) 1992-06-11 2002-12-31 Alkermes Inc Sistema de entrega da droga eritropoietina
EP0673387B1 (en) 1992-12-11 1999-09-22 University Of Florida Materials and methods for control of pests
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
GB2285446B (en) 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
WO1995021920A1 (en) 1994-02-14 1995-08-17 Zymogenetics, Inc. Hematopoietic protein and materials and methods for making it
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
EP0723456A1 (en) 1994-02-14 1996-07-31 The University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
SG79882A1 (en) 1994-02-14 2001-04-17 Kirin Brewery Protein having tpo activity
DE69503849T2 (de) 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
CA2180021A1 (en) * 1994-11-04 1996-05-17 Yoichi Kawashima Novel 1,3-dialkylurea derivatives having a hydroxyl group
US5641655A (en) 1994-11-30 1997-06-24 Zymogenetics, Inc. Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide
AU4163196A (en) 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
JP3763846B2 (ja) 1995-04-26 2006-04-05 協和醗酵工業株式会社 新規ポリペプチド
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP1961760A3 (en) * 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
EP1223944B1 (en) 1999-09-24 2007-01-03 SmithKline Beecham Corporation Thrombopoietin mimetics
PL205949B1 (pl) * 2000-12-22 2010-06-30 Ipsen Mfg Ireland Ltd Sposób wytwarzania peptydu
WO2002078612A2 (en) 2001-04-02 2002-10-10 Euro-Celtique S.A. Thrombopoietin (tpo) synthebody for stimulation of platelet production
NZ566812A (en) * 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
EA009286B1 (ru) 2003-08-28 2007-12-28 Орто-Макнейл Фармасьютикал, Инк. Пептиды и соединения, которые связываются с рецептором

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