JP2006514931A - 化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 - Google Patents
化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 Download PDFInfo
- Publication number
- JP2006514931A JP2006514931A JP2004554400A JP2004554400A JP2006514931A JP 2006514931 A JP2006514931 A JP 2006514931A JP 2004554400 A JP2004554400 A JP 2004554400A JP 2004554400 A JP2004554400 A JP 2004554400A JP 2006514931 A JP2006514931 A JP 2006514931A
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- JP
- Japan
- Prior art keywords
- formula
- acyl
- compound
- acid
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HCUSPNBMPSRQCE-UHFFFAOYSA-N OC(c(cc(cc1)O)c1NC(c(cccc1)c1O)=O)=O Chemical compound OC(c(cc(cc1)O)c1NC(c(cccc1)c1O)=O)=O HCUSPNBMPSRQCE-UHFFFAOYSA-N 0.000 description 1
- ZRPNLHDAUCSAJI-UHFFFAOYSA-N OC(c(cc(cc1)O)c1NC(c1ccccc1)=O)=O Chemical compound OC(c(cc(cc1)O)c1NC(c1ccccc1)=O)=O ZRPNLHDAUCSAJI-UHFFFAOYSA-N 0.000 description 1
- HECLBEOHVHAGGM-UHFFFAOYSA-N OC(c(ccc(O)c1)c1NC(c1cc(O)ccc1)=O)=O Chemical compound OC(c(ccc(O)c1)c1NC(c1cc(O)ccc1)=O)=O HECLBEOHVHAGGM-UHFFFAOYSA-N 0.000 description 1
- OZOUTQJDMGSCPN-UHFFFAOYSA-N OC(c(ccc(O)c1)c1NC(c1ccccc1)=O)=O Chemical compound OC(c(ccc(O)c1)c1NC(c1ccccc1)=O)=O OZOUTQJDMGSCPN-UHFFFAOYSA-N 0.000 description 1
- QLNQAZVWZVQSBF-UHFFFAOYSA-N OC(c1cc(O)ccc1NC(c1cccc(O)c1)=O)=O Chemical compound OC(c1cc(O)ccc1NC(c1cccc(O)c1)=O)=O QLNQAZVWZVQSBF-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10254872A DE10254872A1 (de) | 2002-11-25 | 2002-11-25 | Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe |
| PCT/EP2003/012990 WO2004047833A2 (de) | 2002-11-25 | 2003-11-20 | Anthranilsäureamide und deren derivate als kosmetische und pharmazeutische wirkstoffe |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010176413A Division JP5467014B2 (ja) | 2002-11-25 | 2010-08-05 | 化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514931A true JP2006514931A (ja) | 2006-05-18 |
| JP2006514931A5 JP2006514931A5 (https=) | 2007-01-18 |
Family
ID=32240379
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004554400A Pending JP2006514931A (ja) | 2002-11-25 | 2003-11-20 | 化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 |
| JP2010176413A Expired - Lifetime JP5467014B2 (ja) | 2002-11-25 | 2010-08-05 | 化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010176413A Expired - Lifetime JP5467014B2 (ja) | 2002-11-25 | 2010-08-05 | 化粧用及び医薬用活性化合物としてのアントラニル酸アミド類及びそれらの誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8203016B2 (https=) |
| EP (1) | EP1567143B1 (https=) |
| JP (2) | JP2006514931A (https=) |
| KR (1) | KR20050085127A (https=) |
| CN (2) | CN100548289C (https=) |
| AU (1) | AU2003288126A1 (https=) |
| BR (1) | BRPI0307117B8 (https=) |
| DE (1) | DE10254872A1 (https=) |
| WO (1) | WO2004047833A2 (https=) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021518370A (ja) * | 2018-03-23 | 2021-08-02 | シムライズ アーゲー | 皮膚状態改善剤 |
| KR20220150372A (ko) * | 2020-03-06 | 2022-11-10 | 시므라이즈 아게 | 개선된 피부 침투성을 갖는 아베난쓰라마이드를 함유하는 조성물 |
| JP2023516451A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | アベナンスラミドlの化粧品または医薬品としての使用 |
| JP2023516453A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | 改善された安定性を有するアベナンスラミドまたはその類似体を含む組成物 |
| JP2023516452A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | アベナンスラミドおよびβ-グルカンを含む組成物またはエンバク抽出物 |
Families Citing this family (165)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060100274A1 (en) * | 2004-11-05 | 2006-05-11 | Trustees Of Tufts College | Therapeutic avenanthramide compounds |
| SE0400234D0 (sv) | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New compounds, methods for their preparation and use thereof |
| ITMI20050674A1 (it) * | 2005-04-15 | 2006-10-16 | Univ Degli Studi Milano | Uso di derivati ammidici come agenti modificatori del gusto composizioni aromatizzanti e prodotti che li contengono |
| WO2006134013A1 (en) * | 2005-06-14 | 2006-12-21 | Symrise Gmbh & Co. Kg | Mixtures comprising anthranilic acid amides and cooling agents as cosmetic and pharmaceutical compositions for alleviating itching |
| US20070059268A1 (en) * | 2005-09-09 | 2007-03-15 | Laura Magee | Compositions, methods and kits for treating allergic dermatitis of skin |
| US20070059679A1 (en) * | 2005-09-09 | 2007-03-15 | Michelle Garay | Method for demonstrating efficacy of a topically applied active ingredient |
| US20070059390A1 (en) * | 2005-09-09 | 2007-03-15 | Laura Magee | Compositions for inhibiting or reducing inflammation of skin |
| US20070185038A1 (en) * | 2005-09-30 | 2007-08-09 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using skin care actives |
| EP1959915B1 (en) | 2005-11-30 | 2015-05-13 | Symrise AG | Mixtures comprising anthranilic acid amides and antidandruff agents as cosmetic and pharmaceutical compositions for alleviating itching |
| EP1886662B1 (de) | 2006-06-14 | 2014-04-09 | Symrise AG | Antimikrobiell wirksame Verbindungen zur Behandlung von Mundgeruch |
| ES2462925T3 (es) * | 2006-06-14 | 2014-05-26 | Symrise Ag | Compuestos con efecto antimicrobiano para el tratamiento de fetidez oral |
| MX352516B (es) | 2006-07-05 | 2017-04-06 | Fibrotech Therapeutics Pty Ltd | Compuestos terapeuticos. |
| JP5349332B2 (ja) * | 2007-02-06 | 2013-11-20 | チェルシー・セラピューティクス,インコーポレイテッド | 新規化合物、その調製方法、およびその使用 |
| EP2455134B1 (en) | 2007-04-19 | 2016-05-11 | Mary Kay, Inc. | Magnolia extract containing compositions |
| WO2008131481A1 (en) * | 2007-04-26 | 2008-11-06 | Fibrotech Therapeutics Pty Ltd | Treatment of mesangioproliferative diseases |
| US20100267662A1 (en) * | 2007-11-08 | 2010-10-21 | Ceapro, Inc. | Avenanthramide-containing compositions |
| CA2709937C (en) * | 2007-12-21 | 2016-03-22 | Fibrotech Therapeutics Pty Ltd | Halogenated analogues of anti-fibrotic agents |
| JP4979655B2 (ja) * | 2008-08-07 | 2012-07-18 | キヤノン株式会社 | 画像符号化装置及びその制御方法 |
| US9533479B2 (en) | 2008-09-18 | 2017-01-03 | Medline Industries, Inc. | Absorbent articles having antimicrobial properties and methods of manufacturing the same |
| EP2168570B1 (en) | 2008-09-30 | 2013-12-25 | Symrise AG | Extracts of isochrysis sp. |
| EP2193785B1 (en) | 2008-12-05 | 2018-07-18 | Symrise AG | Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes |
| US20100160351A1 (en) * | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Pharmaceutical compositions and methods for treating hyperuricemia and related disorders |
| WO2010071865A1 (en) | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Pharmaceutical compositions and methods for treating hyperuricemia and related disorders |
| EP2416766B1 (en) | 2009-04-09 | 2014-04-09 | Symrise AG | Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent |
| BRPI0924661B1 (pt) | 2009-04-28 | 2018-12-11 | Symrise Ag | Ômega-ciclo-hexilalcan-1-óis, seus métodos de produção, suas composições, suas formulações cosméticas, uso dos mesmos como ativos microbianos e método parareduzir a taxa de crescimento de corynebacterium xerosis e/ou staphylococcus epidermidis e/ou brevibacterium epidermidis |
| FR2945213B1 (fr) * | 2009-05-07 | 2015-10-16 | Rocher Yves Biolog Vegetale | Compositions cosmetiques et dermatologiques et dermatologiques a base d'extrait de silene. |
| US9717818B2 (en) | 2009-05-08 | 2017-08-01 | Medline Industries, Inc. | Absorbent articles having antimicrobial properties and methods of manufacturing the same |
| EP2295031B1 (de) | 2009-08-05 | 2018-01-10 | Symrise AG | Verwendung von Pterocarpanen als Anti-Cellulite-Wirkstoffe |
| EP2174645B1 (de) | 2009-10-19 | 2015-07-29 | Symrise AG | Riechstoffhaltige Zusammensetzungen umfassend Cetylnonanoat und/oder Stearylnonanoat |
| ATE537244T1 (de) * | 2009-10-19 | 2011-12-15 | Symrise Ag | Riechstoffmischungen enthaltend isolongifolanol und moschus |
| CN102574843B (zh) | 2009-10-22 | 2015-06-17 | 法博太科制药有限公司 | 抗纤维化剂的稠环类似物 |
| EP2158896A3 (de) | 2009-11-02 | 2010-09-29 | Symrise GmbH & Co. KG | Riechstoffhaltige Zusammensetzungen umfassend Neopentylglycoldiisononanoat |
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| JP2021518370A (ja) * | 2018-03-23 | 2021-08-02 | シムライズ アーゲー | 皮膚状態改善剤 |
| KR20220150372A (ko) * | 2020-03-06 | 2022-11-10 | 시므라이즈 아게 | 개선된 피부 침투성을 갖는 아베난쓰라마이드를 함유하는 조성물 |
| JP2023516451A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | アベナンスラミドlの化粧品または医薬品としての使用 |
| JP2023516453A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | 改善された安定性を有するアベナンスラミドまたはその類似体を含む組成物 |
| JP2023516452A (ja) * | 2020-03-06 | 2023-04-19 | シムライズ アーゲー | アベナンスラミドおよびβ-グルカンを含む組成物またはエンバク抽出物 |
| JP2023517314A (ja) * | 2020-03-06 | 2023-04-25 | シムライズ アーゲー | 改善された皮膚浸透性を有する、アベナンスラミドを含む組成物 |
| JP2025004109A (ja) * | 2020-03-06 | 2025-01-14 | シムライズ アーゲー | 改善された皮膚浸透性を有する、アベナンスラミドを含む組成物 |
| JP7652789B2 (ja) | 2020-03-06 | 2025-03-27 | シムライズ アーゲー | アベナンスラミドおよびβ-グルカンを含む組成物またはエンバク抽出物 |
| KR102907648B1 (ko) * | 2020-03-06 | 2026-01-02 | 시므라이즈 아게 | 개선된 피부 침투성을 갖는 아베난쓰라마이드를 함유하는 조성물 |
| US12564551B2 (en) | 2020-03-06 | 2026-03-03 | Symrise Ag | Composition or oat extract comprising avenanthramide and β-glucan |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120315233A1 (en) | 2012-12-13 |
| WO2004047833A2 (de) | 2004-06-10 |
| DE10254872A1 (de) | 2004-06-03 |
| CN100548289C (zh) | 2009-10-14 |
| US8409552B2 (en) | 2013-04-02 |
| BRPI0307117B1 (pt) | 2017-07-18 |
| AU2003288126A1 (en) | 2004-06-18 |
| CN101683310A (zh) | 2010-03-31 |
| EP1567143A2 (de) | 2005-08-31 |
| BR0307117A (pt) | 2004-12-28 |
| CN101683310B (zh) | 2012-12-12 |
| KR20050085127A (ko) | 2005-08-29 |
| WO2004047833A3 (de) | 2005-01-13 |
| JP5467014B2 (ja) | 2014-04-09 |
| JP2010248268A (ja) | 2010-11-04 |
| US20060089413A1 (en) | 2006-04-27 |
| BRPI0307117B8 (pt) | 2021-05-25 |
| CN1713904A (zh) | 2005-12-28 |
| US8203016B2 (en) | 2012-06-19 |
| EP1567143B1 (de) | 2013-08-14 |
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