JP2006500394A5 - - Google Patents
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- Publication number
- JP2006500394A5 JP2006500394A5 JP2004534722A JP2004534722A JP2006500394A5 JP 2006500394 A5 JP2006500394 A5 JP 2006500394A5 JP 2004534722 A JP2004534722 A JP 2004534722A JP 2004534722 A JP2004534722 A JP 2004534722A JP 2006500394 A5 JP2006500394 A5 JP 2006500394A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- independently
- phenyl
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40872302P | 2002-09-06 | 2002-09-06 | |
| PCT/US2003/028017 WO2004022537A2 (en) | 2002-09-06 | 2003-09-05 | Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006500394A JP2006500394A (ja) | 2006-01-05 |
| JP2006500394A5 true JP2006500394A5 (https=) | 2006-10-19 |
| JP4596915B2 JP4596915B2 (ja) | 2010-12-15 |
Family
ID=31978666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004534722A Expired - Fee Related JP4596915B2 (ja) | 2002-09-06 | 2003-09-05 | チエノピロリルおよびフラノピロリル化合物並びにヒスタミンｈ４受容体リガンドとしてのそれらの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7226938B2 (https=) |
| EP (1) | EP1543011B1 (https=) |
| JP (1) | JP4596915B2 (https=) |
| AT (1) | ATE325125T1 (https=) |
| AU (1) | AU2003272285A1 (https=) |
| CA (1) | CA2497868C (https=) |
| CY (1) | CY1105080T1 (https=) |
| DE (1) | DE60305052T2 (https=) |
| DK (1) | DK1543011T3 (https=) |
| ES (1) | ES2264534T3 (https=) |
| PT (1) | PT1543011E (https=) |
| WO (1) | WO2004022537A2 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1543011B1 (en) * | 2002-09-06 | 2006-05-03 | Janssen Pharmaceutica N.V. | Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands |
| GB0222912D0 (en) * | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222909D0 (en) * | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| CA2540260A1 (en) * | 2003-09-26 | 2005-04-07 | Janssen Pharmaceutica N.V. | Analyzing histamine h4 receptor-mediated effects in whole blood |
| AU2004312530A1 (en) * | 2003-12-29 | 2005-07-21 | Sepracor Inc. | Pyrrole and pyrazole DAAO inhibitors |
| ES2315877T3 (es) | 2004-06-18 | 2009-04-01 | Biolipox Ab | Indoles utiles en el tratamiento de inflamaciones. |
| EP1776982A1 (en) * | 2005-10-18 | 2007-04-25 | Argenta Discovery Limited | Pyrimidine compounds as histamine modulators |
| EP1812113A1 (en) * | 2004-11-11 | 2007-08-01 | Argenta Discovery Limited | Pyrimidine compounds as histamine modulators |
| EP1671972A1 (en) * | 2004-11-24 | 2006-06-21 | Pfizer Limited | Octahydropyrrolo[3,4-c]pyrrole derivatives |
| JP2008520644A (ja) * | 2004-11-24 | 2008-06-19 | ファイザー・インク | オクタヒドロピロロ［３，４−ｃ］ピロール誘導体 |
| CN101142185A (zh) | 2005-01-19 | 2008-03-12 | 比奥里波克斯公司 | 用于炎症治疗的吲哚 |
| JP2009500425A (ja) | 2005-07-06 | 2009-01-08 | セプラコア インコーポレーテッド | エスゾピクロン及びトランス４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロ−ｎ−メチル−１−ナフタレンアミン又はトランス４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロ−１−ナフタレンアミンの組み合わせ、並びに閉経期並びに気分、不安、及び認知障害の治療方法 |
| EP1767537A1 (en) * | 2005-09-21 | 2007-03-28 | Cellzome (UK) Ltd. | Pyrimidine compounds for the treatment of inflammatory disorders |
| NL2000323C2 (nl) | 2005-12-20 | 2007-11-20 | Pfizer Ltd | Pyrimidine-derivaten. |
| NZ569608A (en) | 2006-01-06 | 2011-09-30 | Sepracor Inc | Tetralone-based monoamine reuptake inhibitors |
| BRPI0706365A2 (pt) | 2006-01-06 | 2011-03-22 | Sepracor Inc | Cicloalquilaminas como inibidores da recaptação de monoamina |
| PL2007752T3 (pl) | 2006-03-31 | 2011-02-28 | Janssen Pharmaceutica Nv | Benzoimidazol-2-ilopirymidyny i pirazyny jako modulatory receptora histaminowego H4 |
| DK2816024T3 (en) | 2006-03-31 | 2017-10-30 | Sunovion Pharmaceuticals Inc | CHIRALE AMINER |
| WO2007120690A2 (en) * | 2006-04-10 | 2007-10-25 | Janssen Pharmaceutica N.V. | Combination histamine h1r and h4r antagonist therapy for treating pruritus |
| US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080058395A1 (en) * | 2006-06-30 | 2008-03-06 | Sepracor Inc. | Fused heterocyclic inhibitors of D-amino acid oxidase |
| EP2057162A2 (en) * | 2006-06-30 | 2009-05-13 | Sepracor Inc. | Fused heterocyclic inhibitors of d-amino acid oxidase |
| US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
| US7985745B2 (en) | 2006-10-02 | 2011-07-26 | Abbott Laboratories | Method for pain treatment |
| US8492405B2 (en) | 2006-10-18 | 2013-07-23 | Takeda Pharmaceutical Company Limited | Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity |
| WO2008074445A1 (en) * | 2006-12-18 | 2008-06-26 | Ucb Pharma, S.A. | Novel tricyclic and heterotricyclic derivatives, processes for preparing them, pharmaceutical compositions thereof |
| US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| US20090099248A1 (en) * | 2007-01-18 | 2009-04-16 | Sepracor Inc. | Inhibitors of d-amino acid oxidase |
| AU2008259841B2 (en) | 2007-05-31 | 2015-02-05 | Sunovion Pharmaceuticals Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
| MX2010013727A (es) * | 2008-06-12 | 2011-01-14 | Janssen Pharmaceutica Nv | Uso de un antagonista h4 de histamina para el tratamiento de adherencias postoperatorias. |
| US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
| WO2010017418A1 (en) * | 2008-08-07 | 2010-02-11 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| EP2201982A1 (en) | 2008-12-24 | 2010-06-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Histamine H4 receptor antagonists for the treatment of vestibular disorders |
| WO2011013752A1 (ja) * | 2009-07-31 | 2011-02-03 | 塩野義製薬株式会社 | 縮合へテロ環誘導体を含有する医薬組成物 |
| WO2011017634A2 (en) * | 2009-08-07 | 2011-02-10 | Sepracore Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| HUE039713T2 (hu) | 2012-06-08 | 2019-02-28 | Sensorion | H4 receptor inhibitorok tinnitus kezelésére |
| SMT202000084T1 (it) | 2013-03-06 | 2020-03-13 | Janssen Pharmaceutica Nv | Modulatori benzoimidazol-2-il pirimidinici del recettore h4 dell'istamina |
| TW201729810A (zh) | 2015-10-26 | 2017-09-01 | 札爾科製藥公司 | 嘧啶組成物、其超純組成物及鹽類、製造彼之方法、及使用彼於治療組織胺h4受體(h 4 )仲介之疾病與病情之方法 |
| CN109499595B (zh) * | 2018-11-16 | 2021-10-08 | 中国林业科学研究院林产化学工业研究所 | 一种氧还原反应（orr）催化剂gpncs及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2571723B1 (fr) * | 1984-10-12 | 1988-08-26 | Lipha | Derives de thieno et furo-(2,3-c) pyrroles, procedes de preparation et medicaments les contenant |
| NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
| GB9803228D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| ATE257480T1 (de) | 1999-09-30 | 2004-01-15 | Pfizer Prod Inc | Bicyclische pyrrolylamide als glycogenphosphorylase-inhibitoren |
| EP1136071A3 (en) | 2000-03-22 | 2003-03-26 | Pfizer Products Inc. | Use of glycogen phosphorylase inhibitors |
| EP1373204B1 (en) | 2001-03-09 | 2016-10-26 | Janssen Pharmaceuticals, Inc. | Heterocyclic compounds |
| EP1543011B1 (en) * | 2002-09-06 | 2006-05-03 | Janssen Pharmaceutica N.V. | Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands |
-
2003
- 2003-09-05 EP EP03754461A patent/EP1543011B1/en not_active Expired - Lifetime
- 2003-09-05 AT AT03754461T patent/ATE325125T1/de active
- 2003-09-05 WO PCT/US2003/028017 patent/WO2004022537A2/en not_active Ceased
- 2003-09-05 CA CA2497868A patent/CA2497868C/en not_active Expired - Fee Related
- 2003-09-05 US US10/656,059 patent/US7226938B2/en not_active Expired - Lifetime
- 2003-09-05 DE DE60305052T patent/DE60305052T2/de not_active Expired - Lifetime
- 2003-09-05 AU AU2003272285A patent/AU2003272285A1/en not_active Abandoned
- 2003-09-05 JP JP2004534722A patent/JP4596915B2/ja not_active Expired - Fee Related
- 2003-09-05 DK DK03754461T patent/DK1543011T3/da active
- 2003-09-05 PT PT03754461T patent/PT1543011E/pt unknown
- 2003-09-05 ES ES03754461T patent/ES2264534T3/es not_active Expired - Lifetime
-
2006
- 2006-07-07 CY CY20061100955T patent/CY1105080T1/el unknown
-
2007
- 2007-04-13 US US11/735,306 patent/US7645758B2/en not_active Expired - Fee Related
- 2007-04-13 US US11/735,311 patent/US20070185131A1/en not_active Abandoned
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