CN100548289C - 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物 - Google Patents

作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物 Download PDF

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Publication number
CN100548289C
CN100548289C CNB2003801040167A CN200380104016A CN100548289C CN 100548289 C CN100548289 C CN 100548289C CN B2003801040167 A CNB2003801040167 A CN B2003801040167A CN 200380104016 A CN200380104016 A CN 200380104016A CN 100548289 C CN100548289 C CN 100548289C
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CN
China
Prior art keywords
purposes
acyloxy
chemical compound
acid
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB2003801040167A
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English (en)
Chinese (zh)
Other versions
CN1713904A (zh
Inventor
格哈德·施毛斯
霍尔格·若佩
马丁纳·赫尔曼
克里斯托弗·萨巴泰-伦特泽尔
托拜厄斯·福辛
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Symrise AG
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Symrise AG
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Application filed by Symrise AG filed Critical Symrise AG
Publication of CN1713904A publication Critical patent/CN1713904A/zh
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
CNB2003801040167A 2002-11-25 2003-11-20 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物 Expired - Lifetime CN100548289C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10254872A DE10254872A1 (de) 2002-11-25 2002-11-25 Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe
DE10254872.2 2002-11-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN200910173877XA Division CN101683310B (zh) 2002-11-25 2003-11-20 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物

Publications (2)

Publication Number Publication Date
CN1713904A CN1713904A (zh) 2005-12-28
CN100548289C true CN100548289C (zh) 2009-10-14

Family

ID=32240379

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB2003801040167A Expired - Lifetime CN100548289C (zh) 2002-11-25 2003-11-20 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物
CN200910173877XA Expired - Lifetime CN101683310B (zh) 2002-11-25 2003-11-20 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200910173877XA Expired - Lifetime CN101683310B (zh) 2002-11-25 2003-11-20 作为化妆品和药物活性化合物的邻氨基苯甲酰胺及其衍生物

Country Status (9)

Country Link
US (2) US8203016B2 (https=)
EP (1) EP1567143B1 (https=)
JP (2) JP2006514931A (https=)
KR (1) KR20050085127A (https=)
CN (2) CN100548289C (https=)
AU (1) AU2003288126A1 (https=)
BR (1) BRPI0307117B8 (https=)
DE (1) DE10254872A1 (https=)
WO (1) WO2004047833A2 (https=)

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US8409552B2 (en) 2013-04-02
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CN101683310B (zh) 2012-12-12
KR20050085127A (ko) 2005-08-29
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US20060089413A1 (en) 2006-04-27
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Conclusion of examination: Declare the invention patent rights of claims 1-3,5-6,8 invalid, citing claims 9-12 of the aforementioned claims. The technical solutions of compound 2, compound 9, compound 10, compound 33, compound 44-45, compound 47, compound 54-55, compound 58-59, compound 60, compound 61, compound 64, and compound 65 in claim 4 are cited, and claims 9-12 of the aforementioned technical solutions in claim 4 are cited, Claim 7 relates to the technical solution of compound 2, and claims 9-12 of the aforementioned technical solution in claim 7 are cited. Claim 13 relates to the technical solutions of compounds 44-45, compound 47, compound 54-55, compound 58-59, compound 60, compound 61, compound 64, and compound 65, and the invention patent right is invalid. Claim 4 relates to the technical solution of compounds 3-8, 11-13, 30-32, 36-43, 46, 48-53, 56, 57, 62, and 63, while Claim 7 relates to the technical solution of compounds 3-7, directly or indirectly referencing the aforementioned compounds 3-...

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Denomination of invention: O-aminobenzamide and its derivatives as active compounds in cosmetics and pharmaceuticals

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