JP2005518208A5 - - Google Patents
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- Publication number
- JP2005518208A5 JP2005518208A5 JP2003571408A JP2003571408A JP2005518208A5 JP 2005518208 A5 JP2005518208 A5 JP 2005518208A5 JP 2003571408 A JP2003571408 A JP 2003571408A JP 2003571408 A JP2003571408 A JP 2003571408A JP 2005518208 A5 JP2005518208 A5 JP 2005518208A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- protein
- nucleotide sequence
- chimeric
- apv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 241000700605 Viruses Species 0.000 claims 51
- 241000351643 Metapneumovirus Species 0.000 claims 19
- 239000002773 nucleotide Substances 0.000 claims 19
- 125000003729 nucleotide group Chemical group 0.000 claims 19
- 241001519465 Avian metapneumovirus Species 0.000 claims 15
- 229960005486 vaccine Drugs 0.000 claims 13
- 241000282414 Homo sapiens Species 0.000 claims 9
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 9
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 8
- 238000009472 formulation Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 5
- 241000712005 Bovine respirovirus 3 Species 0.000 claims 4
- 108091006027 G proteins Proteins 0.000 claims 4
- 102000030782 GTP binding Human genes 0.000 claims 4
- 108091000058 GTP-Binding Proteins 0.000 claims 4
- 206010057190 Respiratory tract infections Diseases 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 230000002163 immunogen Effects 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 4
- 241000283690 Bos taurus Species 0.000 claims 3
- 241001494479 Pecora Species 0.000 claims 3
- 230000002238 attenuated effect Effects 0.000 claims 3
- 230000004048 modification Effects 0.000 claims 3
- 238000012986 modification Methods 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 241000282472 Canis lupus familiaris Species 0.000 claims 2
- 241000283707 Capra Species 0.000 claims 2
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 2
- 241000282326 Felis catus Species 0.000 claims 2
- 241000712003 Human respirovirus 3 Species 0.000 claims 2
- 108091029795 Intergenic region Proteins 0.000 claims 2
- 101150039699 M2-1 gene Proteins 0.000 claims 2
- 101150103632 M2-2 gene Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 101710141454 Nucleoprotein Proteins 0.000 claims 2
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 102100034574 P protein Human genes 0.000 claims 2
- 101710181008 P protein Proteins 0.000 claims 2
- 101710177166 Phosphoprotein Proteins 0.000 claims 2
- 241000288906 Primates Species 0.000 claims 2
- 108020004511 Recombinant DNA Proteins 0.000 claims 2
- 241000283984 Rodentia Species 0.000 claims 2
- 101001039853 Sonchus yellow net virus Matrix protein Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000010362 genome editing Methods 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 241000271566 Aves Species 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 241000283073 Equus caballus Species 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 206010061598 Immunodeficiency Diseases 0.000 claims 1
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 241000282898 Sus scrofa Species 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 238000010322 bone marrow transplantation Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35893402P | 2002-02-21 | 2002-02-21 | |
| PCT/US2003/005276 WO2003072720A2 (en) | 2002-02-21 | 2003-02-21 | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005518208A JP2005518208A (ja) | 2005-06-23 |
| JP2005518208A5 true JP2005518208A5 (https=) | 2006-01-05 |
| JP4553589B2 JP4553589B2 (ja) | 2010-09-29 |
Family
ID=27766025
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571408A Expired - Fee Related JP4553589B2 (ja) | 2002-02-21 | 2003-02-21 | 組換えパラインフルエンザウイルス発現系とメタニューモウイルスから得られる異種抗原を含むワクチン |
| JP2003571407A Expired - Fee Related JP4553588B2 (ja) | 2002-02-21 | 2003-02-21 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
| JP2009035820A Expired - Fee Related JP4982514B2 (ja) | 2002-02-21 | 2009-02-18 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
| JP2012016062A Pending JP2012105661A (ja) | 2002-02-21 | 2012-01-30 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571407A Expired - Fee Related JP4553588B2 (ja) | 2002-02-21 | 2003-02-21 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
| JP2009035820A Expired - Fee Related JP4982514B2 (ja) | 2002-02-21 | 2009-02-18 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
| JP2012016062A Pending JP2012105661A (ja) | 2002-02-21 | 2012-01-30 | メタニューモウイルス（ｍｅｔａｐｎｅｕｍｏｖｉｒｕｓ）株と、ワクチン製剤でのおよび抗原配列発現用ベクターとしてのその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (11) | US7449324B2 (https=) |
| EP (3) | EP1485468A4 (https=) |
| JP (4) | JP4553589B2 (https=) |
| KR (2) | KR101151822B1 (https=) |
| CN (2) | CN101098958A (https=) |
| AR (4) | AR038596A1 (https=) |
| AU (2) | AU2003219837B2 (https=) |
| CA (3) | CA2477234C (https=) |
| IL (2) | IL163646A0 (https=) |
| MX (1) | MXPA04008088A (https=) |
| TW (4) | TWI359868B (https=) |
| WO (2) | WO2003072720A2 (https=) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060094105A1 (en) | 1998-04-24 | 2006-05-04 | University Hospitals Of Cleveland | Mixed cell diagnostic systems for detection of respiratory, herpes and enteric viruses |
| US6764685B1 (en) * | 2000-03-21 | 2004-07-20 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines |
| US20040096451A1 (en) * | 2002-07-25 | 2004-05-20 | Young James F. | Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies |
| US8715922B2 (en) * | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| KR20040002853A (ko) | 2001-01-19 | 2004-01-07 | 비로노바티브 비.브이. | 감응성 포유류에서 호흡계 질환을 유발하는 바이러스 |
| US20030232061A1 (en) * | 2001-10-18 | 2003-12-18 | Fouchier Ronaldus Adrianus Maria | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| EP1485468A4 (en) | 2002-02-21 | 2007-01-03 | Medimmune Vaccines Inc | RECOMBINANT PARAIN FLUENZAVIRUS EXPRESSION SYSTEMS AND VACCINES WITH ANTIGENS FROM METAPNEUMOVIRUS STEM-RELATED HETEROLOGISTS |
| AU2003297602A1 (en) * | 2002-12-02 | 2004-06-23 | University Of Maryland, College Park | Avian pneumovirus genes, recombinant avian pneumoviruses and methods of making |
| US7704491B2 (en) * | 2003-02-28 | 2010-04-27 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant human metapneumovirus and its use |
| EP1622574A4 (en) * | 2003-04-25 | 2006-10-18 | Medimmune Vaccines Inc | EXPRESSION SYSTEMS OF RECOMBINANT PARAINFLUENZA VIRUSES AND VACCINES COMPRISING HETEROLOGOUS ANTIGENS DERIVED FROM METAPNEUMOVIRUS |
| CN101410519B (zh) * | 2003-04-25 | 2013-04-24 | 免疫医疗有限责任公司 | 间质肺病毒株及其在疫苗制剂中以及用作抗原性序列表达载体的用途和繁殖病毒的方法 |
| US7588770B2 (en) | 2003-12-10 | 2009-09-15 | The Uab Research Foundation | Recombinant viruses of the paramyxoviridae family with heterologous envelope glycoproteins |
| EP2295542B1 (en) * | 2004-12-24 | 2013-01-30 | Abbott Biologicals B.V. | Rescue of influenza virus |
| CA2600484A1 (en) * | 2005-03-10 | 2006-09-21 | Medimmune Vaccines, Inc. | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| JP4976376B2 (ja) * | 2005-04-08 | 2012-07-18 | メディミューン，エルエルシー | 哺乳動物メタニューモウイルスに対する抗体 |
| US7682619B2 (en) | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
| US8492097B2 (en) | 2006-04-24 | 2013-07-23 | Diagnostic Hybrids, Inc. | Compositions and methods for human metapneumovirus monoclonal antibodies |
| US20080213749A1 (en) * | 2007-03-02 | 2008-09-04 | Melanie Feola | Compositions and methods for detecting human metapneumovirus |
| US20090017517A1 (en) * | 2007-07-13 | 2009-01-15 | Medimmune, Llc | Preparation of Negative-Stranded RNA Viruses by Electroporation |
| AU2008299104A1 (en) * | 2007-09-10 | 2009-03-19 | Intervet International B.V. | Compositions and methods for preventing influenza infection in canines, felines and equines |
| US20090186050A1 (en) * | 2007-11-16 | 2009-07-23 | Fouchier Ron A M | Live attenuated metapneumovirus strains and their use in vaccine formulations and chimeric metapneumovirus strains |
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| CA2768186A1 (en) | 2009-07-15 | 2011-01-20 | Novartis Ag | Rsv f protein compositions and methods for making same |
| CN103977394B (zh) * | 2009-07-17 | 2016-03-09 | 翰林大学校产学协力团 | 包含脂质体包胶的寡核苷酸和表位的免疫刺激性组合物 |
| KR101073991B1 (ko) * | 2009-10-27 | 2011-10-21 | 대한민국 | 국내사육 닭에서 유행하는 신규한 ｂ형 조류메타뉴모바이러스 ｓｃ1509주 및 이의 용도 |
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| WO2012089231A1 (en) * | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
| JP5807917B2 (ja) * | 2011-02-08 | 2015-11-10 | 国立大学法人三重大学 | 遺伝子導入用ウイルスベクターの製造方法 |
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| WO2012116714A1 (en) | 2011-03-02 | 2012-09-07 | Curevac Gmbh | Vaccination in elderly patients |
| CA2835644C (en) | 2011-05-13 | 2021-06-15 | Novartis Ag | Pre-fusion rsv f antigens |
| CN102676701B (zh) * | 2012-06-11 | 2013-08-14 | 广东温氏食品集团股份有限公司 | 禽肺病毒通用型rt-pcr检测引物及检测方法 |
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| EP2970398B1 (en) | 2013-03-13 | 2024-05-08 | The United States of America, as Represented by The Secretary, Department of Health and Human Services | Prefusion rsv f proteins and their use |
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| CL2013002829A1 (es) * | 2013-10-01 | 2014-04-04 | Univ Pontificia Catolica Chile | Formulacion inmunogenica que contiene bcg vivas recombinantes que expresan antigenos de metapneumovirus (hmpv) en una suspension que se prepara a partir de un liofilizado sin la necesidad de adjuvante; su uso farmaceutico; vacuna contra hmpv. |
| EP2873728A1 (en) * | 2013-11-18 | 2015-05-20 | Institut Pasteur | A subunit vaccine platform based on multimeric ribonucleoproteins comprising nucleoproteins of a non-segmented negative-strand RNA virus as carriers of heterologous polypeptides |
| KR101577397B1 (ko) * | 2014-01-15 | 2015-12-28 | 경북대학교 산학협력단 | 신규한 돼지 파라인플루엔자 바이러스 5(pPIV5), 이를 포함하는 백신 조성물 및 이를 이용한 돼지 파라인플루엔자 바이러스 검정 키트 |
| AU2015244700B2 (en) * | 2014-04-10 | 2020-08-27 | Riken | Compositions and methods for induction of Th17 cells |
| DK3247388T3 (da) | 2015-01-20 | 2025-12-22 | Us Health | Rekombinant human/bovin parainfluenzavirus 3 (b/hpiv3), der udtrykker et kimærisk rsv/bpiv3 f-protein, og anvendelser deraf |
| JPWO2016199936A1 (ja) * | 2015-06-12 | 2018-04-05 | 国立大学法人三重大学 | ヒトパラインフルエンザ２型ウイルスベクター及びワクチン |
| CL2015002152A1 (es) * | 2015-07-31 | 2016-06-03 | Pontificia Universidad Católica De Chile | Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh |
| EP4011451A1 (en) | 2015-10-22 | 2022-06-15 | ModernaTX, Inc. | Metapneumovirus mrna vaccines |
| WO2017172890A1 (en) | 2016-03-29 | 2017-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Substitutions-modified prefusion rsv f proteins and their use |
| CN106282407A (zh) * | 2016-08-11 | 2017-01-04 | 青岛易邦生物工程有限公司 | 一种b亚群禽肺病毒疫苗的效检方法 |
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| US11084850B2 (en) | 2016-12-16 | 2021-08-10 | The Pirbright Institute | Recombinant prefusion RSV F proteins and uses thereof |
| JOP20190256A1 (ar) | 2017-05-12 | 2019-10-28 | Icahn School Med Mount Sinai | فيروسات داء نيوكاسل واستخداماتها |
| US11273214B2 (en) | 2017-05-29 | 2022-03-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing RSV G and its use |
| CN111344008A (zh) * | 2017-09-15 | 2020-06-26 | 俄亥俄州创新基金会 | 用于预防呼吸道合胞病毒(rsv)感染的疫苗及其制备和使用方法 |
| FR3084079A1 (fr) | 2018-07-23 | 2020-01-24 | Universite Claude Bernard Lyon 1 | Nouvelle souche virale attenuee et son utilisation en tant que vaccin |
| WO2020037215A1 (en) | 2018-08-17 | 2020-02-20 | Icahn School Of Medicine At Mount Sinai | Recombinant newcastle disease viruses and uses thereof for the prevention of rsv disease or human metapneumovirus disease |
| FR3089789B1 (fr) | 2018-12-14 | 2022-05-27 | Univ Claude Bernard Lyon | Production de vaccins viraux sur une lignee cellulaire aviaire |
| EP3923983A4 (en) * | 2019-02-11 | 2023-02-22 | Emory University | CHIMERIC RSV AND HMPV F PROTEINS, IMMUNOGENIC COMPOSITIONS AND METHODS OF USE |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| CN109851678A (zh) * | 2019-03-07 | 2019-06-07 | 苏州宇之波生物科技有限公司 | 一种改良的亚稳定态牛呼吸道合胞病毒融合前体f蛋白质及编码的dna分子和其应用 |
| KR102860080B1 (ko) | 2020-10-09 | 2025-09-15 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 융합전-안정화된 hmpv f 단백질 |
| CN117729935A (zh) | 2021-04-27 | 2024-03-19 | 美国政府(由卫生和人类服务部的部长所代表) | 表达sars-cov-2刺突蛋白的重组嵌合牛/人副流感病毒3及其用途 |
| WO2022258755A1 (en) | 2021-06-09 | 2022-12-15 | Universität Duisburg-Essen | Method for immortalising vesicle-secreting cells |
| MX2024006506A (es) | 2021-11-30 | 2024-08-14 | Sanofi Pasteur Inc | Vacunas basadas en vectores virales de metapneumovirus humano. |
| WO2026080706A1 (en) | 2024-10-10 | 2026-04-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant chimeric bovine/human parainfluenza virus 3 expressing avian influenza virus proteins and use thereof |
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