JP2005532057A - 細胞を培養するための動物性タンパク質非含有培地 - Google Patents
細胞を培養するための動物性タンパク質非含有培地 Download PDFInfo
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- JP2005532057A JP2005532057A JP2004518745A JP2004518745A JP2005532057A JP 2005532057 A JP2005532057 A JP 2005532057A JP 2004518745 A JP2004518745 A JP 2004518745A JP 2004518745 A JP2004518745 A JP 2004518745A JP 2005532057 A JP2005532057 A JP 2005532057A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/74—Undefined extracts from fungi, e.g. yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39424302P | 2002-07-09 | 2002-07-09 | |
| PCT/EP2003/007341 WO2004005493A1 (en) | 2002-07-09 | 2003-07-08 | Animal protein free media for cultivation of cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010265835A Division JP5485863B2 (ja) | 2002-07-09 | 2010-11-29 | 細胞を培養するための動物性タンパク質非含有培地 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005532057A true JP2005532057A (ja) | 2005-10-27 |
| JP2005532057A5 JP2005532057A5 (enExample) | 2011-02-03 |
Family
ID=30115698
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004518745A Withdrawn JP2005532057A (ja) | 2002-07-09 | 2003-07-08 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2010265835A Expired - Lifetime JP5485863B2 (ja) | 2002-07-09 | 2010-11-29 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2011258106A Expired - Lifetime JP6084359B2 (ja) | 2002-07-09 | 2011-11-25 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2013100500A Expired - Lifetime JP6178109B2 (ja) | 2002-07-09 | 2013-05-10 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2014245252A Expired - Lifetime JP6244294B2 (ja) | 2002-07-09 | 2014-12-03 | 細胞を培養するための動物性タンパク質非含有培地 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010265835A Expired - Lifetime JP5485863B2 (ja) | 2002-07-09 | 2010-11-29 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2011258106A Expired - Lifetime JP6084359B2 (ja) | 2002-07-09 | 2011-11-25 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2013100500A Expired - Lifetime JP6178109B2 (ja) | 2002-07-09 | 2013-05-10 | 細胞を培養するための動物性タンパク質非含有培地 |
| JP2014245252A Expired - Lifetime JP6244294B2 (ja) | 2002-07-09 | 2014-12-03 | 細胞を培養するための動物性タンパク質非含有培地 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7955833B2 (enExample) |
| EP (2) | EP2287288B1 (enExample) |
| JP (5) | JP2005532057A (enExample) |
| CN (2) | CN101058800B (enExample) |
| AU (1) | AU2003249990B2 (enExample) |
| CA (1) | CA2491992A1 (enExample) |
| DK (2) | DK2287288T3 (enExample) |
| ES (2) | ES2398706T3 (enExample) |
| MX (1) | MXPA05000418A (enExample) |
| NZ (1) | NZ538094A (enExample) |
| PL (1) | PL214284B1 (enExample) |
| PT (2) | PT2287288E (enExample) |
| SI (1) | SI1520008T1 (enExample) |
| WO (1) | WO2004005493A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007125605A1 (ja) | 2006-04-28 | 2007-11-08 | Kyoritsu Seiyaku Corporation | 動物由来蛋白なしで培養可能な猫の細胞、これを用いたウイルスの生産方法、及びワクチンの生産方法 |
| JP2013106616A (ja) * | 2006-01-04 | 2013-06-06 | Baxter Internatl Inc | 無オリゴペプチド細胞培地 |
| JP2014100148A (ja) * | 2007-12-27 | 2014-06-05 | Baxter Internatl Inc | 細胞培養プロセス |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US7425437B2 (en) * | 1999-11-26 | 2008-09-16 | Crucell Holland B.V. | Vaccines against West Nile Virus |
| FR2836924B1 (fr) * | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| PT2287288E (pt) | 2002-07-09 | 2012-12-10 | Baxter Int | Meio isento de proteína animal para cultura de células |
| HRP20070474T3 (en) | 2004-03-01 | 2007-11-30 | Ares Trading S.A. | Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells |
| WO2005103235A1 (ja) * | 2004-04-19 | 2005-11-03 | Denka Seiken Co., Ltd. | ウイルスの生産方法 |
| EP2578229B1 (en) * | 2004-09-09 | 2013-07-10 | Novartis Vaccines and Diagnostics GmbH | Decreasing potential iatrogenic risks associated with vaccine antigens |
| US20060094104A1 (en) * | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| AU2011221414B2 (en) * | 2004-10-29 | 2012-09-20 | Takeda Pharmaceutical Company Limited | Animal Protein-Free Media for Cultivation of Cells |
| KR100679112B1 (ko) | 2004-11-17 | 2007-02-07 | 삼성정밀화학 주식회사 | 동물세포 배양방법 |
| CN101189326B (zh) * | 2004-12-23 | 2013-06-12 | 米迪缪尼有限公司 | 用于病毒增殖的非致瘤性mdck细胞系 |
| CA2601006C (en) * | 2005-03-10 | 2012-10-23 | Kyoritsu Seiyaku Corporation | Cell strain capable of being cultured without ingredients derived from animals, method of producing the same, method of producing virus using the same, and method of producing vaccine |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| MX2007012786A (es) * | 2005-04-13 | 2008-01-11 | Merial Ltd | Ensayo para produccion de circovirus porcino. |
| WO2006120230A2 (en) | 2005-05-12 | 2006-11-16 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
| JP2007000077A (ja) * | 2005-06-23 | 2007-01-11 | Hitachi Medical Corp | 付着性動物細胞の無血清培養方法及び付着性動物細胞の無血清培養用培地 |
| WO2007126810A2 (en) | 2006-03-31 | 2007-11-08 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
| EA018030B1 (ru) | 2006-06-06 | 2013-05-30 | Круселл Холланд Б.В. | Связывающие молекулы человека, имеющие убивающую активность против стафилококков, и их применения |
| EP2500417A1 (en) * | 2006-08-09 | 2012-09-19 | Vivalis | Method of production of transgenic avian using embryonic stem cells |
| EP2069480B1 (en) * | 2006-09-15 | 2014-03-19 | MedImmune, LLC | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
| TW200902708A (en) | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
| EP1985305A1 (en) | 2007-04-24 | 2008-10-29 | Vivalis | Duck embryonic derived stem cell lines for the production of viral vaccines |
| EP1995309A1 (en) * | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
| WO2008156778A2 (en) | 2007-06-18 | 2008-12-24 | Tokiko Watanabe | Influenza m2 protein mutant viruses as live influenza attenuated vaccines |
| EP3327132A3 (en) * | 2007-08-09 | 2018-07-18 | Wyeth LLC | Use of perfusion to enhance production of fed-batch cell culture in bioreactors |
| HUE043863T2 (hu) * | 2007-12-31 | 2019-09-30 | Baxalta GmbH | Lényegében állati fehérjétõl mentes rekombináns furin és eljárás elõállítására |
| KR101220239B1 (ko) * | 2008-04-01 | 2013-01-09 | 바이오스펙트럼 주식회사 | 식물성 펩톤을 포함하는 줄기세포 증식 촉진용 조성물 |
| TW201012930A (en) | 2008-06-16 | 2010-04-01 | Intervet Int Bv | Method of replicating viruses in suspension |
| CN103952376A (zh) | 2008-09-24 | 2014-07-30 | 米迪缪尼有限公司 | 培养细胞、增殖和纯化病毒的方法 |
| WO2011011660A2 (en) * | 2009-07-23 | 2011-01-27 | Xcellerex, Inc. | Drain down and re-feed of microcarrier bioreactor |
| WO2011056591A1 (en) | 2009-10-26 | 2011-05-12 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in vero cells |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| CN101988047B (zh) * | 2010-05-13 | 2013-07-03 | 维亚生物科技(上海)有限公司 | 一种低成本的昆虫细胞无血清培养基 |
| JP2014527799A (ja) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型pb2遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
| CN102533634A (zh) * | 2012-02-22 | 2012-07-04 | 江阴剑桥生物技术有限公司 | Cho细胞无血清无蛋白化学培养基 |
| WO2015009743A1 (en) | 2013-07-15 | 2015-01-22 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in mdck or vero cells or eggs |
| GB201321679D0 (en) * | 2013-12-09 | 2014-01-22 | Vibralogics Gmbh | Method of culturing vero cells |
| SG11201605146VA (en) | 2013-12-30 | 2016-07-28 | Baxalta GmbH | A method of predicting a performance characteristic of a plant or yeast hydrolysate and its use |
| ES2909630T3 (es) | 2014-06-04 | 2022-05-09 | Amgen Inc | Métodos de recolección en cultivos de células de mamífero |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
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| CN105154389A (zh) * | 2015-10-15 | 2015-12-16 | 南京三生生物技术有限公司 | 一种适于pk-15细胞生长的低血清无蛋白培养基及其制备方法 |
| WO2017143236A1 (en) | 2016-02-19 | 2017-08-24 | Yoshihiro Kawaoka | Improved influenza b virus replication for vaccine development |
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| CN107043740A (zh) * | 2017-05-10 | 2017-08-15 | 浙江美保龙生物技术有限公司 | 一种mdbk细胞培养液及其制备方法、使用方法 |
| US11197926B2 (en) | 2017-10-25 | 2021-12-14 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| JP7783047B2 (ja) | 2018-08-07 | 2025-12-09 | ウィスコンシン アルムニ リサーチ ファンデイション | 組換えの生物学的に封じ込められたフィロウイルスワクチン |
| JP7655849B2 (ja) | 2018-08-20 | 2025-04-02 | ウィスコンシン アルムニ リサーチ ファンデイション | ヘマグルチニン(ha)タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター |
| US12349704B2 (en) | 2018-11-15 | 2025-07-08 | Aleph Farms Ltd. | High quality cultured meat, compositions and methods for producing same |
| CN113330111A (zh) * | 2018-11-21 | 2021-08-31 | 西方溶瘤细胞有限公司 | 病毒的制造 |
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| WO2020153619A1 (ko) * | 2019-01-25 | 2020-07-30 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
| EP3921413A1 (en) | 2019-02-08 | 2021-12-15 | Wisconsin Alumni Research Foundation (WARF) | Humanized cell line |
| US11390649B2 (en) | 2019-05-01 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
| US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| IL322673A (en) | 2019-12-31 | 2025-10-01 | Air Protein Inc | High-protein food compositions |
| JP2023511444A (ja) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | 安定化されたnaを有する組換えインフルエンザウイルス |
| CN115244171A (zh) * | 2020-01-24 | 2022-10-25 | 空气蛋白公司 | 微生物来源的蛋白质水解物以及其制备方法和用途 |
| WO2021195410A1 (en) | 2020-03-25 | 2021-09-30 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| MY204715A (en) * | 2020-11-12 | 2024-09-10 | Imu Education Sdn Bhd | Culture medium for bacteria |
| KR102581772B1 (ko) * | 2021-03-30 | 2023-09-22 | 강원대학교 산학협력단 | 식물 및 곤충 단백질 가수 분해물을 이용한 배양육 제조를 위한 최적 배양 방법 및 그 응용 |
| EP4531878A1 (en) * | 2022-06-03 | 2025-04-09 | Bluerock Therapeutics LP | Cell delivery vehicle and methods of using the same |
| CN120359291A (zh) * | 2024-05-27 | 2025-07-22 | 安琪酵母股份有限公司 | 一种以蛋白水解物为核心原料的干细胞培养基制备及其应用方法 |
| CN119162122B (zh) * | 2024-09-14 | 2025-10-03 | 江苏华诺泰生物医药科技有限公司 | 一种流感病毒维持液配方及其制备方法和应用 |
| CN120738314A (zh) * | 2025-09-08 | 2025-10-03 | 安琪酵母股份有限公司 | 一种无动物源复合蛋白水解物及其制备方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996015231A2 (en) * | 1994-11-10 | 1996-05-23 | Immuno Aktiengesellschaft | Method for producing biologicals in protein-free culture |
| WO1998015614A1 (en) * | 1996-10-10 | 1998-04-16 | Life Technologies, Inc. | Animal cell culture media comprising plant-derived nutrients |
| WO2000003000A2 (en) * | 1998-07-10 | 2000-01-20 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
| JP2000517188A (ja) * | 1996-08-30 | 2000-12-26 | ライフ テクノロジーズ,インコーポレイテッド | 無血清哺乳動物細胞培養培地およびその使用 |
| WO2001023527A1 (en) * | 1999-09-28 | 2001-04-05 | Baxter Aktiengesellschaft | Medium for the protein-free and serum-free cultivation of cells |
| JP2002506636A (ja) * | 1998-03-13 | 2002-03-05 | アヴァンティ・パストゥール | ウイルスの伝播および増殖用の培地および方法 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT165999B (de) | 1947-06-26 | 1950-05-25 | Delle Atel Const Electr | Einirchtung zum Schutz von Drehstrommotoren gegen Überstrom |
| FR2196386A1 (en) | 1972-08-17 | 1974-03-15 | Cudennec Alain | Culture media selection - for identification of unknown bacteria |
| US4500513A (en) * | 1979-05-15 | 1985-02-19 | Miles Laboratories, Inc. | Influenza vaccine production in liquid cell culture |
| US4282315A (en) * | 1979-09-13 | 1981-08-04 | Corning Glass Works | Preparation of enriched whole virus radioligand |
| US4443540A (en) | 1980-05-09 | 1984-04-17 | University Of Illinois Foundation | Protein hydrolysis |
| DK207980A (da) | 1980-05-13 | 1981-11-14 | Novo Industri As | Fremgangsmaade til fremstilling af et skumnings- eller emulgeringsmiddel paa sojaproteinbasis |
| DE3122669A1 (de) * | 1980-06-12 | 1982-02-11 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | "verfahren zur herstellung von neuen mutanten von herpes simplex-viren typ 1 und typ 2" |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| CH652378A5 (de) | 1983-12-21 | 1985-11-15 | Heinrich Nagel Ag Wislikofen | Einrichtung zum absaugen und zerkleinern von in einem gasfoermigen medium foerderbarem material. |
| FI86885C (fi) | 1984-04-20 | 1992-10-26 | Genentech Inc | Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill |
| EP0217822B1 (en) | 1985-02-13 | 1993-05-12 | Scios Nova Inc. | Human metallothionein-ii promoter in mammalian expression system |
| US4978616A (en) | 1985-02-28 | 1990-12-18 | Verax Corporation | Fluidized cell cultivation process |
| JP2520681B2 (ja) | 1986-08-04 | 1996-07-31 | ザ ユニバーシティ オブ ニュー サウス ウェールズ | 生合成のヒトの成長ホルモン製品 |
| US4710282A (en) | 1986-08-08 | 1987-12-01 | Maryan Chak | Device for siliverizing running water |
| JPH03500529A (ja) * | 1987-06-18 | 1991-02-07 | モナシュ ユニバーシティ | 増殖因子 |
| WO1989000192A1 (en) | 1987-06-30 | 1989-01-12 | Amgen Inc. | Production of kallikrein |
| JP2507882B2 (ja) | 1988-02-17 | 1996-06-19 | 工業技術院長 | 外部増殖因子非依存性増殖良好細胞株の製造法 |
| JPH01211878A (ja) | 1988-02-19 | 1989-08-25 | Fujitsu Ltd | I/oピンの修復方法 |
| US6048728A (en) | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
| US5573937A (en) | 1989-12-07 | 1996-11-12 | Snow Brand Milk Products Co., Ltd. | Serum free culture medium |
| SE465222C5 (sv) | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
| WO1991010726A1 (en) | 1990-01-22 | 1991-07-25 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Co-independent growth medium for maintenance and propagation of cells |
| JP2844484B2 (ja) | 1990-02-22 | 1999-01-06 | 味の素株式会社 | 組換え蛋白質の生産方法 |
| JP2859679B2 (ja) | 1990-03-01 | 1999-02-17 | 協和醗酵工業株式会社 | 新規細胞株 |
| JP2696001B2 (ja) | 1991-04-15 | 1998-01-14 | 財団法人化学及血清療法研究所 | 組換え蛋白質産生用培地 |
| US5378612A (en) | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| JPH04228066A (ja) | 1990-10-23 | 1992-08-18 | Rikagaku Kenkyusho | 外来遺伝子発現用培養細胞 |
| US5213795A (en) * | 1990-10-24 | 1993-05-25 | Oxford | Encephalomyocarditis virus vaccine |
| EP0531562A1 (de) | 1991-09-11 | 1993-03-17 | Doerr, Hans-Wilhelm, Prof. Dr. med. | Kultivierung von Säugetierzellen |
| JPH05123178A (ja) | 1991-11-01 | 1993-05-21 | Ajinomoto Co Inc | L−フエニルアラニンの製造法 |
| JP3511399B2 (ja) * | 1993-03-31 | 2004-03-29 | 株式会社三菱化学ヤトロン | 細胞培養基材及び細胞培養方法 |
| AU7895898A (en) | 1993-04-26 | 1998-10-08 | Hans Wolf | Mammal cell lines and method of obtaining glycoproteins |
| DE4313620A1 (de) | 1993-04-26 | 1994-10-27 | Biotechnolog Forschung Gmbh | Hamsterzellinien und Verfahren zur Glykoproteingewinnung |
| US5405637A (en) | 1993-06-30 | 1995-04-11 | Bristol-Myers Squibb Company | Milk protein partial hydrolysate and infant formula containing same |
| JP4098372B2 (ja) | 1993-07-28 | 2008-06-11 | 三菱化学株式会社 | ヘパリン結合性増殖因子の生産方法 |
| JP2766165B2 (ja) | 1993-08-02 | 1998-06-18 | 株式会社バイオポリマー・リサーチ | バクテリアセルロースの製造方法 |
| US5833162A (en) * | 1993-12-22 | 1998-11-10 | Daewoo Electronics Co., Ltd. | Reel table driving device for a video cassette recorder |
| US5719050A (en) | 1993-12-24 | 1998-02-17 | Eiken Chemical Co., Ltd. | Animal cell culturing media containing N-acetyl-L-glutamic acid |
| EP0666312A1 (en) | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Process for the improvement of mammalian cell growth |
| US5789247A (en) | 1994-04-01 | 1998-08-04 | Ballay; Annick | Expression in non-tumoral human lymphoblastoid lines with an integrative vector |
| WO1996007730A2 (de) | 1994-09-09 | 1996-03-14 | Renner Wolfgang A | Chemisches verfahren zur förderung der proliferation von tierischen zellen |
| US5753489A (en) * | 1994-11-10 | 1998-05-19 | Immuno Ag | Method for producing viruses and vaccines in serum-free culture |
| AT403167B (de) | 1994-11-14 | 1997-11-25 | Immuno Ag | Selektion und expression von fremdproteinen mittels eines selektions-amplifikations-systems |
| JP3244391B2 (ja) | 1994-12-08 | 2002-01-07 | 財団法人国際超電導産業技術研究センター | 複合基板及びそれを用いた単結晶基板の製造方法 |
| WO1996018734A1 (en) | 1994-12-16 | 1996-06-20 | Novartis Ag | Production of recombinant secretory component |
| EP0811056B1 (en) | 1995-02-23 | 2000-05-31 | Quest International B.V. | Peptides for tissue and cell culture media |
| US5741705A (en) | 1995-02-23 | 1998-04-21 | Quest International Flavors & Food Ingredients Company, Division Of Indopco, Inc. | Method for in vitro cell growth of eucaryotic cells using low molecular weight peptides |
| AU6125396A (en) | 1995-06-07 | 1996-12-30 | Novartis Ag | Serum-free media for primitive hematopoietic cells and metho ds of use thereof |
| CA2223484A1 (en) | 1995-06-07 | 1996-12-19 | Thomas Jefferson University | Anti-fungal agents and methods of identifying and using the same |
| AUPN442295A0 (en) | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
| US5851800A (en) | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
| US5804420A (en) | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
| EP2267113B1 (en) | 1997-05-28 | 2013-07-17 | Novartis AG | Culture medium for Neisseria meningitidis with soy bean extract as amino acid source and no protein complexes of animal origin |
| AT407255B (de) | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| ATE341625T1 (de) | 1997-07-23 | 2006-10-15 | Roche Diagnostics Gmbh | Herstellung von erythropoietin durch endogene genaktivierung mit viralen promotoren |
| JPH11211488A (ja) | 1998-01-21 | 1999-08-06 | Matsushita Electric Ind Co Ltd | 携帯情報端末を用いたデータ転送システム |
| WO1999057246A1 (en) | 1998-05-01 | 1999-11-11 | Life Technologies, Inc. | Animal cell culture media comprising non-animal or plant-derived nutrients |
| EP1200561B1 (de) | 1999-08-05 | 2006-06-14 | Baxter Aktiengesellschaft | Rekombinanter stabiler zellklon, seine herstellung und verwendung |
| NZ529329A (en) | 1999-08-25 | 2005-06-24 | Immunex Corp | Compositions and methods for improved cell culture |
| US7425437B2 (en) * | 1999-11-26 | 2008-09-16 | Crucell Holland B.V. | Vaccines against West Nile Virus |
| JP2001211878A (ja) * | 2000-02-04 | 2001-08-07 | National Federation Of Dairy Cooperative Associations | ヨーグルトスターター乳酸菌の高濃度培養方法、及び得られた高濃度培養液を用いたヨーグルトの製造方法 |
| US7494659B2 (en) | 2000-09-25 | 2009-02-24 | Polymun Scientific Immunbiologische Forschung Gmbh | Live attenuated influenza vaccine |
| EP1208966A1 (en) | 2000-11-27 | 2002-05-29 | Cheng-Kun Liao | Manufacturing process of patio tabletop glass with broken protection |
| PT2287288E (pt) | 2002-07-09 | 2012-12-10 | Baxter Int | Meio isento de proteína animal para cultura de células |
| JP4316484B2 (ja) | 2004-12-10 | 2009-08-19 | シャープ株式会社 | 画像形成装置、トナー濃度制御方法、トナー濃度制御プログラムおよびその記録媒体 |
-
2003
- 2003-07-08 PT PT100105840T patent/PT2287288E/pt unknown
- 2003-07-08 CA CA 2491992 patent/CA2491992A1/en not_active Abandoned
- 2003-07-08 US US10/614,037 patent/US7955833B2/en not_active Expired - Lifetime
- 2003-07-08 ES ES10010584T patent/ES2398706T3/es not_active Expired - Lifetime
- 2003-07-08 DK DK10010584T patent/DK2287288T3/da active
- 2003-07-08 EP EP20100010584 patent/EP2287288B1/en not_active Expired - Lifetime
- 2003-07-08 CN CN2007101019058A patent/CN101058800B/zh not_active Expired - Lifetime
- 2003-07-08 PL PL374782A patent/PL214284B1/pl unknown
- 2003-07-08 MX MXPA05000418A patent/MXPA05000418A/es active IP Right Grant
- 2003-07-08 NZ NZ538094A patent/NZ538094A/en not_active IP Right Cessation
- 2003-07-08 ES ES03762657T patent/ES2394085T3/es not_active Expired - Lifetime
- 2003-07-08 CN CN03821326A patent/CN100591759C/zh not_active Expired - Lifetime
- 2003-07-08 SI SI200332208T patent/SI1520008T1/sl unknown
- 2003-07-08 AU AU2003249990A patent/AU2003249990B2/en not_active Expired
- 2003-07-08 EP EP20030762657 patent/EP1520008B1/en not_active Expired - Lifetime
- 2003-07-08 WO PCT/EP2003/007341 patent/WO2004005493A1/en not_active Ceased
- 2003-07-08 DK DK03762657T patent/DK1520008T3/da active
- 2003-07-08 JP JP2004518745A patent/JP2005532057A/ja not_active Withdrawn
- 2003-07-08 PT PT03762657T patent/PT1520008E/pt unknown
-
2010
- 2010-11-29 JP JP2010265835A patent/JP5485863B2/ja not_active Expired - Lifetime
-
2011
- 2011-05-06 US US13/102,765 patent/US8524497B2/en not_active Expired - Fee Related
- 2011-11-25 JP JP2011258106A patent/JP6084359B2/ja not_active Expired - Lifetime
-
2013
- 2013-05-10 JP JP2013100500A patent/JP6178109B2/ja not_active Expired - Lifetime
- 2013-08-06 US US13/960,481 patent/US9163211B2/en not_active Expired - Lifetime
-
2014
- 2014-12-03 JP JP2014245252A patent/JP6244294B2/ja not_active Expired - Lifetime
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996015231A2 (en) * | 1994-11-10 | 1996-05-23 | Immuno Aktiengesellschaft | Method for producing biologicals in protein-free culture |
| JP2000517188A (ja) * | 1996-08-30 | 2000-12-26 | ライフ テクノロジーズ,インコーポレイテッド | 無血清哺乳動物細胞培養培地およびその使用 |
| WO1998015614A1 (en) * | 1996-10-10 | 1998-04-16 | Life Technologies, Inc. | Animal cell culture media comprising plant-derived nutrients |
| JP2002506636A (ja) * | 1998-03-13 | 2002-03-05 | アヴァンティ・パストゥール | ウイルスの伝播および増殖用の培地および方法 |
| WO2000003000A2 (en) * | 1998-07-10 | 2000-01-20 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
| WO2001023527A1 (en) * | 1999-09-28 | 2001-04-05 | Baxter Aktiengesellschaft | Medium for the protein-free and serum-free cultivation of cells |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013106616A (ja) * | 2006-01-04 | 2013-06-06 | Baxter Internatl Inc | 無オリゴペプチド細胞培地 |
| JP2017055770A (ja) * | 2006-01-04 | 2017-03-23 | バクスアルタ ゲーエムベーハー | 無オリゴペプチド細胞培地 |
| WO2007125605A1 (ja) | 2006-04-28 | 2007-11-08 | Kyoritsu Seiyaku Corporation | 動物由来蛋白なしで培養可能な猫の細胞、これを用いたウイルスの生産方法、及びワクチンの生産方法 |
| US7767451B2 (en) | 2006-04-28 | 2010-08-03 | Kyoritsu Seiyaku Corporation | Feline cell capable of being cultured without animal-derived protein, and method for producing virus and method for producing vaccine using thereof |
| JP4881946B2 (ja) * | 2006-04-28 | 2012-02-22 | 共立製薬株式会社 | 動物由来蛋白なしで培養可能な猫の細胞、これを用いたウイルスの生産方法、及びワクチンの生産方法 |
| JP2014100148A (ja) * | 2007-12-27 | 2014-06-05 | Baxter Internatl Inc | 細胞培養プロセス |
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