ATE429429T1 - Pharmazeutisches verfahren und damit hergestellte verbindungen - Google Patents
Pharmazeutisches verfahren und damit hergestellte verbindungenInfo
- Publication number
- ATE429429T1 ATE429429T1 AT04701384T AT04701384T ATE429429T1 AT E429429 T1 ATE429429 T1 AT E429429T1 AT 04701384 T AT04701384 T AT 04701384T AT 04701384 T AT04701384 T AT 04701384T AT E429429 T1 ATE429429 T1 AT E429429T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- produced therefrom
- compounds produced
- pharmaceutical process
- alkoxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 sulfinyl compound Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN58MU2003 | 2003-01-15 | ||
| IN193MU2003 | 2003-02-14 | ||
| PCT/GB2004/000064 WO2004063188A1 (en) | 2003-01-15 | 2004-01-12 | Paharmaceutical process and compounds prepared thereby |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE429429T1 true ATE429429T1 (de) | 2009-05-15 |
Family
ID=32715253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04701384T ATE429429T1 (de) | 2003-01-15 | 2004-01-12 | Pharmazeutisches verfahren und damit hergestellte verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7439367B2 (de) |
| EP (1) | EP1587805B1 (de) |
| JP (1) | JP5031362B2 (de) |
| KR (1) | KR101180530B1 (de) |
| AT (1) | ATE429429T1 (de) |
| AU (1) | AU2004203958B9 (de) |
| BR (1) | BRPI0406500A (de) |
| CA (1) | CA2513555C (de) |
| DE (1) | DE602004020730D1 (de) |
| ES (1) | ES2324665T3 (de) |
| NZ (1) | NZ541373A (de) |
| PL (1) | PL378201A1 (de) |
| RU (1) | RU2345075C2 (de) |
| WO (1) | WO2004063188A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004111029A2 (en) | 2003-06-10 | 2004-12-23 | Teva Pharmaceutical Industries Ltd. | Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
| WO2006040778A1 (en) * | 2004-10-15 | 2006-04-20 | Matrix Laboratories Ltd | Process for preparations and purification of pantoprazole sesquihydrate |
| WO2006049486A1 (en) * | 2004-11-08 | 2006-05-11 | Dishman Pharmaceuticals And Chemicals Ltd. | A PREPARATION METHOD FOR SUBSTITUTED 2-(2-PYRIDYLMETHOYLSULPHINYL)-l-H-BENZIMID AZOLES |
| ZA200706613B (en) * | 2004-12-16 | 2009-03-25 | Cipla Ltd | Process |
| AU2006242782B2 (en) | 2005-02-21 | 2010-11-04 | Cipla Limited | New process for synthesis of proton pump inhibitors |
| GB0525710D0 (en) * | 2005-12-17 | 2006-01-25 | Pliva Hrvatska D O O | An improved process for preparing of substituted 2-benzimidazolesulfoxide compounds |
| WO2008001392A2 (en) * | 2006-06-30 | 2008-01-03 | Msn Laboratories Limited | An improved process for the preparation of pantoprazole and its pharmaceutically acceptable salts |
| CN1919844B (zh) * | 2006-09-01 | 2010-05-12 | 武汉工程大学 | 水相氧化合成兰索拉唑的方法 |
| ITMI20062449A1 (it) | 2006-12-19 | 2008-06-20 | Dipharma Spa | Forma cristallina di rabeprazolo sodico |
| WO2009066317A2 (en) * | 2007-08-20 | 2009-05-28 | Macleods Pharmaceuticals Limited | Process for the preparation of pantoprazole sodium |
| FR2920428B1 (fr) * | 2007-08-29 | 2012-06-15 | Univ Rouen | Procede de dedoublement de sels de l'omeprazole |
| WO2010146428A1 (en) * | 2009-06-15 | 2010-12-23 | Orchid Chemicals And Pharmaceuticals Ltd. | An improved process for the preparation of rabeprazole |
| KR101693913B1 (ko) | 2009-07-07 | 2017-01-06 | 카운슬 오브 사이언티픽 앤드 인더스트리얼 리서치 | 설폭사이드 화합물의 제조를 위한 연속식 유동 방법 |
| CN102675285A (zh) * | 2012-06-02 | 2012-09-19 | 大连理工大学 | 一种纯水相制备雷贝拉唑钠的方法 |
| CN102952119B (zh) * | 2012-11-01 | 2014-05-07 | 江苏奥赛康药业股份有限公司 | 一种雷贝拉唑钠的制备方法 |
| WO2014091450A1 (en) | 2012-12-12 | 2014-06-19 | Ranbaxy Laboratories Limited | Process for the preparation of rabeprazole |
| EP3187494A1 (de) | 2015-12-30 | 2017-07-05 | KRKA, tovarna zdravil, d.d., Novo mesto | Verfahren zur herstellung von pantoprazole natrium sesquihydrat |
| CN107964005A (zh) * | 2017-11-10 | 2018-04-27 | 扬子江药业集团江苏海慈生物药业有限公司 | 一种兰索拉唑的制备方法 |
| CN110372667A (zh) * | 2019-08-26 | 2019-10-25 | 浙江金华康恩贝生物制药有限公司 | 一种奥美拉唑合成工艺 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
| ZA854287B (en) * | 1984-06-16 | 1986-02-26 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridines,process for their preparation,their use and medicaments containing them |
| IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| JPS62277322A (ja) * | 1986-02-13 | 1987-12-02 | Takeda Chem Ind Ltd | 安定化された腸溶性抗潰瘍固形組成物 |
| US5433959A (en) * | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
| FI96860C (fi) * | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
| JP2718945B2 (ja) * | 1987-06-17 | 1998-02-25 | エーザイ株式会社 | ピリジン誘導体及びそれを含有する潰瘍治療剤 |
| NZ244301A (en) * | 1991-09-20 | 1994-08-26 | Merck & Co Inc | Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds |
| AU698249B2 (en) | 1994-06-10 | 1998-10-29 | Altana Pharma Ag | Thiopyridines for combating (helicobacter) bacteria |
| JP3926936B2 (ja) * | 1998-11-16 | 2007-06-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホキシド誘導体・アセトン錯体およびその製造法 |
-
2004
- 2004-01-12 DE DE602004020730T patent/DE602004020730D1/de not_active Expired - Lifetime
- 2004-01-12 AU AU2004203958A patent/AU2004203958B9/en not_active Ceased
- 2004-01-12 EP EP04701384A patent/EP1587805B1/de not_active Expired - Lifetime
- 2004-01-12 US US10/542,268 patent/US7439367B2/en not_active Expired - Fee Related
- 2004-01-12 KR KR1020057013147A patent/KR101180530B1/ko not_active IP Right Cessation
- 2004-01-12 ES ES04701384T patent/ES2324665T3/es not_active Expired - Lifetime
- 2004-01-12 JP JP2006500190A patent/JP5031362B2/ja not_active Expired - Fee Related
- 2004-01-12 AT AT04701384T patent/ATE429429T1/de not_active IP Right Cessation
- 2004-01-12 NZ NZ541373A patent/NZ541373A/en not_active IP Right Cessation
- 2004-01-12 BR BRPI0406500-0A patent/BRPI0406500A/pt not_active IP Right Cessation
- 2004-01-12 WO PCT/GB2004/000064 patent/WO2004063188A1/en active Application Filing
- 2004-01-12 RU RU2005125724/04A patent/RU2345075C2/ru not_active IP Right Cessation
- 2004-01-12 CA CA2513555A patent/CA2513555C/en not_active Expired - Fee Related
- 2004-01-12 PL PL378201A patent/PL378201A1/pl not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL378201A1 (pl) | 2006-03-20 |
| US7439367B2 (en) | 2008-10-21 |
| RU2345075C2 (ru) | 2009-01-27 |
| CA2513555C (en) | 2012-09-11 |
| KR20050104349A (ko) | 2005-11-02 |
| AU2004203958B2 (en) | 2009-11-19 |
| WO2004063188A1 (en) | 2004-07-29 |
| US20060205791A1 (en) | 2006-09-14 |
| EP1587805B1 (de) | 2009-04-22 |
| EP1587805A1 (de) | 2005-10-26 |
| AU2004203958A1 (en) | 2004-07-29 |
| JP5031362B2 (ja) | 2012-09-19 |
| DE602004020730D1 (de) | 2009-06-04 |
| RU2005125724A (ru) | 2006-01-27 |
| NZ541373A (en) | 2008-11-28 |
| AU2004203958B9 (en) | 2010-07-22 |
| JP2006515353A (ja) | 2006-05-25 |
| CA2513555A1 (en) | 2004-07-29 |
| BRPI0406500A (pt) | 2008-07-22 |
| ES2324665T3 (es) | 2009-08-12 |
| KR101180530B1 (ko) | 2012-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |