JP2006502185A5 - - Google Patents

Download PDF

Info

Publication number
JP2006502185A5
JP2006502185A5 JP2004537767A JP2004537767A JP2006502185A5 JP 2006502185 A5 JP2006502185 A5 JP 2006502185A5 JP 2004537767 A JP2004537767 A JP 2004537767A JP 2004537767 A JP2004537767 A JP 2004537767A JP 2006502185 A5 JP2006502185 A5 JP 2006502185A5
Authority
JP
Japan
Prior art keywords
composition
vitamin
composition according
concentration
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004537767A
Other languages
English (en)
Japanese (ja)
Other versions
JP5137293B2 (ja
JP2006502185A (ja
Filing date
Publication date
Priority claimed from US10/247,765 external-priority patent/US7148211B2/en
Application filed filed Critical
Publication of JP2006502185A publication Critical patent/JP2006502185A/ja
Publication of JP2006502185A5 publication Critical patent/JP2006502185A5/ja
Application granted granted Critical
Publication of JP5137293B2 publication Critical patent/JP5137293B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2004537767A 2002-09-18 2003-09-10 親油性の薬剤のための組成物 Expired - Fee Related JP5137293B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/247,765 2002-09-18
US10/247,765 US7148211B2 (en) 2002-09-18 2002-09-18 Formulation for lipophilic agents
PCT/US2003/028499 WO2004026231A2 (en) 2002-09-18 2003-09-10 Formulation for lipophilic agents

Publications (3)

Publication Number Publication Date
JP2006502185A JP2006502185A (ja) 2006-01-19
JP2006502185A5 true JP2006502185A5 (cg-RX-API-DMAC7.html) 2006-10-26
JP5137293B2 JP5137293B2 (ja) 2013-02-06

Family

ID=31992558

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004537767A Expired - Fee Related JP5137293B2 (ja) 2002-09-18 2003-09-10 親油性の薬剤のための組成物

Country Status (11)

Country Link
US (4) US7148211B2 (cg-RX-API-DMAC7.html)
EP (1) EP1553956A4 (cg-RX-API-DMAC7.html)
JP (1) JP5137293B2 (cg-RX-API-DMAC7.html)
KR (1) KR101089049B1 (cg-RX-API-DMAC7.html)
CN (1) CN100349573C (cg-RX-API-DMAC7.html)
AU (1) AU2003267131B2 (cg-RX-API-DMAC7.html)
BR (1) BR0314354A (cg-RX-API-DMAC7.html)
CA (1) CA2498331A1 (cg-RX-API-DMAC7.html)
IL (1) IL167309A (cg-RX-API-DMAC7.html)
MX (1) MXPA05002814A (cg-RX-API-DMAC7.html)
WO (1) WO2004026231A2 (cg-RX-API-DMAC7.html)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263580B2 (en) 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
AU2002363959B2 (en) * 2001-12-03 2007-12-13 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
US20050175697A1 (en) * 2003-12-29 2005-08-11 David Edgren Novel drug compositions and dosage forms of topiramate
US20050175690A1 (en) * 2003-12-29 2005-08-11 David Edgren Novel drug compositions and dosage forms
EP1534238A1 (en) * 2002-07-29 2005-06-01 ALZA Corporation Formulations and dosage forms for controlled delivery of topiramate
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20050026877A1 (en) * 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
AU2004264316A1 (en) * 2003-08-06 2005-02-24 Alza Corporation Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation
AU2003282780A1 (en) 2003-08-08 2005-03-07 Abgenix, Inc. Antibodies directed to parathyroid hormone (pth) and uses thereof
US7318925B2 (en) 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
GB2413282B (en) * 2004-04-23 2009-01-14 Henderson Morley Plc DNA Viral Infections
US20060222700A1 (en) * 2005-04-05 2006-10-05 Groenewoud Pieter J Tablet and capsule form of liquid active ingredient
AU2006236564B2 (en) * 2005-04-15 2011-02-17 Besins Healthcare Luxembourg S.A.R.L. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US20070026026A1 (en) * 2005-08-01 2007-02-01 David Delmarre Oral liquid losartan compositions
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CA2647533A1 (en) * 2006-03-28 2007-10-04 Javelin Pharmaceuticals, Inc. Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
US8580954B2 (en) 2006-03-28 2013-11-12 Hospira, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
US8900619B2 (en) 2006-08-24 2014-12-02 Boston Scientific Scimed, Inc. Medical devices for the release of therapeutic agents
AU2008241470B2 (en) 2007-04-16 2013-11-07 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
WO2009002425A2 (en) * 2007-06-22 2008-12-31 Scidose Llc Solubilized formulation of docetaxel without tween 80
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
AU2008321396A1 (en) 2007-11-13 2009-05-22 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
JP5623288B2 (ja) 2007-12-21 2014-11-12 エイオーピーオーファン ファーマスーティカルズ アクチエンゲゼルシャフトＡＯＰ Ｏｒｐｈａｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 医薬組成物
DE102008004694A1 (de) * 2008-01-16 2009-07-23 Gesellschaft für medizinische Forschung und Weiterbildung e.V. (GMF) Benzodiazepin und/oder Benzodiazepinderivate enthaltende pharmazeutische Zusammensetzung
US20090253712A1 (en) * 2008-04-03 2009-10-08 Semmelweis Egyetem Aqueous solvent system for solubilization of azole compounds
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
CN103251631A (zh) * 2008-05-13 2013-08-21 根梅迪卡治疗公司 用于治疗代谢性病症的水杨酸盐(酯)缀合物
US20100075933A1 (en) * 2008-07-28 2010-03-25 Sunita Vijay Shelke Injectable compositions of vitamin d compounds
CA2732412C (en) * 2008-07-30 2014-12-09 Lei Yu Retinoid-targeted drug carriers
US20120277629A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collection and/or manipulation of blood spots or other bodily fluids
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
WO2010101620A2 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin
BRPI1011593A2 (pt) * 2009-03-16 2016-03-22 Genmedica Therapeutics Sl "combinação farmacêutica, composição farmaceuticamente aceitavél, e, método para tratar um distúrbio metabólico, para tratar doença pulmonar obstrutiva crônica, e para tratar ou prevenir um ou mais distúrbios metabólicos."
AU2010224866C1 (en) * 2009-03-16 2015-01-15 Genmedica Therapeutics Sl Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
DE102009018133A1 (de) * 2009-04-15 2010-11-11 Agon Pharma Gmbh Pharmazeutische Zusammensetzung zur Behandlung von dermatologischen Autoimmunerkrankungen
US20100297262A1 (en) * 2009-04-17 2010-11-25 Colby Pharmaceutical Company Pharmaceutically active compositions comprising oxidative stress modulators (osm), new chemical entities, compositions and uses
CA2765033C (en) * 2009-06-12 2020-07-14 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US8563574B2 (en) 2009-12-07 2013-10-22 Academic Pharmaceuticals, Inc. Parenteral formulation of clopidogrel
EP2377556A1 (de) * 2010-04-14 2011-10-19 Cognis IP Management GmbH Eine Zusammensetzung
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2637562B1 (en) 2010-11-09 2016-01-27 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
US8466197B2 (en) 2010-12-14 2013-06-18 Genmedica Therapeutics Sl Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders
CA2823628A1 (en) 2011-01-05 2012-07-12 Hospira, Inc. Spray drying vancomycin
PT2685979T (pt) 2011-03-18 2016-12-02 Alkermes Pharma Ireland Ltd Composições farmacêuticas injetáveis compreendendo um antipsicótico solúvel em água, laurato de sorbitano e polissorbato 20
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
US20130158468A1 (en) * 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
CN102178642A (zh) * 2011-04-29 2011-09-14 苏州大学 一种替米沙坦固体分散体及其制备方法
EP2545940A1 (de) * 2011-07-14 2013-01-16 hameln rds gmbh Parenterale Zusammensetzungen
US8513278B2 (en) 2011-11-26 2013-08-20 Academic Pharmaceuticals, Inc. Parenteral dextrose formulation of clopidogrel
CA2867121C (en) 2012-03-19 2021-05-25 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
JP6219918B2 (ja) 2012-03-19 2017-10-25 アルカームス ファーマ アイルランド リミテッド グリセロールエステルを含む医薬組成物
AU2013235526B2 (en) 2012-03-19 2017-11-30 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising benzyl alcohol
US9193685B2 (en) 2012-09-19 2015-11-24 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
KR102265808B1 (ko) 2012-12-21 2021-06-16 코리움, 인크. 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법
US9795560B2 (en) * 2013-02-01 2017-10-24 Ocularis Pharma, Llc Aqueous ophthalmic solutions of phentolamine and medical uses thereof
EP2950800B1 (en) 2013-02-01 2020-09-09 Ocuphire Pharma, Inc. Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
JP6516720B2 (ja) 2013-03-13 2019-05-22 トリス・フアルマ・インコーポレーテツド ベンゾナテート改変放出性固体錠剤およびカプセル剤
US9180104B2 (en) 2013-03-13 2015-11-10 Tris Pharma, Inc. Benzonatate modified release solid tablets and capsules
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
EP2968116A1 (en) 2013-03-15 2016-01-20 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CN105246458B (zh) 2013-03-15 2020-09-15 考里安公司 用于治疗剂递送的微阵列及其使用方法
CA2938626A1 (en) 2013-07-26 2015-01-29 John Rothman Compositions to improve the therapeutic benefit of bisantrene
CN105813480A (zh) * 2013-12-11 2016-07-27 帝斯曼知识产权资产管理有限公司 一种营养强化组合物及其制备方法
WO2015143145A1 (en) 2014-03-20 2015-09-24 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
CN104162168B (zh) * 2014-08-07 2019-07-02 北京泰德制药股份有限公司 一种稳定的帕立骨化醇药物组合物及其制备方法
EP3188714A1 (en) * 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN105055373A (zh) * 2015-08-19 2015-11-18 西安岳达植物科技有限公司 一种包埋叶黄素酯的制备
CN107184566B (zh) * 2017-05-19 2020-04-24 澳门大学 含有叶黄素的药物组合物及其制备方法和制剂
EP3761983A1 (en) 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
US12161629B2 (en) 2018-10-15 2024-12-10 Opus Genetics, Inc. Methods and compositions for treatment of glaucoma and related conditions
CN113164452A (zh) 2018-10-26 2021-07-23 奥库菲尔制药股份有限公司 治疗老花眼、散瞳和其他眼部疾病的方法和组合物
WO2021022058A2 (en) * 2019-08-01 2021-02-04 Incarda Therapeutics, Inc. Antiarrhythmic formulation
CN112569184A (zh) * 2020-12-30 2021-03-30 山东裕欣药业有限公司 一种盐酸替罗非班注射液及制备方法
CN115368310B (zh) 2021-05-18 2025-06-27 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法

Family Cites Families (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2383446A (en) 1941-06-04 1945-08-28 Du Pont Antirachitic materials and processes for their production
US3384545A (en) * 1965-03-09 1968-05-21 Hoffmann La Roche Injectable aqueous emulsions of fat soluble vitamins
US3697559A (en) 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
US3741996A (en) 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US5472957A (en) * 1973-01-10 1995-12-05 Research Institute For Medicine And Chemistry Chemical compounds and process
US3932634A (en) 1973-06-28 1976-01-13 Pfizer Inc. High potency vitamin water dispersible formulations
US3907843A (en) 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
DE2526938C2 (de) 1975-02-14 1982-04-22 F. Hoffmann-La Roche & Co. AG, 4002 Basel Vitaminpräparate
US4202829A (en) 1978-01-05 1980-05-13 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4195027A (en) 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4260549A (en) 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
NL188286C (nl) 1978-01-16 1992-05-18 Wisconsin Alumni Res Found Werkwijze voor het bereiden van een 1alfa-hydroxyvitamine d verbinding.
US4160803A (en) 1978-03-23 1979-07-10 Corning Glass Works Self packaged test kit
US4225596A (en) 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4335120A (en) * 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
JPS55136229A (en) 1979-04-10 1980-10-23 Teijin Ltd Adjustment of bone metabolism in warm-blooded animal and drug for it
US4234495A (en) 1979-09-10 1980-11-18 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxyvitamin D compounds from 1α-hydroxy-3,5-cyclovitamin D compounds
JPS6233Y2 (cg-RX-API-DMAC7.html) 1979-11-08 1987-01-06
US4362710A (en) 1980-07-04 1982-12-07 Nissan Gosei Kogyo Co., Ltd. Feeds for baby pigs, process for preparing the same and method of breeding baby pigs
US4308264A (en) * 1981-01-28 1981-12-29 Abbott Laboratories Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration
JPS57149224A (en) 1981-03-13 1982-09-14 Chugai Pharmaceut Co Ltd Tumor-suppressing agent
US4508651A (en) 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3448412C2 (cg-RX-API-DMAC7.html) 1983-05-09 1991-12-12 Wisconsin Alumni Res Found
US4689180A (en) 1984-01-30 1987-08-25 Wisconsin Alumni Research Foundation 1α,25-dihydroxy-22Z-dehydroxyvitamin D compound
US4727064A (en) 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US4588716A (en) 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
US4555364A (en) 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
US4554106A (en) 1984-11-01 1985-11-19 Wisconsin Alumni Research Foundation Method for preparing 1α-hydroxyvitamin D compounds
US4717721A (en) 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
US4661294A (en) 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
IL78342A (en) 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
WO1987000834A1 (en) 1985-08-02 1987-02-12 Leo Pharmaceutical Products Ltd. A/S Novel vitamin d analogues
JPS62149619A (ja) * 1985-09-05 1987-07-03 Teijin Ltd 活性型ビタミンｄ３類注射用組成物
US4816247A (en) 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
US4784845A (en) 1985-09-16 1988-11-15 American Cyanamid Company Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US5554386A (en) 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
US5527524A (en) 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
US5338532A (en) 1986-08-18 1994-08-16 The Dow Chemical Company Starburst conjugates
US4833125A (en) 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass
US4823125A (en) * 1987-06-30 1989-04-18 Develco, Inc. Method and apparatus for stabilizing a communication sensor in a borehole
US4877778A (en) 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
US4902481A (en) 1987-12-11 1990-02-20 Millipore Corporation Multi-well filtration test apparatus
US5232836A (en) 1988-05-04 1993-08-03 Ire-Medgenix S.A. Vitamin D derivatives: therapeutic applications and applications to assays of metabolites of vitamin D
US5104864A (en) 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US5602116A (en) 1988-08-02 1997-02-11 Bone Care International, Inc. Method for treating and preventing secondary hyperparathyroidism
WO1990003173A1 (fr) * 1988-09-26 1990-04-05 Teijin Limited Preparation aqueuse stable a base de vitamine d3 active
JP2525478B2 (ja) 1989-03-01 1996-08-21 帝人株式会社 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤
CA1333616C (en) 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5372996A (en) 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
US4948789A (en) 1989-03-28 1990-08-14 Chugai Seiyaku Kabushiki Kaisha Suppression of parathyroid hormone synthesis and secretion
JP2645130B2 (ja) 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
GB2229921B (en) 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
US5219528A (en) 1989-07-28 1993-06-15 Pierce Chemical Company Apparatus for rapid immunoassays
US5085864A (en) 1989-10-30 1992-02-04 Abbott Laboratories Injectable formulation for lipophilic drugs
WO1993007883A1 (en) 1991-10-24 1993-04-29 Isis Pharmaceuticals, Inc. Derivatized oligonucleotides having improved uptake and other properties
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5260290A (en) 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
JP3201411B2 (ja) 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンｄ類の生物学的製造方法
US5092840A (en) 1990-07-16 1992-03-03 Healy Patrick M Valved medicine container
US5141719A (en) 1990-07-18 1992-08-25 Bio-Rad Laboratories, Inc. Multi-sample filtration plate assembly
US5120720A (en) 1990-09-20 1992-06-09 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Preparation of lipophile:hydroxypropylcyclodextrin complexes by a method using co-solubilizers
US5798345A (en) 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5763428A (en) 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
KR100231809B1 (ko) 1990-09-21 1999-12-01 로버트 에이. 벡크만 1알파-하이드록시 비타민 d4 및 이의 중간체 및 동족체, 및 이를 포함하는 약제학적 조성물
US5124152A (en) * 1991-01-07 1992-06-23 Fisons Corporation Parenteral formulation of metolazone
EP0914825B1 (en) 1991-01-08 2003-05-21 Bone Care International, Inc. Methods for preparation of 1 alpha, 24-dihydroxy vitamin D2
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US5298246A (en) 1991-01-09 1994-03-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Stable pharmaceutical composition and method for its production
DK0503630T3 (da) 1991-03-13 1996-01-29 Kuraray Co Cyclohexantriolderivater
US5264184A (en) 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
ATE144424T1 (de) 1991-04-09 1996-11-15 Takeda Chemical Industries Ltd Stabilisiertes vitamin d arzneimittel
GB9108655D0 (en) 1991-04-23 1991-06-12 Waverley Pharma Ltd Improved multi-use liquid dispensers
US5417923A (en) 1991-04-24 1995-05-23 Pfizer Inc. Assay tray assembly
AU666654B2 (en) 1991-05-28 1996-02-22 Procter & Gamble Company, The Calcium, trace mineral, vitamin D and drug therapy combinations
US5637982A (en) * 1991-06-17 1997-06-10 Kabushiki Kaisha Toshiba Method and system for detecting full charge of a rechargeable battery in a portable computer system
ES2093180T3 (es) 1991-07-05 1996-12-16 Duphar Int Res Compuesto de vitamina d, metodo de preparar este compuesto y producto intermedio de dicho metodo.
US5205989A (en) 1991-09-18 1993-04-27 Minnesota Mining And Manufacturing Company Multi-well filtration apparatus
US5360413A (en) 1991-12-06 1994-11-01 Filtertek, Inc. Needleless access device
JP2927368B2 (ja) 1992-01-29 1999-07-28 ボーン ケア インターナショナル インコーポレイテッド １α−ヒドロキシ−２４−ＥＰＩ−ビタミンＤ▲下４▼
US5323836A (en) * 1992-03-13 1994-06-28 Boise Cascade Corporation Modular portable display screen
EP0562497A1 (en) 1992-03-27 1993-09-29 Nisshin Flour Milling Co., Ltd. 1 alpha-hydroxy vitamins D7 and D4' processes for the preparation thereof and pharmaceutical compositions
US6113946A (en) 1992-04-03 2000-09-05 The Regents Of The University Of California Self-assembling polynucleotide delivery system comprising dendrimer polycations
US5795882A (en) 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
ES2170069T3 (es) 1992-06-22 2002-08-01 Bone Care Int Inc 1-alfa-hidroxiprevitamina d para administracion oral.
IL103224A (en) 1992-09-18 1998-08-16 Teva Pharma Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
US5366965A (en) 1993-01-29 1994-11-22 Boehringer Mannheim Gmbh Regimen for treatment or prophylaxis of osteoporosis
US5350745A (en) 1993-01-29 1994-09-27 Lunar Corporation Treatment of myocardial failure
US5880114A (en) 1993-06-16 1999-03-09 Wisconsin Alumni Research Foundation Treatment of immune deficiency with vitamin D compounds
US5716346A (en) 1993-07-02 1998-02-10 Farris; Barry Method and apparatus for loading syringes without the need for hypodermic needles
IL110309A0 (en) 1993-07-15 1994-10-21 Univ Kentucky Res Found A method of protecting against neuron loss
US5763429A (en) 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
WO1995017889A1 (en) 1993-12-29 1995-07-06 Kowa Tekuno Sachi Co., Ltd. Therapeutic composition for hyperparathyroidism of patient subjected to artificial dialysis
US5549577A (en) 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
ATE168367T1 (de) 1994-01-20 1998-08-15 Duphar Int Res Vitamin-d-derivate und verfahren zu deren herstellung
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
CA2122431C (en) 1994-04-28 2006-10-10 Reinhold W. Vieth Topical administration of vitamin d to mammals and compositions therefor
US5932544A (en) * 1994-05-31 1999-08-03 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) compositions
US5597575A (en) 1994-06-06 1997-01-28 Breitbarth; Richard Composition for stimulating and inducing hair growth
AU696856B2 (en) 1994-09-01 1998-09-17 Pharmacia & Upjohn Company Cosolvent parenteral formulation of tirilazad
US5766582A (en) 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
FR2730995B1 (fr) 1995-02-23 1997-04-04 Cird Galderma Composes bi-aromatiques derives d'amide, compositions pharmaceutiques et cosmetiques les contenant et utilisations
JPH11504028A (ja) 1995-04-24 1999-04-06 イースム リサーチ ディベロップメント カンパニー オブ ザ ヒーブル ユニバーシティ オブ エルサレム 油／水エマルジョンを作り出す自己乳化性配合物
IL118156A (en) 1995-05-09 2001-08-26 Duphar Int Res Vitamin d compounds, their preparation and pharmaceutical compositions containing them
AU5861396A (en) 1995-05-19 1996-11-29 Abbott Laboratories Stable aqueous formulations of 1alpha,25-dihydroxycholecalci ferol for parenteral administration
US5739271A (en) 1995-06-07 1998-04-14 Gen-Probe Incorporated Thiocationic lipids
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5869386A (en) 1995-09-28 1999-02-09 Nec Corporation Method of fabricating a composite silicon-on-insulator substrate
ATE189812T1 (de) * 1995-10-30 2000-03-15 Hoffmann La Roche 1-alpha, 26-dihydroxy-d-homo-vitamin d3
US5691328A (en) 1996-02-02 1997-11-25 Clarion Pharmaceuticals Inc. Phosphoethanolamine conjugates of vitamin D compounds
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6046177A (en) 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US5874418A (en) 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
FR2767691B1 (fr) * 1997-08-27 2000-02-18 Oreal Utilisation d'une dispersion a base de vehicules lipidiques comme composition anti-inflammatoire
ES2368824T3 (es) 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
US6136799A (en) 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
US6294548B1 (en) 1998-05-04 2001-09-25 Hoffmann-La Roche Inc. Multidose vial formulations for administering endo-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
US5972917A (en) 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
FR2781667B1 (fr) * 1998-07-30 2001-06-01 Oreal Patch cosmetique, pharmaceutique, ou dermatologique
US6521237B2 (en) * 1998-11-12 2003-02-18 Johnson & Johnson Consumer Companies, Inc. Skin care composition
JP2002531515A (ja) 1998-12-11 2002-09-24 ファーマソリューションズ・インコーポレイテッド 水に難溶性の薬剤のための自己乳化組成物
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
WO2000040228A2 (en) 1999-01-08 2000-07-13 3M Innovative Properties Company Formulations comprising imiquimod or other immune response modifiers for treating mucosal conditions
US6020383A (en) * 1999-01-11 2000-02-01 Eastman Chemicals Company Method for reducing blood cholesterol and/or blood triglycerides
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
WO2000061112A2 (en) 1999-04-13 2000-10-19 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) Solubilized pharmaceutical composition for parenteral administration
EP1261340B1 (en) 1999-07-13 2009-05-13 Alpha Research Group, LLC Compositions and methods for the treatment of parkinson's disease
ATE304863T1 (de) 1999-07-22 2005-10-15 Aventis Pharma Inc Erythropoietin formulierungen des mehrfachdosis- typs
US6051567A (en) 1999-08-02 2000-04-18 Abbott Laboratories Low oxygen content compositions of 1α, 25-dihydroxycholecalciferol
US6211169B1 (en) 1999-09-29 2001-04-03 Aesgen, Inc. Stable calcitriol solution for packaging into vials
US6450994B1 (en) 2000-03-15 2002-09-17 Allergan, Inc. Storage and delivery of multi-dose, preservative-free pharmaceuticals
JP4825343B2 (ja) * 2000-05-29 2011-11-30 株式会社大塚製薬工場 総合ビタミン液剤およびその収容体
CA2414407A1 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. Stabilized 1.alpha.-hydroxy vitamin d
JP2002069003A (ja) 2000-08-23 2002-03-08 Teijin Ltd ビタミンｄ誘導体を含有する骨吸収抑制剤
AU2002213484A1 (en) 2000-10-20 2002-05-06 Baxter International Inc. Multi-dose container system
JP3854524B2 (ja) * 2002-04-01 2006-12-06 ピアス株式会社 油溶性成分安定化組成物及びその組成物を配合した化粧料、並びに油溶性成分の安定化方法

Similar Documents

Publication Publication Date Title
JP2006502185A5 (cg-RX-API-DMAC7.html)
Beer et al. Calcitriol in cancer treatment: from the lab to the clinic
Cipriani et al. Long-term bioavailability after a single oral or intramuscular administration of 600,000 IU of ergocalciferol or cholecalciferol: implications for treatment and prophylaxis
Christakos et al. Minireview: vitamin D: is there a role in extraskeletal health?
US8741878B2 (en) Petroleum jelly-free unguent compositions comprising vitamin D compounds and optionally steroidal anti-inflammatory agents
EP2968172B1 (en) Stabilized modified release vitamin d formulation and method of administring same
JP5137293B2 (ja) 親油性の薬剤のための組成物
CN102939078B (zh) 含有维生素d类似物和皮质类固醇的药用喷雾剂组合物
Krishnan et al. Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: importance of mammary CYP27B1 for treatment and prevention
US10363314B2 (en) Sprayable topical carrier and composition comprising phosphatidylcholine
CA2797537C (en) Use of 25-hydroxyvitamin d compound for reducing parathyroid levels
Muszkat et al. Evidence-based non-skeletal actions of vitamin D
Rossdeutscher et al. Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer
Kamangar et al. Oral vitamin D, still a viable treatment option for psoriasis
Duplancic et al. The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
JP2008534482A (ja) 局所用組成物およびその使用
EP2515866B1 (en) Pharmaceutical composition comprising solvent mixture and a vitamin d derivative or analogue
CN102770143A (zh) 包含维生素d类似物和共溶剂-表面活性剂混合物的药物组合物
Brandi et al. Calcidiol [25 (OH) D3]: from diagnostic marker to therapeutical agent
Bacchetta et al. Immune, metabolic and epidemiological aspects of vitamin D in chronic kidney disease and transplant patients
Lea et al. Calcipotriol: a review of its pharmacological properties and therapeutic efficacy in the management of psoriasis
O’Kelly et al. Vitamin D analogs and breast cancer
Filip et al. Antitumor properties of (5E, 7E) analogs of vitamin D3
KR101755407B1 (ko) 건선의 예방 또는 치료용 약제학적 조성물
Cheng et al. Paricalcitol capsules for the control of secondary hyperparathyroidism in chronic kidney disease